Taking the compressor impeller as the research object and the lightweight design as the research goal, a lattice filled lattice cell suitable for the application of rotating periodic symmetric structure is designed. Its purpose is to make the rigidity and strength of impeller adjustable and reduce the mass of impeller on the premise of meeting the design requirements. The analysis and comparison of unfilled impeller, solid impeller and lattice filled impeller with different diameters were carried out under the limit condition of 80,000 r/min. The results showed that the average circumferential deformation of lattice impeller tip with beam diameter of 0.2 mm, 0.4 mm and 1 mm was 4.84%, 3.49% and 3.71% lower than that of solid impeller. For the impeller with a lattice beam diameter of 0.4 mm, its weight can be reduced by 22.68% compared with the solid impeller. The average circumferential deformation of the tip of the lattice impeller lies between the unfilled impeller and the solid impeller. The results show that the impeller with lattice filling hub can not only reduce the weight effectively, but also improve the efficiency of the compressor.