Improve Body Composition Research Articles

Effects of MyBFF@school, a multifaceted obesity intervention program, on anthropometry and body composition of overweight and obese primary schoolchildren

BackgroundRecently, there has been an increase in the prevalence of childhood obesity in Malaysia, raising concerns about increased cardiometabolic morbidity. MyBFF@school is a multifaceted program comprising physical activity, nutritional education, and psychological empowerment introduced to combat childhood obesity in Malaysia. The efficacy of a six-month intervention on the body composition of overweight and obese primary schoolchildren was evaluated.MethodsThis is a school-based, cluster randomized controlled trial involving selected primary schools in Kuala Lumpur, Selangor, and Negeri Sembilan. A total of 1,397 primary-school students aged 9–11 with a body mass index (BMI)z-score (corrected for age) greater than + 1 standard deviation based on the World Health Organization 2007 Growth Reference were assigned to intervention (n=647) and control (n=750) groups. BMI z-score, waist circumference (WC), percentage body fat (PBF), and skeletal muscle mass (SMM) were assessed at baseline and after three and six months of the study. Analyses of all outcomes except for the baseline characteristics were conducted according to the intention-to-treat principle.ResultsAfter three months, there was no significant difference in the BMI z-score or PBF between the control and intervention groups, but SMM and WC were significantly higher in the intervention group versus the control group with mean difference of 0.15 kg; 95% confidence interval [CI]: 0.07–0.22, p < 0.001 and mean difference of 1.53 cm; 95% confidence interval [CI]: 1.21- 1.85, p < 0.001 for SMM and WC respectively. After six months, the intervention group demonstrated a significantly greater reduction in PBF compared to the controls (% mean difference: 0.43%, 95% CI: − 0.73 to − 0.12, p < 0.001) as well as a greater increase in SMM (mean difference: 0.28 kg, 95% CI: 0.18–0.37, p < 0.001). There was no difference in the BMI z-score or WC between the intervention and control groups at six months.ConclusionsThe multicomponent MyBFF@school intervention significantly improved body composition among obese primary schoolchildren in terms of percentage body fat and skeletal muscle mass compared to the control after six months. However, BMI z-score and waist circumference measures did not reflect the benefits of this program.Trial registrationClinical trial number: NCT04155255, November 7, 2019 (Retrospective registered). National Medical Research Register: NMRR-13–439-16,563. Registered July 23, 2013. The intervention program was approved by the Medical Research and Ethics Committee (MREC), Ministry of Health Malaysia and the Educational Planning and Research Division (EPRD), Ministry of Education Malaysia. It was funded by the Ministry of Health Malaysia.

Longitudinal changes in the 6-minute walk test and the Glittre-activities of daily living test in adults with cystic fibrosis.

With the increasing use of highly effective modulator therapy (HEMT) in adults with cystic fibrosis (awCF), it is necessary to determine the evolution of the most dynamic physiological markers of this disease, such as the 6-minute walk test (6MWT) and the Glittre-activities of daily living test (TGlittre). The present study aimed to evaluate the 1-year changes in the 6- minute walking distance (6MWD), TGlittre time, and quality of life (QoL) in awCF before the initiation of HEMT and to determine the impact of habitual physical activity (HPA) and chest physiotherapy (CP). This longitudinal study enrolled 24 awCF who completed the 6MWT and TGlittre. Pulmonary function tests, handgrip strength (HGS), and the Cystic Fibrosis Questionnaire-Revised (CFQ-R) were conducted. Measurements were collected at baseline (T1) and 1 year later (T2). The median body mass index increased between T1 and T2 [19.8 (18-24) vs. 21.4 (19-24) kg/m2, p=0.038]. TGlittre time decreased both in relation to the absolute values [3.10 (2.52-3.39) vs. 2.40 (2.00-3.00) minutes, p=0.001] and in relation to the predicted values [127 (116-150) vs. 108 (102-140) % predicted, p=0.001]. Although there was no increase in 6MWD relative to the predicted values, it increased relative to the absolute values [545 (463-654) vs. 617 (540-658) meters, p=0.041]. In relation to the group that did not engage in HPA, individuals who had HPA showed an increase in HGS between T1 and T2 [7.1 (0-20) vs. 0 (-12-3) kgf, p=0.031]. In relation to the group that did not undergo CP, individuals undergoing CP showed an increase in the 'treatment burden'-CFQ-R between T1 and T2 [16.1 (-3-18) vs. -11.2 (-28-1) points, p=0.049]. In conclusion, awCF performed better on TGlittre than on 6MWT. They experienced an improvement in body composition. HPA was correlated with peripheral muscle strength, as were CP and QoL.

Effectiveness of Early Versus Late Time-Restricted Eating Combined with Physical Activity in Overweight or Obese Women.

