Increase Muscle Strength Research Articles

Analysis of the Effectiveness of High-Intensity Interval Training Methods in Improving Basketball Players Fitness

This research aims to analyze the effectiveness of High-Intensity Interval Training (HIIT) in improving the fitness of basketball players. Employing a literature review methodology, this study explores recent findings related to the application of HIIT in the context of basketball sports. The literature analysis involves searching and screening various scientific articles covering aspects such as improved cardiorespiratory fitness, muscle strength, time efficiency, and safety considerations. The results indicate that HIIT holds significant potential in enhancing the cardiorespiratory fitness of basketball players, with positive effects on aerobic capacity and cardiorespiratory endurance. Furthermore, HIIT has also shown a positive impact on increasing muscle strength and endurance. The effectiveness of HIIT can be observed in its time efficiency, as this high-intensity training program can deliver significant results in a shorter time compared to conventional training methods. However, the study also highlights the importance of considering the risks and safety considerations in implementing HIIT, emphasizing the need for an individualized approach and careful monitoring. Thus, this research provides a solid foundation for the development of more focused and effective training programs to enhance the performance of basketball players. The practical implications of these findings can assist coaches and fitness professionals in designing exercise programs tailored to the specific needs of basketball players, taking into account cardiorespiratory aspects, muscle strength, time efficiency, and safety.

The Range of Motion (ROM) in Increasing Muscle Strength in Stroke Patients : Literature Review

Background: Proper care is essential for the prevention of mental and physical impairment in patients with Sroke illness. There is a golden time of less than six hours during which people can recuperate fully after a stroke. Disability and physical weakening, including a loss of muscle strength, may occur if treatment is not maximized within that time frame. The purpose of the literature review is to determine the importance of Range of Motion (ROM) in Increasing Muscle Strength in Stroke Patients. Methods: Use PRISMA Approach. The research stage is to make selections by paying attention to the quality of the journal. Furthermore, articles from journals that are considered less relevant are excluded. Literature obtained from 7 articles relevant to Google Scholar, Indonesia One Search, DOAJ, and Garuda with the keywords Range of Motion, Muscle Strength, Stroke. Results: After a review of selected articles, the results given Range of Motion have a good impact on increasing muscle strength in stroke patients. Conclusion: The Range of Motion (ROM) can be applied in health program for in Increasing Muscle Strength in Stroke Patients

Penatalaksanaan Fisioterapi Pada Kondisi Drop Foot Bilateral dengan Modalitas Infra Red, TENS dan Terapi Latihan

Drop Foot is someone who is unable to lift the front foot when walking. This incident is reported to be around 19 per 100,000 people or 1% to 2% of all diagnosed sufferers. The aim of this research is to determine the management of physiotherapy with pain problems, limited range of motion of joints and decreased muscle strength. These problems are the reason researchers use selected modalities such as Infra Red, TENS and exercise therapy in the form of an ankle pump from February to March at the Bagas Waras Regional Hospital, Klaten. Collecting case study data on physiotherapy treatment using Infra Red modalities, TENS and exercise therapy in the form of an Ankle pump which resulted in reducing pressure pain in the 6th therapy (T6) to 1 from 4 (T0), increasing the range of joint movement by 5° at each meeting on the left side, as well as increasing muscle strength at the 6th therapy (T6) to a value of 3 from 1 (T0). Researchers advise the public to reduce activities such as lifting heavy weights in order to reduce the occurrence of spondylosis so that the number of Drop Foot cases does not continue to increase.

