Incident Frequency Research Articles

Real-world diagnostic landscape and incidence of pulmonary hypertension in adult congenital heart disease patients using administrative claims data in Japan

Background Although pulmonary hypertension (PH) and Eisenmenger’s syndrome (ES) are common complications in adult congenital heart disease (ACHD), the frequency of diagnostic tests and the incidence of PH/ES in patients with ACHD in Japanese clinical practice are unclear. Therefore, we sought to clarify the frequency of diagnostic tests and incidence of PH/ES in patients with ACHD using the Medical Data Vision (MDV) database, the largest anonymized database of diagnosis procedure combination hospitals in Japan. Methods We conducted a retrospective cohort study using the MDV database (April 2008 to December 2021) of patients with ACHD (International Classificaiton of Diseases, 10th revision codes: Q203-204, Q210-213, Q250) aged ≥15 years. The frequency of laboratory/clinical tests and the incidence of PH/ES were calculated. Subgroup analyses were performed for the periods 2008–2015 and 2016–2021. Results Overall, 28219 ACHD patients were extracted from the MDV database (females 56.3%, males 43.7%; mean ± standard deviation age 44.7 ± 23.5 years). The mean ± standard deviation follow-up period was 2.5 ± 2.7 years. The frequencies of electrocardiography, ultrasonography, brain natriuretic peptide (BNP), N-terminal pro-BNP (NT-proBNP), right heart catheterization, and pulmonary function tests (DLCO) were 2149.8, 1054, 1233, 340, 40.0, and 6.0 per 1000 person-years, respectively. The incidence rate of PH/ES was 32.8 per 1000 person-years. The incidence rate of PH/ES increased from 24.6 to 46.7 per 1000 person-years from 2008–2015 to 2016–2021. Conclusion We have clarified the frequency of diagnostic tests related to PH/ES and the incidence of PH/ES in patients with ACHD in clinical practice in Japan, including non-specialist institutions for PH.

The Life Cycle of a Code White: A Framework for Managing Workplace Violence

A global challenge affecting health care organizations in the Covid-19 pandemic recovery era has been an increase in the incident frequency as well as qualitative severity and complexity of workplace violence (WPV) incidents. In Ontario, Canada, WPV in health care settings is often managed using an emergency response procedure known as a Code White (CW). The Toronto-based University Health Network (UHN) — a research and teaching hospital network with four centers of care and about 18,000 employees (including about 1,200 physicians and 3,900 registered nurses), a learning institute serving about 17,500 learners, and a research team with about 1,150 principal investigators — has engaged in a comprehensive quality improvement (QI) framework with the view to fully understand the complexity of CWs and effectively implement and evaluate complex interventions required to address the multidimensional problem of WPV. As part of this effort, UHN has developed the Life Cycle of a Code White (LCCW) by leveraging principles of System Engineering Initiative for Patient Safety 101, including the application of a journey map to outline the steps and involvement of specific functional units in CW incidents. This task necessitated extensive engagement with diverse stakeholders across the organization. The authors provide an example of how the LCCW initiative can be applied to enable the organization to operationalize the complexity of CW QI, catalyzing the formation of a formal CW governance structure, 12 distinct QI initiatives, and 17 quality indicators to inform data-driven change management.

A Statewide Evaluation of the Implementation of Evidence-Based Suicide Prevention Guidelines in Juvenile Detention Centers.

This study aimed to explore suicide prevention in juvenile detention centers by conducting a case study of one state. Qualitative data from semistructured interviews were synthesized from 10 juvenile detention centers. Analytical techniques included thematic and content analysis and the integration of quantitative information and qualitative themes to illustrate key differences in suicide prevention practices and center characteristics among facilities with varying frequencies of crisis stabilization calls and critical incidents. Although the use of many suicide prevention practices was reported across the sample, the quality with which those practices were implemented was highly variable. The analysis suggests that facilities with higher-quality implementation of suicide prevention practices may have had leaders who acknowledged that their facility plays a role in suicide prevention. Moreover, preliminary evidence suggests that the quality of suicide prevention implementation may be associated with the number of crisis stabilization calls and critical incidents (i.e., variables related to suicidality) a facility experiences. Clear conceptualization of a juvenile detention center's role in suicide prevention may lead to better outcomes in suicide prevention implementation. High-quality implementation may reduce suicidality exhibited by youths in juvenile detention and save lives.

