Important Value Research Articles

Citric Acid Loaded Hydrogel-Coated Stent for Dissolving Pancreatic Duct Calculi.

In recent years, the incidence of chronic pancreatitis has increased significantly. Pancreatic calculi obstruct the pancreatic duct and induce abdominal pain in the patients. Pancreatic duct stenting is the major treatment option for chronic pancreatitis with calculi. In this study, a new kind of drug-eluting stent, a pancreatic stent coated by methacrylated gelatin (GelMA) hydrogel loaded with citric acid (CA), was designed for the interventional treatment of pancreatic duct calculi. The CA loading capacity reached up to 0.7 g CA/g hydrogel-coated stent. The GelMA hydrogel coating has higher mechanical strength and lower swelling performance after loading with CA. The in vitro experiments of stents exhibited good performance in CA sustained release and the calculi can be dissolved in almost 3 days. The stents also showed good blood compatibility and cell compatibility. This research has important clinical value in the treatment of chronic pancreatitis with pancreatic calculi.

Morphological and anatomical studies of Ocimum basilicum L. cultivated in Al-Marj city, Libya

Ocimum basilicum L. belonging to the Lamiaceae family known as the ‘King of Herbs has been used as traditional medicine for various ailments. The aim of the present study is to provide new properties for the identification and description of this species. The morphological and anatomical patterns were investigated by light microscope. The features of floral morphology such as verticillaster number, bract, calyx, corolla and stamens are important characters to distinguish this species. The stomata are present in both epidermises, being of diacytic and anisocytic types. Vascular supply of stem consists of four arcs while in leaves and petiole are continuous bundles. Mesophyll dorsiventral of one row of rectangular palsiade tissue adaxially followed rows of spongy tissue. We observe morphologically different types of glandular and non-glandular trichomes in all the studied organs. The different morphological characters in the trichomes have very important taxonomic values.

Mining of disease-resistance genes in Crocus sativus based on transcriptome sequencing.

Introduction: Crocus sativus L. has an important medicinal and economic value in traditional perennial Chinese medicine. However, due to its unique growth characteristics, during cultivation it is highly susceptible to disease. The absence of effective resistance genes restricts us to breed new resistant varieties of C. sativus. Methods: In present study, comprehensive transcriptome sequencing was introduced to explore the disease resistance of the candidate gene in healthy and corm rot-infected C. sativus. Results and discussion: Totally, 43.72Gb of clean data was obtained from the assembly to generate 65,337 unigenes. By comparing the gene expression levels, 7,575 differentially expressed genes (DEGs) were primarily screened. A majority of the DEGs were completely in charge of defense and metabolism, and 152 of them were annotated as pathogen recognition genes (PRGs) based on the PGRdb dataset. The expression of some transcription factors including NAC, MYB, and WRKY members, changed significantly based on the dataset of transcriptome sequencing. Therefore, this study provides us some valuable information for exploring candidate genes involved in the disease resistance in C. sativus.

Use of outcome measures by UK allied health professionals: a cross-sectional online survey

Background/Aims Outcome measures are key tool for assessing the effects of healthcare on health status, but little is currently known about their use by allied health professionals in the UK. This study aims to explore the use of outcome measures by allied health professionals, with a view to informing future research and developing clinical training resources. Methods An online survey regarding use of outcome measure was developed, including 28 questions covering demographic and professional characteristics, frequency of use of outcome measures, perceptions of and barriers to use and confidence in use. The survey was distributed to UK allied health professionals by contacting relevant professional bodies and using social media. Comparisons between groups were made with the Mann-Whitney U test, Chi square or comparisons of column means. Significance was set at 0.05. Results Responses from 107 allied health professionals were analysed, representing 13 of the 14 allied health professional groups across the UK. Most respondents (85%) used outcome measures, with 37% reporting frequency of use as ‘always’ and 33% as ‘often’. Most respondents (75%) used informal approaches to interpret outcome measure data, while 17% used normative data and 15% used minimal clinically important difference values. The most commonly reported barriers were lack of time (70%), administrative support (47%), resources (41%) and training (35%). Levels of pre-registration and post-registration training in outcome measures were low (28% and 56% respectively). Postgraduate training in outcome measures was significantly associated with frequent use of outcome measures (P=0.010). Conclusions Most UK allied health professionals use outcome measures regularly, but few use formal approaches to interpret the data collected. This study highlights a need for training for pre-registration and post-registration allied health professionals in the use of outcome measures.

