Implant Success Rate Research Articles

New Artisse intrasaccular device for intracranial aneurysm treatment: short term clinical and angiographic result from the prospective registry INSPIRE-A

BackgroundIntrasaccular devices have broadened treatment options for wide necked aneurysms. This study presents the preliminary experience with the Artisse 2.0 device.MethodsInnovative NeurovaScular Product SurveIllance REgistry (INSPIRE) is a non-randomized, multicenter,...

Identification of Alterations in the Expression of Genes Related to the Implant Failure in Spanish Patients with Down Syndrome and Periodontal Disease

Background: Individuals with Down syndrome exhibit a higher prevalence of periodontal disease, which can lead to implant loss. This study aims to identify genetic markers associated with implant loss in these patients, providing insight into potential predictive and therapeutic approaches. Methods: A systematic analysis was conducted, including both clinical and genetic data from Down syndrome patients with a history of dental implants. Genetic profiling was performed using Transcriptome Analysis Console (TAC version 4.0 Applied BiosystemsTM, Thermo Fisher Scientific, Waltham, MA, USA), focusing on genes previously implicated in periodontal disease and bone metabolism. Statistical analysis identified correlations between genetic variants and implant survival rates. Results: The analysis revealed statistically significant alterations in several genes related to inflammation and bone remodeling. Key findings included alterations in the expression of the genes MMP15, MMP17, S100B, GHR, DNAH6, and ZCCHC14 in patients with implant failure. These genetic markers were strongly correlated with compromised osseointegration and implant loss. These findings underline the role of genetic predisposition in the failure of dental implants among individuals with Down syndrome. Conclusions: Genetic markers, particularly those involved in inflammation and bone metabolism, play a critical role in implant loss among Down syndrome patients with periodontal disease. Recognizing these markers can aid in early diagnosis and personalized treatment strategies, potentially improving implant success rates.

Clinical and Radiographic Outcomes of Single-Unit Implant- Supported Restorations: A 12-Month Cross-Sectional Clinical Study.

This retrospective clinical study aims to analyze single-unit implant-supported restorations' clinical and radiographic outcomes comprehensively. In this retrospective study, patients who had undergone 12 months of implant-supported singleunit fixed prosthetic treatment were scanned from the archives, and a hundred patients were included in the study. Implant success and survival rates were assessed according to the consensus decisions published at the International Oral Implantology Congress in 2007. Prosthetic complications such as chipping, screw loosening, and decementation were also evaluated. In addition, success/survival rates and prosthetic compositions were associated with some surgical and prosthetic parameters. According to the success/survival criteria, 88% of the implants were successful, 10% had satisfactory survival, and 2% had compromised survival. The risk of satisfactory or compromised survival was 62.5 times higher in individuals with inadequately keratinized mucosa compared to those with adequately keratinized mucosa (p < 0.001). It was also 5.736 times greater for extractions due to periodontal disease versus endodontic reasons (p = 0.010) and 4.629 times higher for implants with diameters less than 3.75 mm compared to those between 3.75 mm and 5 mm (p = 0.037). Screw loosening was observed in 15% of the evaluated restorations, decementation in 13% and chipping in 4%, and the risk of screw loosening was 4.444 times higher for screw retention abutments compared to standard abutments (p=0.015). Insufficient keratinized mucosa, periodontal problems leading to tooth extractions, and the use of narrowdiameter implants can negatively affect the success of implant procedures. Loosening in screw-retained restorations is due solely to screw loosening, which is a high risk for screwretained restorations. Loosening in cement-retained restorations, on the other hand, is caused by the decementation of the prosthetic restoration or loosening of the abutment screw supporting the restoration.

The Expression Pattern and Functional Analysis of Extracellular Vesicle Long Non-Coding RNAs from Uterine Fluid During Implantation in Pig.

