Improvements In Cognitive Abilities Research Articles

A Comparison Study of the Auditory P300 Results of Elderly Patients with Sensorineural Hearing Loss

Objective: The purpose of this study was to compare the auditory P300 results of elderly patients with sensorineural hearing loss (SNHL) before and after hearing aid use. Material and Methods: A cross-sectional study was conducted from July, 2016 to April, 2017 at the Hearing Aid Clinic of Ramathibodi Hospital. Twenty-six elderly patients aged ≥60 with bilateral symmetrical SNHL who were referred for unilateral hearing aid fitting by otolaryngologist were included. The auditory P300 was recorded before and 2 months after hearing aid fitting. Results: The P300 waveforms, with a mean latency of 374.48 milliseconds and mean amplitude of 6.68 microvolts (µV), could be recorded in only 21 participants. At 2 months after hearing aid use, the mean P3 latency was 376.83 ms and mean amplitude was 8.77 µV. There was a statistically significant difference in amplitude of P300 2 months after hearing aid fitting (p-value=0.004). Conclusion: The auditory P300 results indicate an improvement in cognitive ability with higher amplitude. Thus, the P300 may be used to evaluate improvements in cognitive function after using a hearing aid. It can also be used as a guideline for explaining the benefits of hearing aid use to patients who initially rejected a hearing aid.

The Mozart effect combined with specific kinetic treatment in patients with Parkinson’s disease

Introduction & objectives: Although controversial, the Mozart effect, consisting of an improvement in cognitive abilities in healthy persons, has started to be studied in the case of patients with various neurological, even neurodegenerative diseases (dementia, treatment-refractory epilepsy). There are few data on the Mozart effect in Parkinson’s disease, but the positive results reported for other neurological pathologies have led us to study this subject. The aim of this study is to compare the results of the Mozart effect associated with specific kinetic treatment in the rehabilitation of Parkinson’s disease and the effect of standard kinesiotherapy, results reflected in the impact on the degree of disability, emotional state and quality of life. Material and method: This was a prospective case-control study, comprising patients with Parkinson’s disease, Hoehn & Yahr stages I-III, included in a motor neurorehabilitation program through the project “The power of hope for patients with Parkinson’s disease” Cluj-Napoca. The patients were assigned to two groups, a control group with specific physiotherapy and the other group receiving the same specific kinetic treatment associated with the Mozart effect, for 2 hours daily, over 14 consecutive days. The patients were assessed using the Schwab & England scale (for the degree of dependence) and the PHQ-9 scale (for depression) before and after therapy. Results: After 2 weeks of therapy, the patients in the study group had much more obvious, statistically significant improvements in both scores. Conclusions: Mozart’s music, as an adjuvant intervention to specific kinetic treatment in patients with Parkinson’s disease, had a beneficial effect, ameliorating the degree of disability and emotional status.

Protective Effects of Hydrolyzed Chicken Extract (Probeptigen®/Cmi-168) on Memory Retention and Brain Oxidative Stress in Senescence-Accelerated Mice.

The senescence-accelerated prone (SAMP8) mouse model shows age-dependent deterioration in learning and memory and increased oxidative stress in the brain. We previously showed that healthy subjects on a six-week supplementation of a chicken meat hydrolysate (ProBeptigen®/CMI-168) demonstrated enhanced and sustained cognitive performance up until two weeks after the termination of supplementation. In this study, we investigate the effect of ProBeptigen on the progression of age-related cognitive decline. Three-month old SAMP8 mice were orally administered different doses of ProBeptigen (150,300 or 600 mg/kg/day) or saline daily for 13 weeks. Following ProBeptigen supplementation, mice showed lower scores of senescence and improved learning and memory in avoidance tasks. ProBeptigen treatment also increased antioxidant enzyme activity and dopamine level while reducing protein and lipid peroxidation and mitochondrial DNA damage in the brain. Microarray analysis of hippocampus revealed several processes that may be involved in the improvement of cognitive ability by ProBeptigen, including heme binding, insulin growth factor (IGF) regulation, carboxylic metabolic process, oxidation–reduction process and endopeptidase inhibition. Genes found to be significantly altered in both ProBeptigen treated male and female mice include Mup1, Mup17, Mup21, Ahsg and Alb. Taken together, these results suggest a potential anti-aging effect of ProBeptigen in alleviating cognitive deficits and promoting the antioxidant defense system.

Sexual selection and the evolution of male and female cognition: A test using experimental evolution in seed beetles.

