In situ remediation of cadmium (Cd) and arsenic (As) (Cd&As) contaminated soil using iron-based materials has been extensively investigated. Simultaneous immobilizing Cd&As with iron-based materials while maintaining soil health poses a significant challenge. This study examined the effects of sepiolite-supported nanoscale zero-valent iron (S-nZVI) combined with organic amendments (RS: Rice straw; PM: Pig manure) on Cd&As uptake by rice and soil quality. Grain Cd (0.134mgkg-1) and inorganic As (iAs) (0.099mgkg-1) levels in S-nZVI+PM treatment were reduced by 78.95% and 68.69% compared to CK (P<0.05), and decreased by 52.62% and 17.50% compared to S-nZVI treatment (P<0.05), significantly lower than the Chinese Food Safety Standard (<0.20mgkg-1). The elevated soil pH, increased amorphous iron (Feox), and PM complexation co-contributed to Cd immobilization in S-nZVI+PM treatment; concurrently, the higher Feox maintained lower available As levels in paddy soil. In addition, S-nZVI+PM improved soil fertility, functional enzyme activity, soil bacterial community diversity, and increased brown rice yield. However, S-nZVI+RS facilitated the reductive dissolution of Fe(oxy)(hydro) oxides and As methylation in paddy soil, significantly increasing the total As and organic As content in grains by 113.13% and 236.79%, respectively, compared to S-nZVI treatment. Caution should be exercised in the application of S-nZVI+RS in As-contaminated paddy soil. S-nZVI+PM proved more effective in immobilizing Cd&As and provided greater benefits to soil quality compared to S-nZVI+RS. Overall, S-nZVI+PM represents an eco-friendly approach for alleviating Cd&As accumulation in rice grains while concurrently improving soil health.
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