Hydrophilic Filler Research Articles

Enhancement of the Reinforcement Effect of Calcium Carbonate or Silica on Natural Rubber Using Lauryl Alcohol

Calcium carbonate (CaCO3) and silica are two types of additives for rubber. Through the implementation of a typical semi-efficient (Semi-EV) vulcanisation formulation, those additives were added separately into the compound of natural rubber (NR). The CaCO3 or silica was added as the reinforcing filler and, incorporated into NR at a constant concentration i.e., 30 parts per hundred NR (phr). It was found that the CaCO3 or silica have successfully provided an increase in mechanical properties including a greater tensibility (tensile strength) and abrasion resistance of the compound of NR. However, as hydrophilic fillers, the CaCO3 or silica is hard to disperse homogeneously and hence, lauryl alcohol was used to improve their dispersion degrees. It was combined into the NR compound with varied concentrations such as 1, 3, 5 and 7 phr. Therefore, the effect of lauryl alcohol concentration on the processing and reinforcement properties of CaCO3 or silica-filled NR was investigated. It could be found that lauryl alcohol has increased the rate coefficient of vulcanisation (Rv) of the CaCO3 or silica-filled-NR. The greater the lauryl alcohol concentration; the greater the Rv value, tensile strength, and abrasion resistance. Overall, lauryl alcohol has a successful function as a plasticizing agent which increased the reinforcement effects of the fillers on NR through the increasing of crosslink density of CaCO3-NR or silica-NR especially at the 5 phr of addition.

Hydrophilic Cu-Graphene Heterostructure Fillers for the Enhancement of the Thermal Performance of Poly(vinyl Alcohol)-Based Composites

Hydrophilic Cu-Graphene Heterostructure Fillers for the Enhancement of the Thermal Performance of Poly(vinyl Alcohol)-Based Composites

Diaphragm and Membrane for Alkaline Water Electrolysis with Zirconium Hydroxide Hydrogel as Hydrophilic Filler

Diaphragm and Membrane for Alkaline Water Electrolysis with Zirconium Hydroxide Hydrogel as Hydrophilic Filler

Improving flame resistance and shielding properties for cross-linked polyethylene (XLPE) using nanoclay filler

Polymers play an essential role in both industry and medical fields due to their diverse and adaptable properties. In this work, prepared crosslinking polyethylene (XLPE) samples with hydrophilic bentonite nanoclay fillers (H2Al2O6Si) at concentrations of 0, 1, 2.5, 4, and 5 wt% enhance their flame-retardant and radiation shielding efficiency. The research investigated flame retardancy and thermal stability parameters. The XLPE/H2Al2O6Si nanocomposite polymer sheets were exposed to a collimated beam of fast neutrons using an Am/Be neutron source (5 Ci) and to gamma radiation using a 137Cs point source (5 μCi) to assess their radiation shielding properties. The study found that uniform dispersion of nanoclay particles enhanced the thermal properties of the composite, forming a char layer that acted as a barrier, slowing thermal decomposition and reducing the heat release rate. Limiting oxygen index (LOI) increased from 28% to 34%, and burning rate improved with higher nanoclay concentrations. Additionally, absorption and optical band gap calculations decreased with increasing filler concentrations. Radiation attenuation capabilities increased by approximately 40% for neutrons and 30% for gamma radiation compared to pure XLPE. The study concluded that incorporating nanoclay fillers into XLPE enhances its shielding capabilities and improves flame resistance properties, making the prepared samples suitable for various industrial applications.

Dual synergies of functionalized hydrophilic MOFs based poly (aryl ether ketone sulfone) ultrafiltration membranes: Electrostatic action and pore size screening

