Electric powertrains have different characteristics than conventional powertrains with combustion engines and require unconventional aircraft designs to evolve their full potential. Therefore, this paper describes a method to identify potential aircraft designs with electrified powertrains. Promising technology options in the fields of powertrain architecture, aerodynamic interactions, onboard systems and operating strategies were collected by the project partners of the LuFo project GNOSIS. The effect of the technology options on a commuter aircraft was evaluated in terms of global emissions (hbox {CO}_{2}), local emissions (text {NO}_{text {X}} and noise) and operating costs. The evaluation considers an entry into service in 2025 and 2050 and is based on the reference aircraft Beechcraft 1900D. Literature review and simplified calculations enabled the evaluation of the aerodynamic interactions, systems and operating strategies. A preliminary aircraft design tool assessed the different powertrain architectures by introducing the two parameters ’power hybridization’ and ’power split’. Afterwards, compatible technology options were compiled into technology baskets and ranked using the shortest euclidean distance to the ideal solution and the farthest euclidean distance to the worst solution (Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) method). An analysis of the CS 23 regulations leads to a high-wing design and excluded the partial turbo-electric powertrain architecture with the gas turbine in the aircraft tail. For 2025, a partial turbo-electric powertrain with two additional electric driven wingtip propellers was selected. A serial hybrid powertrain, which uses a gas turbine or fuel cell in combination with a battery, powers distributed electric propulsors at the wing leading edge in 2050. In both scenarios, the aircraft design includes an electric environmental control system, an electric driven landing gear and electro-hydraulic actuators for the primary flight control and landing gear.