To evaluate the effectiveness of a dual approach involving time-restricted eating (TRE) at different times of the day combined with physical activity (PA) on functional capacity and metabolic health in overweight or obese women. Random allocation of sixty-one participants into four groups: early time-restricted eating plus physical activity (ETRE-PA, n = 15, 31.8 ± 10.76 years, 89.68 ± 13.40 kg, 33.5 ± 5.53 kg/m2), late time-restricted eating with physical activity (LTRE-PA, n = 15, 30.60 ± 7.94 years, 94.45 ± 15.36 kg, 34.37 ± 7.09 kg/m2), late time-restricted eating only (LTRE, n = 15, 27.93 ± 9.79 years, 88.32 ± 10.36 kg, 32.71 ± 5.15 kg/m2) and a control group (CG, n = 15, 36.25 ± 11.52 years, 89.01 ± 11.68 kg, 33.66 ± 6.18 kg/m2). The intervention lasted for 12 weeks in all groups. Both the ETRE-PA and LTRE-PA groups engaged in a rigorous combined aerobic and resistance-training program. Significant reductions in body weight and body mass index were observed in the ETRE-PA and LTRE-PA groups compared to the CG and LTRE groups post-intervention (p < 0.0005). Only the ETRE-PA group exhibited a significant decrease in fat mass (p = 0.02), low-density lipoprotein cholesterol (p = 0.01), and aspartate aminotransferase (p = 0.002). Significant reductions in alanine aminotransferase levels were observed in the ETRE-PA (p = 0.004) and LTRE-PA (p = 0.02) groups. These two latter groups achieved higher performances in the 6-min walking test, bench press, 30-s squat, crunch test, vertical jump (p < 0.0005 for both), and leg extension (p < 0.02 for both) when compared to the LTRE and CG groups. The integration of TRE with PA leads to greater improvements in body composition, lipid profile, and physical performance, with no significant differences between the ETRE-PA and LTRE-PA approaches. This combined strategy offers a promising solution for overweight and obese women.

Eight Weeks of Resistance Training Is Not a Sufficient Stimulus to Improve Body Composition in Post-COVID-19 Elderly Adults

Background: This study sought to assess how body mass (BM) and body composition in post-COVID-19 elderly adults were affected by 8 weeks of resistance training. An additional goal was to determine the agreement between Bioelectrical Impedance Analysis (BIA) and Dual Energy X-Ray Absorptiometry (DXA) in elderly people. Methods: Participants were randomly assigned to an intervention Group, which engaged in 8 weeks of resistance training, and a Control Group, which was advised to maintain their usual activity levels. Before and after the intervention, the body composition was analyzed via the BIA and DXA methods. Results: We found no statistically significant changes in BM or body composition following resistance training. BIA was found to overestimate the participants’ baseline BM and fat-free mass (FFM) and to underestimate the fat mass (FM), compared to the DXA method. There were no significant differences in intervention-induced changes in FM and FFM measured by BIA and DXA. Conclusions: Moderate intensity resistance training lasting 8 weeks was not found to be a sufficient stimulus to improve BM and body composition in post-COVID-19 elderly adults. We also conclude that BIA may serve as a viable alternative to DXA for measuring longitudinal changes in body composition in elderly people.

Time restricted eating: A revolutionary approach to combat obesity and enhance metabolic health

Overweight and obese people are growing in numbers due to the adoption of unhealthy lifestyle. Overweight and obesity leads to morbidity and mortality affecting every organ system within the body. Therefore, overweight and obese individuals modify the lifestyle through dietary changes. One dietary method which gets more recognition is Time Restricted Eating as one of Intermittent Fasting regimens. This past decade, many studies have found its beneficial impact on overweight and obese individuals. This review aims to summarize the effect of TRE on weight loss, body composition, and metabolic health. This review gives a comprehensive understanding on concept of TRE and how could TRE be beneficial. This review also compares TRE to other IF regimens to find the most appropriate IF regimens. Articles from Google Scholar were obtained. A total of 90 articles were then included in this literature review. This review reveals that TRE is a promising dietary method on weight loss and improvement of body composition. On metabolic health, some studies reported changes while others reported otherwise. When compared to other IF regimens, TRE results in no greater impact leading to a similar result of every IF regimen. TRE switches metabolism and improves circadian rhythm and oxidative stress. These findings imply the beneficial impact of TRE on overweight and obese people.

Increased copeptin may reflect vasopressin-related metabolic changes after bariatric surgery.