In this paper, amino monomer (4Am-PH) and the sulfonated poly (arylene ether ketone sulfone) involving amino groups (Am-SPAEKS) were successfully prepared by diazotization reaction and direct polycondensation, respectively. The polyethyleneimine-modified UiO-66-NH2 (P-MOFs) were prepared as fillers. Composite membranes were fabricated by incorporating different contents of P-MOFs into Am-SPAEKS polymer matrix using non-solvent-induced phase separation. The morphology, chemical structure and properties of the polymers, fillers and composite membranes were proved by FT-IR, 1H NMR, FE-SEM, XPS and etc. The final experimental results showed that the introduction of hydrophilic fillers, P-MOFs, substantially improved the hydrophilicity, water flux and antifouling capabilities of the membranes. The water contact angle decreased from 78.5° to 56.4°. The flux of water from a pure membrane was 333.68 L/m2 h. When the content of P-MOFs was 0.1 %, the water flux could attain to 830.23 L/m2 h, the retention rate of bovine serum albumin (BSA) solution could attain to 98.6 % and the flux recovery rate (FRR) values of the composite membrane remained high (86.1 %) for BSA solution. In addition, after three cycles, the pure water flux of the composite membrane could still attain 595.49 L/m2 h. The results demonstrated that P-MOFs have significant potential for utilization in the preparation of composite ultrafiltration membranes and provided an effective idea for the modification and design of other hydrophilic MOFs applied in the study area of ultrafiltration membranes.

Building extra transport channels in mixed-matrix membrane for air dehumidification

Membrane separation is a promising technology relative to the mature distillation technique due to its high energy efficiency. Incorporating nanoparticle to polymer matrix to fabricate mixed-matrix membranes (MMMs) is one of effective ways to overcome the typical trade-off relationship between gas permeability and selectivity. Although silica based MMMs were studied for natural gas dehydration and desalination, it is rarely been investigated for air dehumidification. Herein, membrane material with high water vapor affinity of Pebax 1074 was applied as polymer matrix and silica was incorporated as filler to fabricate MMMs. The embedded silica filler can simultaneously enhance water vapor permeability (13–33% up) and H2O/N2 selectivity (40–60% up) at an optimal loading of 1 wt%. The relatively hydrophobic form improved water vapor permeability due to the pronounced enlarged d-spacing and the resultantly enhanced diffusivity coefficient. The more hydrophilic filler enhanced more H2O/N2 selectivity than that of the counterpart because of the largely improved water vapor solubility coefficient. The concomitant improvement of both water vapor permeability and its selectivity makes it stand out from the various previously reported membranes, demonstrating its potential for scale-up application.

Directional drying of a colloidal dispersion: quantitative description with water potential measurements using water clusters in a poly(dimethylsiloxane) microfluidic chip.

We have developed a poly(dimethylsiloxane) (PDMS) microfluidic chip to study the directional drying of a colloidal dispersion confined in a channel. Our measurements on a dispersion of silica nanoparticles once again revealed the phenomenology commonly observed for such systems: the formation of a porous solid with linear growth in the channel at short times, slowing down at longer times as the evaporation rate decreases. The growth of the solid is also accompanied by mechanical stresses that are released by the delamination of the solid from the channel walls and the formation of cracks. In addition to these observations, we report original measurements using hydrophilic filler in the PDMS formulation used (Sylgard-184). When the PDMS matrix is in contact with water, water molecules pool around these hydrophilic sites, resulting in the formation of microscopic water clusters whose size depends on the water potential ψ. In our work, we have used these water clusters to estimate the water potential profile in the channel as the porous solid grows. Using a transport model that also takes into account solid delamination in the channel, we then linked these water potential measurements to the hydraulic permeability of the porous solid. These measurements finally enabled us to show that the slowdown in the evaporation rate is due to the invasion of the porous solid by air/water nanomenisci at a critical capillary pressure ψcap.

Development of Hydrophilic Oxide/Polymer Composite Membranes for Polymer Electrolyte Fuel Cells Operating at Wide Temperature Range