Measurement of nonlinear three-wave interaction using shear-vertical-wave point-focusing electromagnetic acoustic transducers

Abstract We developed a method of nonlinear three-wave interaction using shear-vertical-wave point-focusing electromagnetic acoustic transducers (SV-wave PF-EMATs). EMATs can excite and detect ultrasonic waves without couplants through interaction between electromagnetic fields and solid mechanics and are generally unsuitable for the nonlinear ultrasound measurement due to their low signal conversion efficiency. However, our originally developed PF-EMAT can focus SV waves at a focal point in phase, achieving a large local displacement. Here, two PF-EMATs with different driving frequencies are placed facing each other so as to match their focal points, where the focused SV waves intersect to induce the third waves with the frequencies of the sum and difference of the incident frequencies through the nonlinear three-wave interaction. We demonstrate that the local nonlinearity can be measured by this method with EMATs and demonstrate its applicability to evaluation of fatigue damage in a fatigue crack initiation phase with aluminum alloy specimens.

Model for Technology Risk Assessment in Commercial Banks

As the complexity of banking technology systems increases, the prevention of technological risk becomes an endless battle. Currently, most banks rely on the experience and subjective judgement of experts and employees to allocate resources for technological risk management, which does not effectively reduce the frequency of technology-related incidents. Through an analysis of mainstream risk management models, this study proposes a technology-based risk assessment system based on machine learning. It first identifies risk factors in bank IT, preprocesses the sample data, and uses different regression prediction models to train the processed data to build an intelligent assessment model. The experimental results indicated that the Genetic Algorithm–Backpropagation Neural Network model achieved the best performance. Based on assessment indicators, indicator weight values, and risk levels, commercial banks can develop targeted prevention and control measures by applying limited resources to the most critical corrective actions, thereby effectively reducing the frequency of technology-related incidents.

Effective wave velocity in rock masses with double-scale discontinuities under in-situ stresses

The effective velocity of stress wave in rock masses with double-scale discontinuities subjected to in-situ stresses was investigated in the present study. An improved model that comprehensively considers the deformation of macrojoint and wave velocity of microdefected rock mass under in-situ stress was proposed to study the effective velocity of stress wave. The effect of in-situ stress on effective velocity was systematically analyzed using the presented model. The effect of the propagation distance, incident wave amplitude and incident wave frequency on effective velocity under in-situ stresses were further discussed and compared with the results of traditional study that disregards the influence of in-situ stress. The findings demonstrate that the small in-situ stresses have a substantial effect on the effective velocity. The effective velocity shows a trend of rapid increase followed by slow increase as increases of in-situ stress. Additionally, the effective velocity increases with propagation distance and amplitude. In the low and high-frequency regions, the effective velocity remains approximately at minimum and maximum values. A significant increase in the effective velocity is observed as the frequency increases in the mid-frequency region. However, it is noted that the effective velocity does not change significantly with increasing amplitude for sufficiently large in-situ stresses, and the influence of amplitude on the effective velocity can be disregarded. Furthermore, it is found that the effective velocity resulting from the present study is consistently larger than that resulting from the traditional study due to the effect of the in-situ stress. The findings of this investigation offer useful theoretical guidance for research into the effective velocity in deep rock mass.

Genomic Variants and Worldwide Epidemiology of Breast Cancer: A Genome-Wide Association Studies Correlation Analysis.