Assessment of species diversity, biomass and carbon stock of mangrove forests on Belitung Island, Indonesia

Abstract. Henri, Farhaby AM, Supratman O, Adi W, Febrianto S. 2023. Assessment of species diversity, biomass and carbon stock of mangrove forests on Belitung Island, Indonesia. Biodiversitas 24: 6761-6769. Mangroves are highly productive ecosystems that provide important ecosystem services for people and nature, including climate change mitigation. This study analyzed species diversity, biomass value, and estimated carbon stocks in mangrove forest ecosystems on Belitung Island, Indonesia. The data collection method is carried out by creating a linear plot consisting of several circular subplots. Data analysis was carried out to determine the frequency, density, important value index, biomass (above-ground and below-ground biomass), and carbon content. The results of research on mangrove ecosystems on Belitung Island obtained ten species of mangroves dominated by Rhizophora apiculata Blume found in all research sites. The density of mangroves in the four locations (>1,500 trees/ha) is very dense. In contrast, the location in Juru Seberang (1,349 trees/ha) is categorized as moderate because it is the location of previous reforestation. Rhizophora apiculata has an important value index at the tree (161.24%) and sapling (149.24%) levels. Mangroves on Belitung Island have a total biomass value (225.08 t ha-1), estimated carbon content (112.54 t C ha-1), and carbon dioxide (CO2) absorption of 413.02 t CO2 ha-1. Sustainable coastal ecosystem management can significantly reduce carbon emissions from the land use sector and maintain ecosystem services in these coastal habitats, considering Belitung Island as one of the archipelago areas.

The impact of preferential market access: British imports into Canada, 1892–1903

AbstractCanada initiated the formation of the (modern) imperial trade bloc in 1897 when it extended preferential market access to imports from Britain. British goods initially received a preferential reduction of one eighth of the applicable duty, rising to one quarter in 1898 and one third in 1900. Because duties varied across imported commodities, the uniform relative margins of preference resulted in cross‐commodity variation in the absolute margins of preference. This cross‐commodity variation is exploited in our paper. Relying on a data set that includes over 32,000 Canadian import products, we find that a 1 percentage‐point increase in the absolute margin of preference was associated with a 5.4% increase in the value of imports from Britain. Counterfactually, if Canada had not adopted a preferential trade policy, by 1903, the value of British imports into Canada would have been reduced by approximately one half.

Practical research on accounting teaching innovation in digital enabling universities

This paper deeply investigates the theoretical framework, practical methods, case studies, effect evaluation, challenges, and countermeasures of digital empowerment in accounting education in universities. The research finds that digital empowerment in accounting education in universities has important theoretical and practical value, and it is of great significance for improving teaching quality and cultivating students’ practical ability. However, we should also realize that digital empowerment in accounting education still faces some challenges, such as how to protect students’ privacy and how to ensure teaching quality. Therefore, we need to continue to explore and research in order to better utilize digital empowerment in accounting education.

The relationship of fat and muscle measurements with emphysema and bronchial wall thickening in smokers.

