Incidence Of Pulmonary Tuberculosis Research Articles

Ecological Studies of Climate Factors and Pulmonary Tuberculosis Cases in Padang City 2020-2023

Introduction: Tuberculosis (TB) is actually a disease that can be prevented and cured. In 2022, TB became the second leading cause of death in the world after Coronavirus (COVID-19), and caused twice as many deaths as HIV/AIDS. Several studies have stated that climate factors such as exposure to high temperatures, dry environments and exposure to ultraviolet light can influence the growth of Mycobacterium tuberculosis. Objective: This research aims to determine the distribution and correlation of climate factors with the number of pulmonary TB cases in Padang City in 2020-2023. Method: This research is an ecological study with the study population of Padang City. In this study the dependent variable is pulmonary TB cases and the independent variables are temperature, precipitation, and humidity. Pearson correlation is used to determine whether or not there is a relationship, the strength of the relationship, and the direction of the relationship between two normally distributed numerical variables. This research also describes descriptively the distribution of pulmonary TB cases in Padang City based on sub-districts using spatial analysis. Result: There is significant relationship in 2022 between temperature (p=0.010) and precipitation (p=0.019) with pulmonary TB cases in Padang City. However, there are no variables of climates related to pulmonary TB when analyzed cumulatively from 2020-2023. Based on the results of spatial analysis, it can be seen that Koto Tangah sub-district is consistently in the high category of pulmonary TB cases in 2020-2023. Conclusion: The research results found that temperature and precipitation in 2022 were significantly related with the incidence of pulmonary TB, while the humidity variable had no significant relationship with the incidence of pulmonary TB cases in Padang City. It is recommended to make climate factors such as one of the considerations in making policies related to the prevention of pulmonary TB.

Vitamin D Deficiency in Patients with Type 2 Diabetes Mellitus with and without Pulmonary Tuberculosis

Background: Vitamin D has a role in the body's calcium balance and immunodeficiency effects, and stimulates dendric cells, monocytes, T cells, macrophages in pathogenic microbes’ elimination. The variation occurrence as polymorphism on VDR might cause problem in production, transportation, and activity of vitamin D. The gap between the occurrence findings in previous studies shows that there are indication factors of VDR levels that probably associate with the T2DM range in comorbid with pulmonary tuberculosis. To determine vitamin D levels and factors associated with vitamin D deficiency in Type 2 Diabetes Mellitus (T2DM) patients with and without pulmonary Tuberculosis (TB). Method: The design of this study was cross-sectional. T2DM subjects with pulmonary TB were 45 people, and 43 people without pulmonary TB were 43 people. Sampling was done by consecutive sampling from October to December 2017. We collected data through interviews and examination of plasma vitamin D (25-OH) levels by ELISA. Data analysis using the Mann-Whitney test, and chi-square test with a confidence level of 95%. Result: There were 88 T2DM patients who met the inclusion criteria, consisting of 43 T2DM patients without pulmonary TB and 45 T2DM patients with pulmonary TB as the study subjects. There were differences in the distribution of T2DM subjects based on sex and BMI measurements. The mean plasma vitamin D levels in T2DM with pulmonary TB and T2DM without pulmonary TB were 20.08 ng/ml (SD ± 0.83 ng/ml) and 20.29 ng/ml (SD ± 0.81 ng/ml), respectively, we found no significant result in statistic (p = 0.287). Vitamin D deficiency was not associated with the incidence of pulmonary TB in T2DM, whereas female sex, age> 50 years, BMI ? 25.0 kg /m2, and duration of T2DM> 5 years were associated with vitamin D deficiency (p <0.05). This research has contributed in novel findings of the correlation between sex and BMI associated in duration of T2DM impacted the Vitamin D insufficiently. Conclusion: Sex, age, BMI, and duration of T2DM had a significant correlation with vitamin D deficiency in T2DM patients with and without pulmonary TB.

