Human Papillomavirus Vaccine Knowledge Research Articles

Factors affecting human papillomavirus vaccine acceptance among parents of Primary 4 to 6 boys and girls in Hong Kong.

Human papillomavirus (HPV) poses a substantial but underestimated healthcare burden in Hong Kong. This study investigated factors affecting parental acceptance of HPV vaccination after the introduction of an immunisation programme for primary school girls. We assessed parental perceptions and related factors concerning HPV vaccination for both boys and girls. We conducted a cross-sectional survey between December 2021 and February 2022 among parents of Primary 4 to 6 students in Hong Kong. Our self-administered online survey collected data regarding socio-demographic characteristics, awareness and knowledge of HPV vaccination, attitudes towards HPV vaccination, and acceptance of HPV vaccination. Characteristics were compared between boys' parents and girls' parents. Factors associated with vaccine acceptance were analysed by multivariate logistic regression. We observed high awareness of HPV vaccination among boys' parents and girls' parents; however, they demonstrated relatively poor knowledge of HPV and the HPV vaccine. An alarming low HPV vaccination uptake rate was also observed. Attitudes towards the HPV vaccine were similar between parent groups. A majority of parents believed that the HPV vaccine was safe and effective in preventing infection. Parents of boys showed lower HPV vaccine acceptance. Factors associated with acceptance differed between parent groups. High awareness of HPV and HPV vaccine is predictive of vaccine acceptance. Boys' parents are less likely to accept HPV vaccination and emphasis should be placed on addressing potential HPV vaccine hesitancy in this group. Public education should also aim to raise awareness of government vaccination programme, and implementation of catch-up vaccination programme to school children beyond primary school should be considered.

The effect of digital storytelling on women's human papilloma virus awareness: Randomized controlled experimental study.

This study aims to determine the effectiveness of the digital storytelling (DS) method in increasing human papilloma virus (HPV) awareness. The study was conducted in the gynecology and obstetrics outpatient clinic of a state hospital between April and December 2023. The universe of the study consisted of women who applied to the outpatient clinic between these dates and volunteered. A total of 80 women who met the inclusion criteria were included in the study (n = 40 for each group). Data for the study were gathered using Personal Introduction Form and Human Papilloma Virus Knowledge Scale. Repeated measures ANOVA method was used to determine the difference between the pre-training, post-first training and post-second training measurement scores according to the intervention and control groups. For significant ANOVA results, measurements with differences were compared pairwise using Bonferroni correction. All statistical analyses were examined at the p < 0.05 significance level. Socio-demographic characteristics and HPV awareness levels of women in the intervention and control groups were similar before training (p > 0.05). After the activity conducted with the digital story method in the intervention group, the HPV awareness levels of women in this group increased significantly (p < 0.05). Considering the development in each group, an increase in posttest scores is observed in both groups. However, when the increase amounts in each group in the intervention and control groups were examined, it was determined that all awareness levels increased more in the intervention group. In the intergroup comparison, it was determined that the mean measurements of general HPV knowledge, general HPV vaccine knowledge, and knowledge of the current HPV vaccination program of women in the intervention group at the first and second follow-ups after the training were higher than those in the control group. The DS method was effective in raising HPV awareness given to the intervention group. Health professionals and researchers can benefit from DS in providing health education and consultancy services such as HPV awareness.

Awareness and knowledge of human papillomavirus, vaccine acceptability and cervical cancer among college students in Saudi Arabia