Long non-coding RNAs (lncRNAs) act as competing endogenous RNAs and play significant roles in porcine embryo development. Extracellular vesicles (EVs) in the uterine fluid (UF) can target and deliver maternal endometrial signalling molecules to embryonic trophoblast cells, exerting crucial regulatory effects during embryo implantation. However, the specific roles of lncRNAs carried by UF-EVs during the embryo implantation period have not been thoroughly reported in the literature. In the present study, high-throughput sequencing and biological tools were applied to analyse lncRNAs in UF-EVs on days 9, 12, and 15 of pregnancy to identify key regulatory lncRNAs in UF-EVs during the porcine embryonic implantation period and to explore their expression patterns and functional roles. A total of 30,203 lncRNAs were identified and 7879 differentially expressed lncRNAs were screened, and qRT-PCR was used to verify the sequencing data. Days 9-12 of pregnancy represent a critical stage of embryo implantation characterised by substantial morphological changes in porcine embryos. During this period, we identified a total of 4348 differentially expressed lncRNAs. Through screening and validation, we discovered that LNC_026212 was highly expressed on day 12 of pregnancy and can promote the proliferation and migration of porcine trophoblast cells (PTr cells). These novel findings contribute to our understanding of the impact of lncRNAs on porcine reproductive processes, offering new research directions to improve the success rate of embryo implantation in pigs.

EVALUATION OF THE EFFECTIVENESS OF IMMEDIATE DENTAL IMPLANTS PLACED IN EXTRAXTION SOCKETS WITH PERIAPICAL PATHOLOGY. A CONTROLLED CASE SERIES

Background:Immediate placement of implants in post-extraction sockets is a common and well-established treatment modality. However, extraction sockets with periapical pathology may negatively impact the outcome of this treatment procedure. Objective: The aim of this study was to evaluate the clinical outcomes of immediate placement of dental implants in infected extraction sockets with periapical pathology. Materials and Methods: The study included 37 patients who underwent tooth extraction with periapical pathology and immediate 151 Bio3 GmbH (Germany) implants placement. Postoperative results; implant survival, implant failure, marginal bone loss (MBL), and patient-reported function of the implants were assessed clinically and radiographically. Results: There were no complications during implant placement and in the postoperative period, no signs of infection around the implants were detected at the follow-up visit 4 weeks after implant placement, the soft tissues were in good condition, as evidenced by their healthy color and texture. The mean RFA for151 implants was 63.7 ISQ (implant stability), and after 3-5 months, respectively, 72.4 ISQ. The mean MBL after 12 months was 0.94, after 36 months the mean MBL was 1.28, at 60 months follow-up the mean MBL was 1.42. The functional and aesthetic results of prosthetic restoration were satisfied by the patients, as chewing function was restored, the esthetics of the facial profile and occlusion improved. The success rate of immediate implants after 5 years was 96.8%, and shows a similar survival rate to the published success rates for immediate implants placed in non-infected sites. Conclusion: Evidence suggests that immediate placement of implants in areas with periapical infections is a predictable and effective treatment protocol if the areas are thoroughly debrided prior to implant placement, high implants stability is achieved during implant placement, and systemic antibiotics are used.

Advancements in Hyaluronic Acid Effect in Alveolar Ridge Preservation: A Narrative Review.

Background/Objectives: Tooth extraction induces significant alveolar ridge dimensional changes and soft tissue modifications, often leading to challenges in implant placement or conventional prosthetic rehabilitation. Alveolar Ridge Preservation (ARP) strategies aim to mitigate post-extraction resorption of the alveolar ridge, enhancing both the quality and quantity of bone and soft tissue during healing. Hyaluronic acid (HYA) has emerged as a promising biological agent for ARP due to its osteoinductive, antimicrobial, and anti-inflammatory properties. However, the effects of HYA in ARP remain inconsistently reported. This study aims to assess current clinical and preclinical evidence regarding the biological effects of HYA and its application in ARP. Additionally, it evaluates HYA's impact-alone or in combination with other products-on hard and soft tissue dimensional changes, early wound healing, and implant success rates. Methods: A comprehensive electronic literature search was conducted, and studies meeting the inclusion criteria were critically evaluated. Relevant data were extracted from the final selection of articles. Results: Thirteen publications were evaluated. Some studies reported a significantly improved newly formed bone following ARP with intra-socket HYA application as a single approach (p = 0.004). Combining HYA with a bone graft and a free palatal graft resulted in significantly greater amounts of newly formed and mature bone, reduced clinical bone width changes, lower radiographic crestal bone loss (p < 0.01), and diminished radiological volumetric and linear bone resorption (p = 0.018). Short-term follow-up data indicated improved soft tissue healing associated with HYA-based ARP. While HYA appears to have a protective effect on ridge dimensional changes in ARP, other studies reported no significant differences in radiographic bone dimensional changes or soft tissue improvement. Conclusions: The addition of HYA to bone grafts may enhance some ARP outcomes. However, the variability in outcomes and methodologies across the evaluated studies precludes drawing definitive clinical conclusions. Further robust research is needed to clarify HYA's role in ARP. With respect to clinical significance enhancing the understanding of ARP management strategies and their effects on post-extraction sockets empowers clinicians to make more informed decisions. The knowledge of HYA effects facilitates the selection of personalized ARP approaches tailored to optimize outcomes for subsequent interventions.