Breast cancer (BCa) is the most common cancer and leading cause of cancer death among women globally. This can be explained by the genetic factor of this disease. This article aims to correlate the epidemiological data, worldwide incidence, and mortality of BCa with the Single-Nucleotide Polymorphisms (SNPs) associated with the susceptibility and severity in different populations. Two hundred and forty genetic variants associated with BCa susceptibility/severity were selected from the literature through Genome-Wide Association Studies (GWAS). The allele frequencies were obtained from the 1000 Genomes Project, and the epidemiological data were obtained from the World Health Organization (WHO). The BCa incidence, mortality rates, and allele frequencies of the variants were evaluated using Pearson's correlation. Our study demonstrated that 11 SNPs (rs3817578, rs4843437, rs3754934, rs61764370, rs780092, rs2290203, rs10411161, rs6001930, rs16886165, rs8051542 and rs4973768) were significantly correlated with the epidemiological data in different ethnic groups. Seven polymorphisms (rs3817578, rs3754934, rs780092, rs2290203, rs10411161, rs6001930 and rs16886165) were inversely correlated with the incidence rate and four polymorphisms (rs4843437, rs61764370, rs8051542 and rs4973768) were directly correlated with the incidence rate. African and South-East Asian populations have a lower risk of developing BCa when evaluated in terms of genetic factors since they possess variants characterized as protective, as their higher incidence is associated with a lower frequency of BCa cases. The genetic variants investigated here are likely to predispose individuals to BCa. The genetic study described here is promising for implementing personalized strategies to screen for breast cancer in diverse populations.

Theoretical modeling of a co-located system with a floating wind platform and vertical truncated cylinders array

Combined floating offshore wind turbines (FOWTs), wave energy converters (WECs), and floating solar photovoltaics (FPVs) systems have the potential to provide cost-effective solutions for offshore multi-energy complementation and structure protection. In this study, a theoretical model based on the potential flow theory and eigenfunction matching method is utilized to study wave diffraction and radiation by a co-located system, in which the main components of the wind platform and WECs are made of vertical cylindrical floats. Based on the displacement constraint matrix, coupled equations of motion are developed to calculate the kinematic response of the co-located systems. After running the convergence analysis and model validation, the present model is employed to perform a multiparameter impact analysis. Case studies are presented to clarify the effects of the WEC radius, draft, layout, power take-off (PTO) system, and incident wave heading and frequency on the hydrodynamic coefficient, wave energy capture width, and motion response of the wind platform. Our findings highlight that several factors play a crucial role in the performance of the co-located system, more importantly, that the theoretical model developed in this study is capable of effectively predicting the wave-structure interactions in wave fields, making it applicable to future wave farm projects.

Cyber insurance risk analysis framework considerations

PurposeIn recent years, the frequency and severity of cybersecurity incidents have prompted customers to seek out specialized insurance products. However, this has also presented insurers with operational challenges and increased costs. The assessment of risks for health systems and cyber–physical systems (CPS) necessitates a heightened degree of attention. The significant values of potential damages and claims request a solid insurance system, part of cyber-resilience. This research paper focuses on the emerging cyber insurance market that is currently in the process of standardizing and improving its risk analysis concerning the potential insured entity.Design/methodology/approachThe authors' approach involves a quantitative analysis utilizing a Likert-style questionnaire designed to survey cyber insurance professionals. The authors' aim is to identify the current methods used in gathering information from potential clients, as well as the manner in which this information is analyzed by the insurers. Additionally, the authors gather insights on potential improvements that could be made to this process.FindingsThe study the authors elaborated it has a particularly important cyber and risk components for insurance area, because it addresses a “niche” area not yet proper addressed in specialized literature – cyber insurance. Cyber risk management approaches are not uniform at the international level, nor at the insurer level. Also, not all insurers can perform solid assessments, especially since their companies should first prove that they are fully compliant with international cyber security standards.Research limitations/implicationsThis research has concentrated on analyzing the current practices in terms of gathering information about the insured entity before issuing the cyber insurance policy, level of details concerning the cyber security posture of the insured entity and way such information should be analyzed in a standardized and useful manner. The novelty of this research resides in the analysis performed as detailed above and the proposals in terms of information gathered, depth of analysis and standardization of approach made. Future work on the topic can focus on the standardization process for analyzing cyber risk for insurance clients, to improve the proposal based also on historical elements and trends in the market. Thus, future research can further refine the standardization process to analyze in more depth the way this can be implemented and included in relevant legislation at the EU level.Practical implicationsProposed improvements include proposals in terms of the level of detail and the usefulness of an independent centralized approach for information gathering and analysis, especially given the re-insurance and brokerage activities. The authors also propose a common practical procedural approach in risk management, with the involvement of insurance companies and certification institutions of cyber security auditors.Originality/valueThe study investigates the information gathered by insurers from potential clients of cyber insurance and the way this is analyzed and updated for issuance of the insurance policy.