Differences in body composition in patients with COPD may have important prognostic value and may provide opportunities for patient-specific management. We investigated the relation of thoracic fat and muscle with computed tomography (CT)-measured emphysema and bronchial wall thickening. Low-dose baseline chest CT scans from 1031 male lung cancer screening participants from one site were quantified for emphysema, bronchial wall thickening, subcutaneous fat, visceral fat and skeletal muscle. Body composition measurements were performed by segmenting the first slice above the aortic arch using Hounsfield unit thresholds with region growing and manual corrections. COPD presence and severity were evaluated with pre-bronchodilator spirometry testing. Participants had a median age of 61.5 years (58.6-65.6, 25th-75th percentile) and median number of 38.0 pack-years (28.0-49.5); 549 (53.2%) were current smokers. Overall, 396 (38.4%) had COPD (256 Global Initiative for Chronic Obstructive Lung Disease (GOLD) 1, 140 GOLD 2-3). Participants with COPD had less subcutaneous fat, visceral fat and skeletal muscle (p<0.001 for all). With increasing GOLD stages, subcutaneous (p=0.005) and visceral fat values (p=0.004) were higher, and skeletal muscle was lower (p=0.004). With increasing severity of CT-derived emphysema, subcutaneous fat, visceral fat and skeletal muscle values were lower (p<0.001 for all). With increasing CT-derived bronchial wall thickness, subcutaneous and visceral fat values were higher (p<0.001 for both), without difference in skeletal muscle. All statistical relationships remained when adjusted for age, pack-years and smoking status. COPD presence and emphysema severity are associated with smaller amounts of thoracic fat and muscle, whereas bronchial wall thickening is associated with fat accumulation.

Study of Sociological Aspects of Traditional Medicine in Inland Communities in West Java, Indonesia

Traditional medicine is a form of health service that has existed for a long time in Indonesia. Traditional medicine is still used by some people, especially people in rural areas. This research aims to examine the sociological aspects of traditional medicine in rural communities in West Java, Indonesia. This research uses a qualitative method with a case study approach. The research informants consisted of 10 people who were traditional medicine practitioners and people who used traditional medicine. Data was collected through in-depth interviews and observations. The results of the research show that traditional medicine in rural communities in West Java, Indonesia, has an important role in people's lives. Traditional medicine is used to treat various diseases, both physical and non-physical. Traditional medicine is also used to maintain health and improve people's quality of life. The discussion shows that traditional medicine has important social values for the people of inland West Java, Indonesia. These social values include the value of togetherness, the value of local wisdom, and the value of solidarity. Traditional medicine also plays a role in strengthening the cultural identity of the people of inland West Java, Indonesia. The research conclusion shows that traditional medicine is an inseparable part of the lives of the people in the interior of West Java, Indonesia. Traditional medicine has an important role in social, cultural, and public health aspects.&#x0D;

Exploring microscopic pollen morphology in herbaceous Flora: Insights and analysis using scanning electron microscopy.

Microscopic techniques can be applied to solve taxonomic problems in the field of plant systematic and are extremely versatile in nature. This study was focused on the new approaches to visualizing the imaging, tool to cover the micro-structural techniques applied to the pollen study of flowers. The current research was proposed to evaluate microscopic pollen morphological attributes using light and scanning electron microscopy of herbaceous flora from Samarkand, Uzbekistan. A total of 13 herbaceous species, classified into 11 different families were collected, pressed, and identified, and then acetolyzed their pollen to visualize under light and scanning electron microscopy. Herbaceous flora can be characterized by small to very large-sized pollen morphotypes presenting four types of pollen shapes, prolate spheroidal (six species), spheroidal (three species) and prolate and oblate (two species each). The polar diameter and equatorial distance were calculated maximum in Hibiscus syriacus 110.55 and 111.2 μm respectively. Pollen of six different types was found namely tricolporate pollen observed in seven species, tricolpate and pantoporate in two species each, sulcate in Gagea olgae and hexacolpate pollen was examined in Salvia rosmarinus. Exine ornamentation of pollen was examined tectate perforate, verrucate-reticulate, micro-reticulate, reticulate, reticulate-cristatum, gemmate-echinate, echinate-perforate, perforate-striate, rugulate, rugulate-striate, bi-reticulate, reticulate-perforate and perforate-micro-reticulate showing great variations. Exine thickness was noted highest for Rosa canina 2.9 μm and minimum in Punica granatum 0.65 μm. This study of pollen imaging visualization of herbaceous flora contributes to the opportunity for the taxonomic evaluation of and fills knowledge gaps in studies of herbaceous flora identification using classical microscopic taxonomic tools for their accurate identification. RESEARCH HIGHLIGHTS: Pollen in unexplored herbaceous flora of the Samarkand region was studied with light and scanning electron microscopic pollen study. There is a high variation in observed pollen micromorphological characters. Pollen microscopic morphology has important taxonomic value for the identification of herbaceous species.