Left Bundle Branch Area Pacing Versus Right Ventricular Pacing in Patients With Atrioventricular Block: A Systematic Review and Meta-Analysis.

Left bundle branch area pacing (LBBAP) is a new technique for patients with atrioventricular block (AVB) and preserved left ventricular ejection fraction (LVEF), potentially offering better cardiac function than right ventricular pacing (RVP). We searched databases and registries for studies that compared LBBAP with RVP in patients with AVB and preserved LVEF. We extracted data on various outcomes and pooled the effect estimates using random-effects models. Our meta-analysis included 14 studies (10 observational and 4 RCTs) involving 3062 patients with AVB. The analysis revealed that the QRS duration was significantly shorter in the LBBAP group compared to the RVP group [MD = -35.56 ms; 95% CI: (-39.27, -31.85), p < 0.00001]. Patients in the LBBAP group also exhibited a significant increase in left ventricular ejection fraction (LVEF) [MD = 5.48%; 95% CI: (4.07%, 6.89%), p < 0.00001], and a significant reduction in left ventricular end-diastolic diameter (LVEDD) compared to RVP [MD = -3.98 mm; 95% CI: (-5.88, -2.09 mm), p < 0.0001]. In terms of clinical outcomes, LBBAP was associated with a significantly lower risk of heart failure hospitalizations (HFHs) compared to RVP [OR = 0.26; 95% CI: (0.16, 0.44), p < 0.0001]. However, no significant differences were observed between the two groups in the implant success rate, pacing impedance, or pacing threshold. The RVP group demonstrated a significantly higher R-wave amplitude increase than the LBBAP group [MD = 0.85 mV; 95% CI: (0.23, 1.46), p = .007]. Lastly, there was no significant difference in the incidence of complications between the two groups [OR = 2.12; 95% CI: (0.29, 15.52), p = 0.46]. LBBAP outperforms RVP in several cardiac function indicators, suggesting it may be a superior pacing method for AVB patients with preserved LVEF. However, the small sample size in studies and the result in heterogeneity call for more research to validate these findings and assess LBBAP's long-term effects.

Immediate Full-Arch Restorations Supported by Conventional Implants Plus Uni- or Bilateral Zygomatic Implants: A Three to Five Years Retrospective Radiologic and Clinical Comparison.

The study aimed to compare the short-term outcomes (3.7±0.4yrs) of full-arch immediately loaded fixed maxillary prostheses supported by conventional and unilateral single zygomatic implants versus those supported by conventional and bilateral single zygomatic implants. A retrospective analysis was conducted on patients suffering severe bone loss in the posterior area of the maxilla. The success of zygomatic implants was defined following Offset-Rhinosinusitis-Infection-Stability (ORIS) criteria. The criteria used to define success of standard dental implants were absence of mobility, pain, discomfort/neurologic disorder, and of persistent or chronic infection. The level of significance was 0.01. Thirty-eight patients received 2-5 standard implants plus two zygomatic implants (bilateral), whereas 10 patients had 3-5 standard implants plus a single zygomatic implant (unilateral). The cumulative success rate for standard implants was 99% and 97.3%, respectively, in the bilateral and unilateral groups. Four patients showed symptoms of acute rhinosinusitis (R-criterion): 1 in the unilateral and 3 in the bilateral group. Following the O-criterion, just 2 dental implants in the bilateral group showed a success grade 1. One zygomatic implant, belonging to the group bilateral, developed peri-implant mucositis with a success grade 3 (I-criterion). All zygomatic implants were checked individually and did not show either any signs of mobility or rotation after applying forces to the implant (S-criterion). The ORIS criteria divided the implants into three groups according to the success grades I,II,III: 32,36,8 for the bilateral, and 6,1,3 for the unilateral group, with no significant difference between the two groups. No zygomatic implant failure occurred so that the same zygomatic implant success rate (100%) was recorded for both groups. A prosthetic failure was registered in the unilateral group. The overall prosthesis success rates were 89.5% and 70%, respectively, in the bilateral and unilateral groups. A high degree of success was achieved for both groups treated with zygomatic implants, although in group unilateral there was one failure of a standard dental implant placed in the posterior area. This suggested that the use of zygomatic implants could provide adequate support to the fixed full-arch prostheses even in the configuration with a single unilateral zygomatic implant.

