Increase In Frequency Research Articles

Angioedema due to acquired C1-inhibitor deficiency associated with monoclonal gammopathies of undetermined significance

No specific description of monoclonal gammopathies of undetermined significance (MGUS)-associated angioedema due to acquired C1 inhibitor deficiency (AAE-C1-INH) has been reported yet. Describe the biological and clinical characteristics, evolution and response to treatment of MGUS-associated AAE-C1-INH. We conducted a French national retrospective observational study on MGUS-associated acquired angioedema spanning a 30-year period. Forty-one patients with MGUS-associated AAE-C1-INH at diagnosis were included; 68% displayed anti-C1INH antibodies. The monoclonal component was an IgM in 24 patients, IgG in 11 and IgA in 6 patients. Mean age at first angioedema attack was 63 years (SD = 13) and at diagnosis 66 years (SD = 11). 88 % of patients benefited from acute attack treatments, and 77% from long-term prophylaxis, either danazol, tranexamic acid or lanadelumab. Median follow-up was 7 years, during which 14 patients (33%) evolved into well-defined malignant hemopathies. 50 % of patients were given a hematological treatment, either rituximab alone, indicated by recurrent attacks of angioedema in patients with AAE-C1-INH with anti-C1-INH antibodies, or validated combinations of chemotherapies, indicated by evolution into a lymphoma in 7 patients and a myeloma in 3 patients. Fifteen patients (35%) were in clinical complete remission of angioedema at last visit, of which 60% had an undetectable serum monoclonal immunoglobulin. Complete remission of AAE-C1-INH is correlated to complete remission of the underlying hematological malignancy, as defined by an undetectable serum monoclonal immunoglobulin. In our MGUS-associated acquired angioedema cohort, we recorded an incidence of evolution into hematological malignancy of 4% per patient-year. It is therefore crucial to conduct full hematological workup during follow-up at an annual rate, and earlier if AAE relapses or if acute attacks frequency increases.

Spatiotemporal variation and teleconnections of extreme precipitation in the Upper Indus Basin: insights for natural hazard assessment

ABSTRACT The study investigates trends and teleconnections of extreme precipitation events in the Upper Indus Basin (UIB) within the Indian region, part of the crucial geo-ecological Hindu Kush Himalayan Mountain system. Utilizing high-resolution (10 km × 10 km) HAR data from 2002 to 2013, we analyzed 11 indices established by the Expert Team on Climate Change Detection and Indices (ETCCDI) to observe variations in extreme precipitation at the monthly, seasonal, and annual time scale. The result shows an increase in dry and wet extreme precipitation frequency and intensity, increasing monsoon precipitation and a shift of winter precipitation, increasing continuous dry days. Using the APHRODITE daily (0.25° × 0.25°) data from 1952 to 2014, continuous wavelet transform and wavelet coherence analysis indicate significant periodicities and correlations with large-scale climate anomalies such as the El Niño-Southern Oscillation (ENSO) and North Atlantic Oscillation (NAO). Wavelet coherence analysis reveals that monthly extreme precipitation events significantly correlate with ENSO at a 3–5 years periodicity, while annual extremes show significant coherence with NAO at 8–10 years and over 16 years periodicities. The study highlights the impact of global climate change on regional precipitation and the need for adaptive water management policies to mitigate flood risks during the rainy season and address water scarcity in the dry season.

Does wildlife-vehicle collision frequency increase on full moon nights? A case-crossover analysis

Wildlife-vehicle collisions (WVCs) raise concerns for both human safety and animal welfare. As the literature has reported increased animal-related crash frequency on full moon nights in several regions, we investigated if a similar pattern is observed in Texas. We counted WVC and non-WVC frequencies on full moon nights and new moon nights in Texas between January 2011 and January 2020. The analysis revealed a 45.80% (95% confidence interval (CI): 29.94%–61.29%) increase in WVCs on full moon nights compared to new moon nights, with no statistically significant difference for non-WVCs (95% CI: -2.58%–1.45%). The association was more pronounced in rural areas than in urban areas. It is likely that brighter moonlight is strongly associated with higher WVC rates. The results illuminate the importance of heightened caution for drivers even on bright nights, particularly when driving through areas with high wildlife density.