The mating system is thought to be important in shaping animal intelligence and sexual selection has been depicted as a driver of cognitive evolution, either directly by promoting superior cognitive ability during mate competition, or indirectly via genic capture of sexually selected traits. However, it remains unclear if intensified sexual selection leads to general improvements in cognitive abilities. Here, we evaluated this hypothesis by applying experimental evolution in seed beetles. Replicate lines, maintained for 35 generations of either enforced monogamy (eliminating sexual selection) or polygamy, were challenged to locate and discriminate among mates (male assays) or host seeds (female assays) in a spatial chemosensory learning task. All lines displayed learning between trials. Moreover, polygamous males outperformed monogamous males, providing evidence that sexual selection can lead to the evolution of improved male cognition. However, there were no differences between regimes in rates of male learning, and polygamous females showed no improvement in host search and even signs of reduced learning. Hence, sexual selection increased performance in cognitively demanding mate search, but it did not lead to general increases in cognitive abilities. We discuss the possibility that sexually antagonistic selection is an important factor maintaining abundant genetic variation in cognitive traits.

Effect of Exercise Interventions on Kainate Induced Status Epilepticus and Associated Co-morbidities; A Systematic Review and Meta-Analysis

To conduct a systematic review and meta-analysis of studies testing the effect of exercise in Kainic-acid (KA) induced status-epilepticus (SE) and to quantify the efficacy of exercise strategies in the prognosis of SE and co-morbidities. Two authors searched online databases (Pubmed and Web of Science) independently for studies testing the efficacy of exercise programs in KA-induced SE models. Reviewers autonomously extracted data on models used, exercise interventions and prognosis in all reported outcomes (behavioral, histological, biochemical and cognitive outcomes). All studies were summarized and relevant outcomes' data were pooled by means of a meta-analysis. Among 14 selected studies; Quantitative analysis of studies with pre-SE exercise interventions showed significant reduction in mortality rate among 76 animals of four studies (RR = 0.57, [95% CI 0.34, 0.95], p = 0.03, I2 = 57%) and seizure rating score among three studies (n = 56) with MD = - 1.04, [95% CI - 2.07, - 0.00], p = 0.05, I2 = 71%. Three studies (n = 62) presented with improved anti-oxidant enzymes' profile (SMD = 0.75, [95% CI 0.55, 2.31], p = 0.0008, I2 = 44%) as a result of exercise intervention. Same intervention failed to show any significant measure for BDNF level and neuroprotection assessed through neuronal number in different brain areas with MD = - 1.22, [95% CI - 136.66, 134.22], p = 0.99, I2 = 0% and SMD = - 0.05, [95% CI - 0.62, 0.52], p = 0.86, I2 = 61% respectively. Qualitative review concluded in the reduction of median seizure score, depression and anxiety-like behaviors with improved cognitive performances in pre-SE exercised animals while improved memory and learning capabilities with increased neurogenesis were observed in post-SE exercised models. Exercise before SE reduces behavioral seizures and oxidative stress with improvements in cognitive abilities. Post-SE exercise enhances learning and memory with neurogenesis in KA models. More extensive research on morphological and biochemical profiles is needed to explore underlying mechanisms.

Cytotoxic Withanolides from the Roots of Indian Ginseng ( Withania somnifera).

Withania somnifera, commonly known as "Indian ginseng" or "ashwagandha", is popular as a functional food because of its diverse purported therapeutic efficacies including invigorating, improvement of cognitive ability, and stress release activities. Chemical investigation of the MeOH extract of W. somnifera roots combined with LC/MS-based analysis resulted in the identification of six new withanolides, withasilolides A-F (1-6), as well as seven known compounds (7-13). The structures of the new compounds were established by application of spectroscopic methods, including 1D and 2D NMR, HRMS, and ECD measurements. The cytotoxicity of the isolated compounds was evaluated against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15). Compounds 1, 2, 4, 6, and withanone (11) each showed cytotoxicity for one or more of the four cancer cell lines used.

