Globally, the performance of the construction industry is often cited as one of low performance. Whilst concerted efforts have been made aimed at improving the performance of the construction industry through various strategies, the impact of construction site managers’ technical and managerial skills remains relatively unexplored. This study assesses the impact of construction site manager’s technical and managerial skills on quality performance of construction projects in Ghana. The descriptive survey design was used for the study. Purposive sampling technique was used to select 115 respondents for the study. The findings of the study revealed that construction site managers were not especially skilled in technical, legal, interpersonal, managerial, and business skills. The findings of the study suggest that the level of implementation of quality management practices among construction site managers for attaining high quality standards was acceptably high. The study revealed that the most significant skill requirements that can improve quality performance at construction sites was managerial and technical skills. The findings of the study disclosed that there is a statistically significant positive correlation between construction site manager’s skills and quality performance of construction projects they managed. It is recommended among others that efforts should be made by the top management of construction firms to create a quality management culture throughout the entire organisations. . Keywords: Construction Site Manager, Managerial Skills, Technical Skills, Quality Performance.