Circadian control of polycyclic aromatic hydrocarbon-induced dysregulation of endothelial tight junctions and mitochondrial bioenergetics

The study evaluates the impact of environmental toxicants, such as polycyclic aromatic hydrocarbons (PAHs), on circadian regulations and functions of brain endothelial cells, which form the main structural element of the blood-brain barrier (BBB). PAH are lipophilic and highly toxic environmental pollutants that accumulate in human and animal tissues. Environmental factors related to climate change, such as an increase in frequency and intensity of wildfires or enhanced strength of hurricanes or tropical cyclones, may lead to redistribution of these toxicants and enhanced human exposure. These natural disasters are also associated with disruption of circadian rhythms in affected populations, linking increased exposure to environmental toxicants to alterations of circadian rhythm pathways. Several vital physiological processes are coordinated by circadian rhythms, and disruption of the circadian clock can contribute to the development of several diseases. The blood-brain barrier (BBB) is crucial for protecting the brain from blood-borne harmful substances, and its integrity is influenced by circadian rhythms. Exposure of brain endothelial cells to a human and environmentally-relevant PAH mixture resulted in dose-dependent alterations of expression of critical circadian modulators, such as Clock, Bmal1, Cry1/2, and Per1/2. Moreover, silencing of the circadian Clock gene potentiated the impact of PAHs on the expression of the main tight junction genes and proteins (namely, claudin-5, occludin, JAM-2, and ZO-2), as well as mitochondrial bioenergetics. Findings from this study contribute to a better understanding of pathological influence of PAH-induced health effects, especially those related to circadian rhythm disruption.

The impacts of climate change on meteorological drought in the Central Highlands region of Vietnam

ABSTRACT This study aimed to analyse the characteristics of drought under the impacts of climate change in the Central Highlands of Vietnam. The standardized precipitation indices at 3-, 6-, 9- and 12-month time scales were calculated based on the average monthly precipitation at 11 meteorological stations between 1985–2014. The drought characteristics were analysed based on the modified Mann-Kendall test, Theil-Sen methods and the theory of runs. Analysing the impact of climate change on drought events, four CMIP6 GCM models, namely, CNRM-CM6-1-HR, MRI-ESM2-0, BCC-CSM2-MR and MIROC6, under the SSP2-4.5 and SSP5-8.5 scenarios were used to obtain the average monthly precipitation for the period 2031-2060 to compute the SPI3, SPI6, SPI9 and SPI12. The results indicate that the drought frequency under the SSP5-8.5 scenario ranges from moderate to severe. The BCC-CSM2-MR, CNRM-CM6-1-HR and MIROC6 models showed an increase in drought frequency from 2 to 4% for SPI3 and SPI6 and from 4 to 6% for SPI9 and SPI12. Under the SSP2-4.5 scenario, the frequency of severe droughts also increases by 2-4% compared with that in the 1985-2014 baseline periods for SPI6, SPI9 and SPI12. Consequently, moderate to severe drought episodes are predicted to occur more frequently in the research area.

Dynamic and Phase-Frequency Characteristics of Rotor Instability Induced by Steam Flow Excited Vibration in Seals

Steam flow excited vibration in seals seriously affects the seal-rotor stability. A mesh deformation based on user-defined functions was adopted to establish the multi-frequency whirl model, and the reliability of the simulation method was verified by experiments. The average effective damping and working ability of the fluid were proposed to analyse the stability of the seal. The mechanism of seal instability induced by steam flow excited vibration was revealed through the phase-frequency characteristics of exciting forces and displacements. The results show that direct damping decreases gradually with an increase in frequency, and the cross-coupling damping tends to be stable over 15 Hz. The average effective damping is more sensitive and accurate in predicting the seal stability. Effective damping decreases with increased frequency. Therefore, the rotor stability is decreased. Near the 12 Hz and 24 Hz frequencies, the average effective damping of eccentricity fluctuates, so the seal stability is poor. The negative effect of exciting forces increases, and the seal stability is improved when the eccentricity increases. When the phase difference between the excitation force and displacement changes, the seal stability decreases. The fundamental reason for rotor instability induced by steam flow excited vibration in seals is the sharp changes of phase difference caused by pressure fluctuations.