Intervention Comparative Effectiveness for Adult Cognitive Training (ICE-ACT) Trial: Rationale, design, and baseline characteristics

Age-related perceptual and cognitive declines are associated with difficulties performing everyday tasks required to remain independent. Encouraging improvements in cognitive abilities have been shown for various short-term interventions but there is little evidence for direct impact on independence. This project compares the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving and fraud avoidance. Participants (N = 230, Mean age = 72) were randomly assigned to one of four training conditions: broad training using either (1) a web-based brain game suite, Brain HQ, or (2) a strategy video game, Rise of Nations, or to directed training for (3) Instrumental Activities of Daily Living (IADL) training using web-based programs for both driving and fraud avoidance training, or (4) to an active control condition of puzzle solving. Training took approximately 15–20 h for each intervention condition across four weeks. Before training began, participants received baseline ability tests of perception, attention, memory, cognition, and IADL, including a driving simulator test for hazard perception, and a financial fraud recognition test. They were tested again on these measures following training completion (post-test). A one-year follow-up from training completion is also scheduled. The baseline results support that randomization was successful across the intervention conditions. We discuss challenges and potential solutions for using technology-based interventions with older adults. We also discuss how the current trial addressed methodological limitations of previous intervention studies. Trial registration numberNCT03141281

Implementing Cognitive Strategy Instruction to Improve the Actual Intellectual Abilities of the Undergraduate Students with Cognitive Expression Difficulties

This research aims to find out the effectiveness of cognitive strategy instruction for improving intellectual abilities of undergraduate students with cognitive expressing difficulties, especially in actualizing their thinking abilities starting from lower order thinking up to higher order thinking. Therefore, the cognitive strategy instructional design based on Bloom’s Taxonomy is constructed in order to accomplish the research objectives. This research uses mixed method approach entailing the implementation of two research methods. The first is qualitative method which aims to get information of the cognitive strategy in instructional process. The second is quantitative method which is used to measure the students’ improvement in cognitive abilities or actual intellectual abilities after participating in cognitive strategies instruction. Research implementation is divided into three stages. The first stage is needs assessment, in which the students’ thinking / cognitive skill abilities are observed and measured in order to have evidence whether or not they have cognitive expression difficulties. The second stage is to use the needs assessment results in designing cognitive strategy instruction. The third stage is the implementation of the instructional design. There are 20 undergraduate students taking part in this research who are selected by purposive sampling technique. The results revealed that cognitive strategy instruction effectively improves the actual intellectual abilities of students with cognitive expression difficulties. Qualitatively, the students feel very satisfied with their actual intellectual abilities.

КОГНІТИВНИЙ ПІДХІД ДО ЗБІЛЬШЕННЯ ПІЗНАВАЛЬНИХ РЕСУРСІВ ТА ПОКРАЩЕННЯ РОЗУМОВОЇ ДІЯЛЬНОСТІ ЛІТНЬОЇ ЛЮДИНИ

Urgency of the research. In terms of increasing the duration of human life and the aging of the population around the world, it is relevant to study the features of the mental activity of the elderly in order to improve it. Target setting. With age, the risk of dangerous brain diseases with various forms of senile dementia increases. Learning to restore brain cells, reprogram the brain, preventing rapid aging is extremely important. Actual scientific researches and issues analysis. Important postulates for the study of cognitive features of the elderly were the statements of S. Freud, K. Jung, A. Adler. Uninvestigated parts of general matters defining. Ideas of S. Freud, K. Jung, A. Adler not enough used in scientific gerontology. The research objective. The purpose of this article is to reveal the essence of the cognitive approach to the development of the personality of elderly, increase cognitive resources, and improve their mental activity. The statement of basic materials. When diagnosing cognitive processes, the levels of intelligence "fluid" (innate inclinations and abilities) and "crystallized" (acquired knowledge, skills, and abilities of cognitive activity) appear. with constant mental activity in old age the last one does not deteriorate, but on the contrary increases, is characterized by a sufficient level of general education, awareness, relies on experience, and is closely related to wisdom. Conclusions. Cognitive-behavioral approaches should be used for therapeutic purposes in the treatment of cognitive disorders among the elderly (elimination/reduction of symptoms of brain disease, prevention of relapses, improving the effectiveness of drug treatment), as well as the development and improvement of cognitive abilities. The latter requires a change in psychological attitudes, thoughts, attitudes to life, the formation of positive behavioral patterns.

Fighting Against Learning Crisis in Developing Countries: A Randomized Experiment of Self-Learning at the Right Level

This paper investigates the effectiveness of a globally popular method of self-learning at the right level in improving learning outcomes—the cog- nitive and non-cognitive abilities of disadvantaged pupils—in a developing country, Bangladesh. Using a randomized control trial design, we find sub- stantial improvements in cognitive abilities measured by mathematics test scores and catch-up effects on aspects of non-cognitive abilities or person- ality traits measured by a self-esteem scale. We also find a longer-term impact on cognitive abilities regarding the math scores students obtained on national-level exams compared to the baseline test scores. Moreover, teachers’ abilities to assess students’ performance substantially improve. Our estimates indicate that the program’s benefits exceed its costs. The above findings suggest that self-learning at the right level can effectively supplement the quality of primary education and hence address the learn- ing crisis in developing countries.