Influence of Temperature and Humidity on the Incidence of Pulmonary Tuberculosis in Hainan, China, 2004–2018

Influence of Temperature and Humidity on the Incidence of Pulmonary Tuberculosis in Hainan, China, 2004–2018

EXPOSURE TO THE PHYSICAL CONDITIONS OF THE HOME ENVIRONMENT WITH PULMONARY TB DISEASE IN KALUMATA VILLAGE

Background: Pulmonary TB is included in the ten highest disease categories yearly in almost all health centers in Ternate City, North Maluku. In certain age groups, pulmonary TB can be a cause of death. Environmental factors, especially the physical environment of the house, can be determinants of pulmonary TB disease. Purpose: This study aimed to determine the incidence of pulmonary TB if exposed to the physical environment of the house and the home environment. Methods: This research is observational with a case-control study design. She was held in the Coastal Area of ​​Kalumata Village, Ternate City. The number of samples in this study were all pulmonary TB sufferers. Data were collected from observations, interviews, and measurements to determine exposure to the physical environment of the house and the incidence of pulmonary TB. The chi-square test is used to determine the relationship between the variables studied. Results: The study's statistical results showed that all the variables did not significantly relate to the incidence of pulmonary tuberculosis associated with the physical condition of the house (p-value = 1.00 (> ɑ = 0.05). Conclusion: There is no relationship between the incidence of pulmonary TB and the house's physical condition.

TUBERCULOSIS PREVENTION BEHAVIOR AND RELATED FACTORS (STUDY AT NAIBONAT PRIMARY HEALTH CENTER, KUPANG REGENCY, 2023)

Background: Tuberculosis (TB) Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, which attacks the lungs and other organs. Purpose: To determine the relationship between the level of knowledge, attitudes, and preventive actions of Tuberculosis disease and TB incidence in the Naibonat Health Center working area 2023. Methods: The research design used was case-control by conducting analytical observations. Using a simple random sampling technique, the sample consisted of 41 cases and 41 controls. Data analysis used the chi-square test at a significance level of 95%. (α = 0.05). Results: Based on the research shows that there is a significant relationship between knowledge (p=0.00; OR=5.98), attitude (p=0.00; OR=4.66), TB prevention actions (p=0.01; OR=5.20) on the incidence of TB at the Naibonat Primary Health Center. Conclusion: The knowledge, attitudes, and preventive measures are significantly related to the incidence of pulmonary TB in the Naibonat Health Center working area. The community is expected to be able to pay attention to the environment where they live, have clean living behavior, and be able to participate in educational activities/socialization (counseling) related to Pulmonary TB conducted by health centers, NGOs, or health workers which help increase public knowledge.

Epidemiological and genetic aspects of pulmonary tuberculosis in Kazakhstan

ObjectiveTuberculosis is a major health problem in many countries, including Kazakhstan. Host genetics can affect TB risk, and epidemiological and social factors may contribute to disease progression. Due to the high incidence of pulmonary tuberculosis in the country, our research aimed to study the epidemiological and genetic aspects of pulmonary tuberculosis in Kazakhstan. Material and methods1026 participants of Central Asian origin were recruited in the study: 342 individuals diagnosed with active PTB, 342 household contacts, and 342 controls without a family history of TB. Genetic polymorphisms of selected genes were determined by real-time polymerase chain reaction. The association between the risk of pulmonary TB and polymorphisms was evaluated using logistic regression and assessed with the ORs and their corresponding 95 % CIs, and the significance level was determined as p < 0.05. ResultsEpidemiological data revealed that underweight BMI (χ² = 89.97, p < 0.001), employment (χ² = 39.28, p < 0.001), and diabetes (χ² = 12.38, p < 0.001) showed a significant association with PTB. A/T polymorphism of the IFG gene showed a lower risk, and A/A polymorphism showed an increased risk of susceptibility to TB. A/A polymorphism of the IFG gene was associated with an almost 3-fold increased risk of PTB, and A/T polymorphism of the IFG gene was associated with a decreased risk of PTB (OR = 0.67, 95 % CI = 0.49–0.92, p = 0.01). The analysis revealed a decreased risk of PTB for A/A polymorphism of the VDR ApaI (OR = 0.67, 95 % CI = 0.46–0.97, p < 0.05). A/A polymorphism of the TLR8 gene was associated with a 1.5-fold increased risk of PTB (OR = 1.53, 95 % CI = 1.00–2.33, p < 0.05). ConclusionResults showed that gender, employment, underweight BMI and diabetes are associated with PTB incidence in our study cohort. The A/A genotype of the IFG (rs2430561) and an A/A genotype of the TLR8 (rs3764880) genes were associated with an increased risk of PTB. A/T polymorphism of the IFG (rs2430561) and A/A polymorphism of the VDR ApaI were associated with a decreased risk of PTB.