Surface steel ball calibration - A novel method for facilitating fluoroscopic measurement during implantation of WATCHMAN.

Although the method of autocalibration or calibration based on catheter diameters was proposed for fluoroscopic measurement during percutaneous left atrial appendage occlusion (LAAO), it may be imprecise and lead to mismeasurement. We sought to investigate whether the utilization of the surface steel ball calibration (SSBC) method under fluoroscopy could facilitate the fluoroscopic measurement of the post-implanted WATCHMAN device (Boston Scientific Corporation, Natick, MA, USA) in LAAO. This retrospective study included 97 consecutive patients who underwent percutaneous LAAO with the WATCHMAN device. The SSBC method and sheath calibration method under fluoroscopy, and transesophageal echocardiography (TEE) were employed to measure the diameter of the post-implanted device during the LAAO procedure. The results of the three methods were then compared. The success rate for procedural WATCHMAN implantation was 100 %. The mean maximal diameter of the post-implanted devices was 24.7 ± 3.1 mm, 23.5 ± 3.2 mm, and 24.2 ± 3.0 mm, as measured by the SSBC method, sheath calibration method, and TEE, respectively (all p < 0.001). The relevant coefficient of correlation between the SSBC method/TEE, SSBC method/sheath calibration method, and TEE/sheath calibration method, was 0.94, 0.93, and 0.89, respectively (all p < 0.001). The SSBC method, when employed under fluoroscopy, demonstrated a high correlation with the sheath calibration method and TEE for measurements. It may be applied to facilitate fluoroscopic measurements during percutaneous LAAO procedures.

Effect of Treatment with Progestins and Antiplatelet Agents on IVF in Women with Adenomyosis and Recurrent Implantation Failure.

Background: This prospective study aims to identify the effect of the dienogest 2 mg/day and aspirin 150 mg/day combined treatment for two months before frozen ET on the assisted reproduction outcome in women with adenomyosis and recurrent implantation failure (RIF). Methods: Patients were selected based on specific criteria and divided into two groups (with and without treatment). Preimplantation biochemical parameters and ultrasonographic features (endometrial thickness, uterine peristalsis, and junctional zone thickness) were compared with pregnancy rate in a non-natural cycle frozen embryo transfer technique. A comparison between the two study groups indicated an increased successful implantation rate and clinical pregnancy rate (25% vs. 7.4%). Results: These results were attributed to the reduced uterine peristalsis and the reduction in thickness of the junctional zone following treatment. Available data were limited due to the nature of the study though maximal effort was exerted for the selected patients between groups to be as demographically similar and free from other potential pathology that may affect the results. Conclusions: In conclusion, it appears that the above stated treatment improves outcomes in women with adenomyosis and RIF; the parameters used may provide an insight as to the reasons why this occurs, though an explanation of the molecular mechanisms is still elusive.

Success Rates of Dental Implants in Patients With Diabetes: A Systematic Review.

This systematic review evaluates the success rates of dental implants in patients with type 2 diabetes mellitus, focusing on outcomes such as implant survival, marginal bone loss, and peri-implant biomarkers. A comprehensive literature search was conducted across multiple databases, including PubMed, Cochrane, Embase, Scopus, and Web of Science, to identify relevant systematic reviews and meta-analyses. Four studies were included, encompassing diverse populations and interventions. Findings indicate that diabetes, when well-managed (HbA1c < 8%), does not significantly compromise implant survival rates, with survival percentages ranging from 96.1% to 97.3% at one year and 87.3% to 96.1% at five years, comparable to non-diabetic populations. However, peri-implant health metrics, such as marginal bone loss (mean difference: -0.08 mm; 95% CI: -0.25 to 0.08) and probing depth, were adversely affected in poorly controlled diabetes (HbA1c > 8%), highlighting the critical role of glycemic control. Advanced statistical approaches, including dose-response relationships, revealed a progressive worsening of peri-implant outcomes as HbA1c levels increased. The review underscores the importance of interdisciplinary care and strict adherence to clinical protocols to optimize outcomes for diabetic patients receiving dental implants. Despite robust findings, limitations include heterogeneity among included studies and the need for long-term data to validate the observed trends. Future research should focus on standardized reporting and exploring the impact of advanced glycemic thresholds on implant success.