ABSTRACT Human papillomavirus (HPV) is the most prevalent sexually transmitted infection among teenagers and young adults. HPV vaccination and screening are vital preventive measures to reduce the incidence of HPV-related complications, including cervical cancer. Given the rising global incidence of cervical cancer, understanding the factors influencing awareness and knowledge among young adults in Saudi Arabia is essential for developing effective prevention strategies. This study investigates the levels of awareness, knowledge, and vaccine acceptability regarding HPV and cervical cancer among college students in Saudi Arabia. A cross-sectional study was conducted between May and September 2023 among 442 students in Saudi Arabia using a structured questionnaire to assess their knowledge and awareness of HPV, HPV vaccination, and cervical cancer. Multivariate logistic regression analysis was employed to examine the associations between predictor and dependent variables. Among participants, 54.1% were aware of HPV, and 66.5% had heard of cervical cancer. However, only 17% correctly identified HPV16 and HPV18 as high-risk genotypes for cervical cancer. Awareness of the HPV vaccine was reported by 36.2% of participants, with just 10% having received the vaccine. Female students exhibited significantly higher knowledge levels than males (p = .018). The primary barrier to vaccination was identified as a lack of education and awareness (80.1%). The study highlights a significant gap in knowledge and awareness regarding HPV, its vaccine, and cervical cancer among college students in Saudi Arabia. Targeted educational programs and awareness campaigns are essential to enhance understanding and promote preventive practices, including vaccination and regular screening.

Knowledge and acceptability of the human papillomavirus vaccine and associated factors among adolescent girls in public primary schools in Dessie Town, South Wollo, Northeast Ethiopia, 2020: A cross-sectional study.

To assess the knowledge and acceptability of the human papillomavirus (HPV) vaccine and the associated factors among adolescent girls in public primary schools in Dessie Town, South Wollo, Northeast Ethiopia in 2020. This was an institutional cross-sectional study conducted from 1 November to 30 November 2020 among 844 adolescent girls. A systematic random sampling method was used to select participants, who completed a pretested, self-administered questionnaire. Data were entered into EpiData V.4.6 and exported to SPSS V.25 for analysis. A binary logistic regression model identified the contributing factors to HPV vaccine knowledge and acceptance. Adjusted OR (AOR) and 95% CI computed at p<0.05 were used to assess significance levels. The primary outcomes of interest were knowledge and acceptability of the HPV vaccine. The HPV vaccine is known and acceptable to 47% and approximately 43% of the respondents, respectively. Age (AOR=3.51, 95% CI 1.62 to 7.6), father's educational level (AOR=2.62, 95% CI 1.57 to 4.38) and parent-child communication about sex and reproductive health (AOR=1.94, 95% CI 1.36 to 2.76) were associated with knowledge of the HPV vaccine. Acceptance of the HPV vaccine was significantly influenced by fathers' educational level (AOR=1.88, 95% CI:1.02 to 3.29), knowledge of Pap smear tests (AOR=2.54, 95% CI 1.79 to 3.62) and knowledge of the HPV vaccine (AOR=5.30, 95% CI 3.77 to 7.73). In this study, there was generally good and high acceptance of the HPV vaccine, respectively, compared with a study conducted in Southwest Ethiopia. The study, however, had limitations in terms of recall bias, assessment of coverage/effectiveness over time and generalisability due to the institutional sample used.

Abstract A109: Knowledge of HPV vaccination and HPV-associated cancers among Arab- Americans