Penatalaksanaan Fisioterapi Pada kasus Post ORIF Metacarpal IV Sinistra dengan modalitas Infra Red(IR) dan Terapi Latihan

Based on 2018 Riskesdas data, an average of 92,976 fractures occurred, totaling 5,144 people. A single trauma and sudden excess force can cause a fracture. Orif installation is carried out if the use of close reduction/plaster fails, Orif is installed on the right fracture fragment. In solving problems in post-orif cases, physiotherapy plays a role in restoring movement and function using infrared modalities and exercise therapy. The energy produced by IR can be absorbed by superficial tissue with a warm feeling, thereby reducing pain. Exercise therapy using active and passive body movements can increase the range of motion of joints, increase muscle strength values ​​to restore functional ability. This research method uses a case study of physiotherapy management in Post Orif Metacarpal IV cases with Infra Red (IR) and Exercise Therapy. Results were obtained such as pressure pain from T0:3 decreased to T6:1, movement pain T0:5 decreased to T6:1. The muscle strength value of left wrist flexor T0:3 increased to T6:5, extensor T0: 3 increased to T6: 5 in left wrist flexor T0: 3 increased to T6: 5, extensor T0: 3 increased to T6:4. Left wrist joint range of motion from T0 (S: 20°-0°-15°) increases to T6 (S: 50°-0°-50°) at T0 left mcp (S: 10°-0°-20°) increases to T6:(S:45°-0°-40°), functional activity from T0:(severe dependence) increases to T6:(light dependence). Being more careful in activities and not pushing your abilities can reduce the incidence of fractures.

Acute Whole-Body Vibration Does Not Alter Passive Muscle Stiffness in Physically Active Males

Whole-body vibration (WBV) is a widely used training method to increase muscle strength and power. However, its working mechanisms are still poorly understood, and studies investigating the effects of WBV on muscle stiffness are scant. Therefore, the aim of this study is to investigate the acute effects of WBV on stiffness and countermovement jump (CMJ). Twenty-four recreationally active males, on separate days and in random order, performed a static squat under two different conditions: with WBV (WBV) or without vibration (CC). Muscle stiffness was assessed through the Wartenberg pendulum test, and CMJ was recorded. RM-ANOVA was employed to test differences between conditions in the above-mentioned variables. In the CC condition, stiffness was significantly lower after the exposure to the static squat (p = 0.006), whereas no difference was observed after the exposure to WBV. WBV and CC did not affect CMJ. No significant correlation was observed between changes in CMJ and changes in stiffness. Our results show that WBV may mitigate the reduction in muscle stiffness observed after static squats. However, current results do not support the notion that WBV exposure may account for an increase in CMJ performance.

Long-Term High-Intensity Plyometric Training Increases Muscle Strength and Power of The Lower Body in Young Healthy Males

Long-Term High-Intensity Plyometric Training Increases Muscle Strength and Power of The Lower Body in Young Healthy Males

High-quality research on physical therapy in psoriatic arthritis is needed: a systematic review.

Although physical therapy is recommended as part of the non-pharmacological management of patients with psoriatic arthritis (PsA), the evidence is still unclear. Therefore, this study aimed to systematically review and appraise the quality of research on physical therapy in the management of patients with PsA. In June 2024, a systematic literature search using four different databases (Medline, Embase, Web of Science and the Cochrane Library) was performed to include interventional and observational studies examining physical therapy in patients with PsA (PROSPERO ID 255501). A risk of bias assessment was conducted. Due to the wide variety of interventions and outcomes, a narrative synthesis was used. Of 9442 abstracts, 15 papers examining physical therapy uptake in clinical practice (N = 2) and different physical therapy interventions (N = 13) were included: cardiorespiratory exercises (N = 5), resistance exercises (N = 2), therapeutic modalities (N = 4) and mixed rehabilitation programs (N = 2). A low risk of bias was scored in only one RCT assessing cardiorespiratory exercises. The well-tolerated 11-week high-intensity interval training resulted in a long-term increase in peak oxygen uptake and a short-term decrease in truncal fat percentage in patients with low disease activity. Resistance training in patients with active disease did not increase muscle strength, but improved functional capacity, disease activity, pain and general health after the intervention. Evidence for other modalities was inconclusive. High-quality evidence on physical therapy in PsA was scarce. Cardiorespiratory and resistance exercises demonstrated promising results to positively influence cardiometabolic risk as well as disease-related outcomes. Future research on physical therapy in PsA with adequate methodological quality is needed.

