Here, we used mathematical modeling to predict and simulate the behavior and effect of temperature on human skin, together with studying the effects of the blood perfusion parameters, the time of tissue exposure to the laser, and the effect of the delay times on temperature distribution on living tissue. The model that has been used is a dual-phase lag DPL bioheat transfer model. The solution of the model has been obtained by using the analytical scheme represented by Laplace transforms, as well as the numerical scheme represented by the implicit finite difference method. The paper involves comparing analytical and numerical solutions, a comparison between the temperature distribution according to various bio-heat models and the resulting thermal damage. The results of the DPL bioheat model have been compared with the previous study and it showed. A favorable convergence results have been presented graphically and discussed in detail.