Mechanisms underlying metabolic improvement following metabolic and bariatric surgery (MBS) may provide insight into novel therapies. Vasopressin improves body composition and protects against hypoglycemia. Associations of copeptin, a stable cleavage product of vasopressin, with BMI and insulin resistance suggest an adaptive increase in vasopressin to counteract metabolic disruption. To our knowledge, no study has investigated copeptin before and after MBS in humans. This study's aim was to investigate copeptin changes following MBS and associations with metabolic parameters. This was a 12-month longitudinal study of 64 youth (78% female; mean age 18.7 [SD 2.8] y) with obesity (mean BMI 45.6 [SD 6.8] kg/m2) undergoing MBS (n = 34) or nonsurgical (NS) lifestyle management (n = 30). Fasting copeptin, hemoglobin A1c (HbA1c), homeostatic model assessment for insulin resistance (HOMA-IR), body composition, and resting energy expenditure (REE) were assessed. Over 12 months, copeptin increased more (time-by-treatment p = 0.017) whereas HbA1c and adiposity decreased more after MBS than NS (ps ≤ 0.036). Copeptin changes correlated negatively with percentage fat mass and REE changes (rho ≤ -0.29; ps ≤ 0.025) in the whole group, and they correlated positively with HbA1c and HOMA-IR (rho ≥ 0.41; false discovery rate-adjusted p = 0.05) and negatively with REE changes (rho = -0.55; false discovery rate-adjusted p = 0.036) in the MBS group. Increases in copeptin after weight loss in MBS compared with NS were associated with lower REE and higher HbA1c/HOMA-IR values. Vasopressin may contribute to MBS-related metabolic modifications.

Assessment of Body Composition, Bone Density, and Biochemical Markers of a Natural Bodybuilder During Contest Preparation

This case study aimed to evaluate the body composition and several biochemical markers during a 7-month pre-competition training period of a natural male bodybuilder. The athlete monitored his nutrition, training variables, and daily physical activity during the preparation phase. At the beginning (W31), in the middle (W18), and one week before the contest (W1), measurements included body composition via DEXA, testosterone and cortisol hormonal concentrations, and lipid, blood, and liver biochemical markers via an automated hematology analyzer. A gradual decrease in energy intake (−27.6%) and increased daily activity (169.0%) was found. Fat mass decreased from 17.9 kg (W31) to 13.1 kg (W18) and 4.2 kg (W1), while lean body mass decreased from 69.9 kg (W31) to 68.2 kg (W18) and 66.7 kg (W1). Bone density decreased linearly, and bone mass decreased from W31 to W1 by 1.7%. Testosterone decreased from 5.4 ng·mL−1 (W31) to 5.3 ng·mL−1 (W18) and 4.4 ng·mL−1 (W1), while cortisol increased from 21.3 μg·dL−1 (W31) to 20.3 μg·dL−1 (W18) and 24.4 μg·dL−1 (W1). In conclusion, a slow rate of weight loss and training with repetitions nearly to failure, combined with weekly monitoring of training and nutrition, may significantly improve body composition. However, hormone concentration and bone mass will experience mild negative effects.

The Effect of Resistance and/or Aerobic Training on Quality of Life, Fitness, and Body Composition in Prostate Cancer Patients-A Systematic Review and Meta-Analysis.

Background: Prostate cancer (PC) and its treatment are often associated with side effects such as fatigue, muscle loss, and diminished quality of life (QoL). Physical exercise, particularly resistance training (RT) and aerobic training (AT), has been suggested as a strategy to mitigate these effects. However, the comparative efficacy of RT, AT, and combined RT/AT on QoL, body composition, physical fitness, and laboratory markers in PC patients is still insufficiently understood. Methods: Randomized controlled trials (RCTs) investigating structured RT, AT, or combined RT/AT programs in PC patients undergoing various treatments were included. The primary outcome was QoL, assessed using EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires. Secondary outcomes included body composition, fitness, and laboratory parameters. The studies were sourced from PubMed, Embase, and CENTRAL through May 2024. The effect sizes were pooled using random-effects models, and the risk of bias was systematically assessed following the GRADE approach. Results: A total of 30 RCTs, encompassing 2216 PC patients, were analyzed. Combined RT/AT significantly improved QoL subdomains, including global health, and cognitive and sexual function, while reducing fatigue and urinary symptoms. RT alone improved body composition by increasing lean body mass and reducing body fat percentage. Both RT and combined RT/AT enhanced strength (chest and leg press) and VO2peak. No significant changes were observed in laboratory markers, such as PSA or lipid levels. The effects of isolated AT remain unclear due to limited data. Conclusions: RT and combined RT/AT significantly improve QoL, fitness, and body composition in PC patients, with no detectable effect on PSA or lipid levels. Further research is needed to elucidate the specific effects of AT and to investigate long-term outcomes.

Effects of a goal attainment theory-based intervention on physical activity, body composition, and motivation in emerging adults with physical inactivity: A randomized controlled trial.

