more hypothetical sleep-related issues, were Sometimes it is useful to reflect on how things have focused on: agrypnia excitata, a final clinical manichanged and improved over time. If as a subscriber festation of three completely different conditions; and reader you are interested in having access to and, beta EEG activity in insomnia. state-of-the-art reviews on areas relevant to sleep Each issue of Volume 5 contained a Guest Eddisorders medicine, we trust you will appreciate itorial, written by a recognized authority in the the growth of Sleep Medicine Reviews (SMR) in our area, which provided the general context for the efforts to provide comprehensive coverage of our lead article or articles in each issue and often diverse and complex field. provided the additional insight of an expert point In 1997, SMR published Volume 1, which consisted of view that was not always in total agreement with of two issues, contained two regular editorials, one authors. Our editorial desire to provide a forum guest editorial and nine clinical review articles, for the controversial aspects to sleep medicine was totalling 122 pages published in A5 format. Five further illustrated in Volume 5 by two commentaries years later, in 2001, SMR Volume 5 consisted of written in response to reviews on idiopathic hysix issues containing one regular editorial, six persomnia and on beta EEG activity in insomnia, guest editorials, twenty-nine review articles, and which questioned some of the conclusions offered two letters to the editors, totalling nearly 500 by the authors of the initial reviews. The authors’ pages published in an enlarged A4 format. We replies to these commentaries nicely exemplify that thank our readership for their continued interest, sleep medicine is a developing field, that like any which has facilitated the growth of SMR, and trust that they are pleased with how the journal scientifically-based clinical effort, moves forward in an iterative, emperically based fashion. has matured. The majority of the reviews contained in Volume This theme, the battle of ideas, which ultimately advances the field, is carried forward into the cur5, a total of 20, are “state-of-the-art” clinical reviews. However, we also published seven phyirent, sixth, volume of Sleep Medicine Reviews. We introduce this year’s volume with a pair of reviews siological reviews and two theoretical reviews. The clinical review topics speak to the varied aspects of that take opposite positions on the question, “Should all sleep apnea patients be treated?” Dr. sleep medicine and include: outcome measures in sleep medicine practice and research; cognitive funcLevy and colleagues take the affirmative position to this question, while Dr. Montserrat and his coltion in sleep disorders; sleep apnoea-related issues, such as appropriate CPAP treatment and use of leagues argue the negative position. Each group also offers a reply to the position taken by the other. oral appliances; sleepiness and the law; secondary insomnia; yawning; sleeping sickness; restless leg Finally, Dr. Kryger offers his perspective in a Guest Editorial that provides commentary on these two syndrome; pain and sleep; circadian rhythms in the blind; sleep after surgery; and, idiopathic hyreviews and their respective replies. We hope our readers find this point and counterpoint both enpersomnia. The physiological reviews examined: the physiological bases of REM and NREM sleep; the joyable and thought provoking. Letters to the editor can also demonstrate the moment of falling asleep; how much sleep do we need; cognition–sleep relationships in animals and value of point and counter-point. We are pleased that the current issue contains such a contribution in humans; and, the molecular correlates of sleep and waking. The two theoretical reviews, examining from one of our readers, with a reply from the