Auditory P300 in Elderly with Sensorineural Hearing Loss

Background: Hearing loss and cognitive impairment are common problems in older adults; several studies were conducted on the effects of hearing aid use relative to cognitive function in older adults. Most studies only used a verbal questionnaire which could lead to biased results. Therefore, the auditory P300 response from an electrophysiologic test provides an objective measure of central auditory function, including the cognitive process in the brain. Methodology: A cross-sectional study was conducted from July, 2016 to April, 2017 at The Hearing Aid Clinic in Ramathibodi Hospital. Participants were 26 elderly patients with bilateral symmetrical sensorineural hearing loss who were referred for unilateral hearing aid fitting by ENT doctors. The auditory P300 test results and MMSE-Thai scores were recorded before and 2 months after hearing aid fitting. Results: The P300 waveforms could be recorded from only 21 participants with a mean latency of 374.48 ms and mean amplitude of 6.68 μV. Two months after hearing aids were used, the mean P3 latency was 376.83 ms and the mean amplitude was 8.77 μV. There was a statistically significant difference in the amplitudes of P3 2 months after HA fitting (p=0.004). Moreover, the MMSE-Thai scores were also significantly higher (p=0.000). Conclusion: The auditory P300 components could be recorded from approximately 80% of the sensorineural hearing loss elderly patients in this study. The auditory P300 results showed an improvement in cognitive ability with higher amplitude, corresponding to an increase in MMSE-Thai scores. Thus, the P300 may be used to evaluate the improvement in cognitive function after using a hearing aid. This outcome can be a guideline in counseling patients who initially rejected hearing aids on the benefits of using the hearing aids.

IMPLEMENTASI MOBILE LEARNING DENGAN MODEL ADVANCE ORGANIZER DALAM MENINGKATKAN KEMAMPUAN KOGNITIF KIMIA MAHASISWA

The use of internet-based information technology on computers in the information network that is learned through cellular technology, cellular-based applications is easier to use the material provided by lecturers, the presence of mobile learning technology becomes a liaison between students and lecturers in learning, with mobile technology becoming a new alternative in providing learning content / items that are more innovative and dynamic. This study uses qualitative data relating to the questionnaire by looking at the feasibility of mobile learning media that contains relevant indicators on the National Education Standards Agency and quantitative data to determine the results of the effectiveness of mobile learning with advanced organizer models in improving chemical cognitive abilities. this is all study program pharmacy Efarina university students. Data collection is done by objective tests for student learning outcomes. Data were analyzed using SPSS 17.0 with a significant level of 0.05. The results of the study are in the form of mean validation to determine whether or not the media of mobile learning is feasible. The results obtained: (1) The composition of the material / media framework on mobile learning media is feasible and in accordance with the Curriculum (2) Mobile learning media developed for the pharmacy study program in the first semester class is feasible to use the results of standardization 3.58, standardization of language feasibility 3.66, standardization of presentation feasibility of 3.72, graphic standardization of 3.69 (3) is certainly the result that is significant improvement in cognitive abilities of students with the implementation of mobile learning with advance organizer models (Sig.1-tailed <α (0.0285 <0.05)).

DNA barcoding of species of Bacopa coupled with high-resolution melting analysis.

In Thailand, there are three species of Bacopa, namely, B. monnieri, B. caroliniana, and B. floribunda. Among these species of Bacopa, B. monnieri is the only medicinal species, used for the treatment of cognitive impairment and improvement of cognitive abilities because of its bioactive constituents, bacoside A and B. However, because of the similar characteristics of these species, it is difficult to differentiate among related species, resulting in confusion during identification. For this reason, and to ensure therapeutic quality for consumers, authentication is important. In this study, the three abovementioned species of Bacopa were evaluated using barcoding coupled with high-resolution melting (Bar-HRM) analysis based on primers designed for the trnL-F sequences of the three species. The melting profiles of the trnL-F amplicons of B. caroliniana and B. floribunda were clearly different from the melting profile of the trnL-F amplicon from B. monnieri; thus, the species could be discriminated by Bar-HRM analysis. Bar-HRM was then used to authenticate commercial products in various forms. The melting curves of the six commercial samples indicated that all the tested products contained genuine B. monnieri species. This method provides an efficient and reliable authentication system for future commercial herbal products and offers a reference system for quality control.

