This study proposes that healthcare delivery can be enhanced by integrating inclusivity and quality improvement (QI) into the inclusivity quality improvement (IQI) framework. This conceptual framework draws on astute theory, including the model for improvement (MFI), the system of profound knowledge (SOPK), the integral inclusivity framework, spiral dynamics, and business theory. Based on the IQI framework, two QI programmes were developed and implemented in the South African healthcare industry to validate, refine, and empirically inform the framework. Case study data were gathered from multiple sources, and content analysis was used to compare the theoretical themes informing the IQI framework. The findings provide insights concerning the theoretical contributions, practical application, prerequisites and barriers to successful QI work in healthcare, and the benefits derived from applying the IQI framework. The findings emphasize that the theories used to inform the framework resulted in improvement, and the applications offered practical insights into QI programme application of value to management. I address the readers directly in the first person, which is increasingly popular using a personal, auto-ethnographic and narrative report style through which I share my thinking and voice with the reader (Berger, 2015; Humphreys, 2005; Hyland, 2002; Onwuegbuzie & Johnson, 2006; Webb, 1992). Keywords: Improvement, Inclusivity, Management, Quality, Case study