The current research provides the potential role of active nonlinear control functions in the asymptotic convergence of the synchronized errors in a comprehensive manner. Firstly, we design a systematic procedure to investigate hybrid synchronization in identical chaotic chemical reactor systems via active control method (ACM). In view of master-slave configuration and Lyapunov’s theory of stability, the considered methodology determines the global asymptotic stability of the error dynamics of the given system. Finally, numerical simulations using MATLAB toolbox are implemented for illustrating the efficacy and feasibility of the discussed strategy.