Incidence Of Infection In Newborns Research Articles

Multifactorial Colonization of the Pregnant Woman's Reproductive Tract: Implications for Early Postnatal Adaptation in Full-Term Newborns.

This retrospective study aimed to investigate the impact of microorganisms identified in the reproductive tract on disorders during the early adaptation period in newborns. A cohort of 823 patients and cervical canal cultures were analyzed to identify the presence of microorganisms. Newborns included in the study were divided into two groups due to the number of pathogens identified in the swab from the cervical canal of the mother. The first group consisted of newborns whose mothers had one pathogen identified (N = 637), while the second group consisted of newborns whose mothers had two or more pathogens identified (N = 186). The analysis of disorders of the early adaptation period included the incidence of respiratory distress syndrome, the number of procedures performed with the use of CPAP, oxygen therapy, antibiotic therapy and parenteral nutrition. Respiratory distress syndrome was more common in group II than in group I (85 vs. 31, p = 0.001). In group II, CPAP (63 vs. 21, p = 0.001), oxygen therapy (15 vs. 8, p = 0.02) and antibiotics were used more frequently (13 vs. 8, p = 0.01). The findings of this study revealed that the number of pathogens colonizing the reproductive tract had a significant influence on the early adaptation period in newborns. Multifactorial colonization of the reproductive tract was associated with an increased incidence of infections in newborns and a higher prevalence of acid-base balance disorders. This study highlights the importance of monitoring and addressing the microbial composition of the reproductive tract during pregnancy.

Analysis of pregnant women coagulopathy biomarker factors on covid-19 infection in the fetal

Background: Of the 62 babies born, 20 (32 percent) were infected with covid-19, the average age of premature birth.Purpose: To analyze the relationship between coagulopathy biomarker factors in pregnant women infected with covid-19 and the incidence of covid-19 infection in newborns.Method: Cross-sectional with the retrospective method. The inclusion criteria were babies born from mothers infected with covid-19, and newborns aged 0-28 days. The number of samples is 145. The sampling technique is purposive sampling. The data collection instrument is an observation sheet. Data were collected for 12 weeks from hospital medical records. Analysis of chi-square test data and independent t-test.Results: Participants were young adults as much as 86 (61.4 percent). Gestational age-based delivery was premature as much as 55 (37.9 percent). The gestational age range at delivery is 28 weeks to 41 weeks, gestational age when infected with covid-19 trimester III a gestational age range is from 29 weeks to 41 weeks. Coagulopathy biomarker values experienced There were 140 abnormal D-dimers with a range of >500 (96.6 percent). All babies are born of mothers infected with covid-19, less than 0 days after birth, 39 were infected (27.1 percent) were infected with covid-19 at <0 days. D-dimer coagulopathy biomarkers exist a significant relationship (p-value < 0.05) against infection of newborns from the inside Womb.Conclusion: Coagulopathy biomarker factors in pregnant women are related to the occurrence of babies infected with covid-19. Where the incidence of infection in newborns has occurred since zero days born.

Teknik Perawatan Tali Pusat terhadap Pelepasan Tali Pusat

The incidence of infection in newborns (BBL) in Indonesia is 24%-34%. Infection in BBL is the number 2 cause of neonatal death by 49%-60%. Neonatal mortality in developing countries is 50% due to umbilical cord infection, sepsis and neonatal tetanus. The purpose of this study was to analyze the effectiveness of umbilical cord care in newborns using dry open technique and sterile gauze against umbilical cord rupture. The type of research was pre-experimental post-test only design and the sample of this study was 30 newborns at the Puskesmas with purposive sampling technique. The study was conducted for 3 months. The results showed that the umbilical cord care technique with the dry open method made the umbilical cord detach faster than the sterile gauze method. The time for releasing the umbilical cord with the dry open method took 123.8 hours and the time for releasing the umbilical cord with sterile gauze took 170.8 hours. The results of the analysis showed the significance value of 0.004 and the Levin test result of 138%. Conclusion there is no more effective between sterile gauze and dry open umbilical cord treatment against umbilical cord detachment. Suggestions for midwives and health workers can socialize postpartum mothers in umbilical cord care for newborns using open techniques and sterile gauze.

GAMBARAN KETUBAN PECAH DINI, WARNA KETUBAN JELEK DAN INFEKSI IBU DENGAN KEJADIAN INFEKSI PADA BAYI BARU LAHIR DI RSUD ABDUL WAHAB SJAHRANIE SAMARINDA

The early 28 days of life called the neonatal period is the most vulnerable period for infants. The infants face the highest risk of death in the first month after birth. The most common cause of infant death is asphyxia, prematurity, and infection. Infection in newborns is defined as a condition where the newborns have a disease caused by microorganisms. One of the risk factors causing infection in newborns includes factors from the mother, such as premature rupture of membranes, green or meconium and smelly amniotic fluid, maternal infection, and others. The main objective of this research was to describe the risk factors of incidence of infection in newborns at RSUD Abdul Wahab Sjahranie Samarinda. This research uses a retrospective descriptive method with the cross-sectional approach. Sampling was done by taking data on medical records of patients at the RSUD Abdul Wahab Sjahranie Medical Record Installation using total sampling technique. The results obtained were 99 samples that met the inclusion and exclusion criteria with details of patients who experienced premature rupture of membranes by 18 people (18,2%), poor amniotic color by 62 people (62,6%), mothers who had leukocytosis by 15 people (15,2%), and the incidence of infection in newborns by 2 people (2%). the collected data were tabulated bu frequency and percentage and displayed in tables

