There is a steady and concentrated effort to improve finite element models of the spinal motion segment that can simulate various clinical situations accurately. Recent developments in the area of poro-elastic finite element models including fluid structure interaction with in the disc have made it possible to understand the relationship between disc failure mechanisms and time dependent loading. The development of such a finite element model is presented here and used to predict the failure progression in a lumbar disc due to a physiologically relevant cyclic loading. This will help to understand how repetitive lifting is of importance in the development of back injuries.