Toward the wide-spread use of heavy-duty vehicles (HDVs) operated by polymer electrolyte fuel cells (PEFCs) should approach the higher temperature around 120oC besides normal temperature (60-80oC). Commercial perfluorosulfonic acid-based electrolyte (PFSA, e.g. NafionⓇ) shows better proton conductivity with chemical stability in wide temperatures range, though decreases under low back pressure at 100~120 oC. In order to improve the proton conductivity at the higher temperature range, composite membrane of NafionⓇ with a hydrophilic filler of Ta doped TiO2 (Ta-TiO2) was synthesized. The Ta-TiO2 nanoparticles fillers with fused-aggregate network microstructure were synthesized by the flame method, and were crushed by wet mill(Star Burst, :Sugino Machine Limited CO.). The fillers were mixed with NafionⓇsolution (20 wt.%：D2020 Chemours Co.) by use of a rotary ultrasonic dispersing processor (500 rpm, 60 min. PR-1 :Thnky Co.), a planetary ball mill (500 rpm、30 min.：PULVERISETTE 6：FRITSCH Co.), and a defoaming processor (500 rpm、5 min.：HM-400W: Kyouritu Seiki). The dispersion solution was coated in hot air by use of a die coating system (die coater: Taku-Dai Mini-50: Daimon Co., Ltd.), and were hot-pressed (140 ℃ 3 min. TCMD-2.5:TOHO KOGYO co.) to form composite membranes (9 cm×9 cm ×25 µmt).The cross-sectional backscattered electron image BSE) of the composite membrane observed by scanning electron microscope (SEM, acceleration voltage 2 kV, SU9000: Hitachi High-Tech Co.) and transmission electron microscope (TEM, H-9500: Hitachi High-Tech Co.). The proton conductivity of the composite membrane was measured by the AC four-probe method. The current-voltage (IV) polarization curves of Single cells using the prepared composite membrane (membrane thickness: 25 µm) were measured at 80 ℃ 100% RH and 120 ℃ 20% RH, back pressure 50 kPaG.The obtained composite membranes were well flexibility with softness. The BSE images indicated that the high contrast images of Ta-TiO2 parties were uniformly dispersed in composite membrane. The higher magnified of the cross-sectional TEM images also showed that the hydrophilic surface of Ta-TiO2 adhered to the Nafion® without any air pores. The proton conductivity of the composite membrane at 80% RH increased with increasing Ta-TiO2 content and showed maximum value of 0.13 S cm-1at 3 wt%, and then decreased. The maximum proton conductivity was 1.3 times higher than that of Nafion®. The IV performance of the single cell using composite membrane kept same performance to that using Nafion® membrane at 80 oC 100% RH, and then improved at 120 oC 20% RH. The water content at 120 oC 20% RH kept higher value by the effect of hydrophilicity of the Ta-TiO2, which would be one of the reasons to enhance the cell performance at 120 oC 20% RH. Figure 1

Study on the Migration Behaviors of Magnesium Oxysulfate Nano-Whiskers in Polypropylene Composites with Surface Modification.

In this study, surface modification aimed to enhance the compatibility between a hydrophilic inorganic filler and polypropylene (PP) matrix using hydrophobic treatment. Lauric acid, butyl acrylate, and maleic anhydride were employed to modify the filler surface. After treatment, inorganic filler/PP composites were produced using melt-mixing and extrusion-injection molding processes. The study focused on investigating compatibility and migration behavior between the filler and matrix. The findings indicated that hydrophobic modification, specifically with butyl acrylate and maleic anhydride, improved migration issues in nano-whisker, while maintaining favorable mechanical properties even under accelerated thermal aging. However, excessive hydrophobicity induced by superhydrophobic treatment using lauric acid led to reduced compatibility with the matrix, compromising its effectiveness. Consequently, the study revealed the potential of surface modification to enhance interfacial properties and mitigate migration concerns in PP composites for automotive applications.

Green synthesis of sulfonated cellulose/polyether block amide/polyethylene glycol diacrylate (SC/PEBAX/PEGDA) composite membrane by gamma radiation and sulfonation techniques for battery application

Sulfonated cellulose (SC) was successfully prepared through a two-step process of gamma radiation and subsequently sulfonation with potassium metabisulfite of microcrystalline cellulose extracted from sugarcane bagasse. The effect of gamma radiation dose on cellulose showed an increment of oxidation degree, which was evidenced by the intensity ratio of I1718 (carbonyl)/ I2892 (aliphatic) from FTIR analysis. The obtained SC was introduced into polyether block amide/polyethylene glycol diacrylate (PEBAX/PEGDA) polymer matrix as a reinforcement and hydrophilic filler for improving electrolyte affinity and thermal stability of its composite membrane. The increase of SC in PEBAX/PEGDA composite membranes resulted in enhancement of hydrophilicity, electrolyte uptake, and thermal stability compared to pristine composite membranes. However, the excess SC content in the composite membrane exhibited the low physical properties, caused by negligible dispersion on the surface membrane. With the optimum 2.0 wt% SC in PEBAX/PEGDA, the porosity, contact angle and electrolyte uptake capacity was found to be 64.0 %, 12.8° and 37.5 %, respectively. 2.0 wt% SC/PEBAX/PEGDA showed the outstanding thermal stability with negligible shrinkage <10 % at 150 °C whereas pristine PEBAX/PEGDA showed the shrinkage of 29 %. The obtained SC/PEBAX/PEGDA composite membrane is considered as a potential candidate to replace the commercial polyolefin-based separator in lithium-ion batteries.