The Technical and Aesthetic Characteristics of The Pirouette as Applied in Classical Dance

As the core part of technical training, rotation skill has a very important training value and status. "Spin" is one of the most important kinds of Chinese classical dance technique, as the Chinese classical dance teaching training content and the teaching material system, in constant teaching practice, Chinese classical dance rotation technology from single to diversified development, and gradually in the teaching and training show a unique aesthetic attributes and style. In the training of technical skills of Chinese classical dance, "the technology of body rhyme, technology and rhyme" and "training body with body" are the main thoughts, which run through the teaching of Chinese classical dance, and accurately interpret the needs of aesthetic and style characteristics of Chinese classical dance culture. In the classical dance teaching, the rotation skills are more difficult. Through the research of this paper, we can provide new ideas and directions for teaching, and help teachers to form new teaching thinking and teaching methods. Secondly, the study in this paper can deepen the understanding and understanding of teachers and students on the rotation skills in dance, guide students to establish correct thinking and learning attitude, which is conducive to obtaining an ideal learning effect and improving the level of classical dance.

Analysis of Mutational Status of IGHV, and Cytokine Polymorphisms as Prognostic Factors in Chronic Lymphocytic Leukemia: The Romanian Experience.

The aim of the current study was to assess the associations between genetic risk factors (such as the mutational status of the IGHV gene and polymorphisms of the IL-10 and TNF-α genes) and CLL risk, prognosis, and overall survival. Another goal of this study was to evaluate the multivariate effect of the combination of multiple genetic risk factors (mutational status of the IGHV gene, somatic mutations, DNA CNVs, and cytokine SNPs) on the clinical characteristics and survival of patients. A total of 125 CLL patients and 239 healthy controls were included for comparative SNP analysis. IL-10 (rs1800896 and rs1800872) and TNF-α (rs361525 and rs1800750) SNPs and haplotypes were not associated with CLL risk. The absence of hypermutation in the IGHV gene was shown to be of important prognostic value, being associated with short OS. Further individual risk factors for short OS were an age above 65 years at diagnosis and the presence of somatic mutations and/or CNVs. In our multivariable analysis, the presence of somatic mutations and the IL-10 rs1800872 variant allele, and the association of CNVs with the IL-10 rs1800896 variant allele, were identified as risk factors for short OS. Moreover, the OS in unmutated IGHV patients was additionally affected (decreased) by the presence of CNVs and/or somatic mutations. Similarly, IL-10 rs1800896 modulated the OS in unmutated IGHV patients with CNVs.

Integrated transcriptome and small RNA sequencing revealing miRNA-mediated regulatory network of bicolour pattern formation in Pericallis hybrida ray florets

Flower spots of plants are of evolutionary importance and ornamental value, but research on regulatory mechanisms is still limited. Cineraria (Pericallis hybrida) is an important ornamental plant with various bicolour cultivars. In this study, we performed transcriptome and small RNA sequencing to investigate the regulatory network of bicolour pattern formation in P. hybrida ray florets. Through transcriptome sequencing, we mainly focused on differentially expressed genes (DEGs) involved in flavonoid biosynthesis. Gene expression analysis showed that PhLAR (Unigene0092951), PhMYB8 (Unigene0068595) and PhbHLH137 (Unigene0091507) were up-regulated in the colourless region. Additionally, we identified 234 known miRNAs and 280 novel miRNAs by sRNA sequencing, and 49 differentially expressed miRNAs (DEmiRs) were screened. Integrated analysis of RNA-seq and sRNA-seq data revealed that miR172-AP2 and miR156-SPL modules were crucial in regulating bicolour pattern formation. When PhAP2 was transiently silenced in cineraria capitulum by virus-induced gene silencing (VIGS), the colourless region of ray florets increased and the coloured region changed from carmine to pink. Meanwhile, PhCHS2, PhDFR3 and PhANS were down-regulated, while PhLAR was up-regulated significantly. It was hypothesized that PhAP2 functions as an inhibitor of bicolour pattern appearance and could influence flavonoid biosynthesis. Overall, our study revealed a possible regulatory network of miRNA-mediated bicolour pattern appearance in P. hybrida, which could enrich the post-transcriptional regulatory mechanisms of flower spots formation in ornamental plants.