This study aims to assess the effectiveness of an intervention based on the goal attainment theory to levels of physical activity, body composition, and motivational variables of emerging adults with physical inactivity. A randomized, controlled trial. A total of 157 emerging adults with physical inactivity were randomized into the control group (n=77) or the intervention group (n=80). The control group received routine health education for a period of 3 months, and the intervention group used a physical activity promotion intervention model based on King's attainment theory on the basis of the control group. The primary outcome was the body composition. Secondary outcomes were examined included levels of physical activity, motivation, and self-efficacy. The results indicate that the visceral fat area was significantly lower in the intervention group (Z = -6.79, P < 0.001), along with reductions in body fat mass (Z = -2.85, P < 0.05) and body fat percentage (F = -2.78, P < 0.05). The intervention group also demonstrated higher introjected motivation (Z = 2.70, P < 0.05) and self-efficacy (Z = 4.06, P < 0.001) than the control group. Physical activity levels were significantly higher in the intervention group, with increases observed in vigorous activity (Z = 60.51, P < 0.001), moderate activity (Z = 104.90, P < 0.001), walking activity (Z = 7.37, P < 0.001), and total physical activity (Z = 91.40, P < 0.001) compared to the control group. Physical activity interventions based on King's Attainment Theory can improve body composition, increase physical activity levels, improve exercise self-efficacy, and promote maintenance of healthy behaviours in emerging adults. This study was registered on ClinicalTrials (NCT05697679).

Efficacy of a Dietary Supplement Extracted from Persimmon (Diospyros kaki L.f.) in Overweight Healthy Adults: A Randomized, Double-Blind, Controlled Clinical Trial.

A single-center, randomized, double-blind, and placebo-controlled clinical trial assessed the efficacy in improving body composition and in weight management of a dietary supplement consisting of 400 mg of a standardized extract of the persimmon fruit (Diospyros kaki L.f.) in adult subjects with a BMI between 25 and 34.99 kg/m2 administered for 120 consecutive days. In total, 36 participants were assigned to the placebo group and 35 to the experimental group (registered at ClinicalTrials.gov (NCT05750342)). Primary analysis focused on overweight subjects (placebo, n = 26; experimental, n = 23). In this group, fat mass expressed in kg and percentage evaluated by both dual-energy X-ray absorptiometry (DEXA) and bioelectrical impedance analysis (BIA) decreased significantly (between-group differences p < 0.001) in those receiving the persimmon extract as compared with the placebo. No significant reduction in lean mass was observed, suggesting that the muscle mass was maintained during fat loss. The use of the investigational product improved classic anthropometric parameters to a statistically significantly greater extent than the placebo, including body weight, BMI, and waist and abdominal circumference (p < 0.001), in the overweight group. In the overall population, similar improvements were observed, with significant between-group differences (p < 0.001) in fat mass reduction and improvements in body composition. Changes in the biochemical lipidic, glycemic, and anti-inflammatory profile were not found, except for between-group significant differences (p < 0.001) in decreases in tumor necrosis factor-alpha (TNFα) and increases in total antioxidant capacity (TAC) in favor of the experimental condition. There was a significant increase in fecal fat excretion in the experimental group at the end of the study in subjects with low fecal fat (9%) at baseline. Consumption of the investigational product vs. placebo improved the quality of life, with significantly greater scores in the total score and the mental health component of the SF-12 questionnaire. The persimmon extract was safe and well tolerated.

Effects of Different Blood Flow Restriction Training Modes on Body Composition and Maximal Strength of Untrained Individuals.

The objective of this study was to examine the impacts of absolute cuff pressure blood flow restriction (A-BFR) training and incremental cuff pressure blood flow restriction (I-BFR) training, under equal cuff pressures, on body composition and maximal strength among untrained adults. Additionally, we aimed to compare these effects with those observed in high-load resistance training (HL-RT). Thirty-three adults without prior professional sports or resistance training experience were recruited and randomly assigned to three groups (n = 11 per group) for an 8-week training program, held three times weekly. The A-BFR group trained with a 20% 1RM load and a cuff occlusion pressure set at 190 mmHg. The I-BFR group initiated training with an occlusion pressure of 160 mmHg, which incrementally increased by 20 mmHg every two weeks, with other conditions mirroring those of the A-BFR group. The HL-RT group trained with a 70% 1RM load. All three groups demonstrated a statistically significant improvement in lower-body maximal strength (p < 0.01), with no significant differences observed among the groups (p > 0.05). A notable increase in left-leg muscle mass was seen across all groups (p < 0.05). However, total muscle mass, right-leg muscle mass, fat-free mass, BMI, bone mineral density, and bone mineral content remained relatively unchanged (p > 0.05), with no significant differences among the groups (p > 0.05). Only the HL-RT group exhibited a significant increase in left-leg thigh circumference (p < 0.05), while right-leg thigh circumference remained stable (p > 0.05), with no significant intergroup differences (p > 0.05). While A-BFR and I-BFR did not yield statistically significant differences in overall training outcomes, A-BFR demonstrated a slightly stronger potential. A-BFR and I-BFR achieved comparable gains in muscle strength and improvements in body composition to those seen with HL-RT. However, HL-RT demonstrated more significant improvements in leg circumference.

Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury-a randomized, double-blind, and placebo-controlled pilot study.

High-dose testosterone replacement therapy (TRT), paired with finasteride (type II 5α-reductase inhibitor), improves body composition, muscle strength, and bone mineral density (BMD) in older men, without inducing prostate enlargement-a side effect associated with TRT. Men with spinal cord injury (SCI) exhibit neuromuscular impairment, muscle atrophy, bone loss, and increased central adiposity, along with low testosterone. However, sparse evidence supports TRT efficacy after SCI. This parallel-group, double-blind, placebo-controlled, and randomized clinical trial (RCT) is a pilot study that enrolled men (N = 12) with low to low-normal testosterone and gait impairments after chronic motor-incomplete SCI. Participants received high-dose intramuscular TRT (testosterone-enanthate, 125 mg/week) with finasteride (5 mg/day) vs. vehicle+placebo for 12 months. Change relative to baseline was determined for body composition, musculoskeletal outcomes, and prostate size, with effect sizes calculated between groups using Hedges' g. Adverse events and feasibility were assessed. TRT + finasteride consistently increased testosterone (g = 1.16-3.08) and estradiol (g = 0.43-3.48), while concomitantly reducing dihydrotestosterone (g = 0.31-2.27). Very large effect sizes at both 6 and 12 months suggest TRT + finasteride increased whole-body fat-free (lean) mass (+3-4% vs. baseline, g = 2.12-2.14) and knee extensor (KE) whole-muscle cross-sectional area (+8-11% vs. baseline, g = 2.06-2.53) more than vehicle+placebo. Moderate-to-large effect sizes suggest TRT + finasteride increased KE maximal voluntary isometric torque (+15-40% vs. baseline, g = 0.47-1.01) and femoral neck and distal femur BMD from 6 months onward (g = 0.51-1.13), compared with vehicle+placebo, and reduced fat mass 9-14% within the whole-body, trunk, and android (visceral) regions at 12 months (g = 0.77-1.27). TRT + finasteride also produced small effect sizes favoring lesser prostate growth than vehicle+placebo (g = 0.31-0.43). The participant retention, drug compliance, and incidence and severity of adverse events were similar among the groups. These data provide proof-of-concept and rationale for larger RCTs aimed at discerning the impact of TRT + finasteride on body composition, musculoskeletal health, and physical function in men with SCI, along with effect sizes and variance of responses to assist in planning subsequent trials. ClinicalTrials.gov, identifier NCT02248701.

Effects of 10 Weeks of Walking With Mobile Step-Tracking Apps on Body Composition, Fitness, and Psychological State in Adolescents Who Are Overweight and Obese: Randomized Controlled Trial.

In recent decades, physical activity intervention programs have been developed to reduce overweight and obesity in adolescents. However, this population is considered hard to reach in physical activity programs due to lack of adherence and poor results. Interventions with mobile phones in the adolescent population with normal weight have shown benefits, so this line of research may provide benefits in adolescents with overweight or obesity, although it has not yet been explored in the scientific literature. This study aims to determine the changes produced by a 10-week intervention promoted during school lessons on physical education using step tracker mobile apps in out-of-school hours on physical activity, adherence to the Mediterranean diet, body composition, and the physical condition of adolescents who are overweight and obese, and to analyze the changes achieved by the 10-week intervention on the psychological state of adolescents who are overweight and obese. The study was based on a randomized controlled trial with an initial sample of 50 adolescents aged between 12 and 16 years (from the first to the fourth years of compulsory secondary education), whose body composition, physical activity level, physical condition, and psychological state were measured. Participants were divided into an experimental group (EG) and a control group (CG), where the EG performed a series of walking steps with a mobile app in their free time outside physical education classes. Adolescents in the CG continued to perform their physical activities as normal but did not use any mobile apps. Inclusion in the EG and CG was randomized, and the researchers were blinded. An increase was found in the EG in corrected arm girth (mean difference -0.46; P=.05), curl-up repetitions (mean difference -6.35; P=.02) and push-up repetitions (mean difference -2.27; P=.04) after the intervention. In the CG, there was a significant increase in hip girth (mean difference -1.37; P=.05), corrected thigh girth (mean difference -1.28; P=.04), and muscle mass (mean difference -0.87; P=.04), as well as a significant decrease in competence (mean difference 3.08; P=.03). The covariates gender and age showed an effect on corrected arm girth (gender: P=.04), curl-up repetitions (gender: P=.04) and push-up repetitions (gender: P=.04) in the EG; while in the CG it affected corrected thigh girth (gender: P=.04), adherence to the Mediterranean diet (gender: P=.04 and age: P=.047) competence (gender: P=.04 and age: P=.04) and relatedness (gender: P=.05 and age: P=.04). No significant differences were found when comparing changes in the CG and EG. A 10-week program of mobile app use by adolescents who are overweight and obese for physical activity outside of school hours does not appear effective in producing improvements in body composition, physical fitness, or adequate psychological state as it does not appear to significantly increase physical activity. ClinicalTrials.gov NCT06089876; http://clinicaltrials.gov/ct2/show/NCT06089876.