Pengaruh Pemberian Promosi Kesehatan melalui Media Leaflet terhadap Pengetahuan Siswa/I tentang Pencegah Pencegahan TB Paru di SDN Sungai Lulut 8 Banjarmasin

Tuberculosis is an infectious disease caused by the Mycobacterium Tuberculosis germ, which mostly attacks the lungs. The problem of controlling pulmonary tuberculosis has been implemented in many countries since 1995, but it remains a health problem in the community that causes high mortality among infants, children, adolescents, and seniors. One of the government programs in controlling pulmonary tuberculosis is the Joint Movement against tuberculosis in education units, the targets in the program are students, teachers, and education personnel from kindergarten to senior high school by providing health promotion. Data collection conducted by researchers found a health center with the highest incidence of pulmonary TB in children in Banjarmasin city, there is one elementary school closest to the health center. This study aims to provide health promotion through leaflet media on students' knowledge about the prevention of pulmonary tuberculosis at SDN Sungai Lulut 8 Banjarmasin. This study used quantitative research Pre-experimental method with a one group pretest-posttest approach. The population in this study were 199 people. The sampling technique used was purposive sampling with a sample size of 67 students. This research instrument uses a questionnaire. The statistical test used is the Wilcoxon signed rank test. The results show that there is a difference between before and after giving promotion.

Faktor-Faktor yang Berhubungan dengan Kejadian TB Paru pada Anak di Poliklinik RSUD Embung Fatimah

Pulmonary TB in children is an infection caused by the germ Mycobacterium Tuberculosis. Pulmonary TB is transmitted from human to other human through the air when a BTA positive pulmonary TB sufferer talks, sneezes or coughs and indirectly the sufferer emits phlegm splashes in the air and there are ±3000 phlegm splashes containing germs. This research was conducted to determine the factors associated with the incidence of pulmonary TB in children at the Embung Fatimah Regional Hospital Polyclinic. The research method is descriptive with a cross sectional design. The sample consisted of 34 pediatric TB patients at the Embung Fatimah Regional Hospital Polyclinic using a sampling technique, namely total sampling. Data were processed using the chi square test. The results of this study show that there is no significant relationship between BCG immunization status and the incidence of pulmonary TB in children (P value of 0.450 &gt; 0.05), there is a significant relationship between contact with TB sufferers and the incidence of TB in children (P value of 0.021 &gt; 0.05), and there is a significant relationship between family smoking status and TB sufferers and the incidence of TB in children (P value of 0.014 &gt; 0.05). It is hoped that the role of nurses can overcome the problem of childhood TB through health promotion and increasing immunization coverage for children in the community.

Trend of pulmonary tuberculosis and rifampicin-resistance among tuberculosis presumptive patients in Central Tigray, Ethiopia; 2018 -2023: a six-year retrospective study

