Pregnant women's compliance in consuming vitamin supplements is the behavior of following the instructions or rules given by health workers to prevent and improve the nutritional status of women of childbearing age, especially pregnant women. The aim of the research was to analyze the relationship between age, education, employment, parity, ANC quantity, husband's support and the role of health workers with compliance with multi-micronutrient supplement consumption among pregnant women in the Gorontalo City Health Center area. This research method uses descriptive statistical analysis research methods. With a cross sectional design, the sample size was 112 pregnant women from 7 health centers in the city of Gorontalo using proportional sampling. Data analysis technique using Binary Logistic Regression. The results of the research show that the age variable has a sig value (P-Value = 0.001 < α (0.05) with compliance with pregnant women, education sig (P-Value = 0.015 < α (0.05) with compliance with pregnant women, employment sig (P -Value = 0.009 < α (0.05) with compliance of pregnant women, parity sig (P-Value = 0.002 < α (0.05) with compliance of pregnant women, ANC quantity sig (P-Value = 0.000 < α (0, 05) with compliance with pregnant women. The conclusion is that there is a relationship between age, education, employment, parity, quantity of ANC, and compliance with multi-micronutrient supplement consumption in pregnant women.