Hungarian Population Research Articles

First Report of Porcine Parvovirus 8 in Europe: Widespread Detection and Genetic Characterization on Commercial Pig Farms in Hungary and Slovakia.

Porcine parvovirus 8 (PPV8), a novel virus in the Parvoviridae family, was first identified in 2022 in lung samples of domestic pigs from China. Retrospective analyses showed that it had been circulating in China since 1998, but no other countries had reported its presence so far. A recent study conducted in South America did not detect any PPV8-positive samples in that region. Here, we report the detection of PPV8 in Hungarian and Slovakian pig farms and the estimated prevalence of the virus in Hungary. Altogether, 2230 serum, 233 oral fluid, and 115 processing fluid samples were systematically collected from 23 Hungarian and 2 Slovakian pig farms between 2020 and 2023. A real-time quantitative PCR method was developed to detect the viral genome. Our results revealed the presence of PPV8 on 65% of the Hungarian farms and both Slovakian farms included in our study, marking its first detection in Europe. Oral fluid samples showed the highest positivity rates, reaching up to 100% in some herds. The viral genome was successfully detected in serum and processing fluid samples too, but with significantly lower prevalence rates of 4% and 5%, respectively. Genetic analysis of 11 partial VP2 sequences demonstrated high similarity to the original Chinese strain but with unique amino acid mutations, suggesting possible local evolution of the virus. Our study presents the first scientific evidence of PPV8 infection outside of China and offers a comprehensive assessment of its prevalence in the Hungarian pig population. Further research is required to understand its potential impact on swine health.

The (Im)Mobile Ethnic Hungarian Minority Population in Transcarpathia, Western Ukraine

Abstract This article aims to contribute to the growing international literature on (im)mobility. Drawing on the aspiration/ability model introduced by Jørgen Carling and developed by Hein de Haas (aspiration/capability), it analyzes the patterns of (im)mobility in the Hungarian ethnic minority living in Transcarpathia, Western Ukraine, in the last decade. The data, deriving from qualitative fieldwork conducted regularly since 2016 in multiple municipalities in Transcarpathia, illustrates the interrelatedness of mobility and immobility in family livelihood strategies in a peripheral region. The article highlights the impact of Hungary’s kin-state policies, particularly citizenship policies, and the geographical proximity to the kin-state in the ethnic-kin minority community, which enables the mobility of certain family members while rendering others immobile. Furthermore, it demonstrates how the diversified, age and gender-specific (im)mobility strategies are applied in geopolitical turmoil.

Mary N. Taylor. Movement of the People: Hungarian Folk Dance, Populism, and Citizenship

Mary N. Taylor. <i>Movement of the People: Hungarian Folk Dance, Populism, and Citizenship</i>

Genetikai alapú személyre szabott táplálkozás és az étrend-kiegészítő fogyasztás kapcsolata a magyar lakosság körében

Genetic-based personalised nutrition is a concept that adapts diets, foods and nutrients to a person's individual needs (genetic, lifestyle and environmental), of which the use of supplements can be an integral part. Personalised nutrition, as a new technology and nutritional principle, could be a good way to improve the objective health status of the population in a meaningful way. However, previous research has shown that Hungarian consumers are distrustful and uncertain about this new technology, despite its obvious benefits. My main objective is to identify the attitudes towards nutrigenomics in relation to dietary supplement consumer behaviour. My quantitative analysis was carried out on a nationally representative sample of 1000 people. In the present study, I describe the clusters of the Hungarian population based on their dietary supplement consumption behaviour. Each cluster has different opinions on who they perceive as having an advantage in the applicability of genetic-based tests and to what extent they expect consensus among experts on genetic-based tests. Clusters show characteristic differences in openness to innovation and attitudes towards genetically personalised nutrition. I complemented my results with a qualitative study, which I conducted in the form of a netnographic survey. Through content analysis on social media, I identified the most common themes and consumer reactions to personalised nutrition on social media sites. Overall, it was found that dietary supplement consumption and the adoption of genetic-based tests show synergies in the manifestation of openness to novelty, health promotion behaviours, social norms, and positive attitudes.JEL Codes: A13, I12, P46