Testosterone deficiency promotes arterial stiffening independent of sex chromosome complement

BackgroundSex hormones and sex chromosomes play a vital role in cardiovascular disease. Testosterone plays a crucial role in men’s health. Lower testosterone level is associated with cardiovascular and cardiometabolic diseases, including inflammation, atherosclerosis, and type 2 diabetes. Testosterone replacement is beneficial or neutral to men’s cardiovascular health. Testosterone deficiency is associated with cardiovascular events. Testosterone supplementation to hypogonadal men improves libido, increases muscle strength, and enhances mood. We hypothesized that sex chromosomes (XX and XY) interaction with testosterone plays a role in arterial stiffening.MethodsWe used four core genotype male mice to understand the inherent contribution of sex hormones and sex chromosome complement in arterial stiffening. Age-matched mice were either gonadal intact or castrated at eight weeks plus an additional eight weeks to clear endogenous sex hormones. This was followed by assessing blood pressure, pulse wave velocity, echocardiography, and ex vivo passive vascular mechanics.ResultsArterial stiffening but not blood pressure was more significant in castrated than testes-intact mice independent of sex chromosome complement. Castrated mice showed a leftward shift in stress–strain curves and carotid wall thinning. Sex chromosome complement (XX) in the absence of testosterone increased collagen deposition in the aorta and Kdm6a gene expression.ConclusionTestosterone deprivation increases arterial stiffening and vascular wall remodeling. Castration increases Col1α1 in male mice with XX sex chromosome complement. Our study shows decreased aortic contractile genes in castrated mice with XX than XY sex chromosomes.Graphical

The offsetting relationship between hand grip strength and hypertension: A cross-sectional study from physically disabled over 50 years old in China.

To explore the relationship between hand grip strength (HGS) and blood pressure in physically disabled individuals over 50 years old. The research adopts a cross-sectional survey, and the data comes from the "2022-2023 Physical Health Monitoring and Scientific and Technological Services for Physical Disabilities" jointly carried out by Beijing Sport University and China Disabled Sports Management Center. Select physically disabled individuals over 50 years old and collect physical fitness measurement data. HGS was measured and adjusted based on body weight and waist circumference, with standard normal conversion. The relationship between HGS and blood pressure was analyzed using multiple linear regression, and further logistic regression was used to analyze the relationship between standard HGS and the risk of abnormal blood pressure. 695 disabled individuals participated in the experiment, including 402 males (57.84%) and 293 females (42.16%). Multiple linear regression analysis found that for each standard deviation increase in the standardized Z-value of relative HGS, the systolic and diastolic blood pressure of male individuals decreased by 2.391 mmHg (P = 0.008) and 1.229 mmHg (P = 0.025); decreased by 2.336 mmHg (P = 0.026) and 1.585 mmHg (P = 0.008), respectively, for female. The increase in HGS reduced the risk of hypertension in physical disabilities in males [OR = 0.820 95%CIs (0.670, 0.952)] (P = 0.003) and females [OR = 0.735 95%CIs (0.472, 0.986)] (P = 0.007). The HGS of middle-aged and elderly physically disabled individuals negatively correlates with blood pressure, indicating the importance of increasing muscle strength (HGS) in preventing blood pressure.