Abstract Background: Human papillomavirus (HPV) includes oncogenic subtypes linked to the majority of head and neck and genitourinary cancer cases. Despite suggestions to boost HPV vaccine uptake by increasing HPV awareness, public understanding remains suboptimal. This is especially noted among cultural and ethnic minorities, with limited literature addressing this gap. This study evaluated awareness of HPV and HPV-associated cancers among Arab Americans. Methods: This was a cross-sectional study conducted between March and July 2023. Surveys were provided in both English and Arabic based on participants' preferences. Recruitment took place at various venues such as fairs, functions, and religious and cultural gatherings, targeting self-identifying Arab Americans residing in Michigan. Dependent variables included participants' awareness (yes/no/don’t know) of HPV, HPV vaccine, and HPV association with specific cancers (cervical, penile, anal, vulvar, vaginal, and oropharyngeal). Independent variables included age, gender, level of education, frequency of doctor and dentist visits in the past year, number of oral and vaginal sexual partners, and cigarette use. Descriptive statistics were used to analyze survey responses. Multivariable logistic regression models estimated the associations between HPV awareness and sociodemographic factors. Results: A total of 289 individuals were included in the study, of whom almost half (47%) were not aware of HPV and the HPV vaccine. Awareness of HPV association with specific cancers were as follows: 50.5% for cervical cancer, 48.4% for vaginal cancer, 42.4% for vulvar cancer, 41.5% for penile cancer, 38.9% for anal cancer, and 37.9% for mouth/throat cancer. In multivariable logistic regression models, compared to females, males were less likely to be aware of HPV vaccine (OR 0.37, 95% CI 0.19 – 0.72); or of HPV association to cervical (OR 0.38, 95% CI 0.19-0.73) and anal (OR 0.49, 95% CI 0.26-0.94) cancers. Similarly, respondents who had lower education were less likely to be aware that HPV could cause cervical (OR 0.31, 95% CI 0.14-0.69), anal (OR 0.30, 95% CI 0.13-0.69), as well as mouth/throat (OR 0.34, 95% CI 0.14-0.80) cancers compared to those with college degrees. Conclusions: Awareness of HPV, the vaccine and related cancers among Arab Americans are suboptimal. Being female or having a college education correlates with greater awareness of HPV and HPV-associated cancers. This underscores the necessity for targeted interventions to improve awareness among this population. Future interventions should focus on increasing knowledge of how HPV can cause several cancers and how those cancers could be prevented through HPV vaccination. Citation Format: Eric Adjei Boakye, Nada Al-Antary, Reem F Siddiqui, Marissa Gilbert, Lamis Fakhoury, Mrudula Nair, Milkie Vu, Farzan Siddiqui. Knowledge of HPV vaccination and HPV-associated cancers among Arab- Americans [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A109.

Abstract A116: Cervical cancer awareness, knowledge, and attitudes in young adult students on a Northern California college campus

Abstract Cervical cancer is the fourth most common gynecological malignancy in women worldwide. Human papillomavirus (HPV) is the primary cause of cervical cancer, with increased risk associated with select serotypes HPV 16 and 18. This study assesses cervical cancer awareness, knowledge of HPV, and attitudes towards vaccination among a convenience sample of San Francisco State University (SFSU) students. Despite the availability of effective HPV vaccines and associated cervical cancer prevention, vaccine uptake remains relatively low which may be due to various factors, including lack of awareness and vaccine knowledge. A convenience sample survey assessing cervical cancer awareness, behaviors and attitudes about HPV vaccine was administered to students on the San Francisco State University campus. The data was collected anonymously, via QR code. Participants received a $10 Target gift card. At completion of the survey, a 5x7 information card about Cervical Cancer and HPV vaccines, developed by and for college students, was distributed to participants. A total of 100 students completed the survey. Participants average age was 23-24 years old; 60% of participants identified as female; 34% as male. The vast majority of participants were aware of cervical cancer. Among 60 female respondents, 25 (42%) reported having had a pap smear, but a larger proportion had not. Of the female participants over age 21 years old, 12 out of 62 had never had a pap smear. 39% of respondents were not aware of the HPV vaccine and its relationship to cervical cancer prevention. There was a large difference in HPV vaccine awareness by gender and age. Of the 60 female respondents, 20 had reported being unaware of the HPV vaccine, while 17 of the 34 male respondents also reported being unaware. At completion of the survey, two-thirds of respondents reported a plan to receive a pap smear as recommended. 16% said they will not, and 21% were unsure. Our survey set out to understand the distribution of knowledge, awareness, attitudes and behaviors about cervical cancer and HPV vaccination on the SF State college campus. We found that most students on our campus are aware of cervical cancer. However, a small proportion of participants eligible for pap smears have yet to undergo the procedure. Our research also revealed that there is a lack of understanding regarding the importance of HPV vaccination, with significant differences in awareness by gender and age. This study underscores the need for targeted educational initiatives on cervical cancer awareness, knowledge, and attitudes towards HPV and its vaccine. To improve awareness and preventive actions, we can; increase the efforts to educate the public about the importance of HPV vaccinations and regular Pap smears and improve access to vaccination and screening services. Addressing gaps in knowledge and negative impressions of HPV vaccine can lead to the ultimate eradication of CC as we know it. Citation Format: Elissa I. Sanders, Kim F. Rhoads, Suzana Beyene. Cervical cancer awareness, knowledge, and attitudes in young adult students on a Northern California college campus [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A116.

