For an imperfect production system, to reduce quality-related costs, a manager may consider investing capital in quality improvement. In general, the investment expense in reducing the defective rate of items is often paid by the vendor. On the other hand, the buyer may inspect the product quality as the order is received which implies it incurs an inspection cost. In a supply chain integrated system, to accomplish global optimisation, the vendor and buyer can agree to jointly invest capital to improve the imperfect production processes, and the buyer can remove the inspection programme as the defective rate reaches a certain low-level. Hence, this paper investigates the impacts of collaborative investment and inspection policies on an integrated inventory model with defective items. The objective of this study is to seek the optimal order quantity, shipping times from the vendor to the buyer per production run, and the defective rate that minimise the joint total cost per unit time. An algorithm is developed to find the optimal solution. Several numerical examples are presented to demonstrate the proposed model and solution procedure, and then several management insights are obtained from the numerical examples.