Hypercrosslinked Porous Polymer Research Articles

Facile synthesis of magnetic hyper-crosslinked porous polymer for efficient extraction and sensitive determination of nitroimidazole antibiotics

Antibiotics are a class of emerging organic pollutants that pose serious risk to human health and the environment. Nitroimidazoles (NDZs), as a group of important antibiotics, are widely used in livestock and poultry. However, their toxicity has caused world-wide public attention. Based on the idea of turning trash into treasure, in this study, a novel magnetic hyper-crosslinked polymer (M−HCP) was facilely synthesized via Friedel-Crafts reaction by crosslinking wasted polystyrene foam with 1,4-bis(chloromethyl)benzene in the presence of Fe3O4. The prepared M−HCP was characterized by scanning electron microscopy, transmission electron microscopy, Fourier-transform infrared spectroscopy, Brunauer-Emmett-Teller surface area and porosity measurements. The M−HCP showed a high adsorption ability for NDZs including ronidazole, secnidazole, dimetridazole and ornidazole. By coupling M−HCP based magnetic solid-phase extraction with high performance liquid-phase chromatography-ultraviolet detector, a sensitive method was developed for the determination of four NDZs in environmental water. Under optimal conditions, a good linearity was obtained in the range of 0.04–100 ng∙mL−1 with the correlation coefficients above 0.9993. Low limits of detection were achieved between 0.01 and 0.03 ng∙mL−1. The developed method was successfully applied to simultaneously determine four NDZs in environmental water, with recoveries from 94.0 % to 105 % and relative standard deviations below 4.8 %, demonstrating that the method has a good sensitivity and accuracy for the determination of NDZs in environmental water. This work not only provides a good alternative for effective detection of trace NDZs, but also has great significance in environment protection and sustainable development by conversing wastes into higher-value-added materials.

Fabrication of chitin based hydrophilic hyper-crosslinked porous polymer for efficiently removing bisphenol A from water

Water pollution caused by bisphenol A (BPA) has become the world problem. Designing and preparing cost-effective and biodegradable sorbents for the effectively adsorptive removal of bisphenol A from wastewater is of immense significance. Herein, a natural polysaccharide (chitin) was used as raw materials to be grafted with styrene (GS), then crosslinked with α,α'-dichloro-p-xylene (DCX) to form the hyper-crosslinked polymer (labeled as CGS@DCX). The CGS@DCX showed high adsorptive affinity for bisphenol A, with adsorption capacity of 441 mg g−1. Various studies gave an insight into the adsorption process, demonstrating that the highly efficient adsorption of BPA by the CGS@DCX is mainly based on the π-π stacking, hydrogen-bond interaction, polar interaction and pore adsorption. Moreover, the CGS@DCX had high chemical stability, good reusability (9 cycles) and fast adsorption kinetics (10 min) for adsorption of BPA. This work provides a promising strategy for the design and synthesis of novel yet eco-friendly sorbents to solve environmental problems.

Sulfonated hypercross-linked porous organic polymer based humidity sensor

Humidity sensors are of great significance in industry, agriculture and human activities, and many nanomaterials are already used for humidity sensing. Linear ionic polymers with hydrophilic groups have exhibited good humidity detection performance because they can adsorb water and then dissociate charged carriers. However, it suffers from the instability under high relative humidity that caused by polymer chain swelling and disengagement. To overcome this shortage, in this work, a new sensor based on hypercross-linked porous organic polymer (POP) with sulfonic acid group was fabricated to humidity detection in wide humidity range. The POP with strong covalent bonds exhibits remarkable chemical and thermal stability, and sulfonic acid group in the pore can act as fully accessible active site to enhance its ability to adsorb water. The obtained sensor shows high response (∼77) in a wide relative humidity range (11%−95% RH), short response/recovery time (9 s/21 s) and good stability. Complex impedance curves and density functional theory have been carefully investigated to understand its sensing mechanism. This work provides a new direction for the development of the impedance-type humidity sensitive materials in subsequent research and practical applications.

Preparation of hypercrosslinked porous polymer with manifold functional groups for sensitive determination of phenylurea herbicides in beverages and celtuce samples.

