This study investigates the different ideological positions in news reportage on COVID-19 between April to August, 2020, reported on Citi TV, Joy News and TV3. The research examines lexical choices in the news that enact ideological positions following the assumptions of Critical Discourse Analysis (CDA) as the main instrument of analysis for the news reports. It became evident from the analysis that the ideological positioning in the three TV stations are represented differently. Whereas Citi TV tends to use lexical choices to minimize the seriousness of the pandemic, Joy News uses lexical choices to hold the government and stakeholders accountable to affected patients. Lexical choices used by TV3, on the other hand, employs words to appeal to Ghanaians to adhere to safety protocols by providing facts from credible sources. The news reports on COVID-19 demonstrates how the three TV stations reported on the same pandemic in vastly different ways through particular uses of lexicon that reflected their differing ideological positions and national interests.