A theoretical and experimental study of the forced frequency response of a two-degree-of-freedom system with dynamic dry friction is presented. Account is taken of the interface characteristics responsible for the changes of the system natural frequencies and the modification of the damping during frictional contact. The interface characteristics are represented by the equivalent dynamic tangential contact stiffness and by the equivalent viscous friction damping that are generated between the contacting surfaces. A new mathematical model describing the dynamic response of a frictionally constrained system under the influence of a normal load is developed. Experimental verification of the results obtained is presented to establish the validity of this model for explaining the vibratory regimes generated (elastic sticking, micro- and macro-sliding). The evolution of both the contact stiffness and the damping coefficient with the excitation frequency, tangential excitation force and the applied normal load, is described. As a result, it is shown that both the damping coefficient and the equivalent dynamic tangential contact stiffness increase with increasing applied normal load.