Wide use of phenylurea herbicide has caused serious residue problem and threaten human health. It is important to develop viable method for their sensitive determination. Herein, a multi-functionalized porous polymer was prepared by crosslinking hexafluorobisphenol A with pyromellitic dianhydride. Using the multi-functionalized porous polymer as solid phase extraction sorbent, combined with high performance liquid chromatography, a sensitive method was established for determining phenylurea herbicides in beverages and celtuces. High sensitivity was achieved, with method detection limit (S/N=3) of 0.01---0.025ngmL-1 for beverages, 1.70ngg-1 for celtuce, and quantitation limits of 0.03---0.10ngmL-1 for beverages, 5.00ngg-1 for celtuce. The method recoveries were 80.5---120.0 % with relative standard deviations lower than 6.1%. Adsorption mechanism mainly involved F-π, F-O, π-π, polar interactions and hydrogen-bonding interactions. This study offers a simple protocol to develop multi-functional sorbents for extraction of organic pollutants.

A novel phosphorylated hyper-crosslinked porous polymer for efficient uranium adsorption in water

As the nuclear resource industry rapidly progresses, efficient adsorbents play a vital role in separating and eliminating uranium from aqueous solutions. Herein, 9,9-dimethyl-fluorenylphosphonic acid was designed as a phosphate functional monomer and the triptycene as a rigid backbone monomer. Through the “knitting” strategy, a novel triptycene-based phosphorylated hyper-crosslinked porous polymer (TPP-DFP) was obtained by the above monomers. The resulted polymer TPP-DFP has a high BET surface area of 1397.62 m2/g with a rich porosity. The porous polymer TPP-DFP was the first time used for uranium adsorption from water and showed outstanding adsorption performance. The maximum uranium adsorption capacity of TPP-DFP was 414.26 mg/g, which was higher than that of most of other porous adsorbents. In the presence of impurity ions such as Ca2+, Mg2+, Al3+, Co2+, Ni2+, V5+, NO3−, CO32− etc., TPP-DFP exhibited high selectivity (Su up to 99%) for uranium. In addition, TPP-DFP has excellent reusability, and the removal percentage of uranium can reach more than 95% after 5 adsorption–desorption cycles. According to the XPS experiment, the mechanism of interaction between TPP-DFP and U(VI) was mainly due to the complex formed by the phosphate functional groups and U(VI). The theory DFT calculation indicated a 1:2 ratio of U(VI) and phosphate functional group on the two-distinct graft chain, which was consistent with the experimental results. Accordingly, the “knitting” polymerization technique showed potential for preparation effective adsorbents for uranium extraction from water.

Synthesis of cyano and ionic dual-functional hypercrosslinked porous polymer for effective adsorption and detection of endocrine disrupting chemicals in milk matrix

Endocrine disrupting chemicals (EDCs) can interfere with the normal function of endocrine system, posing serious risk to human health. The monitoring of EDCs in foods is of great importance to ensure food security. Herein, a cyano and ionic dual-functionalized hypercrosslinked porous polymer (CN-iHCP) was designed and prepared for the first time through hyper-crosslink of 1-(4-cyanophenyl)imidazole and 1,4-bis(chloromethyl)benzene. The adsorption mechanism mainly involves electrostatic interaction, hydrogen bonding and π-π stacking interaction. A sensitive analytical method for simultaneous detection of the four phenolic EDCs was established by coupled CN-iHCP based solid-phase extraction with high performance liquid chromatography. Under optimal conditions, the target EDCs exhibited good linearity with coefficient r > 0.993 and high enrichment factors of 164–243. The detection limits (S/N = 3) of EDCs were 0.20–0.50 ng mL−1 for milk sample. The extraction recoveries for the spiked milk samples were in the range of 85.5%− 116.0%. This work not only highlights the CN-iHCP as a promising adsorbent to efficiently enrich EDCs and other pollutants, but also provides a new strategy for the functionalization of HCP for wide applications.

Preparation and evaluation of a tryptophan based hypercrosslinked porous polymer as an efficient adsorbent for pipette tip solid-phase extraction of sulfonamides

A novel tryptophan-based porous polymer is designed and synthesized via a facile one-step hypercrosslinking polymerization process, and applied as sorbent for extraction of trace sulfonamides in foodstuffs. The developed polymer has high surface area, large conjugate system, and abundant functional groups (e.g., π-π stacking, hydrogen bonding, hydrophobic and electrostatic attraction interactions), which endow it with superior affinity and high adsorption capacity for sulfonamides (16.16–59.29 mg g−1). The optimized SPE method is coupled with HPLC-DAD to create a sensitive and efficient protocol that provides good linearity (R2 ≥ 0.9979), low limits of detection, satisfactory recoveries (92.5–109.5 %) and high precisions (RSDs < 8.24). In addition, the newly proposed method greatly reduces the amount of adsorbent (2.0 mg) and organic solvent (2.0 mL) used. Adsorption kinetics, isotherms, and simulation calculations studies further reveal the presence of monolayer adsorption, chemical adsorption process, and multiple interactions. Thus, this work presents a polymer capable of multiple interactions for the pretreatment of trace sulfonamides in foodstuffs.

