The key position of grain farming and livestock in the South of Russia in the economic sphere is due to the fact that it can be the main factor in ensuring food security and the main condition for the sustainable development of agriculture and the agro-industrial sector as a means of using soil, climatic, orographic and conditions of the land use effectively. These factors make it possible to consider an increase in grain and livestock production for the market a strategic task for the region, and first of all, as an indicator of the most efficient use of the natural resource potential of the territory. An analytical study is conducted on the database management of two multi-parameter systems, the environment and the crop and livestock production state on the basis of reports and statistical materials. The analysis of the current industries state is aimed at identifying decision-making methods for managing agricultural land productivity based on agro-ecological and landscape zoning of the territory of an agribusiness. Currently, there are conditions when it is necessary to switch to a new scientifically based model of the spatial business organization. This will allow implementing the strategy of environmentally adaptive intensification of crop and livestock production. This approach is based on the identification of seven agro-ecological groups of lands and the placement of field, forage and soil-protection crop rotations on them, taking into account the proposed model of the soil-protective complex, reducing the manifestation of water and wind erosion. Such an approach in the use of the territory of an agribusiness will correspond to the grain and livestock specialization of the third agricultural zone of the Stavropol region.