Masonry buildings are vulnerable to extreme hydrodynamic events such as floods or tsunamis. Post-disaster surveys have shown that waterborne debris impacts can significantly damage masonry walls during these events. To simulate these actions, the current design or research practice is to compute the force–time diagram of the impact and then use it for dynamic analyses. Standing on the current knowledge, debris impacts are highly impulsive, but it is not clear if such loads are fast enough to activate the high strain rate effects in masonry, i.e. the strain rate dependency of material properties. The present study aims to answer this question, for the first time, following nonlinear Finite Element (FE) simulations. Simulations are conducted on a masonry wall, following a micro-modelling strategy, subjected to water flow and waterborne debris impact under different scenarios. It is found that the strain rates exceed the critical threshold after which strain rate effects are considerable. Such a finding, initially obtained using the minimum design demand for log-type debris imposed by ASCE/SEI 7-22, is further extended to a range of impact force–time diagrams different in impact duration and peak force (corresponding to different debris properties or flow velocity). It is also shown that the impact location (i.e. midspan or close to the boundary) affects the strain rate magnitude because of the changes in the impact stiffness and the activated failure mechanisms. Furthermore, it is found that the dynamic tensile post-elastic behaviour of the materials is the most influencing parameter in the structural response. These results open a new area in the field of assessment and design of masonry structures to waterborne debris and guide the development of future experiments, numerical simulations or design relations.