BackgroundTuberculosis (TB) is a major public health concern in the developing countries. Moreover, the emergence of multidrug-resistant tuberculosis is challenging. However, there are no organized data on the trends of pulmonary tuberculosis and rifampicin-resistant Mycobacterium tuberculosis in the study area.MethodsA retrospective cross-sectional study was conducted to fill the information gap in Central Tigray at St. Mary General Hospital between 2018 and 2023. Data were collected from the GeneXpert™ tuberculosis registration logbooks using standard checklists and analyzed using Statistical Package for Social Science version 22. After performing logistic regression, a p-value < 0.05 with a corresponding 95% confidence interval was considered statistically significant. Moreover, chi square test for trend was performed to assess the percentage of annual detection of pulmonary tuberculosis and rifampicin-resistant Mycobacterium tuberculosis during the study years.ResultPresumptive pulmonary tuberculosis patients with complete data (n = 3696) were included in the study. The overall prevalence of pulmonary tuberculosis was 11.7%, of which 8.1% were resistant to rifampicin. The study revealed that the incidence of pulmonary tuberculosis has been increasing, mainly in the recent four years. Likewise, an increase in rifampicin-resistant Mycobacterium tuberculosis was observed with considerable fluctuations. Age, human immunodeficiency virus infection, and presumptive rifampicin-resistant Mycobacterium tuberculosis infection were significantly associated with the presence of pulmonary tuberculosis. Moreover, pulmonary tuberculosis was more prevalent among participants in the productive-age group.ConclusionAlthough there have been fluctuations, an increasing of pulmonary tuberculosis and rifampicin-resistant Mycobacterium tuberculosis has been observed in recent years. Hence, prevention and treatment strategies for tuberculosis should be strengthened to alleviate the burden of pulmonary tuberculosis and rifampicin-resistant Mycobacterium tuberculosis in the study area.

Long-term exposure to ambient fine particulate matter (PM2.5) and attributable pulmonary tuberculosis notifications in Ningxia Hui Autonomous Region, China: a health impact assessment

IntroductionLong-term exposure to fine particulate matter (≤2.5 µm (PM2.5)) has been associated with pulmonary tuberculosis (TB) notifications or incidence in recent publications. Studies quantifying the relative contribution of long-term PM2.5...

Analysis of Nutritional Status and The Incidence of Pulmonary Tuberculosis in The Puskesmas Martapura 1

Tuberculosis (TB) is an infectious disease caused by bacteria and transmitted through the air. Indonesia, especially South Kalimantan, records a high number of TB cases. Martapura 1 Community Health Center, which is known for its significant number of pulmonary TB cases, requires special strategies in handling and prevention. This descriptive research uses a cross-sectional design. The research was carried out from February to June 2024, at Martapura 1 Health Center, Banjar Regency, South Kalimantan. The sample size was 50 people, with the sampling method being Accidental Sampling. Data collection techniques include BTA examination and BMI (Body Mass Index) assessment. Analysis of the relationship between nutritional status and the incidence of pulmonary TB in the working area of Martapura 1 Community Health Center, Banjar Regency, South Kalimantan based on statistical tests with chi-square obtained a p-value of 0.006 (p-value &lt;0.05). Therefore, it can be concluded that there is a relationship between nutritional status and the incidence of pulmonary TB in the working area of Martapura 1 Health Center, Banjar Regency, South Kalimantan in 2024. The incidence of pulmonary TB can affect a person's nutritional status.

Spatial-temporal distribution characteristics of pulmonary tuberculosis in eastern China from 2011 to 2021.

China is still among the 30 high-burden tuberculosis (TB) countries in the world. Few studies have described the spatial epidemiological characteristics of pulmonary TB (PTB) in Jiangsu Province. The registered incidence data of PTB patients in 95 counties of Jiangsu Province from 2011 to 2021 were collected from the Tuberculosis Management Information System. Three-dimensional spatial trends, spatial autocorrelation, and spatial-temporal scan analysis were conducted to explore the spatial clustering pattern of PTB. From 2011 to 2021, a total of 347,495 newly diagnosed PTB cases were registered. The registered incidence rate of PTB decreased from 49.78/100,000 in 2011 to 26.49/100,000 in 2021, exhibiting a steady downward trend (χ2=414.22, P<0.001). The average annual registered incidence rate of PTB was higher in the central and northern regions. Moran's I indices of the registered incidence of PTB were all >0 (P<0.05) except in 2016, indicating a positive spatial correlation overall. Local autocorrelation analysis showed that 'high-high' clusters were mainly distributed in northern Jiangsu, and 'low-low' clusters were mainly concentrated in southern Jiangsu. The results of this study assist in identifying settings and locations of high TB risk and inform policy-making for PTB control and prevention.

