The prolonged sedentary nature of office work has been shown to induce high levels of discomfort, leading to decreased worker productivity. Many modalities, including ergonomic-adjustable chairs, treadmill desks, and light-activity promotion have been used as interventions to combat worker distress and productivity. The sit-to-stand (STS) workstation is another tool aimed at improving workers’ focus and productivity. PURPOSE: Therefore, the purpose of this study is to evaluate the efficacy of a STS workstation on work productivity. METHODS: All participants were volunteer faculty and staff of the University of Central Oklahoma randomly assigned to a control (n= 10) or STS workstation intervention (n= 8) group. Both groups filled out the Health and Work Performance Questionnaire at the base-line, 6-month, and 12-month mark of the study to measure productivity. Absolute productivity is a subjective measure of an employee's work output. Relative productivity is a subjective comparison of the employee’s work output to another employee in a similar position. The control group was instructed to continue their day as normal while the intervention group was instructed to stand at least 2 hours per work day, if possible. RESULTS: There was no interaction effect for absolute productivity (F2,15=.91, p=.42) from baseline to 12 months with a moderate effect size (0.68). However, a decrease was seen in the control group from baseline (85 +/- 7.07) to post-test (73.08 +/- 28.07) with a strong effect size (1.69), while the STS workstation group increased from baseline (86.25 +/- .88) to post-test (88.75 +/- 8.35). Relative productivity showed no interaction effect as well (F2,15 = .89, p = .44) from baseline to 12 months. The control group saw a decrease from start (1.09 +/- .17) to finish (1.07 +/- .10) while the intervention group saw an increase from start (1.10 +/- .12) to finish (1.19 +/- .26). CONCLUSIONS: Overall, the STS workstation did not show a significant improvement in work productivity compared to the control group. However, a positive trend was seen in the intervention group towards perceived greater work production. ACKNOWLEDGEMENTS: This study was funded by the University of Central Oklahoma, Research and Sponsored Programs office and Areawide Aging Agency.