Co-occurrence of human papillomavirus (HPV) in newborns and their parents

BackgroundThe potential HPV transmission route includes horizontal transmission “in utero” and vertical transmission from parents. Less is known about the role of child’s father as a potential source of HPV infection and involved in the pathogen’s epidemic chain. A possible consequence of perinatal infection includes HPV-related childhood diseases and carrying the risk of cervical cancer development in female offspring. In view of the evidence, studies of HPV co-occurrence in one or both parents and their offspring seem vital for the implementation of respective preventive measures. Consequently, the aim of this study was to determine the incidence of common HPV 16/18 infections in newborns and their parents, and to assess its role of the periconceptional transmission.MethodsTo determine the incidence of common HPV infections in newborns from single pregnancies and their parents. The study included 146 pregnant women, as well as their partners, and newborns. They were tested for the presence of HPV 16/18 DNA using the PCR method. HPV types 16 and/or 18 were identified using type-specific PCR primers. The quality of the extracted DNA was evaluated by PCR using PC03/PC04 β-globin-specific primers. The relationship between the presence of neonatal and parental HPV infection was analyzed using a multivariable regression model. Calculations were carried out with the Statistica 10.ResultsThe presence of HPV DNA was detected in 19 (13,01%) newborns, 28 (19,18%) mothers, and 20 (13,7%) fathers. The viral DNA was detected in 14 newborns delivered by HPV-positive mothers (OR = 26,08; CI: 8,07-84,31, p < 0.001), 12 descendants of HPV-positive fathers (OR = 22,13; CI: 6,97-70,27, p < 0.001), and 10 children originating from two infected parents (OR = 24,20; CI: 6,84–85,57 p < 0.001). Those findings points to a increase risk of an acquired infection in newborns with HPV-positive parents.ConclusionOur findings suggest the possible role of the periconceptional transmission in the mode of acquired HPV 16/18 infections.

HUBUNGAN PERAWATAN TALI PUSAT DENGAN KEJADIAN INFEKSI PADA BAYI BARU LAHIR DI RSUD Dr. PIRNGADI MEDAN 2019

Umbilical cord care is one treatment procedure that aims to treat the umbilical cord in newborns to keep it dry and prevent infection. Improper treatment of the umbilical cord in an infant will experience an infectious disease. This study uses a correlation design with a cross sectional approach is something that connects / analyzes the variables that aim to determine the relationship of umbilical cord care with the incidence of infection in newborns (BBL) in RSUD Dr. Pirngadi Hospital Medan 2018, with a sample of 35 respondents. The instruments included demographic data, 20 umbilical cord care questionnaires and observation sheets for infection. Based on the results of this study, the majority of people doing good umbilical cord care (score 14-20) as many as 30 (85.7%) while the minority of respondents doing umbilical cord care enough (score 7-13) as many as 5 people (14.2%). the majority did not experience an infection score of 0 (zero) as many as 33 people (94.3%) and the minority experienced infection score 1-5 as many as 2 people (5.7%). Based on Chi Square test, p = 0.017 &lt;0.05 means that Ho is rejected and Ha is accepted. This shows a relationship between cord care and the incidence of infection in newborns (BBL). It is expected that nurses to carry out umbilical cord care measures more effectively in accordance with the SOP so as to avoid the number of infections in newborns and the next researcher makes an observation sheet in measuring cord care performed by nurses.

Analysis of Long-Term Dynamics of Incidence of Healthcare-Associated Infections in the Irkutsk Region

Introduction.Healthcare-associated infections incidence is one of the most pressing issues in modern healthcare due to their high abundance as well as economic loss they cause.The aimis to study regional features of the incidence of healthcare-associated infections.Methods.We conducted a retrospective epidemiological analysis of nosocomial morbidity in hospitals of the Irkutsk region within 2006-2017 years. We used data, presented in the following state reports: “On the state of sanitary and epidemiological welfare of the population in the Russian Federation”, “On the state of sanitary and epidemiological welfare of the population in the Irkutsk region”.Results and discussion.According to the results of the conducted analysis, it was shown that the average long-term prevalence of healthcare-associated infections in the Irkutsk region was 41.94 ± 2.040/00000 (Russian Federation – 17.49) with a tendency to stabilization in recent years. The therapeutic and prophylactic organizations of the surgical profile have the highest epidemiological significance (over 51 %). At the same time, the share of postoperative complications during the study period decreased by 1.5 times. We have noted a rising trend line with a positive rate of increase in the incidence of nosocomial pneumonia, which in the last two years has taken a leading position in the structure of healthcare-associated infections. The incidence of infections in newborns in the Irkutsk region ranks the third, with a specific weight of 11.54 %. Moreover, if before 2013 purulent-septic diseases of the newborns were the predominant nosological form, in recent years pneumonia has firmly taken over the leadership. During the study period we revealed an increase in the incidence of postpartum endometritis in puerperas. It has been shown that the registration of sepsis, urinary tract infections in the region is low.

Effectiveness of a prematurity-based protocol for management of infants born to mothers with Group B Streptococcus colonisation

The aim of this study was to validate the efficacy of a protocol for the management of infants born to colonised mothers with Group B Streptococcus (GBS). We studied a cohort of newborns admitted at the A. Gemelli University Hospital between May 2006 and December 2009. A total of 1,108 were newborns of mothers with GBS; 178 were children of mothers with unknown GBS status. Newborns were managed according to the care protocol in use at our division. Infected infants were born to mothers who underwent inadequate intrapartum antibiotic prophylaxis (IAP). No mother with complete IAP had an infected newborn. The incidence of invasive GBS infection in newborns of mothers with GBS was 0.4% and in newborns of mothers with unknown GBS status was 2.2%. Only 17.4% of newborns of mothers with GBS had risk factors. The complete IAP should always be performed regardless of the presence or the absence of risk factors. The care protocol applied offers successful management of the newborns of mothers with GBS, based on the correct execution of IAP, considering as a primary risk factor, the gestational age of < 35 weeks.