Preparation of amino-functionalized triazine-based hyper-crosslinked polymer for efficient adsorption of endocrine disruptors

Herein, two novel amino-functionalized triazine-based hyper-crosslinked porous polymer (NH2-HCPs) (named as DPT-BB, DPT-DX) were designed and synthesized by direct crosslinking of 2,4-diamino-6-phenyl-1,3,5-triazine (DPT) with 4,4′-bis(chloromethyl)-1,1′-biphenyl (BB) or α, α′-dichloro-p-xylene (DX). Thanks to the amino functional group and hyper-crosslinked porous structure, NH2-HCPs displayed remarkable adsorption ability for phenolic EDCs. The adsorption mechanism mainly involved hydrogen bond, π-π interaction, hydrophobic interaction and pore filling. Thus DPT-BB was applied as solid phase extraction sorbent to extract phenolic EDCs from water and orange juice samples prior to quantitative analysis by high performance liquid chromatography. Under the optimal conditions, detection limit as low as 0.07–0.2 ng mL−1 for water and 0.1–0.27 ng mL−1 for orange juice was achieved. Good recoveries spanned the range of 83.5%–114% were obtained for spiked samples, with relative standard deviations below 8.9%. The results demonstrated that the developed method displayed excellent practicability for sensitive analysis of EDCs.

Converting waste expanded polystyrene into higher-value-added hyper-crosslinked porous polymer for rapid and high-efficient adsorption of aflatoxins

White pollution caused by the massive discharges of waste expanded polystyrene (WEPS) has become a critical global issue, so the effective conversion of WEPS is of great significance to reduce white pollution. Herein, adopting WEPS as raw material, three high-value-added hyper-crosslinked polymers (WEPS-HCPs) with high surface areas and abundant micro/mesoporous structures were synthesized via Friedel-Crafts alkylation reaction using dimethoxymethane, dichloroxylene and 4,4′-bis(chloromethyl)-1,1′-biphenyl (BCB) as cross-linker, respectively. The WEPS-HCPs were used as sorbent to extract aflatoxins (AFs) and all the HCPs exhibited high adsorption capacity. For the fast separation and recovery of the sorbent, WEPS-BCB was chosen as a model HCP to be magnetically functionalized to obtain a magnetic HCP (mWEPS-BCB) for the first time. Based on magnetic solid phase extraction with the mWEPS-BCB as sorbent, a fast and sensitive method was developed to determine trace level of AFs in grain food. Under the optimal conditions, the proposed method presented wide linear range (0.008–10.0 ng g−1), low detection limit (0.002–0.015 ng g−1) and satisfactory precision (relative standard deviation < 7%). Converting WEPS into a high-value-added sorbent not only provided a facile strategy for effective recycling of WEPS, but also developed a sensitive method for accurate determination of AFs in grain food, achieving significant economic and environmental benefits.

Upcycling of polyphenylene ether waste products to hypercrosslinked organic porous materials

Dimethyl phenol (DMP) oligomers are a side product of industrial poly(phenylethyl ether) (PPE) fabrication and significantly contribute to the environmental burden associated with PPE application. Here, a new process for the upcycling of waste-derived DMP into hyper-crosslinked porous polymer networks through Friedel-Crafts alkylation with p- dichloroxylene as an external crosslink agent is presented. The resulting hypercrosslinked porous polymers exhibited a maximum BET surface area of 740 m2/g and displayed and adsorption capacity of 5.9 wt% and 0.85 wt% towards CO2 (at 1.0 bar, 298 K) and H2 (at 1.0 bar, 77.3 K), respectively. Form stability of micro- and mesopores was attributed to the rigidity of the aromatic network structure. The results suggest new opportunities for the upcycling of DMP-waste components for applications such as carbon capture that could reduce the negative environmental const associated with the fabrication and application of PPE and related engineering polymers.