Pediatric Oncology Providers' HPV Vaccine Knowledge, Attitude, Self-Efficacy, and Practice after Communication Training: A Comparison with a National Survey.

Human papillomavirus (HPV) vaccinations prevent HPV infection and related cancers. Despite being at higher risk of secondary cancers linked to HPV, childhood cancer survivors (CCS) are undervaccinated. This study aimed to compare pediatric oncology providers' knowledge, attitudes, self-efficacy, and practices regarding HPV vaccination among those who participated in a multilevel educational HPV vaccine program with those of a national sample of oncology providers. Between February and March 2023, 39 providers from five pediatric oncology clinics in Texas completed online surveys, assessing knowledge about CCS risk for HPV-related cancers, attitudes towards the HPV vaccine, and confidence in recommending the vaccine to CCS. The results were compared with a national survey of providers conducted in 2019 (n = 195). The findings showed that providers who participated in our program had greater knowledge of CCS increased risk for HPV-related cancers (96% vs. 38%; p < 0.001); greater confidence in discussing and recommending the HPV vaccine (100% vs. 66%, p < 0.001) and addressing parental concerns (100% vs. 69%, p < 0.001); and a more positive attitude about oncology providers than general pediatricians, recommending (96% vs. 71%; p = 0.006) and administering the HPV vaccine to CCS (96% vs. 53%, p < 0.001). This study underscores the importance of educating oncology providers about the increased risk of CCS and improving their self-efficacy to recommend the HPV vaccine, promoting vaccination in the oncology setting.

Impact of a health education session on the knowledge of Human Papillomavirus Vaccination (HPV) among the school teachers

Introduction: Cervical cancer is the second most common cancer in women worldwide and the most common cancer cause of death in developing countries. Human Papilloma Virus (HPV) vaccine is crucial in reducing its incidence. Unfortunately, there is limited awareness about the availability of the HPV vaccine in India. Method: Knowledge about HPV was assessed among the school teachers by using a questionnaire about HPV and HPV vaccine. Following a health education session on HPV and its vaccination using a PowerPoint presentation, their knowledge was reassessed. Results: A total of 155 teachers participated in the research (152 female, 3 male) from 5 schools. A significant negative association (r = -0.186) (p&lt;0.05) between the age and pre-test score of the participants was noted. The mean of pre intervention score (7.03 ± 3.35) was less than the mean of post intervention score (12.64 ± 2.41). Paired t-Test was performed and the difference was found to be statistically highly significant (p&lt;0.01). Conclusion: The pre-test results revealed a clear gap in knowledge about the HPV vaccine among school teachers. However, the substantial increase in understanding following the session highlighted the effectiveness of basic educational interventions in closing their knowledge gap regarding vaccination.

The role of personal health beliefs and altruistic beliefs in young Chinese adult men’s acceptance of the human papillomavirus vaccine

