Athletes widely use nutritional supplements to increase muscle strength and endurance. This review aims to summarize the effects of commonly used dietary supplements on muscle strength and endurance in athletes. A literature search identified several dietary supplements studied for their impact on muscle performance, including protein supplements, creatine, beta-alanine, branched-chain amino acids (BCAAs), caffeine, nitrates, and vitamins and minerals. The review discussed the mechanisms by which this supplement affects muscle strength and endurance. The review methodology includes a systematic literature search, study selection, and data analysis. The review summarizes the effects of each type of supplement on muscle strength and endurance based on the available literature. The discussion includes an overview of the effectiveness and safety of using nutritional supplements to increase muscle strength and endurance in athletes, as well as limitations of studies reviewed and directions for future research. In conclusion, this review highlights the importance of choosing the right and safe nutritional supplements to improve muscle performance in athletes.