Entrepreneurial psychosocial profile of university women in the State of Mexico, Mexico

The present empirical research is a descriptive and correlational study from the psychosocial perspective, the objective is to analyze the relationship between the intention to undertake and variables such as family with businesses, work intention, initial motivations, personality traits, individualistic, collectivist and mixed values, support for self-employment in the educational center, difficulty to create a company and pereception of the entrepreneur, to integrate an entrepreneurial psychosocial profile of university women from Higher Education Schools in the State of Mexico, Mexico. The sample under study was obtained with the participation of 297 women. Among the main findings is the existence of weak positive relationships in most of the variables studied about entrepreneurship. The risk-taking personality trait is less commonly observed. The most important human values observed are individualistic self-direction, collectivist benevolence, and universalism as mixed value, in this sense, entrepreneurship in commercial businesses and social entrepreneurship are alternatives for the intention of entrepreneurship in university women. Regarding the support from the Educational Center, the correlation was little or non-existent, however, recovering the importance of promoting visits to companies to receive advice or seminars, university women also state that self-employment is stimulated, but the knowledge offered has a low average trend. Another finding is perceived difficulties, which are external such as funding, grants, bureaucracy and advice. Finally, the perception of the entrepreneur is positive.

Motion-pressure coupled control and simulation of long-endurance capability for multicapsule stratospheric airships

The current study focuses on the motion-pressure coupled control for a multicapsule stratospheric airship and transforms the path-tracking and heading-hold control of airships into guidance tracking with a time-varying weighted sum of longitudinal and lateral velocities by the definition of compound speed. Herein, an improved nonlinear predictive control method is provided to reduce the control energy consumption by the rolling optimization of controller parameters based on finite time intervals, ensuring infinite-time path-tracking tasks. Simultaneously, combined with the proposed cyclic regulation process of safe pressure between internal and external capsules, this study can fully reflect the force-thermal coupled rule of airships under the actions of atmospheric environment and maneuvering force, while evaluating the long-endurance capability of airships under the conditions of safe superheating and overpressure. The effectiveness of the motion-pressure coupled controller was verified through numerical simulations, which can overcome the influence of environmental wind and achieve a tracking effect for the desired cruise path and compound speed. The airspeed provided during the cyclic circadian time caused the maximum superheating of the helium controlled within 30 °C. The helium in the internal and external capsules achieved circadian regulation. The equivalent micropore diameter of the capsule of 5 mm can achieve 55 days of long-endurance flight. The controller satisfies the requirements of cruise-flight application modes for multicapsule stratospheric airships with important engineering value.

Inventory of plants as food source for Apis sp. and Trigona sp. in Tlekung Batu East Java Indonesia

This study aims to identify plant species and analyze the density (D), frequency (F), Importance Value Index (IVI) of each plant that is a source of food for Apis sp. and Trigona sp. in Tlekung Village. This research was conducted using survey and sampling methods in 3 garden locations where there is honey bee cultivation. Each location has 10 plots, one plot has an area of 1m x 1m. Data analysis using RD, RF, and IVI formulas. The results of the study were 2579 individuals consisting of 37 species from 20 families and 18 orders. The plant species that has the largest IVI is Synedrella nodiflora (66.30) from the family Asteraceae order Asterales as well as recommendations to be provided around the garden to support the feed of Apis sp. and Trigona sp.

Sistem Informasi Manajemen dalam Data Pegawai Pendidikan

This study aims to find out how the benefits of management information systems in the knowledge of employee data. This research is library research. The results of the study conveyed that for knowledge, the data processing process functions as an executor of arithmetic, logical processes for data, storing and processing data programs, taking data input programs so that they can be used at any time, minimizing human labor, and getting more accurate results and minimal errors. The function of the database is to group data to facilitate data identification, the database prepares data in accordance with user requests for information quickly and accurately. Employee data has important value for organizations because it can be used to make informed decisions and improve operational efficiency. Good data can be organized in a database. The benefit of using a management information system is that it makes it easier for management to plan, direct, and supervise the course of business.

Obesity- and lipid-related indices as a predictor of type 2 diabetes in a national cohort study.