Administering the human papillomavirus (HPV) vaccine to men offers substantial health benefits for both themselves and their female partners. In mainland China, the HPV vaccine has not been approved for men, and little is known about their acceptance of it. This study aims to assess the acceptability of HPV vaccine among young Chinese adult men and examine the association between personal health beliefs, altruistic beliefs, and HPV vaccination intentions and behavioral attempts. A cross-sectional study was conducted among male university students using a multistage cluster sampling method in eight universities across five districts in Zhejiang Province, China. Data were collected from December 2020 to January 2021 using a self-administered, anonymous online questionnaire. Of the 1937 participants, 1009 who had heard of the HPV vaccine completed the questionnaire. Over one-third (40.4%, 408/1009) had high levels of HPV and HPV vaccine knowledge. A total of 695 of 1009 (68.9%) expressed an intention to receive the HPV vaccine when available, and 329 of 1009 (32.6%) had proactively inquired about male HPV vaccination. Perceived susceptibility, perceived benefits, perceived gender barriers, and perceived benefits of male HPV vaccination for female partner were associated with HPV vaccination intentions. Lower perceived vaccine barriers, greater perceived benefits, and stronger vaccination intentions were associated with higher HPV behavioral attempts. There is an emerging demand for HPV vaccinations among young adult men in mainland China. Personal health beliefs and altruistic beliefs are crucial in promoting young adult men’s acceptance of the HPV vaccine. Emphasizing both male-specific benefits and altruistic motivations may enhance HPV vaccine acceptability among young adult men.

Human Papillomavirus Vaccination Status and its Associated Factors Among Female Medical College Students in Hubei, China: A Cross-sectional Study

Background: Despite the introduction of the human papillomavirus (HPV) vaccine in China in 2016, the uptake rates of HPV vaccination were low. This study aimed to assess the status of HPV vaccination and identify associated factors influencing HPV vaccination among female medical college students in Hubei province. Methods: Using a multistage sampling method, this was a cross-sectional study conducted in six colleges in Hubei province in 2023. The data were collected by web-based online software. Multiple logistic regression was applied to explore factors associated with the uptake of the HPV vaccine. Results: Overall, 1148 female medical college students were enrolled in this study. Approximately 13.9% of participants reported receiving the HPV vaccine. About 85.5% of unvaccinated participants showed high levels of intention to receive an HPV vaccine in the future, and 89.1% of the participants had accessed information about the HPV vaccine from the Internet. Multiple logistic regression demonstrated that knowledge pertaining to HPV and the HPV vaccine, factors aligned with the protection motivation theory (PMT), and socio-variables such as the mother’s educational background and the presence of vaccinated family members were associated with the uptake of the HPV vaccine. Conclusion: Our findings revealed that the HPV vaccination was associated with the knowledge, perceived susceptibility, perceived response efficacy, and self-efficacy of HPV and the HPV vaccine among female college students. Therefore, increasing HPV and HPV vaccine knowledge within the framework of PMT may serve as an effective strategy to promote HPV vaccination rates among college students.

Knowledge of the Human Papillomavirus Vaccine and Willingness to Accept Vaccination in the Postpartum Period.

Human papillomavirus (HPV) vaccines prevent cervical cancer. The inpatient postpartum period presents a unique window for vaccination. Our study investigates HPV vaccine knowledge, barriers to vaccination, and willingness to get vaccinated during inpatient postpartum care. We conducted a cross-sectional survey of 147 participants, age 18 to 26, who delivered at our institution between November 1, 2019, and April 30, 2020. Participants completed a questionnaire that included demographics, vaccine knowledge, hesitancies, and willingness to vaccinate. We used descriptive statistics and compared groups with chi-square or Wilcoxon rank sum for categorical variables and t-test for continuous variables. Of the 147 patients, 58 (39.46%) were fully vaccinated against HPV and 89 (60.54%) of participants were unvaccinated or partially vaccinated. There was a greater proportion of African American and Asian participants among unvaccinated women (28.1% vs 20.7% and 16.9% vs 1.7%, respectively). Most unvaccinated participants (52.9%) were willing to get vaccinated in the postpartum unit. Both vaccinated and unvaccinated groups were similarly aware that the HPV vaccine prevents cervical and oropharyngeal cancers and genital warts. The top barrier to future vaccination was forgetting to complete the vaccination series. Most women were not fully vaccinated but were willing to receive their first dose while in the postpartum unit. African American women were less likely to be vaccinated and expressed more unwillingness to accept vaccination. We identified barriers to HPV vaccination that can be tackled with the initiation of inpatient postpartum vaccination.

"That Was an Eye Opener for Me": Mixed-Methods Outcomes Educating Texas Community Health Workers on HPV Vaccination Using Project ECHO®.

