Hypersexuality Research Articles

Long-Term Administration of Testosterone Undecanoate Every 3 Months for Testosterone Supplementation in Female-to-Male Transsexuals

The most common treatment regimen in female-to-male transsexuals is administration of short-acting testosterone esters im every 2 wk. Our objective was to report the effects of administering long-acting testosterone undecanoate every 3 months on hormonal and clinical changes, mortality, morbidity, and safety during the first year of treatment in female-to-male transsexuals. This was a 1-yr observational study. The setting was an outpatient department at a university hospital. A total of 35 female-to-male transsexuals completed the first year of observation, whereas two patients discontinued the treatment regimen due to serious hypertension. The intervention was 1-yr im treatment with long-acting testosterone undecanoate every 3 months. Gonadotropins, steroid hormones, liver enzymes, lipids, blood and coagulation parameter, body mass index, blood pressure, bone mineral density, and endometrium thickness were measured at the beginning of cross-sex hormone treatment and after 12 months. The mortality, morbidity, adverse effects, and desired clinical changes were recorded. There was a significant decrease in LH, prolactin, SHBG, high-density lipoprotein levels, and endometrium thickness, and a significant increase in body mass index, systolic and diastolic blood pressure, total testosterone and calculated androgens, triglycerides, hemoglobin, and hematocrit levels. No mortality was observed. Two cases of hypertension were noted. The patients reported a desirable increase in libido and clitoral growth. Acne was observed in five patients (14.3%). The treatment of female-to-male transsexuals with long-acting testosterone undecanoate may be a feasible and safe option for testosterone augmentation in these subjects. However, monitoring of blood pressure should not be ignored during the treatment, to identify patients liable to develop hypertension.

Alcohol and drug consumption among sexual offenders

Purpose To evaluate the role of alcohol and drug consumption between sexual offenders against boys and girls. Method It was an observational, retrospective and cross-sectional study carried out by the Ambulatory for the treatment of sexual disorders of ABC Medical College, Santo André, São Paulo, Brazil (ABSex). The sample comprised 104 convicts, over 18 years old, sentenced only for sexual crimes against children (below 11 years old). Alcohol and drug consumption, sexual abuse history, sexual impulsivity, and risk of recidivism were evaluated. Results The sexual offenders against boys showed higher alcohol consumption problems than sexual offenders against girls ( χ 2 = 19.76, 1 d.f., p < 0.01). The severity of alcohol consumption was also significantly higher in the sexual offenders against non-related boys than in the sexual offenders against non-related girls ( p = 0.037, ANOVA). After adjustment for other variables, such as monthly income before the penalty and alcohol consumption at the moment of the crime, the alcohol consumption severity in sexual offenders against boys was significantly higher than in sexual offenders against girls (OR = 1.05, CI 1.01–1.08, p < 0.01). Conclusions Alcohol use or abuse is associated with the perpetration of sexual aggression. The role of alcohol consumption seems to be greater in sexual offenders against boys than in girls and this can contribute to criminal recidivism.

The Image of the Arabs in American Movies and Novels

The Image of the Arabs in American Movies and Novels This paper primarily discusses the various stereotypes and negative images of Arabs as presented in American movies & novels. Hollywood films often portray negative stereotypes and mistaken representations of almost every minority group in the world, among them, blacks, Asians, and Arabs. In this paper, it is argued that the Arab and Islamic cultures have been the most misunderstood and incorporate the nastiest stereotypes and distorted images. American movies & novels often stereotype Arabs in one of the famous 3 'B' categories: billionaires, bombers, or belly dancers. Many movies feature Arabs as wealthy men, driving limousines and using money to seduce women, or as terrorist villains threatening to blow things up. Arab women are portrayed in movies and fiction as exotic harem belly dancers who are characterless: mute, marginalized, and repressed. However, in literature, the picture is even bleaker as there exists a much greater degree of racism than that found in movies. In fiction, the Arab world is most often portrayed as a place swarming with Islamic fanatics, terrorists, sex maniacs and desert nomads, all with no cultural background. The paper will deal with some movies and novels selected on the basis of their being representative of the topic. The paper raises some questions about who is responsible for this distorted image, and it tries to find some answers around what the Arab world can do to promulgate its true values and culture around the world.