Type 2 diabetes mellitus (T2DM) remains a major and widespread public health concern throughout the world. The prevalence of T2DM in the elderly has risen to the top of the list of public health concerns. In this study, obesity- and lipid-related indices were used to predict T2DM in middle-aged and elderly Chinese adults. The data came from the China Health and Retirement Longitudinal Study (CHARLS), including 7902 middle-aged and elderly participants aged 45 years or above. The study assessed the association of obesity- and lipid-related indices and T2DM by measuring 13 indicators, including body mass index (BMI), waist circumference(WC), waist-height ratio (WHtR), conicity index(CI), visceral adiposity index (VAI), Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), a body shape index (ABSI), body roundness index (BRI), triglyceride glucose index (TyG-index) and its correlation index (TyG-BMI, TyG-WC, TyG-WHtR). The association of 13 obesity- and lipid-related indices with T2DM was investigated by binary logistic regression. Additionally, the predictive anthropometric index was evaluated, and the ideal cut-off value was established using the receiver operating characteristic (ROC) curve analysis and area under the curve (AUC). The study included 7902 participants, of whom 3638(46.04) and 4264(53.96) were male and female. The prevalence of T2DM in mid-aged and old adults in China was 9.02% in males and 9.15% in females. All the above 13 indicators show a modest predictive power (AUC>0.5), which was significant for predicting T2DM in adults (middle-aged and elderly people) in China (P<0.05). The results revealed that TyG-WHtR [AUC =0.600, 95%CI: 0.566-0.634] in males and in females [AUC =0.664, 95%CI: 0.636-0.691] was the best predictor of T2DM (P<0.05). Most obesity- and lipid-related indices have important value in predicting T2DM. Our results can provide measures for the early identification of T2DM in mid-aged and elderly Chinese to reduce the prevalence of T2DM and improve health.

INTERLEUKIN-11 AND CARDIOVASCULAR PATHOLOGY

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality. An important task in cardiology is the search and study of new biomarkers. Scientific interest is actively focused on the study of interleukin-11 (IL-11). The purpose of the literature review was to analyze experimental and clinical studies devoted to the study of IL-11 as a diagnostic and prognostic marker in CVD. Material and methods. The article provides an overview of current publications. An analysis of literature sources was carried out, including all relevant publications in the databases PubMed, RSCI, MedLine, Google Scholar, Science Direct. Results. In endothelial cells, IL-11 primarily promotes angiogenesis, thereby exerting a beneficial effect on coronary heart disease. IL-11 also promotes vascular remodeling by inducing smooth muscle cell transformation and fibroblast activation. IL-11 may be involved in the onset and progression of pulmonary hypertension through the JAK/STAT3 pathway and aortic dissection processes through the non-classical ERK pathway. Conclusion. The presented literature review indicates the potentially important diagnostic and prognostic value of IL-11 assessment. Regulating the concentration and expression of IL-11 may be a promising strategy for the treatment of CVD.

Classification of Standing Types at PT. Work Locations. Sustainable Forest Tusam in Krakap Dusun, Umang Village, Linge District, Central Aceh District

PT. Tusam Hutani Lestari is a company with an area of ± 97,300 Ha which has an Industrial Plantation Forest Concession Rights permit number 452/Kpts-11/92 dated 14 May in Aceh Province which is in the districts of Central Aceh, North Aceh, Bener Meriah and Bireuen. With a large working area, the forest area is divided into 6 working blocks, namely the Mount Salak block, Blangkuyu block, Lampahan block, Burni Telong block, Bidin block and Jambu Aye block, making this area have varied biodiversity. This observation aims to determine the diversity of types of stand distribution found on mixed forest land and to determine the value of the important value index (INP) for a type of stand at the PT work site. Tusam Sustainable Forest. The results show that there are 8 types of stands or trees with a total of 17 individuals in the mixed forest area. The dominant important value index (INP) is found in Eucalyptus trees at 60.57% and Pine at 58.66%, while the INP for all plant types in mixed forest area cover is 300% and is included in the high value, and the diversity index for the growth rate of mixed forest land cover shows that the PT Tusam Hutani Lestari work area is included in the medium criteria.