Vényköteles (Rx), vény nélkül kapható (OTC) gyógyszerek és étrend-kiegészítők vásárlási mintázata magyar fogyasztók körében

Over-the-Counter (OTC) medicines and food supplements plays an important role in healthcare. It is generally accepted that, when used properly, OTC medicines save consumers time and money. In this paper we looked into the purchasing behavior of the Hungarian population regarding OTC drugs and food supplements, highlighting the significance of self-medication. Using a quantitative online survey in March 2022 with a national representative sample, the research aimed to measure the out-of-pocket health expenditures, focusing on OTC drugs and food supplements. The analysis showed that the population spends more money on OTC drugs and food supplements than the co-payment of prescription (Rx) drugs, and the combined expenditures on OTC drugs and food supplements significantly contribute to the household's total healthcare costs, representing 45% of this budget. Three hypotheses were formulated to investigate the relationships between the spending on Rx medications, OTC drugs, food supplements, and various demographic factors. The analysis showed significant correlations, indicating that as expenditures on Rx medications increase, so do the purchases of OTC drugs and food supplements. Demographic analysis indicated that the younger demographic age group (18-35 years) tends to spend the least on both Rx, OTC drugs and food supplements, while the 36-50 age group exhibits the highest expenditure on food supplements. However, no significant difference in OTC drug purchases was found among those older than 36 years. The study raises further questions regarding the purchasing behavior of chronic patients, the differentiation between OTC drugs and food supplements by consumers, the influence of minors in the household on purchasing decisions, and whether the primary target demographic for these products should be expanded beyond the 35-50 aged women as it is defined nowadays.JEL Codes: I11, I12, M31

Mitochondrial Control Region Database of Hungarian Fallow Deer (Dama dama) Populations for Forensic Use.

The evidential value of an mtDNA match between biological remains and their potential donor is determined by the random match probability of the haplotype. This probability is based on the haplotype's population frequency estimate. Consequently, implementing a population study representative of the population relevant to a forensic case is vital to correctly evaluating the evidence. The emerging number of poaching cases and the limited availability of such data emphasizes the need for an improved fallow deer mtDNA population databank for forensic purposes, including targeting the entire mitochondrial control region. By sequencing a 945-base-pair-long segment of the mitochondrial control region in 138 animals from five populations in Hungary, we found four different haplotypes, including one which had not yet been described. Our results, supplemented with data already available from previous research, do not support the possibility of determining the population of origin, although some patterns of geographical separation can be distinguished. Estimates of molecular diversity indicate similarly low mtDNA diversity (Hd = 0.565 and π = 0.002) compared to data from other countries. The calculated random match probability of 0.547 shows a high probability of coincidence and, therefore, a limited capacity for exclusion. Our results indicate that despite the overall low genetic diversity of mtDNA within the Hungarian fallow deer samples, a pattern of differentiation among the regions is present, which can have relevance from a forensic point of view.

WOMEN AS THOUGHTFUL AND RESPONSIBLE CONSUMERS OF TOURISM: GENDER DIFFERENCES IN TOURISM CONSUMPTION PATTERNS AND ATTITUDES TOWARDS TOURISM

A particularly important area of research in tourism management is the study of consumer habits and attitudes towards tourism. With this in mind, an online survey was conducted in 2018 to investigate the attitudes and consumption habits of the Hungarian population towards tourism. The survey is representative of the Hungarian population aged 15–74 by gender, age groups (10-year intervals), and region of residence. Five variables were included in the analysis: gender, generations, type of municipality of residence, level of education, and subjective perception of income status. This study focuses on gender differences in. The aim of the study was to call attention to the disparate tourism consumption patterns and attitudes of females and males. Based on the statistical analysis of a representative sample of 1,085 respondents, our hypotheses about statistically verifiable differences between female and male tourism consumption behaviours were confirmed. It was found that women are more open than men to adopting environmentally responsible consumer behaviours when travelling.

Prevalence of celebrity worship: Development and application of the short version of the Celebrity Attitude Scale (CAS-7) on a large-scale representative sample.