Efficient adsorption of methyl orange and methylene blue dyes by a novel carbazole-based hyper-crosslinked porous polymer

In this paper, a new type of carbazole-based hyper-crosslinked porous polymer (HCP-CP) was prepared through a very simple “knitted” method. The obtained novel polymer HCP-CP has a good adsorption property of methyl orange (MO) and methylene blue (MB) organic dyes in aqueous solution due to its high surface area and rich nitrogen atoms. The effect of pH, adsorption time, different initial concentration of dyes and adsorption reusability were investigated in detailed. The optimum pH is 8 for the adsorption of MB and 6 for the adsorption of MO, respectively. Under the best condition, the Langmuir model fitted the adsorption isotherm well and the adsorption behavior follow pseudo-second-order kinetics. The maximum adsorption capacity of HCP-CP for cationic dye MB (qmax=751.88 mg/g) is more than twice higher than that of anionic dye MO (qmax=274.73 mg/g). These capacity differences may be owing to the stronger electrostatic interaction between the negatively charged nitrogen atoms of HCP-CP with the cationic dye MB than that of MO. Moreover, the used polymer HCP-CP still retain a removal percentage above 92% after 5 times adsorption-desorption recycle. Therefore, this work provided a convenient synthetic route to develop a novel hyper-crosslinked polymer with high adsorption capacity for the entrapment of dyes from aqueous solution.

Selective hydrogenation via precise hydrogen bond interactions on catalytic scaffolds

The active site environment in enzymes has been known to affect catalyst performance through weak interactions with a substrate, but precise synthetic control of enzyme inspired heterogeneous catalysts remains challenging. Here, we synthesize hyper-crosslinked porous polymer (HCPs) with solely -OH or -CH3 groups on the polymer scaffold to tune the environment of active sites. Reaction rate measurements, spectroscopic techniques, along with DFT calculations show that HCP-OH catalysts enhance the hydrogenation rate of H-acceptor substrates containing carbonyl groups whereas hydrophobic HCP- CH3 ones promote non-H bond substrate activation. The functional groups go beyond enhancing substrate adsorption to partially activate the C = O bond and tune the catalytic sites. They also expose selectivity control in the hydrogenation of multifunctional substrates through preferential substrate functional group adsorption. The proposed synthetic strategy opens a new class of porous polymers for selective catalysis.

Highly efficient removal of uranium from aqueous solution by a novel robust phosphonic acid functionalized aromatic-based hyper-crosslinked porous polymer

Highly efficient removal of uranium from aqueous solution by a novel robust phosphonic acid functionalized aromatic-based hyper-crosslinked porous polymer

Synthesis of a porous amidoxime modified hypercrosslinked benzil polymer and efficient uranium extraction from water

Benzil was hypercrosslinked to produce a novel hypercrosslinked porous organic polymer skeleton (HCP-CO) with an ultrahigh Brunauer-Emmett-Teller (BET) surface area of 605.4 m2·g−1. The skeleton was grafted with diaminomaleonitrile (DAMN) via a simple Schiff base reaction, and then reacted with hydroxylamine hydrochloride (NH2OH·HCl) to produce an amidoxime-modified hypercrosslinked benzil polymer (HCP-AO) possessing many amidoxime groups. The chelation of the amidoxime group and uranium (VI) and porous structure provided HCP-AO with excellent adsorption performance. The maximum adsorption capacity for the uranium of HCP-AO can reach 370.9 mg·g−1 at pH = 6. Moreover, the adsorption process agreed well with the Langmuir and pseudo-second-order models, thus indicating it was monolayer chemical adsorption. HCP-AO demonstrated excellent selectivity and recyclability; furthermore, the removal rate for uranium still remained at 66.35% in the coexistence of metal ions in simulated seawater. Furthermore, after five adsorption–desorption cycles, the adsorption capacity of HCP-AO slightly reduced. To summarize, we synthesized an efficient adsorbent that possesses high adsorption capacity, selectivity, and recyclability; it has good potential for uranium extraction from water.

Efficient adsorption of methyl orange and methyl blue dyes by a novel triptycene-based hyper-crosslinked porous polymer.