The investigation of joint stiffness determination based on the frequency characteristics of transmitted wave in rock mass

This study presents an investigation of joint stiffness determination by the frequency characteristics of transmitted wave in rock mass. First, the frequency characteristics of transmitted waves were investigated, and a method for determining joint stiffness based on frequency characteristics was proposed. Subsequently, the method was applied in a pendulum impact test to determine the joint stiffness of different joints. The stiffnesses of non-filled, sand-filled and clay-filled joints were determined. Finally, the effects of the amplitude and frequency of the incident wave on the accuracy of the joint stiffness determination method were discussed by comparing the predicted transmitted wave amplitude and energy with the measured transmitted wave amplitude and energy. The results show that the joint stiffness determination method can predict the transmitted wave amplitude and energy through a non-filled joint with more accuracy than a filled joint. In addition, for sand or clay-filled joints, the present method could satisfactorily predict the transmitted wave amplitude at a lower incident amplitude and a higher incident frequency. In contrast, when predicting the transmitted wave energy, a lower incident amplitude and frequency were more suitable.

Computational investigation of the interaction mechanisms of low‐density polyethylene (LDPE)/polyurethane and low‐density polyethylene (LDPE)/hexane systems as absorbents for oil spill remediation: A DFT study

AbstractThe escalating frequency of oil spill incidents and industrial wastewater discharges necessitates the development of effective remediation strategies. In this study, we conduct a comprehensive computational investigation using density functional theory (DFT) to elucidate the interaction mechanisms within polyethylene (PE) combined with polyurethane (PU) and hexane. The study focuses on adsorption energies, intermolecular interactions, miscibility, and electronic properties, providing a molecular‐level understanding crucial for designing advanced absorbent materials. The investigation reveals that the low‐density polyethylene/polyurethane (LDPE/PU) system exhibits significantly higher adsorption energies (−12.87 kcal/mol) compared to PE/hexane (−7.66 kcal/mol), indicating a robust binding affinity. This discrepancy underscores the superior performance of PE/PU as an absorbent material. The enthalpy results, with ∆H values of −55.75 kcal/mol for PE/hexane‐n‐hexadecane and −66.11 kcal/mol for PE/PU‐n‐hexadecane complexes at 298.15 K, support exothermic adsorption. The more exothermic ∆H for PE/PU indicates stronger interactions during oil absorption than PE/hexane. Additionally, Gibbs free energy change (∆G) values affirm a more favorable process for PE/PU, exhibiting a lower ∆G (−42.54 kcal/mol) compared to PE/hexane (−34.79 kcal/mol). Non‐covalent interaction (NCI) studies confirm the importance of van der Waals forces in both systems, validating their role in the adsorption process. Miscibility studies indicate limited interactions, with PE/PU showing positive enthalpy of mixing. Electronic study demonstrates PE/PU's higher energy gap of 9.19 eV, correlating with superior performance. This research contributes to the fundamental understanding of oil absorption processes and informs the design and optimization of environmentally sustainable and efficient oil‐absorbing materials for remediation applications.Highlights DFT explores polymeric systems, PE/PU and PE/hexane, for oil absorbent. PE/PU excels with −12.87 kcal/mol adsorption energy, surpassing PE/hexane (−7.66 kcal/mol). NCI validates van der Waals forces in both systems, crucial for effective adsorption. Miscibility studies reveal limited interactions. PE/PU's superior 9.19 eV energy gap signifies enhanced absorbent performance. PE/PU excels as an oil‐absorbent material, underlining its overall superiority.

Vertical seismic response of end-bearing piles in nearly saturated soil

This paper presents a study on the effect of the degree of saturation of the foundation soil on the vertical seismic response of end-bearing piles subjected to P-waves. The research focuses on nearly saturated soil, where the air phase is not continuous and air bubbles are dissolved in the pore water, and thus can be treated as two-phase material. The response of the two-phase soil–pile system is quantified by means of a rigorous coupled hydromechanical model, which is based on Biot’s theory for poroelastic media and treats the air bubbles–pore water mixture as a homogeneous fluid obeying Boyle’s law. Numerical results are used to illustrate the influence of the degree of saturation of the soil layer on the seismic strong motion transferred to the pile head, i.e., the capacity of piles to filter seismic wave energy. This work bridges the gap between single-phase and two-phase saturated soil models, which predict profoundly different pile head displacements at incident wave frequencies of practical interest, and elucidates the mechanisms that lead to these differences.

