Objective To investigate the present situation of nurse's metabolic syndrome, and explore the correlation between diet, behavior and occupational stress and nurse's metabolic syndrome. Methods In April to May 2015, using stratified cluster random sampling method, a total of 393 nurses in Fuzhou were investigated by physical examination, blood tests, Nurse Stressor Scale (NSS) and a general information questionnaire for metabolic syndrome and its influencing factors. Totally 393 questionnaires were distributed and 380 valid questionnaires were collected. Results There were 54 cases of metabolic syndrome among 380 nurses, accounting for 14.21%. Logistic regression analysis showed that age, working age, occupational stress, sleep time, the amount of meat in diet, cooking oil were the risk factors of metabolic syndrome (P<0.05) . The physical exercise and the quantity of vegetables in diet were the protective factors of metabolic syndrome (P<0.05) . Conclusions Unreasonable diet, inadequate exercise and occupational stress are the factors that affect the metabolic syndrome in nurses, which are related to their professional characteristics. Key words: Nurses; Metabolic syndrome; Diet; Behavior; Occupational stress; Influencing factors