III-V Interpeak Latencies Research Articles

Delayed brainstem auditory evoked responses in experimental diabetes mellitus.

The brainstem auditory evoked responses (BAER) were utilized for the evaluation of central neural transmission in alloxan-induced diabetes in rats. The mean latencies of waves I, III, V and the interpeak latencies III-V and I-V were prolonged in diabetic rats as compared to the same rats before alloxan administration. The incidence of abnormal BAER was more frequent in the group of rats with severe diabetes (82 per cent) than in mildly diabetic animals (42 per cent). Our results may suggest the presence of a central neuropathy in experimental diabetes, which can be detected by the method of BAER.

Age-related latency changes in the brain-stem auditory evoked potentials

The effects of age on the brain-stem auditory evoked potentials were studied on 156 healthy subjects with ages ranging from 18 to 76 years. The latencies of peaks I-VII and the interpeak latencies of I-III, III-V and I-V were consistently shorter for the female group than the male group. The female also had higher peak amplitude than the males. The effects of sex on the peak and interpeak latencies were observed in all age groups. There was a small progressive prolongation in the peak latency with increasing age, particularly peak V. Although a correlation between the age and the I-III interval was not observed, there was also a small increase with age in the interpeak latencies of III-V and I-V.

Brainstem auditory evoked potentials in chronic renal failure and maintenance hemodialysis.

Brainstem auditory evoked potentials (BAEPs) were recorded in 36 chronic uremic patients maintained on hemodialysis and in 10 normal controls. Both absolute response latencies and central transmission times were affected. There were transitory increases in interpeak latencies of I-II and III-V that were reversed by dialysis. A permanent increase in wave III-V interpeak latency was not reversed by dialysis. Wave II-III interpeak latency was unaffected.

ＡＢＲ対側記録と反応各波の分離同定について

Contralaterally recorded brainstem auditory evoked potentials were compared with ipsilaterally recorded ones in an attempt to apply their differences for wave identification. The method proved to be helpful in;1) identifying wave I, which is obscured on the contralateral, 2) separating waves IV and V, which are often more discrete contralaterally.But other contralateral findings such as;3) prolongation of waves II and V latencies, 4) lengthening of III-V interpeak latencies, 5) shortening of II-III interpeak latencies, seem to be of less clinical value, because the latency differences from each counterpart show a relatively wide distribution.