Among adolescents, it is estimated that for every suicide, there are 100–200 suicide attempts, with rates varying by country due to local or individual factors. This study aimed to estimate the prevalence and correlates of suicide attempts among in-school adolescents in Saint Lucia using data from the 2018 Global School-based Health Survey. The study included 1,970 in-school teenagers aged 13-18 years. Multi-binomial logistic regression was used to determine predictors of suicide attempts with adjusted odds ratios (AOR) and 95% confidence intervals (CI). The prevalence of suicide attempts among inschool teenagers in Saint Lucia was 16.2%. Factors associated with suicide attempts included being female (AOR 3.001, 95% CI 2.026-4.445), being physically attacked (AOR 0.573, 95% CI 0.388- 0.846), feeling lonely (AOR 0.447, 95% CI 0.294-0.678), worrying and sleeplessness (AOR 0.542, 95% CI 0.336-0.875), and having made suicide plans (AOR 0.051, 95% CI 0.035-0.073).