MINI DENTAL IMPLANTS: ADVANTAGES, LIMITATIONS AND CLINICAL APPLICABILITY

Mini dental implants offer an effective and minimally invasive alternative for edentulous patients, especially those with advanced bone resorption, who are not ideal candidates for conventional implants. This review analyzes the advantages and limitations of mini-implants, emphasizing their clinical applicability in the stabilization of mobile prostheses and temporary fixed restorations. While mini-implants have many benefits, such as reduced costs, simplified procedure, and shorter recovery time, they also have important limitations, including their reduced ability to sustain high occlusal forces and inferior long-term durability. Advanced biomaterials, such as titanium alloys, are essential for the success of mini-implants, ensuring osseointegration and reducing the risk of inflammation. In addition, essential oils, with antimicrobial and anti-inflammatory properties, help maintain peri-implant health, preventing infections and peri-implant complications. The integrative approach, which combines the use of biomaterials and essential oils, can significantly improve the stability and success rate of dental mini implants, providing patients with a durable and functional solution for dental restoration. This analysis emphasizes the importance of the appropriate selection of treatment for each patient according to clinical needs and aesthetic requirements.

The Success Rate of Dental Implants in Type 2 Diabetic Patients. A Systematic Review

Purpose: Diabetes has always been a challenge in implant treatment. The hyperglycemia present in diabetic individuals negatively affects bone healing, and with an increased risk of osteoporosis and delayed wound healing, it impacts the success rate of implants. However, implants in diabetic patients with controlled diabetes have a high success rate similar to that of non-diabetic individuals. This study aims to determine the success rate of dental implants in patients with type 2 diabetes. Materials and Methods: Based on PRISMA guidelines, this systematic review included 23 articles, comprising ten articles from the PubMed database and 13 articles from the Google Scholar database. The search strategy included terms related to dental implants in diabetic patients, and the performance of articles was examined systematically. Results: Overall, the success rate of dental implants in individuals with type 2 diabetes in the articles included in this study was 93.67%, and the failure rate was 6.33%. Specifically, the average HbA1c was 7.26%, the average age was 52.41 years, the average number of implants was 1.91, and the duration of diabetes in individuals included in this study was 7.46 years. Therefore, factors such as HbA1c, age, number of implants, duration of diabetes, and blood sugar control (whether controlled or uncontrolled) are reasons for the similarities and differences in the success rate of implants in patients with type 2 diabetes. An increase in these factors leads to a higher rate of dental implant failure in these individuals (due to delayed wound healing, weakened immune system, and increased susceptibility to osteoporosis and infections). While the first three factors were reasons for the differences in implant success rates between diabetic and non-diabetic groups, the success rate for non-diabetic individuals included in this study was 98.68%, and the failure rate was 1.32%. The average HbA1c was about 5.39%, the average age was 49.98 years, and the average number of implants was 1.63. Conclusion: In conclusion, this systematic review aimed to determine the success rate of dental implants in patients with type 2 diabetes. Our findings indicate that dental implants in patients with controlled type 2 diabetes have a high success rate similar to non-diabetic patients. However, in patients with poorly controlled diabetes, the success rate decreases significantly. Therefore, the controlled blood sugar, HbA1c level, age, number of implants and the duration of diabetes are crucial factors in achieving a high success rate in diabetic patients.

Cephalopod Waste Derived Chitosan: A Promising Biomaterial for Revolutionizing Dental Applications - A Mini Review

This study adopts a comprehensive approach to gathering relevant information. A thorough literature search included research articles, clinical studies, and reviews of the application of chitosan in dentistry. The selected sources were critically analyzed to identify key trends, outcomes, and advancements in the field. Chitosan, derived from chitin, has remarkable versatility in dental applications. It holds promise in multiple areas, including endodontic therapy, periodontal treatment, implant dentistry, oral surgery, and as an ingredient in restorative dental materials. Of note is the potential for dental pulp regeneration, which offers a promising avenue for tissue engineering in dentistry. This review revealed that the multifaceted properties of chitosan contribute to its ability to address a wide array of dental challenges, from root canal treatment to combating periodontal diseases and enhancing implant success rates. This review highlights the significant impact of chitosan on the reshaping of modern dental practices. Furthermore, by highlighting its versatile applications and potential benefits, this study contributes to our understanding of the transformative role of chitosan in dentistry. These findings emphasize the need for further research and exploration to unlock the full potential of chitosan, ultimately paving the way for innovative solutions to longstanding dental issues. As the capabilities of chitosan continue to evolve, it holds the potential to redefine dental care standards and establish itself as a cornerstone for future dental therapies.