Metabolic effects of training with blood flow restriction

Relevance. Training with limited blood flow, which is performed with partial vascular occlusion using inflatable cuffs, can cause an increase in skeletal muscle mass and strength, similar to those observed with classical high-intensity training with weights, although with a noticeably lower mechanical load. Performing a load with a restriction of blood flow leads to the accumulation of metabolites, recruitment of motor neurons with a higher excitation threshold, edema of muscle cells, an increase in the concentration of reactive oxygen species, which, in turn, contributes to hypertrophy of muscle fibers, increased muscle strength, mitochondrial biogenesis, angiogenesis, increased activity of glucose transporters. Based on this, training with limited blood flow should have a positive effect on metabolic health.The aim of the study is a theoretical analysis of the metabolic effects of blood flow restriction training in healthy individuals and in clinical populations.Methods and organization of the study - this review examines the metabolic effects of TOK in both healthy and clinical populations.Conclusions. BFR can be considered as a potential method for improving muscle function and metabolism of glucose, triglycerides and fatty acids.

Operative Repair of Hamstring Injuries From the Jackling Position in Rugby.

The jackling position within rugby has not been previously described as a mechanism for proximal hamstring injuries. Acute surgical repair of proximal hamstring avulsion injuries sustained from the jackling contact position enables a return to a previous level of sporting activity with low risk of recurrence. Case series; Level of evidence, 4. This study included 54 professional rugby players (mean age, 26 ± 4.8 years) who underwent acute primary surgical repair of complete, proximal hamstring avulsion injuries. The mean follow-up time was 17 months (range, 12-24 months). Mean isometric hamstring strength and function testing was performed at 3 months and 1 year after repair. Of the 54 players, 51 (94.4%) returned to their preinjury level of sporting activity. The mean time from surgical repair to full sporting activity was 7 months (range, 4-12 months). No patients had recurrence of the primary injury. At 1 year postoperatively, patients had significantly restored mean isometric hamstring muscle strength when compared with the uninjured leg at 0° (98.4% ± 2.8%), 15° (95.9% ± 2.9%), and 45° (92.9% ± 4.1%); improved Lower Extremity Functional Score (78.0 ± 2.0); and improved Marx activity rating score (14.3 ± 1.5) (P < .001 for all). Acute surgical repair of proximal hamstring avulsion injuries caused by the contact jackling position produced a high return to preinjury level of sporting activity, increased muscle strength, and improved functional outcome scores, with a low risk of recurrence at short-term follow-up.

Minimum Intensity of Daily Six Eccentric Contractions to Increase Muscle Strength and Size.

Our previous study showed that daily six maximal eccentric contractions that were performed 5 days a week for 4 weeks increased maximal voluntary isometric (MVC-ISO), concentric (MVC-CON), and eccentric contraction (MVC-ECC) strength of the elbow flexors and muscle thickness of biceps brachii and brachialis (MT) by 8.3 ± 4.9%, 11.1 ± 7.4%, 13.5 ± 11.5%, and 10.6 ± 5.1%, respectively. In the present study, we tested the hypothesis that the muscle strength and MT would still increase when the training intensity was reduced to 2/3 or 1/3 of the peak MVC-ECC torque. Thirty-six healthy young (19-24 years) adults who had not performed resistance training were placed to three groups (n = 12/group): 2/3MVC or 1/3MVC that performed six eccentric contractions with 2/3 or 1/3 MVC-ECC load using a dumbbell 5 days a week for 4 weeks or control group that did not perform any training. Changes in the MVC-ISO, MVC-CON, MVC-ECC torque, and MT before and after the 4-week period were compared among the groups and with the group of the previous study in which six maximal eccentric contractions were performed 5 days a week for 4 weeks (MVC group; n = 12). The control and 1/3MVC groups showed no significant changes in any measures. Significant (p < 0.05) increases in MVC-ISO (10.3 ± 11.4%), MVC-CON (10.9 ± 9.5%), and MVC-ECC (9.3 ± 8.8%) torque and MT (10.1 ± 9.2%) were observed for the 2/3MVC group. These changes were not significantly different from those of the MVC group. These results suggest that the 2/3-intensity eccentric contractions with a dumbbell are as effective as maximal-intensity isokinetic eccentric contractions to induce muscle adaptations.

Impact of low-load resistance exercise with and without blood flow restriction on muscle strength, endurance, and oxidative capacity: A pilot study.