Oxcarbazepine Found to Reduce AD Hypersexuality

Oxcarbazepine Found to Reduce AD Hypersexuality

Hypersexuality Resolves With Oxcarbazepine

Hypersexuality Resolves With Oxcarbazepine

Hypersexuality in AD Resolves With Oxcarbazepine

Hypersexuality in AD Resolves With Oxcarbazepine

Review of Effective Interventions for Socially Inappropriate Masturbation in Persons with Cognitive Disabilities

Surveys of the sexual behaviors of persons with cognitive disabilities report as a main problem unacceptably displayed autoerotic behaviors that are appropriate in private, but inappropriate or illegal in public situations. Public or distractingly excessive masturbation is socially unacceptable and has been addressed with several successful interventions different in nature. This review of the literature investigates factors that lead to necessary intervention, identifies associations of different effective treatment approaches with types of cognitive disabilities, and examines the evolution of documented interventions from the late 1960s to the early 2000s. Data suggest that theoretical advances toward more humane, supportive and self-regulative interventions are more likely to help persons with milder cognitive disabilities. Self-regulation, or differentiated control over the public aspect of masturbatory behaviors is less likely to be accomplished in cases with more severe cognitive and social skill deficits. Ethical and legal questions of different treatment approaches are discussed.

P1-446: Safety & efficacy of oxcarbazepine in the treatment of hypersexuality in Alzheimer’s disease patients residing in a special care unit in an assisted living facility

P1-446: Safety & efficacy of oxcarbazepine in the treatment of hypersexuality in Alzheimer’s disease patients residing in a special care unit in an assisted living facility

The Relationship between Libido and Testosterone Levels in Aging Men

Although it is known that serum testosterone (T) concentrations are related to libido, the strength of that relationship in community-dwelling men has not yet been determined. Our objective was to assess the strength and significance of the association between aging men's self-reports of libido and serum T concentrations. Our study was a community-based evaluation of men's health and aging, including three data collection waves: baseline (T1, 1987-1989) and follow-ups (T2, 1995-1997; T3, 2002-2004). Libido was measured on a 14-point scale assessing self-reported frequency of desire and thoughts/fantasies; low libido was defined as a score of less than 7 of 14. We conducted an epidemiological study in greater Boston, Massachusetts. There were 1632 men aged 40-70 yr at baseline, with follow-up on 922 (56%) at 9 yr (T2) and 623 (38%) at 15 yr (T3). We assessed total and calculated bioavailable T . Three hundred eighteen (19%) subjects reported low libido at baseline. Libido and T displayed a significant association. However, the difference in mean T levels between those subjects with low libido and those without was small; analyses indicated a 3.4 ng/dl (0.12 nmol/liter) increase in total T per unit increase in libido. Subjects reporting low libido exhibited an increased but modest probability of exhibiting low T. Dividing T concentrations by the number of androgen receptor gene cytosine, adenine, guanine repeats did not enhance associations. Libido and T concentrations are strongly related at the population level. However, the value of individual patient reports of reduced libido as indicators of low T levels is open to question.

The Paraphilia‐Related Disorders: An Investigation of the Relevance of the Concept in Sexual Murderers*

Paraphilic disorders (PAs) and sexual preoccupation are known risk factors for recidivism in sexual offenders. Nonparaphilic sexual excessive behaviors-so-called paraphilia-related disorders (PRDs), like paraphilias, are also characterized by sexual preoccupation and volitional impairment and can be diagnosed in paraphilic men. The prevalence and clinical significance of PRDs in sexual homicide perpetrators, however, is unknown. We investigated the relationship between PAs and PRDs retrospectively in a sample of 161 sexual murderers. Four groups were compared: men without a PA or a PRD diagnosis, men with at least one PRD but no PA, men with at least one PA but no PRD, and finally, those with a combination of both (PA+PRD). The PA+PRD group had the most lifetime cumulative sexual impulsivity disorders, more developmental problems, the highest persistent frequency of sexual activity, the highest number of previous sexual offences, more sexual sadism, and compulsive masturbation. Men of the PRD subsample had suffered more from childhood sexual abuse, showed more promiscuity, psychopathy, and alcohol problems. The use of the PRD concept in this special offender group should be further investigated with prospectively designed studies.