On quadrature of highly oscillatory Bessel function via asymptotic analysis of simplex integrals

In this article, two methods for evaluating highly oscillatory Bessel integrals are explored. Firstly, a polynomial is analyzed as an effective approximation of the simplex integral of a highly oscillatory Bessel function based on Laplace transform, and its error rapidly decreases as the frequency increases. Furthermore, the inner product of f and highly oscillatory Bessel function can be approximated by two other forms of inner product by which one depends on a polynomial and the higher derivatives of f, another depends on Bessel function and the interpolation polynomial of f. In addition, three issues related to highly oscillatory Bessel integrals have also been discussed: inequalities for the convergence rate of Filon-type methods, evaluation of Cauchy principal values, and simplified evaluation on infinite intervals. Through some preliminary numerical experiments, our theoretical analysis has been preliminarily confirmed, and the proposed numerical method is accurate and effective.

Poweromin X Ten, a polyherbal formulation improves male sexual function: In vivo and network pharmacology study.

Poweromin X Ten (PXT) is a polyherbal formulation, traditionally used to enhance male sexual function. However, the safety and benefits of PXT have not been scientifically evaluated. Therefore, the present study investigated the toxicity and aphrodisiac potential of PXT in male rats and explored its principal mechanisms of action. Male Wistar rats were orally administered PXT (50 or 100 mg/kg) for 28 days, and sexual activity parameters, including latency and frequency of mounting and intromissions, were studied. The reproductive toxicity and spermatogenic potential were also examined. Furthermore, dopamine and serotonin levels in brain regions associated with sexual activity were assessed. Network analysis was used to identify the key bioactive compounds and their core targets involved in their beneficial actions. Treatment with PXT improved sexual activity in male rats, as evidenced by reduced mounting and intromission latency and a significant increase in mount frequency. Moreover, PXT exhibited spermatogenic potential and did not induce reproductive toxicity. Notably, treatment with 50 mg/kg PXT elevated dopamine levels in median preoptic area and hypothalamus. Pathway analysis indicated that PXT primarily modulated the PI3K-Akt, calcium, and MAPK signalling pathways to enhance male sexual function. Network analysis identified macelignan, β-estradiol, testosterone, and paniculatine as key bioactive components of PXT, which likely act through core targets, such as androgen receptor (AR), Mitogen-activated protein kinase 3 (MAPK3), epidermal growth factor receptor (EGFR), estrogen receptor 1 (ESR1), and vascular endothelial growth factor (VEGF) to facilitate the improvement of male sexual function. Study results suggest that PXT is a safer alternative with aphrodisiac and spermatogenic potential. These effects are partly attributed to the enhanced dopamine levels in the brain. Furthermore, this study provides insights into the specific signalling pathways and bioactive compounds that underlie the improvements in male sexual function associated with PXT.

Study on the Effect of Starved Lubrication on the Dynamic Characteristics of Locally Failed Roller Bearings

When the lubricant is not enough to maintain the ideal lubrication state of the bearing, the deep groove ball bearing will enter the starved lubrication state, which leads to the change of the vibration response of the deep groove ball bearing with localized defects. Previous bearing dynamics models mainly consider the lubrication state as an ideal lubrication condition, which may not reveal the effect of starved lubrication on the vibration characteristics of defective bearings. In this paper, the internal interaction of the system under starved condition is taken into account, and a dynamic model of defective deep groove ball bearings with insufficient lubricant is established to investigate the effects of different starved lubrication degrees on the contact force, friction force, cage speed, and system vibration characteristics. The results show that the lubricant insufficiency significantly changes the contact force inside the bearing, and the increase in friction caused by the increase in the degree of starved lubrication leads to the suppression of the degree of bearing slipping. The root mean square (RMS) value of the time-domain signal and the outer ring fault frequency both increase with the increase of the starved degree. The results of the study are helpful for fault diagnosis and condition monitoring of related equipment.