Low-load resistance exercise (LLRE) to failure can increase muscle mass, strength, endurance, and mitochondrial oxidative capacity (OXPHOS). However, the impact of adding blood flow restriction to low-load resistance exercise (LLBFR) when matched for volume on these outcomes is incompletely understood. This pilot study examined the impact of 6 weeks of single-legged LLBFR and volume-matched LLRE on thigh bone-free lean mass, strength, endurance, and mitochondrial OXPHOS. Twenty (12 males and 8 females) untrained young adults (mean ± SD; 21 ± 2 years, 168 ± 11 cm, 68 ± 12 kg) completed 6 weeks of either single-legged LLBFR or volume-matched LLRE. Participants performed four sets of 30, 15, 15, and 15 repetitions at 25% 1-RM of leg press and knee extension with or without BFR three times per week. LLBFR increased knee extension 1-RM, knee extension endurance, and thigh bone-free lean mass relative to control (all p < 0.05). LLRE increased leg press and knee extension 1-RM relative to control (p = 0.012 and p = 0.054, respectively). LLRE also increased mitochondrial OXPHOS (p = 0.047 (nonparametric)). Our study showed that LLBFR increased muscle strength, muscle endurance, and thigh bone-free lean mass in the absence of improvements in mitochondrial OXPHOS. LLRE improved muscle strength and mitochondrial OXPHOS in the absence of improvements in thigh bone-free lean mass or muscle endurance.

#2892 The role of physical activity in onco-nephrology; a new weapon in the management of urological malignancies

Abstract Background and Aims New clinical evidence demonstrated that Physical Activity (PA) brings numerous benefits both at the level of Health-RelatedQuality of Life (HRQoL), biological mechanisms and at the psychological level. Indeed, it is well known that cancer treatments results in a series of symptoms and side effects that debilitates the patients with cancer and can be counteracted with physical activity. PA has an effect on several aspects of biological mechanisms: sex hormones, metabolic hormones, inflammation and adiposity, and immune function. Furthermore, strong evidence shows that aerobic or combined (aerobic and endurance) training reduces symptoms of anxiety, depression and fatigue. Combined training also leads to improvements in HRQoL, preventing and improving muscle loss and sarcopenia. This study aims to assess the influence of physical activity on this improved scenario. Method A consecutive cohort of 82 pts was enrolled in the Urological Department at San Raffaele Scientific Institute between 2018-2021. The control group (CT) was composed of 31 patients affected by CKD alone (GFR &amp;lt; 60 ml/min/1.73 m2, K-DIGO 2012 classification) and 51 patients with CKD and a recent history of urological malignancies (within 12 months) represented the case group (CS). Inclusion criteria were: Age (&amp;gt;18 years old), eGFR (&amp;lt;60 ml/min/1.73), Malnutritional Screening Tool (MST&amp;lt;2), Urological Cancer aggressiveness (no metastatic process), Informed consent (signed). Each patient underwent an initial nephrological and nutritional evaluation during which a conventional CKD Mediterranean-like diet with a controlled protein intake (MCPD) (0.6-1 g total protein/kg body weight/die and 30-35 kcal/kg body weight/die) was prescribed together with physical activity recommendation according to The National Kidney Foundation (NKF) for a period of 6 months (±2 months). Physical activity recommendations included some aerobic exercise for 30 min on most days of the week, plus other activities to increase muscle strength (exercises with resistance bands) e/o to improve flexibility (such as stretching) once or twice a week. To assess the influence of physical activity within the collaborative nephrologist-nutritionist approach (NNCA) on enhanced kidney function, the Rapid Assessment of Physical Activity (RAPA) test was administered to each patient. The test consists of two indicators: RAPA 1 will indicate aerobic physical activity levels (from 0=sedentary to 7=physically active), while RAPA 2 will indicate other types of exercises (0=none; 1=strength; 2=flexibility; 3=both). Subsequently, Bioelectrical Impedance Analysis (BIA) was conducted on all participants in the cohort to collect data on Body Cell Mass per height squared (BCM/h2), Phase Angle (PA), Extracellular Mass (ECM)/BCM, and Extracellular to Intracellular water ratio (ECW/ICW). Statistical analysis: Linear regression and Pearson's Chi-Squared test; Data analysis: R programming language and RStudio integrated development environment. Results Table 1 shows the patient's baseline characteristics. Table 2 shows anthropometric indices and parameters at pre- and post-dietary and nephrological intervention. Table 3 underlines the poor condition prevalent in CKD patients with or without oncological history, also confirmed by the low level of usual physical activity detected by the RAPA test at T0. Sure enough, our population was mainly inactive and sedentary. Results show that, after the intervention, our patients became regularly active (RAPA 1 score T0: 2.47; RAPA 1 score T1: 3.17; Delta = + 0.7, p &amp;lt; 0.0001); the same trend was observed for RAPA 2 score (observed increase 14%, p &amp;lt; 0.002). Conclusion Based on these findings, it can be inferred that standard clinical care should incorporate thorough assessment of both nutritional status and PA. The adoption of a MCPD, coupled with exercise training within a collaborative nephrologist-nutritionist approach, emerges as a potential strategy to enhance the HRQoL of this particular kind of patient.