Analyzing the Impact of an 8-Week Structured Physical Activity Program on Health-Related Fitness in Bhutanese Seventh-Grade Students

Objectives. This study aimed to evaluate the impact of an 8-week physical activity program (PAP) on health-related fitness (HRF) components of seventh graders in Bhutan. Its emphasis areas included assessing the program’s effects on cardiorespiratory endurance, muscular strength, muscular endurance, flexibility, and body composition. Materials and methods. Sixty-two students were allocated into two groups using simple random sampling: a control group (n = 31) following the standard physical education curriculum and an experimental group (n = 31) participating in the PAP utilizing the FITT (frequency, intensity, time, and type) principle. Fitness Gram assessments were used to measure HRF before implementing the intervention. Independent t-tests were used to compare results between groups, whereas paired t-tests were used to compare pre-test and post-test scores within groups. Results. All HRF components demonstrated notable improvements in the experimental group. Cardiorespiratory endurance increased from a mean of 23.23 to 30.57 (p &lt; 0 .05), muscular strength — from 7.47 to 12.37 (p &lt; 0.05), muscular endurance — from a mean of 10.10 to 16.40 (p &lt; 0.05), and flexibility — from 27.98 to 29.85 (p &lt; 0.05). It was additionally observed an improvement in body composition, with a notable decline in BMI. Conversely, the control group showed a less significant decrease in flexibility and BMI, while demonstrating marked enhancements in cardiorespiratory endurance, muscular strength, and muscular endurance. Conclusions. The study indicates that the organized PAP was more effective than the standard physical education curriculum in improving HRF components. These findings suggest that the implementation of structured PA programs using the FITT principles can lead to enhanced physical fitness and health-related outcomes among children and young people.

Physical activity and cardiometabolic risk factors in sprint and jump-trained masters athletes, young athletes and non-physically active men

Abstract Objectives Assessing physical activity and cardiometabolic risk in masters athletes as an example of very high physical activity at old age. Methods Forty-three men were studied in full factorial design, either as sprint or jump-trained masters athletes (MA, n=10, age 60–75 years), as young sprint or jump-trained athletes (YA, n=10, age 20–35 years), older control participants (OC, n=11, age 60–75 years) or as young control participants (AC, n=12, age 20–35 years). We performed bio-electrical impedance analysis and assessed serum markers of lipids and glucose metabolism and C-reactive protein, structured training hours, and habitual activity via mobile actimetry. Results Body fat was greater in OC than in MA (23.9 [SD 4.2] % vs. 14.0 [SD 5.7] %, p&lt;0.001), and also greater than in YA and YC (both p&lt;0.001). Weekly training hours were comparable between MA and YA (7.9 [SD3.3] hours vs. 11.1 [SD 4.8] hours, p=0.69). Habitual walking distance was greater in MA than in OC (7,387 [SD 4,923] m/day vs. 4,110 [SD 1,772] m/day, p=0.039), and so was habitual running distance (667 [SD690] m/day vs. 132 [427] m/day, p&lt;0.001). HOMA-index was greater in OC than in MA (2.07 [SD 1.39] vs. 0.80 [SD 0.41], p=0.0039), and so was C-reactive protein (1.35 [SD 1.74] mg/l vs. 0.58 [SD 0.27] mg/ml, p=0.018), whereas serum lipids showed only moderate or no effect (all p between 0.036 and 0.07). Conclusions Improved body composition and physical activity levels in MA are associated with lower cardiometabolic risk, which seems more pronounced for insulin sensitivity and inflammaging than for lipid metabolism.