It is still a great challenge to develop new materials for the highly efficient entrapment of organic dyes from aqueous solution. Herein, a novel triptycene-based hyper-crosslinked porous polymer (TPP–PP) was designed and synthesized by a simple Friedel–Crafts reaction. The obtained polymer TPP–PP has a high surface area, abundant pore structure and stable thermal performance. Due to the above characteristics, TPP–PP has good adsorption performance for anionic methyl orange solution (MO) and cationic methyl blue solution (MB). Under the optimal experiment conditions, the TPP–PP showed an excellent adsorption capacity for MO (220.82 mg g−1) and MB (159.80 mg g−1), respectively. The adsorption kinetics fitted the pseudo-second-order model. The adsorption of MO by TPP–PP reaches equilibrium within 180 minutes, and the adsorption of MB reaches equilibrium within 150 minutes. The adsorption behavior was not only spontaneous but also endothermic in reality. At the same time, TPP–PP also has good reusability. After 5 cycles of experiments, the removal rate of MO and MB by TPP–PP can still reach more than 80%. Thus, the Friedel–Crafts reaction crosslinked method might be a promising approach for the synthesis of novel material for the highly efficient extraction of dye wastewater.

A mesoporous polymer bearing 3D-Triptycene, –OH and azo- functionalities: Reversible and efficient capture of carbon dioxide and iodine vapor

Coal-fired power plants are the highest contributors to global electricity generation. Flue gases from thermal power plants are rich in carbon dioxide. Thus, thermal plants also contribute substantially to the annual increase in the concentration of atmospheric CO 2 (greenhouse gas) which in turn leads to increased global warming and ocean acidification. Solutions to these problems are either capture of carbon dioxide from flue gas or exploring alternative sources of power generation such as nuclear energy. However, volatile radioactive byproducts produced in nuclear plants need to be arrested by a suitable adsorbent. Herein, for the first time, we report a triptycene-based hypercrosslinked porous polymer ( TBHCP-OH ) that contains CO 2 -philic groups (–OH and –N N–). It was obtained using a simple Friedel–Crafts alkylation reaction. Mesoporous TBHCP-OH has high CO 2 capture capacity (87.6 mg/g) and excellent iodine vapor uptake capacity (2600 mg/g). This iodine uptake capacity is the highest among all triptycene based polymers reported till date. This may be attributed to the ample supramolecular interactions between arene/heteroatoms (O and N in TBHCP-OH ) and iodine. The facile and simple synthesis of TBHCP-OH as well as its ability to efficiently capture pollutants renders it a promising material for environmental remediation. • Design of a new triptycene based monomer with active CO2-philic (–N N– and –OH) and N2-phobic (azo) groups. • Facile synthesis of a mesoporous triptycene polymer ( TBHCP-OH ) with azo and phenolic functionalities via knitting strategy. • TBHCP-OH shows high CO 2 uptake of 8.76 wt.% at 273 K and 1 bar pressure which is comparable with monoethanolamine. • TBHCP-OH selectively captures CO 2 over N 2 at 1 bar which improves at higher temperature [273K (23) and 298 K (28)]. • High I 2 vapor adsorption capacity of TBHCP-OH (up to 2600 mg/g) is best among triptycene based polymers.

BiOBr/PBCD-B-D dual-function catalyst with oxygen vacancies for Acid Orange 7 removal: Evaluation of adsorption-photocatalysis performance and synergy mechanism

The fabrication of a dual-function material is an effective strategy to promote the degradation of pollutants through the synergy of adsorption and photocatalysis. Herein, we introduce an amphiphilic hyper-crosslinked porous cyclodextrin polymer (PBCD-B-D) into bismuth oxide bromide (BiOBr) via a one-pot solvothermal method to construct three-dimensional (3D) spherical flower-shaped BiOBr/PBCD-B-D (BOP) composites for removing the organic dye Acid Orange 7 (AO7). The prepared BiOBr composite loaded with 24% PBCD-B-D (BOP-24) displayed an optimal adsorption–photocatalytic effect. Under different concentration gradients, the pseudo first-order reaction rate constant of BOP-24 was 2–5 times that of BiOBr after visible-light irradiation. The unique cavity structure of PBCD-B-D resulted in a strong inclusion ability, which could concentrate organic pollutants and shorten the mass transfer distance. The introduction of PBCD-B-D to BiOBr led to an increase in the specific surface area and pore volume, which not only provided a large number of adsorption sites and active centers but also produced oxygen vacancies to improve charge separation. In addition, a possible degradation pathway was proposed for AO7 based on 3D excitation-emission matrix fluorescence spectra and analysis by liquid chromatography-mass spectrometry. This work combines the advantages of both adsorption and photocatalytic technologies for environmental remediation, and opens an avenue for dual-function high-surface-area adsorbent/photocatalysts via a one-pot in situ method.