A qualitative analysis of GHB use among gay men: Reasons for use despite potential adverse outcomes

This paper examines the use of gamma-hydroxybutyrate (GHB) among a sample of gay men in New York City, who identify GHB as their most frequently used club drug. The sample was drawn from a larger longitudinal investigation of club drug using men. Thematic analysis yielded findings regarding perceived stigma for GHB use, tolerance of potential adverse side effects, and reasons for why some prefer this substance to other club drugs. Specifically, our findings suggest that GHB is viewed unfavorably in many social circles, that side effects are tolerated by frequent GHB users, and that the drug is chosen over other substances because the short duration of action, energy boost, sleep assistance, increase in libido, and limited after-effects. Examining the reasons why men use this substance will lead to the development of GHB specific prevention strategies, which accurately address the consequences of use as well as the motivations that individuals possess for using the substance.

Obszöne Telefonanrufe - Beziehungen zu Paraphilien, Paraphilie verwandten Störungen und Stalking

Little is known about the aetiology, course and therapy of obscene telephone calls as a paraphilic behaviour. Overlaps to other paraphilias like voyeurism, paraphilia related disorders and the concept of stalking are reported in the literature. In case reports we describe the paraphilic development and course with a focus on the relationship to the victim. We discuss this on the background of different concepts regarding risk assessment and therapy.

Sex steroids and sexual desire in a man with a novel mutation of aromatase gene and hypogonadism

Sexual behavior was investigated by a sexological interview in a man with aromatase deficiency and hypogonadism. The study was performed at the end of a long testosterone treatment, during transdermal estradiol treatment and during estradiol and testosterone associated treatment. Sexual behavior did not show abnormalities. As assessed by a sexological interview and by a sexological questionnaire gender-identity was male, sexual orientation was heterosexual and libido was normal. Sexual function was limited to masturbation and was seemingly unaffected by testosterone or estradiol alone; only the associated treatment induced a great increase in libido and in frequency of masturbation and sexual fantasies when both testosterone and estradiol reached the range of normality. Sexual behavior is mainly under the control of cognitive functions in men, but sex steroids may modulate some aspects of male sexuality. Our findings suggest that in men estrogens could play a role in sexual activity.

Sexual addiction, sexual compulsivity, sexual impulsivity, or what? Toward a theoretical model

We critically review the concepts of sexual addiction, sexual compulsivity, and sexual impulsivity and discuss their theoretical bases. A sample of 31 self‐defined sex addicts was assessed by means of interview and questionnaires and compared with a large age‐matched control group. A tendency to experience increased sexual interest in states of depression or anxiety was strongly characteristic of the sex addict group. Dissociative experiences were described by 45% of sex addicts and may have some explanatory relevance. Obsessive‐compulsive mechanisms may be relevant in some cases, and the addiction concept may prove to be relevant with further research. Overall, results suggested that out of control sexual behavior results from a variety of mechanisms. We propose an alternative theoretical approach to investigating these mechanisms based on the dual control model and recent research on the relation between mood and sexuality.

P2-346 Safety and efficacy of oxcarbazepine in the treatment of hypersexuality in Alzheimer's disease patients residing in the community

P2-346 Safety and efficacy of oxcarbazepine in the treatment of hypersexuality in Alzheimer's disease patients residing in the community

Testosterone Cream Might Work for Female Sexual Dysfunction

Use of androgens to increase libido in women has been a favorite topic of discussion in the media. In this double-blind, placebo-controlled, crossover

Excessive masturbation after epilepsy surgery

Sexual behavior changes as well as depression, anxiety, and organic mood/personality disorders have been reported in temporal lobe epilepsy (TLE) patients before and after epilepsy surgery. The authors describe a 14-year-old girl with symptoms of excessive masturbation in inappropriate places, social withdrawal, irritability, aggressive behavior, and crying spells after selective amygdalohippocampectomy for medically intractable TLE with hippocampal sclerosis. Since the family members felt extremely embarrassed, they were upset and angry with the patient which, in turn, increased her depressive symptoms. Both her excessive masturbation behavior and depressive symptoms remitted within 2 months of psychoeducative intervention and treatment with citalopram 20 mg/day. Excessive masturbation is proposed to be related to the psychosocial changes due to seizure-free status after surgery as well as other possible mechanisms such as Kluver–Bucy syndrome features and neurophysiologic changes associated with the cessation of epileptic discharges. This case demonstrates that psychiatric problems and sexual changes encountered after epilepsy surgery are possibly multifactorial and in adolescence hypersexuality may be manifested as excessive masturbation behavior.