Evaluating the Success Rate of Dental Implants in Diabetic Patients: A Systematic Review of Clinical Outcomes and Risk Factors

Diabetes mellitus is a chronic condition that poses significant challenges for dental health, particularly in the context of dental implants, where effective osseointegration and healing are crucial for success. Diabetic patients may experience delayed wound healing and increased susceptibility to infections, potentially impacting the success rate of dental implants. This systematic review aims to evaluate the success rates of dental implants in diabetic patients compared to non-diabetic individuals and to identify key clinical outcomes and risk factors influencing implant success. A comprehensive literature search will be conducted across major databases, including PubMed, Cochrane Library, and Embase, for studies published from 2016 onwards. Studies assessing implant success rates, complications, and relevant factors such as glycemic control and diabetes type will be included. Data will be extracted systematically, and quality assessment tools will be applied to evaluate the risk of bias. Findings from this review are expected to clarify the impact of diabetes on implant outcomes, provide evidence-based recommendations for managing diabetic patients undergoing implant procedures, and highlight areas for further research.

Anti-diabetic therapies on dental implant success in diabetes mellitus: a comprehensive review.

Dental implant therapy faces challenges in patients with Type 1 and Type 2 Diabetes Mellitus (T1DM and T2DM) due to adverse effects on bone metabolism and immune response. Despite advancements, diabetic patients face higher risks of peri-implantitis and compromised osseointegration. This review assesses the impact of anti-diabetic medications on implant outcomes, offering insights to bridge the gap between animal studies and clinical practice. By evaluating pharmacotherapeutic strategies in preclinical models, this review guides future research designs to improve implant success rates in diabetic individuals. A comprehensive literature review identified 21 animal studies examining the impact of anti-diabetic medications on dental and bone implants. These studies explored diabetes models, medication regimens, and designs to assess outcomes related to bone metabolism, osseointegration, and peri-implant tissue responses. The findings are systematically summarized, highlighting the scope, design, and procedures of each study. An example includes placing a dental implant in the molar region of a mouse, providing insight into preclinical approaches. Twenty-one animal studies, primarily using rodents, investigate various anti-diabetic medications on dental and bone implants. Interventions include insulin, aminoguanidine, voglibose, sitagliptin, exenatide, and metformin, analyzing outcomes like bone-implant contact (BIC), bone volume (BV), and counter-torque values in T1DM and T2DM models. The impacts of these medications on implant osseointegration under diabetic conditions are detailed, with their benefits and shortcomings assessed. The findings and challenges of existing animal studies on diabetes mellitus (DM) and implant osseointegration are presented. Despite T2DM prevalence, research primarily focuses on T1DM models due to easier experimental practicalities, limiting applicability. Inconsistent protocols in studies compromise reliability regarding anti-diabetic treatments' effectiveness on osseointegration. Standardized methodologies and long-term assessments of local drug delivery alongside systemic anti-DM treatments are crucial to manage DM-related complications in implant dentistry. Insulin administration in short-term T1DM animal studies enhances implant osseointegration. However, the efficacy of non-insulin medications remains inconclusive. Rigorous experimental designs are needed to address inconsistencies and assess long-term impacts. Larger-sized (e.g., porcine) animal studies across various intraoral implant scenarios are required. Future research should focus on enhancing clinical applicability and improving implant stability in evolving conditions.