The potential association between metabolic disorders and pulmonary tuberculosis: a Mendelian randomization study

BackgroundMetabolic disorders (MetDs) have been demonstrated to be closely linked to numerous diseases. However, the precise association between MetDs and pulmonary tuberculosis (PTB) remains poorly understood.MethodSummary statistics for exposure and outcomes from genome-wide association studies (GWASs) for exposures and outcomes were obtained from the BioBank Japan Project (BBJ) Gene–exposure dataset. The 14 clinical factors were categorized into three groups: metabolic laboratory markers, blood pressure, and the MetS diagnostic factors. The causal relationship between metabolic factors and PTB were analyzed using two-sample Mendelian Randomization (MR). Additionally, the direct effects on the risk of PTB were investigated through multivariable MR. The primary method employed was the inverse variance-weighted (IVW) model. The sensitivity of this MR analysis was evaluated using MR-Egger regression and the MR-PRESSO global test.ResultsAccording to the two-sample MR, HDL-C, HbA1c, TP, and DM were positively correlated with the incidence of active TB. According to the multivariable MR, HDL-C (IVW: OR 2.798, 95% CI 1.484–5.274, P = 0.001), LDL (IVW: OR 4.027, 95% CI 1.140–14.219, P = 0.03) and TG (IVW: OR 2.548, 95% CI 1.269–5.115, P = 0.009) were positively correlated with the occurrence of PTB. TC (OR 0.131, 95% CI 0.028–0.607, P = 0.009) was negatively correlated with the occurrence of PTB. We selected BMI, DM, HDL-C, SBP, and TG as the diagnostic factors for metabolic syndrome. DM (IVW, OR 1.219, 95% CI 1.040–1.429 P = 0.014) and HDL-C (IVW, OR 1.380, 95% CI 1.035–1.841, P = 0.028) were directly correlated with the occurrence of PTB.ConclusionsThis MR study demonstrated that metabolic disorders, mainly hyperglycemia, and dyslipidemia, are associated with the incidence of active pulmonary tuberculosis.

Exploring the Impact of Socioeconomic and Natural Factors on Pulmonary Tuberculosis Incidence in China (2013-2019) using Explainable Machine Learning: A Nationwide Study

Pulmonary tuberculosis (PTB) stands as a significant and prevalent infectious disease in China. Integrating 13 natural and socioeconomic factors, we conduct nine machine learning (ML) models alongside the Tree-Structured Parzen Estimator to predict the monthly PTB incidence rate from 2013 to 2019 in mainland China. With explainable ML techniques, our research highlights that population size, per capita GDP, and PM10 concentration emerge as the primary determinants influencing the PTB incidence rate. We delineate both the independent and interactive impacts of these factors on the PTB incidence rate. Furthermore, crucial thresholds associated with factors influencing the PTB incidence rate are identified. Taking factors that have a positive effect on reducing the incidence rate of PTB as an example, the thresholds at which the effects of factors PM2.5, PM10, O3, and RH on the incidence rate change from increase to decrease are 105.5 μg/m3, 75.5 μg/m3, 90.8 μg/m3, and 72.3% respectively. Our work will contribute valuable insights for public health interventions.

Active Case Finding among Adults using an Individual's Vulnerability Score for Pulmonary Tuberculosis in a Rural Village of Goa: A Cross-sectional Study.

"Detect-Treat-Prevent-Build" to achieve tuberculosis (TB)-free India is envisaged in the National Tuberculosis Elimination Program (NTEP). To be able to achieve this, it is important to address the fact that the most vulnerable and hard-to-reach groups need to undertake screening. The present review aimed to examine the vulnerability in connection with TB disparities faced by distinct sub-populations generally viewed as vulnerable and follow these for testing. The community-based cross-sectional study was conducted in the field practice area of sub-center Carambolim in a rural area of Goa for 3 months. The households were visited, and data collected via personal interviews were recorded on the questionnaire study tool. Based on the data, the participants' vulnerability mapping was done per the parameters identified. Among 223 households, 528 persons were screened for vulnerability. The 47 highly vulnerable participants were advised sputum CBNAAT, of which 9 (19%) tested positive for pulmonary TB, while of the 86 moderately vulnerable participants, 4 (5%) tested positive for pulmonary TB. Among the 34 with symptoms suggestive of TB, 3 (9%) tested positive for pulmonary TB. The study detected 16 new TB patients from the population and found a higher incidence of pulmonary TB among the vulnerable group with no symptoms of Pulmonary TB. A further state-wide survey is recommended to diagnose such cases.