Celebrity worship, defined as an excessive admiration towards celebrities, has generated considerable research and public interest. A widely used assessment instrument to measure celebrity worship is the 23-item Celebrity Attitude Scale. However, concerns have been raised regarding the measurement, including the inconsistent factor structure and lack of a cut-off point to identify "celebrity worshipers". The present study aims to address these concerns by testing the psychometric appropriateness of a short, 7-item version of the CAS (i.e., CAS-7) and estimating the prevalence of individuals with high-level celebrity admiration using a representative sample of Hungarian adults (between 18 and 64 years of age) according to gender, age, geographic location, and size of residence. The total sample comprised 2028 respondents, of which 769 valid responses were administered from participants who reported having a favorite celebrity (51.11% men, Mage = 36.38 years, SD = 13.36). Results indicated an excellent model fit for the two-factor and bifactor model of the CAS-7. Based on the suggested cut-off score of 26, the prevalence of high-level celebrity admiration is 4.53% in the Hungarian adult population (18-64 years of age) and 8.51% among young adults (18-34 years of age). Individuals with this high level of admiration towards a favorite celebrity reported more symptoms of problematic Internet use, depression, anxiety, and stress than individuals with general celebrity admiration levels. TheCAS-7 demonstrated sound psychometric properties, confirming its applicability in research and practice.

Genetic Polymorphisms in Exon 5 and Intron 5 and 7 of AIRE Are Associated with Rheumatoid Arthritis Risk in a Hungarian Population.

Rheumatoid arthritis (RA) is chronically persistent synovitis and systemic inflammation. Although multiple contributors are detected, only one is pivotal in the neonatal period: the negative selection of autoimmune naïve T-cells by the autoimmune regulator (AIRE) transcriptional factor. Single-nucleotide polymorphisms (SNPs) in the DNA-binding site of AIRE may determine its function and expression. We intended to analyse site-specific allelic polymorphisms in two exon (rs878081 and rs1055311) and three intron (rs1003853, rs2075876, and rs1003854) loci with an RA risk. Our analytical case-control study analysed 270 RA patients and 322 control subjects in five different genetic models using quantitative real-time PCR (qPCR) with TaqMan® assays. Statistically significant differences were found between the odds of allelic polymorphisms in the loci of rs878081, rs1003854, and rs1003853 among the controls and RA patients, and the disease activity seemed to be significantly associated with the genotypic subgroups of rs878081 and rs1055311. Our in silico analysis supported this, suggesting that allele-specific alterations in the binding affinity of transcriptional factor families might determine RA activity. Our findings highlight the involvement of neonatal self-tolerance in RA pathogenesis, providing novel insights into disease development and paving the way for an analysis of further site-specific genetic polymorphisms in AIRE to expand the intervention time for RA.

Himnuszperek a két háború közötti Csehszlovákiában Adalék a szlovákiai magyarok és a csehszlovák állam viszonyához

In the period of the First Czechoslovak Republic, Slovakia was an ethnically mixed territory, the scene of the meeting of Czechoslovak, Slovak, and Hungarian nation-building, among other things. From this point of view, the use of different national symbols, including national anthems, was a sensitive and much debated issue. This study attempts to outline the conflicts that the issue of national anthems had provoked between the state and its citizens, based on the archival records of county courts in Slovakia. The main focus of the paper is on the conflicts between the Czechoslovak state and the Hungarian population in Slovakia over the Hungarian national anthem. Based primarily on the county courts of the period and news reports in the contemporary press, the paper describes the court cases over the anthem and their outcomes. In doing so, it shows that the First Czechoslovak Republic, which was considered a liberal democracy, did not have a liberal attitude towards the use of symbols of national minorities at all.