English

Starch fillers were extracted from three plant sources namely amora tuber, Tacca lentopeteloides; sweet potato, Ipomoea batatas; yam starch, Dioscorea rotundata and their particle size, pH, amylose, and amylopectin percentage decomposition determined accordingly. The starch was introduced into natural rubber in liquid phase (through gelatinization) by the latex compounding method and compounded according to standard method. The prepared starch/natural rubber composites was characterized by Instron Universal testing machine (UTM) for tensile mechanical properties. The composites was further characterized by x-ray diffraction and crosslink density analysis. The particle size determination showed that amora starch granules has the smallest particle size (156 &times; 47 &mu;m) followed by yam starch (155 &times; 40 &mu;m) and then sweet potato starch (153 &times; 46 &mu;m) with the biggest particle size. The pH test also revealed that amora starch has a near neutral pH of 6.9, yam 6.8, and sweet potato 5.2 respectively. Amylose and amylopectin determination showed that yam starch has a higher percentage of amylose (29.68), followed by potato (22.34) and then amora starch with the lowest value (14.86) respectively. The tensile mechanical properties testing revealed that yam starch produced the best tensile mechanical properties followed by amora starch and then sweet potato starch. The structure, crystallinity/amorphous nature of the product composite was confirmed by x-ray diffraction, while the nature of crosslinking was confirmed by swelling test in toluene solvent using the Flory-Rehner approach. The increasing values of crosslink density in the starch/rubber composite is a clear evidence of good interfacial adhesion between the starch fillers and the rubber, hence good dispersion of starch fillers in the rubber. This research has rendered a workable strategy for enhancing interfacial interaction between a hydrophilic filler (Starch) and hydrophobic polymeric matrix (natural rubber) yielding moderately good tensile mechanical properties with prospects for the rubber processing industry. The studied fillers can partially replace carbon black as natural rubber fillers with reduced cost, no risk to human health and also an environment friendly approach. Key words: Natural rubber, fillers, starch, amylose, amylopectin, crosslink density, mechanical properties.

ZnO/PDA/Mesoporous Cellular Foam Functionalized Thin-Film Nanocomposite Membrane towards Enhanced Nanofiltration Performance.

Thin-film nanocomposite (TFN) membranes are the third-generation membranes being explored for nanofiltration applications. Incorporating nanofillers in the dense selective polyamide (PA) layer improves the permeability-selectivity trade-off. The mesoporous cellular foam composite Zn-PDA-MCF-5 was used as a hydrophilic filler in this study to prepare TFN membranes. Incorporating the nanomaterial onto the TFN-2 membrane resulted in a decrease in the water contact angle and suppression of the membrane surface roughness. The pure water permeability of 6.40 LMH bar-1 at the optimal loading ratio of 0.25 wt.% obtained was higher than the TFN-0 (4.20 LMH bar-1). The optimal TFN-2 demonstrated a high rejection of small-sized organics (>95% rejection for 2,4-dichlorophenol over five cycles) and salts-Na2SO4 (≈95%) > MgCl2 (≈88%) > NaCl (86%) through size sieving and Donnan exclusion mechanisms. Furthermore, the flux recovery ratio for TFN-2 increased from 78.9 to 94.2% when challenged with a model protein foulant (bovine serum albumin), indicating improved anti-fouling abilities. Overall, these findings provided a concrete step forward in fabricating TFN membranes that are highly suitable for wastewater treatment and desalination applications.

Modification of Epoxy Compositions by the Application of Various Fillers of Natural Origin.

