ABSTRACT Hyperspectral thermal infrared (HTIR) data offers enormous potential for land surface temperature (LST) and emissivity (LSE) inversion. Methods to fully use a large amount of spectral information, while avoiding data redundancy, is constantly being explored. Therefore, a new framework for LST and LSE inversion using HTIR data is proposed in this study. First, the stepwise iteration method based on information content was used to select channels that were more sensitive to land surface information. Principal component analysis (PCA) and a two-step machine learning method were then used to retrieve the LST and LSE based on the selected channels. The findings demonstrate that the LST and spectra of the LSE can be obtained simultaneously based on the proposed framework. An LST inversion accuracy of 1.5K and an emissivity inversion accuracy of 0.017 can be achieved. However, an increase in the number of channels does not result in superior outcomes. Satisfactory inversion results can be obtained by selecting only 10–35 channels with the highest information content. In conclusion, this framework can be used to guide channel selection and land surface parameters inversion for HTIR sensors.