Measuring Vibrations of Subway Tunnel Structures with Cracks

In a study conducted in a metro tunnel, acceleration and displacement sensors were strategically placed along steel rails, track beds, and tunnel walls to capture real-time dynamic responses during train operations. Data were analyzed in the time and frequency domains, focusing on vibration levels and one-third octave bands. The results indicated that peak vibration acceleration significantly decreases from steel rails to tunnel walls, with different vibration frequencies observed at various locations: steel rails (200 Hz–1400 Hz), track beds, and tunnel walls (70 Hz–400 Hz). Cracks notably increase peak acceleration, vibration levels, peak frequency, and steel rail displacement but do not alter the overall vibration trends. Tunnel wall responses show the highest sensitivity to cracks, with a 300% increase in peak frequency, followed by track beds (100%) and steel rails (70%). Vibration levels under one-third octave band processing increased by 12.4% for tunnel walls, 8.8% for track beds, and 2.2% for steel rails. Cracks also caused steel rails’ vertical and lateral displacement to rise by 112% and 53%, respectively. These findings provide valuable insights for vibration reduction and crack repair in long-term subway operations.

Exploring climate shifts in the Ganga-Brahmaputra basin based on rainfall and temperature variability.

Climate change has a significant impact on the Ganga-Brahmaputra (GB) basin, the major food belt of India, which frequently experiences flooding and varied incidences of drought. The current study examines the changing trend of rainfall and temperature in the GB basin over a period of 30years to identify areas at risk with an emphasis on the Paris Agreement's mandate to keep increasing temperatures below 2°C. The maximum temperature anomaly in the middle Ganga plains recorded an increase of more than 1.5°Cyear-1 in 1999, 2005, and 2009. Some extreme events were observed in the Brahmaputra basin during 1999, 2009, and 2010, where a prominent temperature increase of 1.5°Cyear-1 was observed. The minimum temperature revealed an increasing trend for the G-B basin with an anomalous increase of 0.04 to 0.06°Cyear-1. The rainfall variability across the Ganga basin shows a rising tendency over the lower Ganga region while the Brahmaputra basin showed a downward trend. To identify the statistical relation between the Global climatic oscillations and regional climate, Standardized Precipitation Index (SPI) and Niño 3.4 were used. The wet and dry period estimation shows a rise in flood conditions in the Ganga basin whereas, in the Brahmaputra basin, an increase in drought frequency was observed. The correlation based on Niño 3.4 and SPI3 presents a negative relation for the monsoon season in the G-B basin revealing a situation of drought occurrence (SPI3 below 0) with increased Nino 3.4 values (El Niño above + 0.4C).

Effect of oscillation parameters on weld surface morphology during laser beam oscillation welding of stainless steel

During laser beam oscillation welding (LBOW), the weld surface morphology is important because it influences the appearance of the workpiece and reflects the welding quality, and the oscillation parameters have an important effect on the weld surface morphology. Therefore, a combination of experimental research and numerical simulation is conducted to investigate the influence of oscillation parameters, including oscillation mode, oscillation frequency, and oscillation amplitude, on the weld surface morphology during LBOW. The calculation encompasses the oscillation trajectory, combined velocity, and energy distribution on the weld surface, varying with different oscillation parameters. A three-dimensional heat transfer and fluid flow model with the oscillation heat source is established to simulate the temperature and fluid flow behavior inside the weld pool. When the heat input is constant, an increase in oscillation frequency results in a decrease in weld width and a smoother surface. As the oscillation frequency increases, the weld width decreases, the surface becomes smooth, and the energy distribution on the weld surface becomes more uniform. The fact that the period of the surface pattern is almost equal to the oscillation period indicates a direct correlation between the formation of weld surface pattern and the oscillation trajectory in LBOW. Among all the oscillation modes, the minimum combined velocity which is equal to the welding velocity occurs at the inflection point in the linear oscillation mode, and the variation in combined velocity of the laser beam is the smallest for circular oscillation mode. The surface pattern is primarily influenced by the oscillation trajectory and fluid flow within the weld pool. Under conditions of lower oscillation frequencies or larger oscillation amplitudes, the fluid flow is weaker, and the surface pattern is primarily influenced by the oscillation trajectory. Conversely, when the fluid flow is stronger, the surface pattern is mainly determined by the fluid flow within the weld pool under conditions of higher oscillation frequencies or smaller oscillation amplitudes. This study explains the formation mechanisms of weld surface patterns and provides insights and guidance for selecting optimal oscillation parameters in LBOW.