Human papillomavirus (HPV) is known to cause six different types of cancer. HPV vaccination can prevent over 90% of these cancers. Community health workers (CHWs) have the potential to drive HPV vaccination demand through education and navigation by addressing vaccine hesitancy and dis/misinformation and by reaching non-English speaking, vulnerable, or rural populations. Despite their possible reach, there is limited research on HPV vaccination education programs for CHWs. In 2020-2021, the American Cancer Society (ACS) HPV Cancer Free Texas (HPVCFT) Project implemented the eight-session Mission: HPVCFT Vaccination ECHO-CHW Program ten times. This manuscript details the program's implementation processes and outcomes. The program used the Project ECHO model and was offered in both English and Spanish. One hundred and forty-six Texan CHWs completed pre- and post-training surveys. The participants demonstrated significant HPV vaccination knowledge increases and desirable shifts in their foundational HPV vaccination beliefs, including the belief that the HPV vaccine is for cancer prevention. The participants also reported increased confidence in communicating about the HPV vaccine in the community. Improving knowledge, beliefs, and confidence in HPV vaccination is the first step in addressing concerns and increasing uptake. Future research and interventions are needed to better understand how CHWs can be more systematically linked to vaccination opportunities or provided with clearer paths for directing patients to providers that vaccinate.

Perception and Acceptance of Human Papilloma Virus Vaccine by Mothers in Owerri, Nigeria: A Cross Sectional Study

Introduction: Human papillomavirus (HPV) vaccination among female children 9-14 years is critical to reducing the burden of HPV-related cancers in Nigeria. We assessed caregivers’ perception and acceptance of HPV vaccination for their wards; using a structured, pretested, self-administered questionnaire in a face-to-face interview among caregivers attending a well-child/immunization clinic in Owerri, Nigeria. Methodology: Participants were recruited by convenience sampling method between August and October 2023.We analysed the cross-sectional data from 267 caregivers of caregivers aged 20–57years in a Nigerian Teaching hospital. Statistical analysis included descriptive statistics and bivariate analysis to investigate the factors associated with HPV vaccination uptake. Among the respondents, 132 (49.4%) of them had heard about HPV, and 52 (19.5%) stated that it could prevent cervical cancer. Bivariate analysis, demonstrated that tertiary education in the mother (OR 2.25, 95%CI 1.27 to 4.02) and father (OR 2.25, 95%CI 1.28 to 3.85) were significantly associated with their knowledge of HPV vaccine and their wards’ probability of taking the HPV vaccine. Participants’ intention to give HPV vaccination to their children was 77.5%. Our findings suggest that interventions tailored to enhance education and support of caregivers would significantly increase HPV vaccination among females in Nigeria. Conclusion: Being well-educated appears to guarantee good knowledge of the HPV vaccine, but not HPV prevention of cervical cancer role. Our respondents’ intention to have the HPV vaccine administered to their children was high. Concerted efforts need to be made by government and health workers to create awareness about HPV infection, HPV vaccine amongst caregivers to enhance HPV vaccine uptake.

Review of the Knowledge, Barriers, and Facilitators of HPV Vaccination among Latino Migrant and Seasonal Farmworkers in the United States.

One subgroup of Latinos whose healthcare needs must be more thoroughly addressed is the roughly three million farmworkers pursuing seasonal agricultural work within the United States (U.S.). Latino migrant and seasonal farmworkers (MSFW) face compounded political, social, and personal contexts that complicate healthcare access. Although the human papillomavirus (HPV) vaccine prevents HPV infections and cancers, uptake among Hispanic adolescents remains suboptimal. Therefore, it is important to understand Latino MSFW's HPV knowledge, as well as barriers to and facilitators of vaccination so culturally appropriate measures can bolster vaccination. An integrative review was conducted in PubMed, Scopus, and Web of Science using key search terms. Results were evaluated for compatibility with inclusion/exclusion criteria, and selected articles were coded and evaluated via thematic analysis. Six studies of various designs were ultimately included in the review. While some Latino MSFW have baseline knowledge about HPV and the vaccine, knowledge gaps remain. Participants expressed curiosity about how the vaccine works, contents, side effects, dosing, recommended age, and information about prevented diseases. Although additional education and MSFW's receptiveness to provider's recommendations were cited as major facilitators, many barriers also need addressed. Providers must leverage MSFW's existing knowledge, provide education, and facilitate vaccination to protect farmworker families from HPV and related cancers. It must become standard practice for providers to recommend the HPV vaccine to MSFW, who are receptive to this conversation. Increasing vaccination can decrease the disproportionate burden of HPV-related cancers on patients and facilitate access to healthcare services.