Room temperature AC electrical, surface micro texture analysis, microwave permittivity and dielectric loss tangent in ZnO films doped by Cu, Al, and CuAl

The purpose of this work is the study of the correlation between the thickness of ZnO films doped by transition metals and their three-dimensional (3D) micromorphology. The as deposited ZnO films became more irregular surface hence the maximum value of Sq belong to as deposited ZnO films was in a bout of 0.1038 mm. The core roughness height Sk calculated as a difference between two extreme levels (maximal and minimal) of surface core, for ZnO films annealed at 500 °C have maximum value in a bout of 0.7325 mm. Since the surface kurtosis (Sku) of all sample's films were above 7, therefore there were high peaks or valleys on the films surface and for as deposited CAZO films with value of with 8.883. The height distribution histograms shown that as deposited films respect to annealed films have more uniform distributions. The AZO films annealed at 500 °C have maximum value of DC conductivity in about 104.167 S cm−1. The value of log (dielectric loss tan(δ)) in AZO films have maximum value in range 0.05–0.15. As the frequency of incident photons were increased the polarization orientation were increased. Log AC conductivity values of films were shown almost linear behavior with increasing incident photons frequency that indicates conduction hopping is followed by a small polaron mechanism. AC conductivity values of as deposited AZO films in all frequencies have maximum value.

Nurses' perceptions about the patient safety climate in Primary Health Care.

to evaluate the patient safety climate in Primary Health Care from the perspective of nurses working in the services. a quantitative and cross-sectional study conducted with 148 nurses from a municipality in the state of São Paulo. The Brazilian version of the Primary Care Safety Questionnaire Survey and personal, professional, and organizational performance variables (intention to stay at work, job satisfaction, care quality, and frequency of incidents) were used. Parametric and non-parametric comparison tests and Spearman's correlation coefficient were performed, considering a 5% significance level. the safety climate was positive, varying from 4.52 to 5.33 and differing across districts for workload (p=0.0214) and leadership (p=0.0129). The safety climate professional variables and dimensions differed in relation to the frequency of incidents. Teamwork and safety and learning system were strongly correlated with job satisfaction and moderately with perceived care quality. teamwork and safety and learning system stood out for their positive correlations with job satisfaction and care quality. A positive safety climate favors the involvement of Primary Care nurses to develop improvement plans aligned with the National Patient Safety Program. (1) The safety climate is perceived differently across health districts. (2) There is a correlation between the climate dimensions and professional satisfaction. (3) Workload and leadership exert an influence on the safety climate perception. (4) There is a relationship between the safety climate and reporting of care-related incidents. (5) The safety climate is perceived differently among nurses regarding their role.

ШЛЯХИ ЗМЕНШЕННЯ ПОХИБОК ВИМІРЮВАННЯ ДІЕЛЕКТРИЧНОЇ ПРОНИКНОСТІ СЛАБОПОГЛИНАЮЧИХ ДІЕЛЕКТРИКІВ У МІЛІМЕТРОВОМУ ТА СУБМІЛІМЕТРОВОМУ (ТЕРАГЕРЦОВОМУ) ДІАПАЗОНАХ ДОВЖИН ХВИЛЬ МЕТОДОМ ПОВЕРХНЕВОГО ПЛАЗМОННОГО РЕЗОНАНСУ