Establishment and evaluation of dynamic viscoelasticity constitutive model for asphalt mixtures based on PCA model: Utilizing coal-based synthetic natural gas slag and phosphogypsum whisker as substitute fillers

To promote the secondary utilization of solid waste in asphalt pavement and reduce resource waste and environmental damage, the fine solid waste powder from the secondary treatment of solid waste was used as a substitute filler to prepare asphalt mixtures. To more precisely characterize the effects of filler type and substitution ratio on the dynamic viscoelastic mechanical characteristics of asphalt mixtures, the dynamic modulus test was conducted on asphalt mixtures, while the dynamic modulus master curve of asphalt mixtures was established based on the time-temperature equivalent principle and the Sigmoidal function. The improved generalized Sigmoidal (IGS) model, five-parameter fractional Zener (FFZ) model, six-parameter fractional Zener (SFZ) model and ten-parameter fractional Zener (TFZ) model were used to construct the shrinkage frequency curves of different asphalt mixtures under different constitutive relationships, whereas the applicability of the constitutive models was further evaluated by the principal component analysis (PCA) model. The research results showed that the dynamic modulus and phase angle of the mixture exhibited a similar change rule with the variation of temperature and frequency, and the use of solid waste-based fillers could effectively reduce the effect of frequency variation on the viscoelasticity of the mixture. The dynamic modulus master curve constructed by Sigmoidal function could accurately describe the functional relationship between the dynamic modulus with loading frequency and temperature, and the variation trend of dynamic modulus in a wider frequency range was flattened with the increase in frequency, and this change rule was not affected by the substitution ratio of the filler, while the use of solid waste-based filler could reduce the dependence of the mixture on the temperature. Compared to several fractional constitutive models, the IGS model exhibited a higher fitting accuracy for the dynamic viscoelasticity of several mixtures, and with the use of solid waste-based fillers, the deviation of fitting curves gradually decreased. A comparative study showed that the fractional constitutive model was difficult to accurately describe the dynamic viscoelasticity of the mixture, and the IGS model was preferred to be recommended as a calculation model to investigate the constitutive relationship on the dynamic viscoelasticity of the mixture.

Pandemic of sensitivity to acrylate containing nail cosmetic among young Israeli women? Result of patch testing 2-hydroxyethyl methacrylate in the European baseline series.

2-Hydroxyethyl methacrylate (HEMA) was added into the European baseline series (EBS) in 2019. There is limited data regarding the frequency, relevance, and sources of exposure to HEMA. To investigate the frequency and clinical relevance of positive reactions to HEMA in the EBS in Israel, and explore sources of exposure. Retrospective cohort study that included all patients who underwent patch testing with the EBS in a tertiary center in Israel between 2020 and 2023. Positive reactions to HEMA were stratified by sex, six age groups, and year of study. Sources of exposure to HEMA as well as occupational data were recorded. A total of 1671 consecutive patients underwent HEMA patch testing, with 135 (8.1%) showing positive reactions to HEMA (130 females, 5 males). The prevalence in women (11.0%) was significantly higher compared to men (1.0%) (p < 0.001). Stratification by age and sex revealed the highest frequency of HEMA sensitivity of 16.7% among women younger than 30 years of age, with odds ratio of 2.3 (95%CI: 1.6-3.3, p < 0.001) compared to older women. There was an increase in frequency among women between the years 2022 and 2023 when compared to 2020-2021 (OR 1.7, 95%CI: 1.5-2.1, p < 0.01) attributable to COVID-19 pandemic and social restrictions. Among men the frequency fluctuations over the study period and age categories were nonsignificant. 111 (84%) were judged to be of clinical relevance and nail cosmetics was responsible for 95% of them. Of 111 patients with relevant reaction (110 females, 1 males), 20 (18%) had occupational contact dermatitis (18 nails stylists, 2 dentists). Other culprit products included sanitary pads (n = 4), medical adhesives (n = 3), and paints (n = 2). We report the highest frequency of HEMA sensitivity to date of 8.1%, that was most common among young women and in vast majority of cases was attributable to nail cosmetics. Our findings reflect the popularity of nail cosmetics in Israel as well as the global trend of increasing sensitivity to (meth)acrylates.