Application of Learning Model (LC) 7E with Technology Based Constructivist Teaching (TBCT) and Constructivist Teaching (CT) Approach as Efforts to Improve Student Cognitive Ability in Static Fluid Concepts

This study aims to get a representation of the students’ cognitive abilities improvement on the concept of static fluid as a result of the application of learning cycle 7E with Technology Based Constructivist Teaching (TBCT). This research uses quasi experiment method with Pre-test Post-test Two Equivalent Group Design. The subjects were class XI students of academic year 2017-2018 as many as 56 students divided into 2 classes, 29 students of class XI IPA 1 as experimental class and 27 students of class XI IPA 2 as control class. Measurement of students’ cognitive abilities used a multiple choice instrument test on the concept of static fluid. The data were collected using pre-test and post-test. The results showed that the learning of physics with learning model LC 7E with TBCT approach can significantly improve students’ cognitive abilities on the concept of static fluid with n-gain value of 0.56 categorized medium compared to physics learning with learning model LC 7E with CT approach with n-gain value of 0.51 categorised medium. Hypothesis test results showed that there were no significant differences in students’ cognitive abilities on the static fluid concept between students who received learning model LC 7E with TBCT approach with students who received learning model LC 7E with CT approach with a significance value of 0,217. Although there were no significant differences, the improvement in cognitive abilities of students in the experimental class was high compared to the control class.

Funkcja widzenia po obuocznym wszczepieniu wtórnym soczewki, wykonanym 18 lat po usunięciu zaćmy wrodzonej u pacjenta z zespołem różyczki wrodzonej

Comparison of a quality of vision and changes in a everyday function in 18 years old patient with congenital rubella syndrome and concomitant nystagmus who was undergoing onetime secondary implantation of intraocular lenses. A congenital cataract extraction has been done in the first years of his life. An eye defect of high hyperopia was a consequence of postoperative aphakia and has never been corrected before. A lack of cooperation from the patient was a consequence of mental retardation. Secondary lens implantations have been done to the sulcus, onetime to the both eyes. The procedure was done under total anaesthesia. An electrophysiology examinations were taken before and 24 months after the surgery. A total change in behavior and also an improvement of cognitive abilities which was accompanied by retinal response observed in electrophysiology examinations has been achieved after correction of high hyperopia by secondary lens implantation gained due to correction of both eyes. Correction of high hyperopia caused by postoperative aphakia after removal of congenital cataract resulted in improvement of vision quality, despite long-term, over ten years of absence of any correction of this defect. Obtaining this improvement effect should be an incentive to consider secondary implantation in every case, especially when the other senses (hearing) and communication organs (speech) are also disturbed, regardless of the period of non-correction.

Resilience after a neurological pathology: What impact on the cognitive abilities of patients with brain damage?

ABSTRACTThe aim of this study is to examine resilience in patients with traumatic brain injury and patients who suffered from stroke. As traumatic brain injury and stroke both have a recovery potential, we investigate cognitive recovery in this context. Given the involvement of resilience in physiological recovery and positive emotions in enhancing cognitive capacities, we hypothesised that resilience could be related to cognitive abilities and recovery following traumatic brain injury and stroke. Our results show the same degree of resilience and cognitive capacities in our participants in two separate assessments. An improvement in cognitive abilities was observed, as was a correlation between these abilities and resilience. In other words, the greater the resilience, the higher the patient’s cognitive performances. Resilience appears to influence cognitive abilities in participants with brain damage and also be involved in recovery.

Interdisciplinary Learning and Linguistic Development in an ICT-based Collaborative Videoconferencing

Much research has shown that telecollaboration helps language learners not only improve their linguistic skills but also further their intercultural competence. This research, though, primarily focuses on the English and European languages. Given a paucity of Internet-mediated communication (IMC) studies on less commonly taught languages, this paper explores and describes the interactions between Korean language learners and English language learners in information and communications technology (ICT)-based collaborative videoconferencing, which was aimed at improving interdisciplinarity and linguistic skills. Specifically, it reports on the ten-week synchronous interactions of one-to-one desktop videoconferencing having a series of sessions arranged between 15 intermediate-level Korean learners at a US university and their counterparts in South Korea. The results show that the one-on-one ICT-based videoconferencing enhances Korean-English language learners’ interdisciplinary learning and linguistic skills in terms of increased recognition of bias, improvement of cognitive abilities and critical thinking skills, as well as deepening the understanding of lexical items and sentence-level expressions.

