ABSTRACT How do sub-state regions respond to immigration and what drives their policy choices? Combining the cross-national literature on citizenship and integration policy with the literature on immigration federalism, it is hypothesized that sub-state nationalism and multilevel party politics explain why some regions formulate more restrictive immigrant integration policies than others. Analyzing integration laws of German, Italian and Spanish regions demonstrates that socioeconomically inclusive measures dominate, regardless of national context. Where restrictive provisions occur at all, they are associated with minority nationalism and the strength of anti-immigrant parties, while leftist regions facing right-wing national governments tend to adopt a more inclusive policies.