PCR33 Study of the Effects of a 12 Week Functional Exercise Programme in the Hungarian Adult Population

PCR33 Study of the Effects of a 12 Week Functional Exercise Programme in the Hungarian Adult Population

Complete genome characterization and phylogenetic analysis of a novel polyomavirus detected in Eurasian beavers (Castor fiber)

The Eurasian beaver (Castor fiber), native to Hungary, faced local extinction in 1865 and was successfully reintroduced between mid-1980s and 2008. Despite screening programs focusing on animal health during reintroduction in other countries, information about viruses in the Hungarian beaver population remains limited. Polyomaviruses (PyVs) have been identified in various rodents, and have been detected just recently in beavers by us. In this paper we present the full genome analysis of the first PyV detected in Eurasian beaver. The novel PyV was discovered in the kidney tissues of two specimens. The genome is 5244 bp, and contains four genes. Small T-antigen (STAg) and alternative large T ORF (ALTO) genes are directly fused together forming the middle T-antigen (MTAg). VP3 is absent from the genome. Its large T-antigen (LTAg) coding sequence exhibited over 15% genetic divergence from known PyVs, supporting its classification into a new species within the genus Alphapolyomavirus, suggesting to be named Alphapolyomavirus castoris. Phylogenetic analysis, based on the LTAg gene showed, that the beaver PyV forms a distinct clade with primate PyVs within the genus Alphapolyomavirus, separate from other rodent PyVs. Phylogenetic study of the VP1 gene however showed this virus to belong in a distinct clade with the same primate PyVs, and additionally PyVs from rodents and a myocastor, which suggest host virus co-evolution. The virus detection of the euthanized beavers suggests an apathogenic persistent infections. The aquatic lifestyle of beavers may influence virus transmission, warranting further exploration of undiscovered viruses in beavers.

Population-level norm values by EQ-5D-3L in Hungary - a comparison of survey results from 2022 with those from 2000

PurposeAlthough population norms of the EQ-5D-3L instrument had been available in Hungary since 2000, their evaluation was based on a United Kingdom (UK) value set. Our objective was to estimate the population norms for EQ-5D-3L by using the new Hungarian value set available since 2020, to extend the scope to adolescents, and to compare with norms from 2000.MethodsA cross sectional EQ-5D-3L survey representative of the Hungarian population was conducted in 2022. The EQ-5D-3L dimensional responses were analyzed by age and sex and compared with the survey from 2000, by estimating population frequencies with their 95% confidence intervals; index values were evaluated by both value sets.ResultsAltogether, 11,910 respondents, aged 12 or more (578 between 12 and 17), completed the EQ-5D-3L. There was a notable improvement in reporting problems for both sexes (age 35–64) regarding the pain/discomfort and anxiety/depression compared to 2000. Below the age 44, both sexes had an EQ-5D-3L index plateau of 0.98, while above the age 55, men tended to have numerically higher index values compared to women, with the difference increasing with older age. Improvement in dimensional responses were also translated to numerically higher index values for both sexes between ages 18 and 74 compared to 2000. Multivariate regression analysis showed that higher educational attainment, lower age, larger household size, and active occupational status were associated with higher index values.ConclusionOver the past 22 years, there was a large improvement in HRQoL of the middle-aged to elderly men and women in Hungary.

Spatiotemporal distribution of Eurasian Spoonbills (Platalea leucorodia) outside the Carpathian Basin – the results of the Hungarian colour-ringing project based on twenty years (2003–2023)

Abstract The Eurasian Spoonbill (Platalea leucorodia) is a migratory waterbird. We used the confirmed observations of colour-ringed individuals (2,735 specimens) of the Hungarian population collected outside the Carpathian Basin between May 2003 and February 2023. 546 Spoonbills occurred in 28 countries. They used mainly the Central Mediterranean Flyway, however, some individuals were seen along the East Atlantic Flyway or the East Mediterranean Flyway. Three individuals were observed north of the Alps, too. A small proportion of Spoonbills crossed the Sahara and they occurred in the Sahel zone, between Sudan in the east and Senegal and Mauritania in the west. A few individuals were observed on Saharan wetlands in Algeria during winter. The most important destination for the Hungarian (Pannonian) population during the migration is Tunisia, where many of them spend the winter, primarily in the tidal area of the Gulf of Gabes. The first adults reached North Africa (Tunisia) on 28 July during their southward migration, while the last ones stayed there until 23 April. The first observation of juveniles in North Africa (Tunisia) happened on 31 August. Immature, 2- and 3-cyold birds spend the summer in unknown numbers in Tunisia. The majority of Pannonian Spoonbills migrate through the Balkans and Italy and some stay there to winter, mainly in Italy. Some of the immatures spent the summer in Italy. In southern Europe, the peak of the spring migration was in March, and the peak of the autumn migration was in September. There was also a difference in the migration of different age groups: in Southern Europe, the migration peak of adult birds falls between March and April, while most of the immatures were observed in May and June during northward migration. The peak of the southward migration in all age groups was observed in September. In the southern part of Europe, there may still be adults migrating north on 13 May, while other adults may already migrate southward on 15 May. The earliest juvenile migrating south was documented on 30 June in Italy.