Subject and Purpose. The sources of errors are identified that may arise in the course of terahertz-range measurements of the dielec- tric constant of weakly absorbent dielectrics, if performed within the surface plasmon resonance (SPR) technique. Possible ways are analyzed for reducing or fully eliminating such errors. Methods and Methodology. Specific details of applying the SPR method for dielectric constant measurements have been analyzed, with the aim of identifying the major factors that particularly affect the measurement accuracy. Results. It has been noted that in order to reduce the level of backlight interference (which may lead to blinding the receiver), it is expedient to make surface resonance records via frequency scanning. In that case the impact of the interference signal nonstationa- rity arising from the partial conversion of the surface wave energy into that of the volume wave, which occurs at the grating edges, is markedly lower than in the case of angular scanning. A mathematical expression has been derived which suggests a relation between scanning step sizes in angle and in frequency (for the angular and frequency scanning, respectively). As has been shown, a better mea- surement accuracy is achievable if the SPR is recorded as a function of frequency. Indeed, the frequency can be varied, with the use of familiar technologies, in steps of a much smaller size than such adopted for angular scanning. Errors in the above measurements can also arise if the resonance is excited on a grating whose Fourier spectrum contains many high-frequency components which carry a noticeable portion of the diffracted radiation energy. These energy losses can be greatly reduced if the SPR is excited on a grating whose profile involves the lowest number of spatial Fourier harmonics. Conclusions. The method suggested allows a significant reduction in the level of errors of the dielectric constant measurements in weakly absorbing dielectrics if the surface plasmon resonance effects are registered in dependence on the incident frequency, while the SPR is excited at a diffraction grating whose troughs-and-peaks profile is close to harmonical.

Addressing the health human resources crisis: Strategies for retaining women health care professionals in organizations.

Globally, healthcare systems are contending with a pronounced health human resource crisis marked by elevated rates of burnout, heightened job transitions, and an escalating demand for the limited supply of the existing health workforce. This crisis detrimentally affects the quality of patient care, contributing to long wait times, decreased patient satisfaction, and a heightened frequency of patient safety incidents and medical errors. In response to the heightened demand, healthcare organizations are proactively exploring solutions to retain their workforce. With women comprising over 70% of health human resources, this study seeks to gain insight into the unique experiences of women health professionals on the frontlines of healthcare and develop a conceptual framework aimed at facilitating organizations in effectively supporting the retention and advancement of women in healthcare frontline roles. We used grounded theory in this qualitative study. From January 2023 to May 2023, we conducted individual semi-structured interviews with 27 frontline HCWs working in Canada and representing diverse backgrounds. The data underwent thematic analysis, which involved identifying and comprehending recurring patterns across the information to elucidate emerging themes. Our analysis found that organizational, professional, and personal factors shape women's intentions to leave the frontline workforce. Reevaluating organizational strategies related to workforce, fostering a positive work culture, and building the capacity of management to create supportive work environment can collectively transform the work environment. By creating conditions that enable women to perform effectively and find satisfaction in their professional roles, organizations can enhance their ability to retain valuable talent.

The Issue of Man and Animal Conflict: A Case of Jhargram District, West Bengal

Man-animal conflict is an ancient concept in which humans and wild animals share the same landscapes and resources for their survival. The study investigates the increasing frequency of conflict incidents between humans and animals in various locations within Jhargram District, a region known for its close proximity to both human settlements and wildlife, particularly elephants. Currently, human-animal conflict plays a significant role in altering the landscapes of the southern region of West Bengal in India, and it also has an impact on the rural economy in Jhargram District. Human population growth and expansion, deforestation, habitat degradation, land use change, and livestock grazing in forest and forest fringe areas are all considered major causes of human-animal conflicts. The study aims to pinpoint the underlying causes and repercussions of human-animal conflicts, as well as suggest management strategies to address the issue. The study reveals that people living in forest fringe areas and close to forest protected areas are often prone to attacks, particularly by elephants and other wild animals like hyenas, wild dogs, wild boars, etc.

The Impact of COVID-19 Pandemic on Respiratory Syncytial Virus Infection in Children.

Background/Objective: Respiratory syncytial virus (RSV) is a major cause of bronchiolitis in infants and young children. Bronchiolitis, an acute inflammation of the lower respiratory tract, can lead to pneumonia, respiratory failure, and death. We aimed to compare the incidence and severity of RSV infection in children aged 0-60 months before and during the coronavirus disease 2019 (COVID-19) pandemic. Methods: A retrospective chart review was conducted on patients aged 0-60 months who tested positive for RSV between May 1, 2018, and May 31, 2022, in a community hospital in Queens County, New York City, United States. Comparisons were made between seasons 2018-2019 and 2019-2020 as before, and seasons 2020-2021 and 2021-2022 as during the COVID-19 pandemic. Severity of RSV infection was assessed using the Bronchiolitis Severity Score (BSS). Data were analyzed using R software, a p value of < 0.05 was considered statistically significant. Results: The incidence of RSV infection in seasons 2018-2019 and 2019-2020 peaked from mid-October to February, whereas the first season during the COVID-19 pandemic (2020-2021) was truncated with a very low incidence of RSV infection, and season 2021-2022 peaked from September to January, with the highest incidence (37%) and lower frequency of RSV infection at any given point. Patients during the season 2021-2022 were older (H [2, 196.6] = 12.5, p < 0.001, 95% CI = [5.4, 25.6]) and had milder illness (H [2, 187.5] = 7.5, p < 0.01, 95% CI = [2.1, 19.2]). Conclusions: We observed a lower incidence of RSV infection and a lower rate of hospitalization for RSV during the COVID-19 pandemic. The second RSV season during the COVID-19 pandemic began earlier, lasted longer, and had a lower frequency. Older children with milder illnesses were affected most during this season. RSV epidemiology and disease burden were impacted by the COVID-19 pandemic and could have significant ramifications for its prevention and control strategies.