Improving HPV Vaccination Uptake Among Adolescents in Low Resource Settings: Sociocultural and Socioeconomic Barriers and Facilitators.

Lower- and middle-income countries (LMICs) are disproportionately impacted by human papillomavirus (HPV) and would benefit from implementing the HPV vaccine. In the context of competing health priorities, utilizing scarce domestic infrastructure and human resources for HPV vaccination remains challenging for many LMICs. Given the high benefits of the HPV vaccine, the World Health Organization (WHO) is now encouraging for all countries, particularly LMICs, to introduce HPV vaccines into their routine immunization programs. Understanding the barriers and facilitators to HPV adolescent vaccine programs in LMICs may help strengthen how LMICs implement HPV vaccine programs, in turn, increasing HPV vaccine acceptance, uptake, and coverage. To identify and assess barriers and facilitators to implementing adolescent HPV vaccination programs in LMICs. This study comprised a review of literature assessing adolescent HPV vaccination in LMICs published after 2020 from a sociocultural perspective. Overall, the findings showed that LMICs should prioritize increasing HPV vaccine availability and HPV vaccine knowledge, particularly focusing on cancer prevention, as knowledge reduces misinformation and increases vaccine acceptance. Evidence suggests that factors promoting HPV vaccine uptake include fostering low vaccine hesitancy, integrating HPV vaccination as a primary school routine vaccination, and vaccinating both genders. A one-dose HPV vaccine may enable many LMICs to increase vaccine acceptance, uptake, and coverage while controlling financial, infrastructure, and human resource costs. As HPV is one of the leading causes of death in many LMICs, implementing the HPV vaccine may be highly beneficial. Cohesive national HPV vaccine buy-in and understanding the success and challenges of prior LMIC HPV vaccine implementation is crucial to developing effective, efficient, and sustainable HPV vaccination programs.

A feasibility study assessing knowledge, vaccine hesitancy, and completion rates of free HPV vaccination in low-income uninsured adults.

Human Papillomavirus (HPV) vaccination rates remain low in the U.S., particularly among minorities and low-income, uninsured patients. We report preliminary data on a pilot study program providing education and free HPV vaccination at a clinic serving low-income uninsured adults. From October 2020 through October 2022, we assessed HPV vaccination knowledge, awareness, and prevalence of hesitancy towards receiving the vaccine among low-income uninsured patients age 18-45. The Parents Attitudes about Childhood Vaccines (PACV) survey was modified and used to evaluate vaccine hesitancy. An educational video on HPV was shown to patients declining vaccination. 43 patients were enrolled. 69.8% had heard of the HPV vaccine and 85.7% were non-hesitant based on PACV scores of 0-49. Black participants had a statistically significant higher PACV score (more hesitant) than White participants. Familiarity with the HPV vaccine correlated with lower PACV scores. Only 27% completed all three HPV vaccine doses. The availability of an education program together with free HPV vaccination are not sufficient to achieve adequate vaccination rates in low-income, uninsured adults. Innovative, culturally sensitive education and supportive interventions, in addition to access to free HPV vaccination, are warranted in order to improve vaccination rates in this underserved population.