The White-backed Woodpecker Dendrocopos leucotos in Hungary: results of a two-year nationwide survey

Abstract This paper summarizes a two-year (2021 and 2022) survey which sought to determine the breeding population of White-backed Woodpecker (Dendrocopos leucotos) in Hungary. The survey was initiated by the Hungarian Woodpecker Group of MME/BirdLife Hungary and was the first to be conducted nationwide on this species. All hill ranges where the species was historically known to occur were visited. A total of 31 observers were involved, and 102 UTM squares in which White-backed Woodpeckers were known to breed, or potentially breed, were visited. The results suggest that the Hungarian breeding population of this endangered species ranges between 480 and 800 pairs.

Steady-State Versus Chemotherapy-Based Stem Cell Mobilization in Multiple Myeloma: A Single-Center Study to Analyze Efficacy and Safety.

High-dose chemotherapy followed by autologous hematopoietic stem cell support is recommended in the treatment of eligible multiple myeloma (MM) patients. The aim of this study was to compare the efficacy and safety of steady-state versus chemotherapy-based stem cell mobilization in our Hungarian patient population. The subjects were 210 MM patients who underwent stem cell mobilization procedure between 2018 and 2022. Solo granulocyte colony-stimulating factor (G-CSF) was administered in 104 cases, while 106 patients received chemotherapy which was followed by G-CSF administration. We evaluated the ratio of successful mobilizations, the amount of collected stem cells, the incidence of infections and cost-effectivity in the two groups. In the steady-state group, there was a significantly higher need for plerixafor (45% vs. 13%, P < 0.001), unsuccessful stem cell mobilization was more frequent (11% vs. 3%, P = 0.024) and the mean amount of collected stem cells was lower (6.9 vs. 9.8 × 106, P < 0.001) than in the chemotherapy group. However, infections were less frequent (4% vs. 27%, P < 0.001) and the number of days spent in hospital was significantly lower (6 vs. 14 days, P < 0.001). Plerixafor was more frequently administered in those who had received lenalidomide or daratumumab than in those who had been treated with other regimens (41% vs. 23%, P = 0.007 and 78% vs. 23%, P < 0.001, respectively). Steady-state mobilization is a safe method; however, the higher rate of plerixafor administration and unsuccessful attempts may question its superiority to chemomobilization.

Genetic Characterization of Endangered Sterlet (Acipenser ruthenus, Linnaeus 1758) Gene Bank Broodstock, Natural and Cultured Populations in Hungary

The sterlet (Acipenser ruthenus) is the smallest-bodied endangered species among the six native sturgeon species of the Danube River, and self-sustaining populations still inhabit the Hungarian section of the Danube River and its largest tributary, the Tisza River. Their populations are drastically decreasing; however, they still have natural reproduction in these habitats. For the genetic conservation of the species, an ex situ gene bank is maintained in Hungary. The present study aimed to analyze the genetic resources of a gene bank with a near 40-year history and to compare it with natural populations and farmed stocks. Twelve microsatellites were used for population genetics analyses and individual genotyping of 268 specimens from two natural habitats (Danube and Tisza Rivers) and three captive stocks (a gene bank broodstock and two farms). Microsatellites revealed similar patterns among wild populations and gene bank stocks and did not show genetic differentiation (FST: 0.016–0.017) among them. These results confirmed that the gene bank broodstock properly represents the genetic background of the Danube and Tisza populations and is suitable as a source of breeding materials for the restocking programs. Negative trends were detected in the farmed stocks, reflected in reduced polymorphism at a few loci. The results of the principal component analyses indicate the farm stocks’ separation from the wild and gene bank stocks. The present genetic characterization study reveals a valuable captive stock of the endangered sterlet populations and provides unique information about the genetic similarities and differences among farms and wild stocks in Hungary. Our results provide information that contributes to preserving the genetic structure and variability in sterlet populations and supports the management of gene bank broodstock—avoiding inbreeding and preserving the unique genetic background of the Carpathian basin.