A series of composites based on epoxy resin filled with additives of natural origin were prepared to investigate the influence of such fillers on the properties of the epoxy compositions. For this purpose, the composites containing 5 and 10 wt.% of additive of natural origin were obtained using the dispersion of oak wood waste and peanut shells in bisphenol A epoxy resin cured with isophorone-diamine. The oak waste filler had been obtained during the assembly of the raw wooden floor. The performed studies include testing of samples prepared using unmodified and chemically modified additives. Chemical modification via mercerization and silanization was performed to increase the poor compatibility between the highly hydrophilic fillers of natural origin and the hydrophobic polymer matrix. Additionally, the introduction of NH2 groups to the structure of modified filler via 3-aminopropyltriethoxysilane, potentially takes a part in co-crosslinking with the epoxy resin. Fourier Transformed Infrared Spectroscopy (FT-IR), as well as Scanning Electron Microscopy (SEM), were carried out, to study the influence of performed chemical modification on the chemical structure and morphology of wood and peanut shell flour. SEM analyses showed significant changes in the morphology of compositions with chemically modified fillers, indicating improved adhesion of the resin to lignocellulosic waste particles. Moreover, a series of mechanical (hardness, tensile strength, flexural strength, compressive strength, and impact strength) tests were carried out, to assess the influence of the application of fillers of natural origin on the properties of epoxy compositions. All composites with lignocellulosic filler were characterized by higher compressive strength (64.2 MPa-5%U-OF, 66.4%-SilOF, 63.2-5%U-PSF, and 63.8-5%SilPSF, respectively), compared to the values recorded for the reference epoxy composition without lignocellulosic filler (59.0 MPa-REF). The highest compressive strength, among all tested samples, was recorded for the composite filled with 10 wt.% of unmodified oak flour (69.1 MPa-10%U-OF). Additionally, higher values of flexural and impact strength, concerning pure BPA-based epoxy resin, were recorded for the composites with oak filler (respectively, flexural strength: 73.8 MPa-5%U-OF and 71.5 MPa-REF; impact strength: 15.82 kJ/m2-5%U-OF, 9.15 kJ/m2-REF). Epoxy composites with such mechanical properties might be considered as broadly understood construction materials. Moreover, samples containing wood flour as a filler exhibit better mechanical properties compared to those with peanut shell flour (tensile strength for samples containing post-mercerization filler: 48.04 MPa and 40.54 MPa; while post-silanization 53.53 MPa and 42.74 MPa for compositions containing 5 wt.% of wood and peanut shell flour, respectively). At the same time, it was found that increasing the weight share of flour of natural origin in both cases resulted in the deterioration of mechanical properties.

Caffeine–Acrylic Resin DLP-Manufactured Composite as a Modern Biomaterial

Materials based on photocurable resins and pharmaceutically active agents (APIs) are gaining interest as a composite drug delivery system. In this study, a composite of caffeine with acrylic resin was obtained using an additive manufacturing method of digital light processing (DLP) as a potential material for transdermal drug delivery. The mechanical properties of the composites and the ability to release caffeine from the resin volume in an aqueous environment were investigated. The amount of caffeine in the resulting samples before and after release was evaluated using a gravimetric method. The global thresholding method was also evaluated for its applicability in examining caffeine release from the composite. It was shown that as the caffeine content increased, the strength properties worsened and the ability to release the drug from the composite increased, which was caused by negligible interfacial interactions between the hydrophilic filler and the hydrophobic matrix. The global thresholding method resulted in similar caffeine release rate values compared to the gravimetric method but only for samples in which the caffeine was mainly located near the sample surface. The distribution of caffeine throughout the sample volume made it impossible to assess the caffeine content of the sample using global thresholding.

Porous liquid metal-organic frameworks with selectively high gas solubility

Porous liquid metal–organic frameworks (MOFs) have recently been discovered rather promising for gas absorption and separation in practical chemical industry processes. In this work, we successfully fabricated a kind of MOF-based porous liquid (i.e., UIO-66-PL) by dispersing the hydrophilic porous filler of UIO-66-NH2 nanoparticles into a specific hydrophilic ionic liquid (IL, [HEMIM][DCA]) through the wet-impregnation method. The obtained UIO-66-PL was a kind of stable porous liquid with well-maintained permanent porosity and liquid-like behavior at room temperature. More importantly, this UIO-66-PL has larger gas absorption capacities than its reference IL hindered solvent as the well-preserved permanent porosity could act as free void space for gas accommodation. Also, IL could serve as a selective gate for target gas to the permanent porosity within UIO-66-PL, i.e., the majority of the permanent porosity in UIO-66-PL is inaccessible to nitrogen, but available for carbon dioxide, demonstrating that this UIO-66-PL could function as a type of fluid selective gas sorbent with high target gas solubility.