#670 Clinical characteristics of sarcopenic obesity in hemodialysis patients

Abstract Background and Aims Sarcopenia is associated with all-cause mortality in older dialysis patients. Although obesity is a risk factor for a variety of diseases in the general population, obese hemodialysis patients have a survival advantage over lean patients. Some hemodialysis patients are obese but have reduced muscle mass, a condition known as sarcopenic obesity. The characteristics and diagnostic criteria for sarcopenic obesity in dialysis patients remain unclear. This study aims to determine the prevalence and clinical characteristics of patients at risk for sarcopenia or sarcopenic obesity. Method The dialysis centers involved in this study were four dialysis centers belonging to Seiei-kai Medical Corporation. Hemodialysis patients attending these facilities were included. Obesity was defined as a BMI of 25 kg/m2 or higher, and sarcopenia risk was described as a SARC-F questionnaire score of 4 or higher and a sit-to-stand test (SS-5) of 12 seconds or longer. Patients were classified as sarcopenic obese if they met both criteria. Patients classified as obese (OB) or sarcopenic obesity (SO) were compared for the following factors: age, history of dialysis, sex ratio, presence of diabetes, blood biochemical tests, Kt/V, nPCR, %CGR, number of falls in the past year, and symptoms using the Patients Reported Outcomes Measure (PROM). Results We analyzed the cross-sectional data of 622 patients attending our four dialysis centers. The prevalence of SO among all patients was 6% (34 patients), and OB was 26% (164 patients); Hb (10.9 ± 1.5 vs. 11.4 ± 1.2 g/dl; p=0.03), albumin (3.40 ± 0.3 vs. 3.63 ± 0.3 mg/dl; p&amp;lt;0.01) and nPCR (0.82 ± 0.16 vs. 0.91 ± 0.13 g/kg/day; p=0.01) were significantly lower in the SO group than in the OB group. Age (72.4 ± 9.2 vs. 32.9 ± 12.7 years; p&amp;lt;0.01) was higher in the SO group, and patients with a history of falls were significantly more likely to be in the SO group (59% vs. 29%; p&amp;lt;0.01). Symptom severity as measured by the PROM was also higher in the SO group. Conclusion This study showed that patients in the SO group were more likely to fall and had inadequate protein intake. In addition, patients in the SO group are older and have more severe PROM symptoms. Interventions to increase muscle strength and improve physical function should be considered for patients with SO. Nutritional support, treatment of individual symptoms, and exercise therapy will be necessary, and these interventions may be complex and challenging. We will design an observational study on the prognostic impact of sarcopenic obesity. A limitation of this study is that we used the SARC-F questionnaire and SS-5 rather than the AWGS criteria to assess sarcopenia, which may not have captured true sarcopenia.