Increase of coastal shark bite frequency linked to the COVID-19 lockdown reveals a territoriality-dominance behaviour toward humans

Increase of coastal shark bite frequency linked to the COVID-19 lockdown reveals a territoriality-dominance behaviour toward humans

Aqua jet integrated fiber laser machining of quaternary NiTiCuZr alloy

ABSTRACT Low thermal diffusivity of NiTi-based smart alloy results in concentrated heat accumulation during laser beam machining which rises to adverse thermal effects like heat-affected zones, residual stresses, and alterations in microstructure of shape memory alloy (SMA) system. The addition of Cu and Zr can reduce the thermal hysteresis in the phase transformation of NiTi SMAs. Minimizing thermal hysteresis is desirable in SMA applications where precise control of the phase transformation temperatures is required, such as in actuators, sensors, and medical devices. Therefore, aqua jet integrated laser (AJ-FLBM) machining is a suitable choice for smart materials that need to be machined with high precision and low heat affected zone. In this current research, the NiTiCuZr SMA is machined using AJ-FLBM to investigate the effects of process variables on surface characteristics measured using RSM-BBD approach. The surface quality was enhanced by 68.93% with a gradual decrease in laser power (P), cutting speed (CS), and an increase in frequency (F). Aqua jet integrated FLBM technique may reduce heat affected zone due to the removal of heat in areas near the cutting location. This was confirmed by the DSC test which reveals that optimal machining inputs do not alter shape memory properties.

Analysing the capacity of multispectral indices to map the spatial distribution of potential post-fire soil losses based on soil burn severity

The area burned in Spain exceeded historical records in 2022, when exceptionally warm conditions influenced wildfire events. The predicted intensification of wildfire regimes includes an increase in frequency, severity, and size. Therefore, a study of the wildfires that occurred in 2022 is necessary to understand their behaviour and possible environmental impacts. The objective of this study is to analyse the applicability of using spectral indices and Geographic Information System (GIS) approaches to map the spatial distribution and estimate potential soil losses using Sentinel-2 imagery and fire severity field data. Soil losses were estimated using an empirical model based on soil burn severity data collected in the field after wildfire. The relationship between the Normalized Difference Infrared Index (NDII), Difference Normalized Wildfire Ash Index (dNWAI), and the Blue Normalized Difference Vegetation Index (BNDVI) with the estimated soil losses was then evaluated. In addition, the influence of different time scales of the satellite images was analysed. The first period considered (Date I) ranges from 8 to 20 days after the beginning of the wildfire, which coincides with the field data collection. The second period considered (Date II) ranges from 28 to 35 days after the start of the wildfire. The results obtained showed a significant dependence relationship between the BNDVI index (using satellite images of Date I) and the estimated soil losses (R2 = 0.756), while the results of the NDII (R2 = 0.31) and dNWAI (R2 = 0.061), showed no spatial relationship with the estimated soil losses. Three of the largest wildfires in 2022 in Spain were analysed, and the results showed strong correlations of BNDVI index for Folgoso do Courel (R2 = 0.808), for Carballeda de Valedorras (R2 = 0.906), and for Sierra de la Culebra (R2 = 0.939). In addition, these results allowed the mapping and quantification of potential soil losses in areas where fire severity was high, totalling ∼2,50,000 Mg ha−1 in Folgoso do Courel, ∼3,70,000 Mg ha−1 in Carballeda de Valdeorras, and ∼4,70,000 Mg ha−1 in Sierra de la Culebra. Moreover, BNDVI values for estimating soil loss vary by vegetation type, and there is a positive correlation between severity classes and the BNDVI index. This approach can inform post-fire land management decisions in future wildfires and could be applied to other regions.

