IntroductionCompare and report the outcomes of the re-rupture rate of isolated ACL reconstruction using autograft hamstring and a soft tissue hybrid graft.MethodsProspective, single-center, comparative-study of subjects who underwent arthroscopic reconstruction of the ACL with autograft-hamstring or a soft tissue hybrid-graft. Patients with isolated ACL tears were included and underwent anatomic single-bundle reconstruction utilizing an independent tunnel drilling-technique and had at least 24-months follow-up. The primary outcome assessed was the presence or absence of ACL re-rupture. Secondary clinical outcomes consisted of the International Knee Documentation committee(IKDC), UCLA-ACL-QL evaluations and the Visual Analog Scale-(VAS).ResultsBetween February-2010 and April-2013 ninety-five patients between ages 18-40 were enrolled. 71 autograft hamstring and 24 soft tissue hybrid graft ACL reconstructions. Follow-up period was 24 to 32 months (mean 26.9 months). There were no statistically significant differences in patient demographics or Outerbridge classification. No statistically significant differences in ACL re-tears (4.2%, 6.15%; p=0.57) between groups. Clinical IKDC and UCLA ACL-QL improvement scores revealed no statistically significant differences in autograft and hybrid graft (41.1 ± 11.6; 42.9 ± 13.6; p=0.65), (31.8 ± 9.9; 31.5 ± 11.1; p=0.37). The mean pain level decreased from 7.9 to 3.1 in autograft group and 6.8 to 1.9 in the hybrid group (p=0.124).ConclusionThe use of a hybrid graft in a young, active population is comparable to ACL reconstruction utilizing the gold standard-autograft hamstring. Surgeons can feel confident using hybrid soft tissue grafts for planned primary ACL reconstruction or as an alternative graft in cases where insufficient size hamstring call for allograft augmentation. IntroductionCompare and report the outcomes of the re-rupture rate of isolated ACL reconstruction using autograft hamstring and a soft tissue hybrid graft. Compare and report the outcomes of the re-rupture rate of isolated ACL reconstruction using autograft hamstring and a soft tissue hybrid graft. MethodsProspective, single-center, comparative-study of subjects who underwent arthroscopic reconstruction of the ACL with autograft-hamstring or a soft tissue hybrid-graft. Patients with isolated ACL tears were included and underwent anatomic single-bundle reconstruction utilizing an independent tunnel drilling-technique and had at least 24-months follow-up. The primary outcome assessed was the presence or absence of ACL re-rupture. Secondary clinical outcomes consisted of the International Knee Documentation committee(IKDC), UCLA-ACL-QL evaluations and the Visual Analog Scale-(VAS). Prospective, single-center, comparative-study of subjects who underwent arthroscopic reconstruction of the ACL with autograft-hamstring or a soft tissue hybrid-graft. Patients with isolated ACL tears were included and underwent anatomic single-bundle reconstruction utilizing an independent tunnel drilling-technique and had at least 24-months follow-up. The primary outcome assessed was the presence or absence of ACL re-rupture. Secondary clinical outcomes consisted of the International Knee Documentation committee(IKDC), UCLA-ACL-QL evaluations and the Visual Analog Scale-(VAS). ResultsBetween February-2010 and April-2013 ninety-five patients between ages 18-40 were enrolled. 71 autograft hamstring and 24 soft tissue hybrid graft ACL reconstructions. Follow-up period was 24 to 32 months (mean 26.9 months). There were no statistically significant differences in patient demographics or Outerbridge classification. No statistically significant differences in ACL re-tears (4.2%, 6.15%; p=0.57) between groups. Clinical IKDC and UCLA ACL-QL improvement scores revealed no statistically significant differences in autograft and hybrid graft (41.1 ± 11.6; 42.9 ± 13.6; p=0.65), (31.8 ± 9.9; 31.5 ± 11.1; p=0.37). The mean pain level decreased from 7.9 to 3.1 in autograft group and 6.8 to 1.9 in the hybrid group (p=0.124). Between February-2010 and April-2013 ninety-five patients between ages 18-40 were enrolled. 71 autograft hamstring and 24 soft tissue hybrid graft ACL reconstructions. Follow-up period was 24 to 32 months (mean 26.9 months). There were no statistically significant differences in patient demographics or Outerbridge classification. No statistically significant differences in ACL re-tears (4.2%, 6.15%; p=0.57) between groups. Clinical IKDC and UCLA ACL-QL improvement scores revealed no statistically significant differences in autograft and hybrid graft (41.1 ± 11.6; 42.9 ± 13.6; p=0.65), (31.8 ± 9.9; 31.5 ± 11.1; p=0.37). The mean pain level decreased from 7.9 to 3.1 in autograft group and 6.8 to 1.9 in the hybrid group (p=0.124). ConclusionThe use of a hybrid graft in a young, active population is comparable to ACL reconstruction utilizing the gold standard-autograft hamstring. Surgeons can feel confident using hybrid soft tissue grafts for planned primary ACL reconstruction or as an alternative graft in cases where insufficient size hamstring call for allograft augmentation. The use of a hybrid graft in a young, active population is comparable to ACL reconstruction utilizing the gold standard-autograft hamstring. Surgeons can feel confident using hybrid soft tissue grafts for planned primary ACL reconstruction or as an alternative graft in cases where insufficient size hamstring call for allograft augmentation.