The Clinical Management of Electrical Stimulation Therapies in the Rehabilitation of Individuals with Spinal Cord Injuries.

Background: People with spinal cord injuries (SCIs) often have trouble remaining active because of paralysis. In the past, exercise recommendations focused on the non-paralyzed muscles in the arms, which provides limited benefits. However, recent studies show that electrical stimulation can help engage the paralyzed extremities, expanding the available muscle mass for exercise. Methods: The authors provide an evidence-based approach using expertise from diverse fields, supplemented by evidence from key studies toward the management of electrical stimulation therapies in individuals with SCIs. Literature searches were performed separately using the PubMed, Medline, and Google Scholar search engines. The keywords used for the searches included functional electrical stimulation cycling, hybrid cycling, neuromuscular electrical stimulation exercise, spinal cord injury, cardiovascular health, metabolic health, muscle strength, muscle mass, bone mass, upper limb treatment, diagnostic and prognostic use of functional electrical stimulation, tetraplegic hands, and hand deformities after SCI. The authors recently presented this information in a workshop at a major rehabilitation conference. Additional information beyond what was presented at the workshop was added for the writing of this paper. Results: Functional electrical stimulation (FES) cycling can improve aerobic fitness and reduce the risk of cardiovascular and metabolic diseases. The evidence indicates that while both FES leg cycling and neuromuscular electrical stimulation (NMES) resistance training can increase muscle strength and mass, NMES resistance training has been shown to be more effective for producing muscle hypertrophy in individual muscle groups. The response to the electrical stimulation of muscles can also help in the diagnosis and prognosis of hand dysfunction after tetraplegia. Conclusions: Electrical stimulation activities are safe and effective methods for exercise and testing for motor neuron lesions in individuals with SCIs and other paralytic or paretic conditions. They should be considered part of a comprehensive rehabilitation program in diagnosing, prognosing, and treating individuals with SCIs to improve function, physical activity, and overall health.

Advances in SARMs anti-doping analysis.

Selective androgen receptor modulators (SARMs) are performance-enhancing drugs (PEDs) that stimulate anabolism, increase muscle mass and strength and promote recovery from exercise. The use of SARMs in sports is considered doping and is strictly prohibited by the World Anti-Doping Agency (WADA) and the International Federation of Horseracing Authorities (IFHA). To monitor the abuse of SARMs in sports, it is essential to develop advanced, selective and sensitive analytical methods that provide reliable results. This review evaluates the advances in this area, with a focus on the identification of target analytes related to SARMs, such as SARMs, their metabolites or markers. The aim is to identify targets that could extend the detection windows of SARMs, provide scientific support for results management and/or offer an indirect biomarker-based approach to doping control. This review also aims to evaluate the current liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods developed for the monitoring of SARMs in different biological matrices, including traditional matrices such as urine and serum/plasma samples, as well as alternative matrices such as dried blood spots, hair and nail samples.

The Effect of Infrared (IR) and Mirror Exercise on Increasing Muscle Strength and Functional Ability in Bell's Palsy Cases

Bell's Palsy is an acute, ipsilateral facial nerve (VII) paralysis. Bell's palsy is alsocaused by swelling and pressure on the nerve in the stylomastoid foramen whichcauses damage to the facial nerve. Problems that sufferers often experience after realizing facial muscle weakness from a physiotherapy perspective include facial asymmetry, a feeling of stiffness and thickness on the affected side of the face and decreased facial muscles. force on the affected side has the potential for spasm and tissue adhesions, as well as potential irritation to the affected side of the eye. The population of this study consisted of 30 respondents. Special examination for Bell's palsy sufferers using the Ugo Fisch scale and a treatment program using infrared (IR) and mirror exercise methods. This action aims to increase facial muscle strength, reduce muscle spasm, increase functional activity of facial muscles, and increase functional activity. The sample for this research consisted of 20 respondents. From the results of the hypothesis test, a p-value of 0.000 (alpha &lt; 0.05) is obtained as a critical limit, which means that H0 is rejected and Ha is accepted. So, the results of this therapy show a significant increase in facial muscle strength and functional ability between before and after therapy. Based on these results, the intervention given in the form of infrared (IR) and mirror exercise was effective in increasing muscle strength and functional ability as well as improving the participants' nerves.