Gut microbiota and metabolic responses to a 12-week caloric restriction combined with strength and HIIT training in patients with obesity: a randomized trial

BackgroundNowadays, obesity has become a major health issue. In addition to negatively affecting body composition and metabolic health, recent evidence shows unfavorable shifts in gut microbiota in individuals with obesity. However, the effects of weight loss on gut microbes and metabolites remain controversial. Therefore, the purpose of this study was to investigate the effects of a 12-week program on gut microbiota and metabolic health in patients with obesity.MethodsWe conducted a controlled trial in 23 male and female patients with obesity. Twelve participants completed a 12-week program of caloric restriction combined with strength and HIIT training (INT, pre-BMI 37.33 ± 6.57 kg/m2), and eleven participants were designated as non-intervention controls (pre-BMI 38.65 ± 8.07 kg/m2). Metagenomic sequencing of the V3-V4 region of the 16S rDNA gene from fecal samples allowed for gut microbiota classification. Nuclear magnetic resonance spectroscopy characterized selected serum and fecal metabolite concentrations.ResultsWithin INT, we observed a significant improvement in body composition; a significant decrease in liver enzymes (AST, ALT, and GMT); a significant increase in the relative abundance of the commensal bacteria (e.g., Akkermansia muciniphila, Parabacteroides merdae, and Phocaeicola vulgatus); and a significant decrease in the relative abundance of SCFA-producing bacteria (e.g., the genera Butyrivibrio, Coprococcus, and Blautia). In addition, significant correlations were found between gut microbes, body composition, metabolic health biomarkers, and SCFAs. Notably, the Random Forest Machine Learning analysis identified predictors (Butyrivibrio fibrisolvens, Blautia caecimuris, Coprococcus comes, and waist circumference) with a moderate ability to discriminate between INT subjects pre- and post-intervention.ConclusionsOur results indicate that a 12-week caloric restriction combined with strength and HIIT training positively influences body composition, metabolic health biomarkers, gut microbiota, and microbial metabolites, demonstrating significant correlations among these variables. We observed a significant increase in the relative abundance of bacteria linked to obesity, e.g., Akkermansia muciniphila. Additionally, our study contributes to the ongoing debate about the role of SCFAs in obesity, as we observed a significant decrease in SCFA producers after a 12-week program.Trial registrationThe trial was registered on [05/12/2014] with ClinicalTrials.gov (No: NCT02325804).

The Endocrine and Body Composition Responses to Accentuated Eccentric Loading Performed in Cluster Sets During a Strength–Endurance Training Block

This study investigated the endocrine responses to accentuated eccentric loading (AEL) paired with cluster sets (CSs) versus traditional training (TRAD). Seventeen recreationally active subjects (male = 11, females = 6, age = 23.18 ± 4.15 yrs, height = 1.72 ± 0.1 m, body mass = 81.29 ± 22.18 kg, back squat-to-body mass ratio = 1.55 ± 0.33, and bench press-to-body mass ratio = 1.06 ± 0.28) were randomly allocated into AEL and TRAD groups and trained for 4 weeks. The training was performed during a strength–endurance block with the target load consisting of three sets of 10 repetitions. The AEL group performed three sets of 10 for the squat and bench press using AEL every other repetition (5 AEL repetitions per set). In this protocol, CSs were also performed as one AEL repetition plus one traditional repetition followed by 15 s rest. Resistance training was performed three days a week, whilst sprint and agility training were performed two days a week. Testosterone (T), cortisol (C), creatinine (CREA), fat mass (FM), and fat-free mass (FFM) were assessed pre- and post-test. With a series of 2 × 2 repeated-measure ANOVA, the differences in the means between the two training methods and across time were compared. No statistically significant differences in resting blood variables or body composition were observed between the AEL and TRAD protocols after 4 weeks of training. Whilst the results marginally favored the use of AEL, these results did not support significant improvements in body composition or hormonal responses.

Effect of Physical Activity Interventions on Health Parameters in Children and Adolescents with Intellectual Disabilities: A Systematic Review.

Intellectual disability (ID) encompasses diverse challenges that affect daily life and health. Sedentary behaviors, prevalent in this population, contribute to alarming health concerns, notably obesity and musculoskeletal issues. This review examines the role of physical activity (PA) interventions in addressing these health challenges among children and adolescents with ID. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The search was conducted in the Cochrane Library, PubMed, Scopus, and SPORTDiscus databases, using specific keywords aligned with the PICO framework (population, intervention, comparison, and outcome). From January 2013 to October 2024, a total of 5236 studies were identified, of which 17 met the inclusion criteria for this review according to PRISMA procedures. Randomized controlled trials (RCTs) focusing on the impact of PA on body composition, physical fitness, bone health, metabolic indicators, and overall quality of life were included. The study cohort consisted of individuals aged 13-24 diagnosed with ID. The findings consistently highlight the positive relationship between PA interventions and improved health markers in individuals with ID. Diverse PA interventions, ranging from strength training to high-intensity exercises, demonstrated significant improvements in body composition, physical fitness, and bone mineral density. Notably, higher-frequency PA programs (minimum three sessions per week) yielded more substantial benefits. This review underscores the potential of adapted PA interventions to address health concerns and enhance the quality of life for individuals with ID. Further comprehensive research is needed to establish standardized guidelines for effective PA interventions in this population.