Mapping TB incidence across districts in Uganda to inform health program activities.

Identifying spatial variation in TB burden can help national TB programs effectively allocate resources to reach and treat all people with TB. However, data limitations pose challenges for subnational TB burden estimation. We developed a small-area modeling approach using geo-positioned prevalence survey data, case notifications, and geospatial covariates to simultaneously estimate spatial variation in TB incidence and case notification completeness across districts in Uganda from 2016-2019. TB incidence was estimated using 1) cluster-level data from the national 2014-2015 TB prevalence survey transformed to incidence, and 2) case notifications adjusted for geospatial covariates of health system access. The case notification completeness surface was fit jointly using observed case notifications and estimated incidence. Estimated pulmonary TB incidence among adults varied >10-fold across Ugandan districts in 2019. Case detection increased nationwide from 2016 to 2019, and the number of districts with case detection rates >70% quadrupled. District-level estimates of TB incidence were five times more precise than a model using TB prevalence survey data alone. A joint spatial modeling approach provides useful insights for TB program operation, outlining areas where TB incidence estimates are highest and health programs should concentrate their efforts. This approach can be applied in many countries with high TB burden.

Spatial Analysis of Pulmonary Tuberculosis Incidence in Kupang City in 2019-2021

Abstract Introduction: Pulmonary tuberculosis has a fairly high number of cases in several regions of Indonesia, including Kupang City. In 2019, tuberculosis cases in Kupang City amounted to 667 cases, in 2020 it increased to 693 cases and in 2021 it decreased to 419 cases. This study aims to analyze the factors that influence the incidence of pulmonary tuberculosis which are studied in a spatial analysis model.Methods : This research is a quantitative research with an analytical observational design using an approach to Geographic Information Systems (GIS). This study aims to see the autocorrelation of population density, poor families, and healthy homes with the incidence of pulmonary tuberculosis and to see the pattern of relationships that are formed.The data used in this research is secondary data taken from related agencies. The samples in this study were 11 community health centers in Kupang City, namely Naioni Health Center, Alak Health Center, Manutapen Health Center, Sikumana Health Center, Penfui Health Center, Bakunase Health Center, Oebobo Health Center, Oepoi Health Center, Pasir Panjang Health Center, Kupang City Health Center, and Oesapa Community Health Center. Spatial analysis uses computer programs, namely the QGIS and GeoDa applications. QGIS was used to produce a map of the distribution of pulmonary tuberculosis cases in 11 health centers in Kupang City in 2019-2021 and the GeoDa application was used to see the pattern of TB distribution in Kupang City in 2019-2021, in general or globally through the LISA (Local Indicators Spatial Autocorrelation) tests.Results: Based on the results of the LISA (Local Indicators Spatial Autocorrelation) bivariate test, it shows that population density, poor families, and healthy housing coverage have no relationship with the incidence of TB in Kupang City (p-value &gt; 0.05) and show a random pattern of case distribution (Morans Index ' I is smaller than E[I] = -0.1000). However, in 2019-2020, the Morans I Index value covering healthy homes was greater than E[I] = -0.1000, which shows a clustered pattern of case distribution.Conclusion: It was concluded that there was no positive spatial autocorrelation between population density, poor families, and healthy homes with the incidence of pulmonary tuberculosis in Kupang City in 2019-2021

Determinant of Pulmonary Tuberculosis in Outpatients at Daya Hospital, Makassar City

