The effect of timing of preemergence application ofN,N-dimethyl-2,2-diphenylacetamide (diphenamid) on phytotoxicity to pepper(Capsicum annuumL.), efficacy of weed control, and damping-off incidence was studied in greenhouse and field experiments. Delay of application from day of sowing to close to emergence reduced phytotoxicity to pepper while only partially reducing herbicidal action. Addition of a mixture of the contact nonresidual herbicides 6,7-dihydrodipyrido[1,2-a:2′,1′-c]pyrazinediium ion (diquat) and 1,1′-dimethyl-4-4′-bipyridinium ion (paraquat) to a late preemergence application of diphenamid resulted in control of weed seedlings which emerged after sowing of pepper and significantly increased the yield. The increase ofRhizoctoniadamping-off incidence due to diphenamid was also reduced by delayed application.