Dietary antioxidant capacity is inversely associated with F2- isoprostane and body fat percentage in elite soccer referees

Background Dietary antioxidant Capacity (DaC) has been used as a tool for predicting plasma and dietary antioxidant concentrations. However, the DaC association with oxidative stress (OS) and body composition parameters is an unexplored area, mainly in physically active individuals. Given the potential for increased OS in physically active individuals, it becomes crucial to investigate this association. The aim of this study was to analyze the association between DaC, OS biomarkers, and body composition in healthy and physically active individuals. Methods This Cross-sectional study included 20 male soccer referees. Body composition measurements (body mass, fat mass, lean mass, and waist circumference), OS biomarkers (F2-isoprostane, total antioxidant state, total oxidative status, reduced glutathione, oxidized glutathione, superoxide dismutase, glutathione peroxidase (GPx) and catalase), and DaC were evaluated. Linear regression models were used to determine the association between DaC and the dependent variables. The study was approved by the Human Research Ethics Committee of the Federal University of Santa Catarina (UFSC), CAAE 82584318.0.0000.0121, and file no. 2.572.301. Results DaC was inversely associated with F2-isoprostane (p = 0.044), GPx activity (p = 0.048), and body fat percentage (p = 0.025). Conclusions Increased DaC in physically active individuals may bring benefits related to biomarkers of OS, such as decreasing F2-isoprostane and increasing GPx activity. The increase in DaC also showed an improvement in body composition, demonstrated by the lower percentage of body fat in the study subjects.

A174: Obese Adolescents

Background/Purpose: The incidence of overweight and obesity among adolescents is escalating rapidly. Many studies have validated the efficacy of low-volume, high-intensity interval training (HIIT) in ameliorating cardiometabolic risk factors in individuals with obesity. Nonetheless, the influence of exercise frequency—a pivotal element in HIIT's effectiveness—requires further exploration. This study aimed to evaluate the impacts of different HIIT frequencies on body composition and cardiorespiratory fitness in adolescents aged 10-13 years with obesity. Methods: Sixty adolescents with obesity aged 10-13 (age: 11.0±3.0 years, BMI: 23.4±2.5 kg/m^2) were randomly allocated to three exercise intervention groups (IG1, IG2, and IG3) and a non-exercise control group (CG). The intervention groups engaged in the same running-based HIIT program at varying frequencies: once weekly (IG-1, n=15, 10 males, 5 females), twice weekly (IG-2, n=15, 10 males, 5 females), and thrice weekly (IG-3, n=15, 10 males, 5 females). The CG (n=15, 9 males, 6 females) participated in only regular school physical education and extracurricular activities without additional exercise. Each HIIT session comprised 3 sets of 8 high-intensity 15-second runs at 100% maximal aerobic speed (MAS) and 8 recovery jogs of 15 seconds at 50% MAS, with a 3-minute rest between sets, totaling 18 minutes. Body composition and cardiorespiratory fitness were assessed before and after the intervention. Between-group comparisons were conducted using single-factor ANOVA, and within-group differences were analyzed with paired-samples t-tests. Results: Post a 12-week intervention, all experimental groups exhibited improvements in body composition and cardiopulmonary fitness, notably IG-3 and IG-2, which demonstrated significant enhancements. IG-3 showed significant changes in weight, BMI, body fat percentage, total body fat mass, fat-free mass, VAT, VO2max, systolic blood pressure, and waist circumference (t-values: 8.726, 7.020, 10.960, 4.923, -3.328, 4.948, -10.557, 2.957, 5.113; P &lt; 0.05), as did IG-2 across these metrics (t-values: 8.15, 6.615, 10.831, 5.028, 6.64, -13.705, 2.965, 3.214, 3.453; P &lt; 0.05). Conversely, the CON and IG-1 groups exhibited fewer improvements, with IG-1 showing gains in BMI, FM, BF, FFM, and VO2max (t-values: 3.638, 7.164, 5.551, -3.392, -6.884; P &lt; 0.05). Relative to the control group CG, IG-2 emerged with the most differential indicators post-intervention, followed by IG-3, with IG-1 presenting the least. Conclusion: Running-based high-intensity interval training twice weekly optimally boosts body composition and cardiorespiratory fitness in adolescents with obesity. This frequency balances efficacy and practicality, offering a viable method to combat adolescent obesity. Future research should explore long-term effects and adherence to these exercise regimens.