Диафрагма и мембрана для щелочного электролиза воды с гидрогелем гидроксида циркония в качестве гидрофильного наполнителя

The paper presents data on a new type of separation materials for alkaline water electrolyzers: a diaphragm synthesized by the phase inversion method and a multilayer microfilm membrane with zirconium hydroxide hydrogel as a hydrophilic filler. Experimental data are presented on their porosity, electrical conductivity, gas density, as well as the results of their tests as part of an alkaline electrolyzer battery in comparison with a porous diaphragm based on polysulfone with a hydrophilic filler (TiO2), synthesized by the traditional method of phase inversion. The advantages and disadvantages of new materials are determined, the ways of further research and development are determined.

Hydrophilic fillers for anione exchange membranes of alkaline water electrolyzers

Alkaline water electrolysers are widespread in many industries, including systems with hydrogen cycle of energy storage. One of the problems of modern alkaline water electrolysers is insufficient purity of generated electrolysis gases relative to electrolysis systems with solid-polymer electrolyte. In this regard, work on modification of existing porous diaphragms is actively carried out. One new area of research is the impregnation of new hydrophilic fillers into the composition of existing diaphragms and the transition to ion-solvate membranes. In this work the synthesis of zirconium hydroxide hydrogel inside a porous diaphragm with the hydrophilic filler TiO2 was carried out. This synthesis makes it possible to obtain a membrane with anion-exchange properties. A possible mechanism of OH- hydroxyl ion transfer by immobilized K+ ion was also proposed. The obtained results demonstrated the resistance of the membrane to concentrated alkaline solutions.

Highly sulfonated chitosan-polyethersulfone mixed matrix membrane as an effective catalytic reactor for esterification of acetic acid

A new mixed matrix membrane (MMM) incorporating sulfonated polyethersulfone (SPES) and sulfonated crosslinked chitosan (SCCS) as a superior hydrophilic filler was synthesized and applied as a catalytic pervaporation membrane reactor (PMR) for the esterification of acetic acid with ethanol. The optimal conditions for esterification over SPES-SCCS were preliminarily studied using a batch reactor (BR). The synthesis of ethyl acetate was studied in the PMR based on experimental findings of BR esterification. The pervaporative separation of water in the PMR gave it better catalytic performance than the BR. More importantly, the newly developed PMR is permselective towards the ethyl acetate product.

TECHNOLOGICAL ASPECTS OF OBTAINING AMINOALDEHYDE OLIGOMER MODIFIED WITH CROTONALDEHYDE

Today, there is a growing demand for oligomers containing amino groups in the world, including in woodworking, textile, plastics, as well as in many other industries, such as the fur industry.In our republic, the work aimed at the purposeful use of waste from cocoon processing plants is developing rapidly.The resulting oligomers are used as fillers in the leather-fur industry. Because today, obtaining hydrophilic fillers using local raw materials is one of the urgent problems of science. Taking this into account, in this article oligomers based on croton aldehyde and diethanolamine were obtained from cocoon waste and the extraction technology was explained. Mechanisms of synthesis of oligomers are presented.The sequence and schemes of technological processes are presented. KEYWORDS:croton aldehyde, diethanolamine (DEA), sericin, cerine, amino acid, condensation, vacuum chamber, modification, aminoaldehyde

Preparation and modification of monodisperse large particle size crosslinked polystyrene microspheres and their application in high performance liquid chromatography

The traditional seed preparation method of polystyrene was improved. Firstly, low molecular weight polystyrene seed microspheres with molecular weight of about 10,000 were successfully prepared by adding copolymer inhibitor and adjusting initiator azodiisobutyronitrile. Then, the polystyrene-divinylbenzene microspheres with large particle size were successfully prepared by the method of seed swelling polymerization, using divinylbenzene as crosslinking agent. Polystyrene-divinylbenzene polymer microspheres were characterized by scanning electron microscopy and gel permeation chromatography. The results showed that the molecular weight of polystyrene seed microspheres decreased with the increase of initiator AIBN dosage. Catechol and potassium iodide could significantly reduce the molecular weight of polystyrene seed microspheres. The size of the expanded microspheres prepared from low molecular weight seeds was controllable (up to 10 μm), with uniform particle size distribution and good monodispersity. Large size polystyrene-divinylbenzene microspheres can be used as stationary phase filler for reversed-phase chromatography, and have a good effect in the purification of industrial phytol. Sulfonated-polystyrene-divinylbenzene can be used as hydrophilic chromatographic filler to separate inosine and uridine. In addition, the baseline separation of cytosine, uracil and thymine was successfully achieved by sulfonated-polystyrene-divinylbenzene column in sodium phosphate buffer/acetonitrile mobile phase.