Age-friendly Transport: Traffic Safety for All

The elderly make up an increasing percentage of the European population and, with it, of the Hungarian population. Modern society is built around mobility. These two factors together lead to an increasing proportion of elderly drivers on the roads. Given the high proportion of people with chronic neurological conditions (stroke, Parkinson's disease, dementia), particular care should be taken to regularly check their fitness to drive. At present, there is no standardized, well-established protocol for the objective assessment of fitness to drive in the case of these diseases. Our paper discusses this matter.

Population normative data for OxCAP-MH capability scores.

The study aims to establish the first set of normative data for OxCAP-MH capability instrument and to examine its association with sociodemographic and anxiety/depression severity variables. A large-sample cross-sectional online survey was conducted among the Hungarian adult general population in 2021. OxCAP-MH standardized mean scores were compared across age, sex, education level, residence, employment, and marital status. Linear regression analysis was employed to determine the impact of sociodemographic and anxiety/depression severity on the OxCAP-MH score. In total, N = 2000 individuals completed the survey. The sample mean age was 47.1, with female majority (53.4%). Most respondents had completed primary education (51%), were active on labour market (52.4%), lived in larger cities (70.0%), and were married/in relationship (61.1%). Nearly half of the participants reported experiencing depression (48.5%), anxiety (44.3%), and 38.6% reported having both. The mean OxCAP-MH score for the total sample was 67.2 (SD = 14.4), the highest in the non-depressed (74.4) and non-anxious (73.6) subgroups, the lowest among those with extremely severe depression (45.0) and severe anxiety (47.7). Regression results indicated that older individuals (by β = 0.1), males (β = 2.3), those with secondary or higher education (β = 2.7 and 4.5) and students (β = 6.8) had significantly (p<0.01) higher mental capabilities. Respondents with mild, moderate, severe, or extremely severe depression (β = -6.6, -9.6, -13.8, -18.3) and those with mild, moderate, or severe anxiety (β = -4.1, -7.7, -10.3) had lower capability scores. The OxCAP-MH instrument effectively differentiated capabilities across sociodemographic groups and highlighting the impact of depression and anxiety severity on general population's mental capability.

Sociodemographic determinants of vaccination and willingness to pay for COVID-19 vaccines in Hungary, results of a cross-sectional online questionnaire

BackgroundSeveral different coronavirus disease (COVID-19) vaccines were authorized and distributed all over the world, including Hungary, but vaccination rates and acceptance of the different vaccines varied through 2021 and subsequent years. In Hungary Western vaccines and the Chinese and Russian vaccines were available in early 2021. Understanding preference and willingness to pay (WTP) for the COVID-19 vaccine could provide information for policy decision making to control the COVID-19 pandemic. We aimed to assess the socio-demographic factors influencing the COVID-19 vaccination and to analyse individual preferences for the available COVID-19 vaccines in Hungary.MethodsA cross-sectional online questionnaire survey was conducted between 25–05-2021 and 08–06-2021 exploring the vaccine acceptance and WTP for vaccination in the Hungarian general population. To assess the preferences towards the different vaccines available in Hungary at the time of the study, we used a multi-step WTP task.ResultsAltogether 2,000 respondents filled out our survey, with the average age of 49.1 (SD = 15.3), out of whom 370 respondents (18.5%) stated that they already had a COVID-19 infection. Age above 65 years, male gender, higher level of education, higher income and residence in the capital or county seats were associated with a higher probability of vaccination. The average WTP ranged from 14.2 to 30.3 EUR for the different vaccine types.ConclusionsMales, respondents with higher education and income stated a higher WTP value for all vaccines. Better socioeconomic status increased both vaccination coverage and willingness to pay for vaccines.