Numerical prediction of the whistling potentiality of a turbulent channel flow with corrugated walls

This study explores the turbulent flow-induced whistling phenomena in a channel with corrugated wall surfaces, which is crucial for mitigating the acoustic fatigue problem in the aerospace field. By solving a compressible linearized Navier–Stokes equation in the frequency domain, the interference between the turbulent flow field along the corrugated wall and the incident acoustic field is studied, including the acoustic wave scattering phenomenon caused by turbulence and the fluid perturbation induced by acoustic waves. In conjunction with this, the acoustic two-ports method is utilized to investigate the transfer-function model and predict the whistling potentiality of the turbulent flow along corrugated walls. Experimental validations through the literature results confirm the numerical accuracy of this aeroacoustic simulation strategy. Subsequently, the investigation extends to different cavity configurations with different cavity profiles and numbers, and the two-port scattering matrix is applied to quantify the acoustic transmission and damping coefficients caused by the background flow field and turbulent eddy viscosity. The acoustic power conversion mechanism between the turbulent flow field and the incident acoustic field is established, allowing for quick prediction and effective analysis of the generation frequency range of the whistling phenomenon. Furthermore, the modulation effect of sound waves on the fluid is studied by analyzing the response of the incident sound wave frequency to the phase interference momentum and shear layer of different configurations of corrugated cavities. The results show that compared with the right-edge configuration, the rounded-edge configuration produces whistling at a lower frequency due to the turbulence effect, and the number of cavities adjusts the intensity, not the frequency, of the sound power generated. In addition, the oscillation of the shear layer caused by sound waves is related to the cavity configuration and the sound wave frequency.

Characterizing medication safety incidents in surgical patients: a retrospective cross-sectional analysis of incident reports.

Medication-related safety incidents (MSIs) are among the most frequent contributors to preventable harm in hospital patients. There is a paucity of research that explores the factors that contribute to MSIs across the departments of high-risk specialties such as surgery. To characterize MSIs involving surgical patients across two secondary care sites at a University Health Board. Retrospective cross-sectional convergent analysis of anonymous MSI reports extracted from the risk management system between 1st January 2017 and 31st October 2020 was undertaken. Incident reports contained categorical data pertaining to the type and nature of the incident as well as free-text reporter accounts. Categorical data were analyzed quantitatively, undergoing descriptive analysis using IBM SPSS Statistics © software (Version 26.0.01; 2019). Content analysis of free-text responses was undertaken using the Organizational Accident Causation model as the underpinning theoretical framework. Of a total of 670 incidents, most MSIs did not result in harm (n = 495, 73.9%). Most MSIs occurred during administration (n = 439, 65.5%). Half of the incidents (n = 335, 50%) were related to one of three medication types: opioids, antimicrobials, and antithrombotic agents. Communication failures were the most frequent error-producing condition (n = 39, 5.8%) and drug omission was the most frequent active failure (n = 156, 23.3%). To the knowledge of the authors, this is the first study in the United Kingdom that reports the medications most frequently involved in MSI reports for surgical patients. Staff in the surgical setting should be informed of the high frequency of incidents involving opioids, antimicrobials, heparin, and other antithrombotic agents as they appear in half of MSI reports in the surgical setting. Further research should explore administration error reduction strategies as well as tools to improve communication between staff to mitigate the risk of medicines-related harm associated with key medications.