Direct synthesis of oxygenates via partial oxidation of methane in the presence of O2 and H2 over a combination of Fe-ZSM-5 and Pd supported on an acid-functionalized porous polymer

Aqueous-phase partial oxidation of methane over a combination of heterogeneous Fe-ZSM-5 and Pd catalysts was demonstrated in the presence of O2 and H2. Fe-ZSM-5 catalyst active for partial oxidation of methane with H2O2 was prepared by an ion-exchange method. For comparison, homogeneous Fe species (FeSO4) were also used as a catalyst for partial oxidation of methane. Several supported Pd catalysts for the direct synthesis of hydrogen peroxide from H2 and O2 were prepared using activated carbon (AC), AC treated with sulfuric acid (s-AC), as-synthesized hyper-crosslinked porous polymer (HCPP), HCPP with carboxylic group (c−HCPP), and HCPP with carboxylic and sulfonic groups (c-s−HCPP). Among them, the Pd catalyst supported on c-s−HCPP was effective for generating H2O2in situ, which enabled methane oxidation over Fe-ZSM-5 without any leaching.

Thickness controllable hypercrosslinked porous polymer nanofilm with high CO2 capture capacity

Thickness controllable porous polymer nanofilm with superior gas storage capacity has gradually emerged as promising adsorbents for capture of CO2, due to extremely high surface area and micro-scale pore. In this work, we have developed a novel and facile strategy to fabricate thickness controllable two or three dimensional ordered porous nanofilm based on poly(styrene-butyl acrylate), in combination with covalently layer by layer (LBL) self-assemble process and hypercrosslinked post-treatment. Abundant microporous structures and a small number of mesoporous structures are formed in hypercorsslinked nanofilm and corresponding surface area derived from Brunauer-Emmett-Teller method (BET) were determined to be 605.7 m2/g. The capacity of CO2 capture was also measured, which reach up to 53.6 wt% (12.2 mmol/g) at 273 K/1 bar, which is comparable to highest record. We have found that all the as prepared nanofilm with different thickness exhibited apparently enhanced micro- and meso-porosity after hypercrosslinking. Moreover, with the increase of thickness of nanofilm, the adsorption capacity decreases gradually, as well as the CO2 adsorption capacity. An excellent recycling capacity for CO2 capture have also found for this porous polymer nanofilm via repetitive adsorption-desorption assay. Our work confirmed that thickness controllable porous polymer nanofilm with superior CO2 capture capacity can be fabricated by a very simple strategy which can meet the challenges of the current CO2 capture and storage technology.

Amphiphilic hyper-crosslinked porous cyclodextrin polymer with high specific surface area for rapid removal of organic micropollutants

Amphiphilic hyper-crosslinked porous cyclodextrin polymer (PBCD-B-D) with a surface area of 1445 m2 g−1 was synthesized for rapid removal of organic micropollutants. Partially benzylated cyclodextrin was crosslinked with 4,4′-bis(chloromethyl)-1,1′-biphenyl and α,α'-dichloro-p-xylene by the Friedel–Crafts alkylation reaction. The hydrophilicity of the PBCD-B-D surface is modulated by controlling the number of hydroxyl groups on cyclodextrin. Benzylation reaction is more likely to occur at the C-2 and C-6 positions of cyclodextrin hydroxyl groups according to Gaussian computation. Four different water-soluble pollutants (3-phenylphenol, 2-naphthol, p-nitrophenol, and 4-chlorophenol) were selected for adsorption study. The adsorption rate of PBCD-B-D is extremely high, and the removal efficiency reaches above 95% in 1 min. For the adsorption of 3-phenylphenol and 2-naphthol, the rate constants of PBCD-B-D are 827–1187 and 396–413 times larger than those of granular activated carbon (GAC) and β-cyclodextrin polymer crosslinked with epichlorohydrin (EPI-CDP), respectively. The adsorption capacity of PBCD-B-D is 2 and 4 times higher than that of GAC and EPI-CDP, respectively. The combination of cyclodextrin inclusion mechanism, hydrophobic attraction, and hydrogen bonding allows PBCD-B-D to adsorb both hydrophobic and hydrophilic pollutants. PBCD-B-D can be easily regenerated at room temperature using methanol as eluent. In addition, PBCD-B-D showed excellent adsorption performance towards mixed pollutants at environmentally relevant concentrations. According to the thermodynamic study, the adsorption of organic compounds onto PBCD-B-D belongs to physical adsorption and is spontaneous. PBCD-B-D is a potential novel adsorbent for water treatment owing to its excellent adsorption performance, low cost, and good regenerability.