Hypersexual Desire in Males: Are Males With Paraphilias Different From Males With Paraphilia-Related Disorders?

The assessment of current sexual behavior (fantasies, urges, and activities) and sexual preoccupation (measured in min/day) associated with both conventional (i.e., adult relationship-associated) or unconventional (paraphilia and paraphilia-related) sexual behavior were ascertained from a sample of 120 consecutively evaluated males with paraphilias (PA; n = 88, including sex offender paraphiliacs; n = 60) and paraphilia-related disorders (PRD; n = 32). In addition, an assessment of hypersexual desire, defined as the highest sustained period (at least 6 months minimum duration) of persistently enacted sexual behavior (total sexual outlet/week [TSO] after age 15) was assessed. In almost all measures, the PA and PRD groups were not statistically significantly different. The average PA or PRD reported a mean hypersexual TSO of 11.7 +/- 7.3, a mean age of 21.6 +/- 7.1 years at onset of peak hypersexual behavior, and a mean duration of 6.2 +/- 7.6 years of hypersexual TSO. When the sample was stratified into three subgroups on the basis of the lifetime number of PAs + PRDs as a proxy measure of the severity of sexual impulsivity, the "high" group, with at least 5 lifetime PAs and PRDs, consisted of all paraphilic males, predominantly sex offenders, who self-reported the highest hypersexual desire (14.3 +/- 7.9), the highest current TSO/week (9.9 +/- 8.1), the most current sexual preoccupation (2-4 hr/day), and the highest likelihood of incarceration secondary to paraphilic sex-offending behavior. Although hypersexual desire, a quantitative measure of enacted sexual behaviours, may be a meaningful construct for clinically derived samples, the incidence and prevalence of hypersexual desire in community samples of males with paraphilias and paraphilia-related disorders is unknown.

Sex offending and sexual appetite: the clinical and theoretical relevance of hypersexual desire.

Disinhibited sexual desire, clinically manifested as hypersexual desire disorders, can be operationally defined by considering three behavioral domains associated with sexual motivation or appetitive behavior: (a) sexual preoccupation (time/day consumed by fantasies, urges, and activities), (b) the repetitive frequency of enacted sexual behavior (total sexual outlet/week), and (c) adverse consequences associated with repetitive sexual behavior: Data are presented suggesting that clinical samples of males with paraphilias, paraphilia-related disorders, and sexual coercion may be associated with disinhibited sexual appetite. These conditions need to be addressed by an integrated combination of psychotherapeutic and psychopharmacologic interventions that specifically target disinhibited sexual appetitive behaviors, their antecedents, and consequences. Although combination therapies (empirically based specific psychotherapies in conjunction with psychopharmacological treatments) have demonstrated superior efficacy in many Axis I psychiatric disorders, such combination therapies to reduce paraphilias, paraphilia-related disorders, and adult sexual coercion are currently underutilized in both North and South America and Europe.

Progesterone increase under DHEA-substitution in males

Two case reports of men suffering from excessive fatigue and depression are presented, both treated with 50 or 25 mg DHEA per day over a period of 1 year. Under DHEA treatment one subject reported being less tired and the other experienced improved well-being without depressive episodes and an increase in libido. Investigations of sex hormone parameters in plasma before and under treatment revealed a decrease of testosterone and an increase of progesterone in both, possibly dose-dependent to DHEA application. It is hypothesised that the increase of progesterone is parallel to an increase of its metabolite allopregnanolone (which was not determined), that might explain the improvement in well-being. The increase of progesterone under DHEA supplementation in males should receive further attention.