Indonesia ranks third with the highest number of TB patients in the world after India and China. Initial data collection conducted at Daya Kota Makassar Regional General Hospital revealed that Pulmonary Tuberculosis is among the top 10 diseases in both outpatient and inpatient cases. The incidence of Pulmonary TB in outpatient cases was 783 in 2019, 210 in 2020, and 238 in 2021. The objective of this research is to determine the determinants of pulmonary tuberculosis incidence in outpatient patients at Daya Kota Makassar Regional General Hospital. The research method employed is quantitative research with a cross-sectional design. The population for the study includes all outpatient patients in the Pulmonary Clinic of Daya Kota Makassar Regional General Hospital, totaling 142 individuals, with a subject of 49 subjekts selected using purposive sampling technique. Bivariate analysis uses Chi-square, and multivariate analysis employs logistic regression. The research results indicate a correlation between knowledge (p-value=0,004), smoking behavior (p-value=0,003), and nutritional status (p-value=0,019) with the incidence of Pulmonary Tuberculosis. However, there is no socio-economic relationship with Pulmonary Tuberculosis incidence (p-value=0,169) at Daya Kota Makassar Regional General Hospital. It is recommended that the community participate in the socialization activities for preventing the risk of Pulmonary Tuberculosis provided by health cadres to reduce the incidence of Pulmonary Tuberculosis.

THE RELATIONSHIP BETWEEN THE PHYSICAL CONDITION OF THE HOME ENVIRONMENT AND HISTORY OF DISEASE WITH THE INCIDENCE OF TUBERCULOSIS IN THE WORKING AREA OF THE RANGKASBITUNG HEALTH CENTER IN 2023

This study aims to determine the relationship between the physical condition of the home environment and history of disease with the incidence of tuberculosis or pulmonary tuberculosis in the work area of the Rangkasbitung Health Center in 2023. This study is a descriptive correlation study with cross sectional design, which is research that explores the relationship between the physical condition of the house and the behavior of residents towards the incidence of tuberculosis. The type of data used is primary data, from the results of questionnaires and secondary data obtained from recording and reporting TB patient visit data at the Rangkasbitung Health Center. Data analysis in the study, using univariate analysis with positive TB incidence results (69.2%); Bivariate analysis showed a relationship between home air circulation and the incidence of tuberculosis (P&lt;0.028), occupancy density (P&lt;0.011), lighting (P&lt;0.015), humidity (P&lt;0.020), education (P&lt;0.002), employment (P&lt;0.006), and smoking (P&lt;0.009); and humidity factor being the dominant factor with the largest OR (OR=28.579). The results of the cross-sectional test in the study, showed a significant relationship between the physical condition of the home environment and the history of disease with the incidence of tuberculosis in the work area of the Rangkasbitung Health Center. Suggestions in this study are the need for education related to environmental factors and behaviors that cause tuberculosis, such as counseling about healthy homes with qualified ventilation, good lighting, good humidity, occupancy in an adequate place, and reducing cigarette use habits. Other factors that need to be improved, in order to support the reduction in TB prevalence rates, namely education and employment factors. Patients with pulmonary tuberculosis must also be given understanding, related must always be tried to be in a place that has adequate air ventilation and good humidity, in order to reduce the risk of the severity of TB disease which can lead to death or the duration of the treatment process.

The Relationship between House Conditions and the Household Contacts with the Incidence of Children's Pulmonary Tuberculosis

Tuberculosis (TB) is a high risk in vulnerable groups with low immunity, such as children. Environmental factors and household contacts influence the high incidence of tuberculosis. This study aimed to analyze the relationship between housing conditions and the presence of household contacts with the incidence of pulmonary tuberculosis in children. This study used a case-control design. This study used a case-control design at the Puskesmas Kedaton Bandar Lampung from December 2023 to January 2024. The total sample was 58 children (29 cases and 29 controls), selected using Simple Random Sampling. The variables of this study were residential density, humidity, lighting, floor type, ventilation area, and the presence of household contacts. This study used univariate analysis, bivariate analysis with chi-square, and multivariate with multiple logistic regression. This study shows that there is a relationship between lighting (p=0,008), ventilation area (p=0,032), and the presence of household contacts (p&lt;0,001) with the incidence of pulmonary TB in children. The factor most associated with the incidence of pulmonary TB in children was lighting (OR=6.061; 95% CI=1.768-20.777), which means children with home lighting that doesn't meet the requirements have a 6.061 times higher risk of experiencing childhood pulmonary TB than those who meet the lighting requirements.