In this study, the effect of 1–butyl–3–methyl imidazolium bromide ([BMIm]Br); 1–hexyl–3–methyl imidazolium bromide ([HMIm]Br) and 1–octyl–3–methyl imidazolium bromide ([OMIm]Br) ionic liquids on the miscibility of poly(vinyl pyrrolidone) and hydoxyethyl cellulose (PVP/HEC) blends were examined. The polymer solvent method was used to study miscibility of PVP/HEC blends. Two miscibility criterions on the based Δ[η] and ΔK were used to evaluate miscibility. Both Δ[η] and ΔK miscibility criterions confirmed that the PVP/HEC blends are miscible. PVP/HEC blends in the solid state were characterized with attenuated total reflective-Fourier transform infrared (ATR-FTIR) spectroscopy, differential scanning calorimetry (DSC) and field emission-scanning electron microscopy (FE-SEM). The miscibility of PVP/HEC blends was confirmed by ATR-FTIR, DSC and FE-SEM results. This miscibility was attributed to the strong intermolecular hydrogen bonding interactions between the –OH groups of HEC and –C = 0 groups of PVP.