Role of periodic oscillating flow modulators on mixed convection in a long horizontal channel

Present study explores mixed convection characteristics in a long horizontal channel subjected to multiple periodically distributed flow modulators. The flow modulators are represented by oscillating blades placed along a centerline of the channel whose lower and upper walls are kept at constant high and low temperatures respectively. In replicating the blade oscillation, moving mesh approach has been adopted within Arbitrary Lagrangian–Eulerian (ALE) framework for a representative periodical unit. The corresponding non-dimensional governing mass, momentum and energy conservation equations have been solved through Galerkin finite element solver for a wide variations of modulator's dynamic condition (oscillating frequency and maximum angular displacement) for different fluids represented by Prandtl number. Heat transfer performance of the system has been demonstrated in terms of spatially-averaged transient as well as time-averaged Nusselt number while qualitative analysis of fluid flow and thermal field has been presented as streamline and isotherm plots. Present study indicates that the time averaged Nusselt number undergoes significant variation with blade oscillating frequency and maximum angular displacement depending on both the Prandtl number and Reynolds Number. Power spectrum analysis obtained through Fast Fourier Transformation (FFT) of the imposed blade frequency and induced thermal frequency reveals different correlation depending on the blade frequency. Blade friction power requirement has been found to increase at higher blade frequency as well as maximum angular displacement. However, contrary to power consumption, increase in frequency does not result in a significant rise in heat transfer. Consequently, specific heat transfer decreases at higher blade oscillating frequency and maximum angular displacement.

Bi-Directional and Operand-Controllable In-Memory Computing for Boolean Logic and Search Operations with Row and Column Directional SRAM (RC-SRAM).

The von Neumann architecture is no longer sufficient for handling large-scale data. In-memory computing has emerged as the potent method for breaking through the memory bottleneck. A new 10T SRAM bitcell with row and column control lines called RC-SRAM is proposed in this article. The architecture based on RC-SRAM can achieve bi-directional and operand-controllable logic-in-memory and search operations through different signal configurations, which can comprehensively respond to various occasions and needs. Moreover, we propose threshold-controlled logic gates for sensing, which effectively reduces the circuit area and improves accuracy. We validate the RC-SRAM with a 28 nm CMOS technology, and the results show that the circuits are not only full featured and flexible for customization but also have a significant increase in the working frequency. At VDD = 0.9 V and T = 25 °C, the bi-directional search frequency is up to 775 MHz and 567 MHz, and the speeds for row and column Boolean logic reach 759 MHz and 683 MHz.

Variation in vessel traits of northern red oak (Quercus rubra L.) provenances revealed high phenotypic plasticity to prevailing environmental conditions

Key messageRed oak provenances responded with high plasticity and intra-annual variability in vessel traits to studied climatic conditions, indicating weak signals of local adaptation and providing opportunities for forest management.The climate change-induced increase in frequency and severity of extreme events has revealed a high vulnerability of various major tree species in Europe, stressing the need for selecting climate-resilient species for forest management. In this context, adaptive strategies of northern red oak (Quercus rubra L.) were examined, using wood anatomical data derived from a provenance trial. We investigated the interannual variation in vessel traits of red oak provenances planted at three sites along a precipitation gradient in Germany. We compared the climate sensitivity of German provenances with those from North America to analyze plasticity and to identify signals of local adaptation in vessel traits. The results revealed variations in vessel traits between all sites, pointing to site-specific responses to prevailing environmental conditions. Differences between provenances were prevalent for vessel size-related traits, with site-specific higher values for German provenances at wet sites. Climate signals, which varied between traits, were strongest for vessel density and the relative conductive area. Vessel traits were found to depend both on previous-year conditions as and on spring climate conditions during the onset of vessel formation. The site-specific response in extreme years deviate significantly between drought and frost events. A trade-off between resistance to extremes and vessel diameter could not be demonstrated, and provenances with larger vessel diameters showed higher frost resistance. The observed high plasticity in vessel traits and the site-specific variation to climate influences point to an adjustment in vessel formation to the prevailing environmental conditions.