INDIVIDUAL STRENGTH CHANGES FOLLOWING A VERY BRIEF INTERVENTION ON NATIONAL STRENGTH TRAINING GUIDELINES IN ADULTS AGED 50 - 75 YEARS

BACKGROUND There is little evidence that the public or healthcare practitioners are aware of and implementing the strength training component of the United Kingdom’s (UK) Chief Medical Officers’ physical activity guidelines in practice. Our study aimed to objectively measure strength following a very brief intervention with the strength component to determine if this practice could increase muscle strength. METHODS This was a mixed method, one-arm, pre-post six-month study. Thirty adults aged 50-75 years had hand grip (upper) isometric strength and ankle plantarflexion (lower) isometric strength measured. The average of two trials on the dominant limb were recorded. Participants were provided a physical copy of the guidelines and were asked to follow the strength recommendations. The very brief intervention (five minutes) included information on why and how to follow the strength guidelines, example exercises, along with a proven behaviour change technique (providing a journal to record training sessions). Strength was tested after six-months. RESULTS The group average indicated that there was no change in upper or lower body strength from baseline. However, when data were viewed individually, upper body strength was gained in 21 of 30 participants and lost in 9 (range: -4.5 to +6 kg). 42% of participants gained more than 2 kg in hand strength after six-months. Lower body strength was gained in 15 participants and lost in 15 (range: -12.4 to +8.65 kg). 43% of participants lost more than 2 kg. Qualitatively participants took the opportunity to ‘procure some new weights’ as they found their weights at home ‘too easy.’ Participants had a new-found realisation that ‘strength training is vital to muscle strength.’ Some mentioned that ‘strength training is now part of my life.’ On the other hand, other participants wanted more, noting that ‘there should be more publicity, information about [strength training] to the general public’ and found it unnecessarily ‘hard to find [follow up information] online.’ CONCLUSIONS In the movement to make ‘every contact count,’ a very brief intervention has been shown to raise awareness and change strength training behaviour. Healthcare practitioners should focus on lower body exercise examples alongside progression techniques to avoid rapid loss in lower body strength. Public health stakeholders need to work together to provide easily accessible strength training resources.

Functional and Combined Training Promote Body Recomposition and Lower Limb Strength in Postmenopausal Women: A Randomized Clinical Trial and a Time Course Analysis.

Encouraging healthy aging in postmenopausal women involves advocating for lifestyle modifications, including regular physical exercise like combined training (CT) and functional training (FT). Regarding this population, age-related alterations in body composition, such as decreased muscle mass and heightened adipose tissue, impact health. The aim of this study was to analyze the effects of FT and CT on body recomposition in postmenopausal women. About the methods, we randomly allocated 96 post-menopausal women to the FT, CT, or control group (CG). We measured body composition by bioimpedance and lower limb muscle strength by sit-to-stand test in five repetitions, respectively. The training protocol lasted 16 weeks, and we measured body composition and lower limb muscle strength every 4 weeks, totaling five assessments. Regarding results, we notice that both training groups increased lean mass from the 8th week of training. In addition, a reduction was observed in total fat percentage and an increase in appendicular lean mass from the 12th week of intervention. No differences were found for body mass. Furthermore, only the experimental groups increase muscle strength, starting from the 4th week of training. The conclusion was that FT and CT promote similar adaptations in body recomposition without affecting body mass in postmenopausal women.