The intelligent adjustment method of the shearer drum is the key technology to improve the intelligent level and safety degree of fully mechanized mining face. This paper proposes a shearer drum intelligent height adjustment model based on rough set significance attribute reduction (AR) and fuzzy rough radial basis function neural network (FRRBFNN) optimized by adaptive immune genetic algorithm (AIGA). The model first selects the parameters of shearer process monitoring based on the importance attribute reduction algorithm of rough set, and establishes the attribute reduction set of shearer operation characteristic parameters and the drum height decision rule base. Next, a fuzzy rough radial basis function neural network determined by the decision rule space is proposed. By introducing the fuzzy rough membership function as the connection weight, the network can accurately describe the complex nonlinear relationship between the working characteristic parameters of the attribute shearer and the drum height, and measure the uncertainty of the coal seam distribution. Finally, to further optimize the performance of FRRBFNN, the adaptive immune genetic algorithm is introduced to optimize its parameters, to build a high-precision shearer drum height prediction system. For the evaluation method of the model, we use three indicators: mean absolute error, mean absolute percentage error, and root mean square error. Based on the measured data in Yujialiang area, Shaanxi Province, the experimental results show that—compared with the FRRBFNN and support vector regression (SVR) models, a gated current neural network (GRU), a radial basis function neural network (RBF), the memory strengthen long short-term memory (MSLSTM) model, and the adaptive fuzzy reasoning Petri net (AFRPN)—the MAE of the AR-AIGA-FRBFNN model for predicting the height of the left and right rollers are 18.3 mm and 17.2 mm, respectively; the MAPE is 0.96% and 0.93%, respectively; and the RMSE is 21.2 mm and 22.4 mm, respectively. The AR-AIGA-FRBFNN model is therefore more effective than the other considered methods.