Improvement in cognitive abilities following cabergoline treatment in patients with a prolactin-secreting pituitary adenoma.

Hyperprolactinaemia may affect sexual and reproductive functioning. However, recent studies suggest that increased prolactin levels may also have negative effects on cognition. We aimed to study whether the reduction in prolactin levels by cabergoline in patients with hyperprolactinaemia is followed by an improvement in cognitive tasks. We studied seven patients with hyperprolactinaemia caused by a prolactinoma that had an indication to start treatment with cabergoline. All patients were assessed twice (baseline and 6-12 months after cabergoline treatment) with a cognitive battery. Plasma prolactin levels were determined. We found a significant improvement in the speed of processing, working memory, visual learning and reasoning and problem-solving domains after cabergoline treatment. Improvements in speed of processing and reasoning and problem solving were greater in patients with baseline prolactin levels above the median. In summary, a reduction in prolactin levels by cabergoline in patients with hyperprolactinaemia is followed by an improvement in cognitive abilities. This finding suggests that prolactin may be involved in cognitive processes, although cabergoline could also have procognitive effects that are independent of prolactin changes. Further clinical trials are needed to confirm the potential cognitive-enhancement properties of cabergoline in patients with chronic hyperprolactinaemia.

Does playing video games effect cognitive abilities in Pakistani children?

Objective:To find out the effect of playing video games on cognitive abilities among teenagers.Methods:A comparative cross sectional study was conducted at two schools in Rawalpindi from August 2014 till February 2015. A sample size of 171 was calculated by using WHO sample size calculator using non-probability convenient sampling technique. A mixed questionnaire was used as a data collection tool and two groups were defined as video gamers and non-video gamers. Video gamers were those students who were using video games for two hours or more. Cognitive ability of the students were assess by standardized questionnaire named Wonderlic Cognitive Ability Test Questionnaire. Data were entered and analyzed in SPSS version 20.Results:There were 93 (54.4%) gamers whereas 78(45.4%) were non-gamers. Mean age of the participants was 18.86+1.46 years. Gamers with correct answers to knowledge, analogy, processing speed, deductive reasoning, mathematical intelligence were 57(61.3%), 67(72%), 68 (73%), 58 (62.4%) and 73(78.5%) respectively. Significant association was found between gamer status and gender (p=0.023), analogy (p=0.049), processing speed (p<0.001), deductive reasoning (p=0.003) and mathematical intelligence (p<0.001). There was no significant association of gamer status with knowledge (p=0.188).Conclusion:Gamers exhibit better range of cognitive abilities specifically involving analogy, processing speed, deductive reasoning and mathematical intelligence. In this study, those who play video games on long term basis, showed improvement in cognitive abilities, in comparison to those who do not indulge in gaming activities.

GUIDED INQUIRY AND GUIDED DISCOVERY MODEL IN SCIENCE LEARNING TO ‎IMPROVE COGNITIVE ABILITY OF JUNIOR HIGH SCHOOL STUDENTS

This study aims to find out the improvement of cognitive ability through the implementation of guided inquiry and guided discovery model in integrated natural science learning. Alternative energy sources was chosen as the learning theme which contain Biology, Physic, Chemistry concepts, which consist of briquettes as the heat source, and battery as the power source. This study used quasi experiment method with matching only pretest posttest control group design. The subject of this study were 42 students of VII grade of Junior High School in Kampar District which consist of experiment and control class with 21 students in each class. Student cognitive learning outcomes was measured by multiple choice test instrument, which contain of 21 items which was done twice (pretest and posttest). The technic of data analysis was normality test and hypothesis test (U test). Data were analyzed by IBM SPSS 22 statistics and Microsoft Excel 2010 program. The N-Gain average of cognitive ability shows that there is an improvement of student cognitive ability in experiment class as 0,44 with intermediate category, and in control class as 0,21 with low category. While, the result of U test toward N-Gain value shows that there is a significant difference on student cognitive ability between students in experiment and control class. Thus, it can be concluded that guided inquiry model can improve student cognitive ability more than guided discovery model. Keywords: guided inquiry model, discovery guided model, cognitive ability, alternative energy sources