Unmanned aerial vehicles (UAVs), also known as drones, are a cost-effective alternative to traditional surveying methods, and they can be used to collect geospatial data over inaccessible or hard-to-reach locations. UAV-integrated miniaturized remote sensing sensors such as hyperspectral and LiDAR sensors, which formerly operated on airborne and spaceborne platforms, have recently been developed. Their accuracies can still be guaranteed when incorporating pieces of equipment such as ground control points (GCPs) and field spectrometers. This study conducted three experiments for geometric and radiometric accuracy assessments of simultaneously acquired RGB, hyperspectral, and LiDAR data from a single mission. Our RGB and hyperspectral data generated orthorectified images based on direct georeferencing without any GCPs. Because of this, a base station is required for the post-processed Global Navigation Satellite System/Inertial Measurement Unit (GNSS/IMU) data. First, we compared the geometric accuracy of orthorectified RGB and hyperspectral images relative to the distance of the base station to determine which base station should be used. Second, point clouds could be generated from overlapped RGB images and a LiDAR sensor. We quantitatively and qualitatively compared RGB and LiDAR point clouds in this experiment. Lastly, we evaluated the radiometric quality of hyperspectral images, which is the most critical factor of the hyperspectral sensor, using reference spectra that was simultaneously measured by a field spectrometer. Consequently, the distance of the base station for post-processing the GNSS/IMU data was found to have no significant impact on the geometric accuracy, indicating that a dedicated base station is not always necessary. Our experimental results demonstrated geometric errors of less than two hyperspectral pixels without using GCPs, achieving a level of accuracy that is comparable to survey-level standards. Regarding the comparison of RGB- and LiDAR-based point clouds, RGB point clouds exhibited noise and lacked details; however, through the cleaning process, their vertical accuracy was found to be comparable with LiDAR’s accuracy. Although photogrammetry generated denser point clouds compared with LiDAR, the overall quality for extracting the elevation data greatly relies on factors such as the original image quality, including the image’s occlusions, shadows, and tie-points, for matching. Furthermore, the image spectra derived from hyperspectral data consistently demonstrated high radiometric quality without the need for in situ field spectrum information. This finding indicates that in situ field spectra are not always required to guarantee the radiometric quality of hyperspectral data, as long as well-calibrated targets are utilized.