Minimal invasive sinus elevation (MISE), a different approach for maxillary sinus lift surgery

Aim: The maxillary sinus lift is a crucial surgical procedure performed to increase the vertical height of the remaining bone, often required before implant placement. Several techniques are used to approach the maxillary sinus, with varying results. Among them, it is possible to mention the minimal invasive sinus elevation (MISE) technique. Methods: This paper provides a comprehensive review of the MISE technique, its materials, and surgical methods. It analyzes the outcomes compared to conventional methods and discusses its applicability in different clinical scenarios. Results: The MISE technique has proven effective in increasing bone height with a lower risk of membrane perforation compared to traditional methods. It offers high implant success rates and minimal post-operative complications, with strong patient outcomes regarding bone regeneration and implant stability. This section will analyze these results with both quantitative and qualitative evaluations. Conclusions: The MISE technique notably improves sinus lift procedures, providing a minimally invasive method with reliable clinical results. Its predictability and lower risk of membrane perforation make it well-suited for implant surgeries involving sinus elevation. Future studies should explore long-term results and refine the technique for broader clinical use.

Evaluation of pediatric cochlear implantation results.

Cochlear implantation is an effective method of auditory rehabilitation. Nevertheless, the results show individual variations depending on several factors. To evaluate cochlear implantation results based on the APCEI profile (Acceptance, Perception, Comprehension, Oral Expression and Intelligibility) and audiometric results. This was a cross-sectional study including children under 18 years of age who had a unilateral cochlear implant and whose implants had been activated at least 1 year prior to the start of the study. During this study period, 75 children underwent unilateral cochlear implantation. Among them, 44 patients had reached one year after the activation of the implant at the time of the evaluation and were then included in the analytical part. A speech-language pathology assessment using the APCEI scale was conducted for 44 cases. Thirty-eight cases had an audiometric assessment (free-field tone audiometry and speech audiometry). We assessed the results of the APCEI profile based on various factors. The mean cochlear implantation age was 5 years and 2 months. The electrode insertion was complete in all cases. The APCEI profile average was 3.6. Four children had poor results, 27 children had good results, and 13 children had excellent results. The average hearing threshold in tonal audiometry was 39dB. In voice audiometry, the average intelligibility threshold was 65% with the cochlear implant versus 75% with the cochlear implant and the contra lateral hearing aid. According to the statistical study, only two factors were considered to have a positive influence on the success rate of cochlear implantation: the regular use of preoperative amplificative prostheses and the follow-up of speech therapy sessions in pre-operative. The effectiveness of cochlear implantation depends on several factors. Multidisciplinary management improves the results.

Bone regeneration and dental implant surgeries in florid cemento-osseous dysplasia: A case report.

Cemento-osseous dysplasia (COD) is a benign fibro-osseous pathology in which fibrous connective tissues, osteoid and cementum-like materials, replace bone. Concerning the hypovascularization and increased mineralization of bone that occurs in these patients, the clinician may face two types of problems: infectious complications such as osteomyelitis and increased implant failure. The present study aims to report the successful and innovative management of a COD patient complicated by mandibular osteomyelitis and the implant rehabilitation of this area. We report the management of a 54-year-old patient presenting with florid cemento-osseous dysplasia (FCOD) complicated by mandibular osteomyelitis, which required antibiotic administration and two surgeries to resolve. This area was then reconstructed with guided bone regeneration before three implants were placed using guided surgery, including one implant in a dysplastic area and one in the graft site. Osseointegration of the implants allowed rehabilitation with a supra-implant bridge. An optimal functional rehabilitation and complete integration of implants were observed 13 months after the surgery. Eight cases of implant placement in COD patients have been reported before in the literature (n=35 implants). The success rate of dental implants in non-dysplastic areas is comparable to the general population, but it decreases when implants are placed in dysplastic areas. Guided implant surgery is an interesting tool for placing implants outside dysplastic regions.

Long-Term Success of Dental Implants in Atrophic Maxillae: A 3-Year Case Series Using Hydroxyapatite and L-PRF.

Dental implants are essential for the prosthetic rehabilitation of edentulous patients, requiring adequate bone volume and density for osseointegration and load support. The posterior region of the maxilla, commonly deficient in bone quality and quantity, represents a clinical challenge. This case series reports an analysis involving 69 dental implants in the atrophic maxilla of nine patients. The procedures adopted combined alloplastic hydroxyapatite grafting and leukocyte platelet-rich fibrin (L-PRF) applied to the alveolar ridge and maxillary sinus lift. With an average follow up of three years after the installation of the prostheses, an implant success rate of 98.5% was observed, showing integration and functional stability. The strategy of combining hydroxyapatite with L-PRF proved to be effective in increasing bone volume and promoting osseointegration. These findings indicate that the technique and biomaterials are viable for rehabilitating atrophic maxillae in the posterior region, offering long-lasting clinical results and a high success rate.