Impact of Educational Intervention on Cervical Cancer and HPV Vaccine Knowledge, Attitudes, and Acceptance among First-Year Medical Students of Birat Medical College

Introduction: Cervical cancer poses a significant health burden, particularly in developing nations, with notable incidence and mortality rates. However, there exists a notable gap in understanding the knowledge, attitudes, and acceptance surrounding cervical cancer and the Human Papillomavirus (HPV) Vaccine. This study aims to evaluate the current awareness, attitudes, and acceptance levels of HPV Vaccine among first-year medical students, alongside assessing the effectiveness of an educational intervention on these aspects. Objectives: To evaluate current knowledge, attitude and acceptance of cervical cancer and HPV Vaccine and evaluate the impact of educational intervention. Methodology: 2 An analytical cross-sectional study was conducted among 96 first-year medical students at a medical college in Nepal from December 24, 2023, to February 28, 2024, after receiving Ethical Approval. Total enumeration sampling technique was applied, and a structured self- administered questionnaire, validated for data collection, was employed. Data were collected at baseline and after an educational intervention class to assess the impact on the knowledge, attitude, and acceptance toward cervical cancer and the HPV Vaccine. Result: Pre-intervention scores (mean=5.90, SD=1.73) significantly increased after the intervention (mean=11.65, SD=1.44) with p&lt;0.001, indicating a 97.46% increase. Willingness to receive HPV vaccination increased from 47.9% to 88.5%, and willingness to recommend vaccination increased from 88.54% to 96.88%. No significant differences were found in vaccination willingness. Conclusion: Educational interventions significantly enhanced medical students' willingness to receive and recommend HPV vaccination, suggesting potential for future healthcare provider influence on vaccination behaviors.

Assessing the Knowledge of HPV-Associated Oropharyngeal Squamous Cell Carcinoma, HPV Vaccination, and Practice Scope among Saudi Dental Students in the Western Region.

(1) Background: Human papillomavirus (HPV) infection is significantly associated with oropharyngeal squamous cell carcinoma (HPV-OPSCC), which is one of the fastest-growing cancer incidences globally. Dental practitioners play a crucial role in the primary and secondary prevention of HPV-OPSCC. There is little known about dental students' awareness regarding HPV-OPSCC and HPV vaccination, as well as their intention to promote 'primordial prevention' among their patients. HPV vaccine, and the extent of their professional responsibilities. (2) Methods: This cross-sectional study was conducted in the western region of Saudi Arabia and involved undergraduate dental students (n = 688) from six public and private dental schools. Participants were requested to complete a sequential-section anonymous online survey, with 257 successfully completing all sections of the questionnaire. The association between participant characteristics and HPV-OPSCC, HPV vaccination awareness ratings, and perceived engagement in prevention were analyzed using ANOVA and chi-squared testing. A binary logistic regression analysis was conducted to examine the variables linked to these outcomes. (3) Results: Generally, the overall level of awareness of HPV-OPSCC and HPV vaccination was acceptable, with an average score of 53.44 ± 29.3 out of 100. However, a significant knowledge gap was observed, with 53% of respondents being unaware of the common sites for HPV-OPSCC and 63.8% being uninformed of the appropriate age for HPV vaccination. Females and those with a prior history of sexually transmitted diseases (STDs) had considerably higher levels of HPV vaccination knowledge (p < 0.05). The participants showed a favorable attitude towards their responsibility of informing patients about HPV-OPSCC and advocating HPV immunization. (4) Conclusions: This study underscores the need to enhance dental students' understanding of HPV-OPSCC and HPV immunization, enabling them to effectively engage in primary and secondary preventative efforts against HPV-OPSCC.

A Cross-sectional Sectional Study to Assess Knowledge, Attitude and Practice towards Cervical Cancer, Human Papilloma Virus (HPV) Infection and HPV Vaccine among 9th to 12th Grade School Girls in Indore

Background: Human Papilloma Virus (HPV) is most common viral infection among women between 15 to 44 age group. When administered before girls or women are exposed to the virus, HPV vaccine can prevent majority of cervical cancer occurrences. Therefore to evaluate knowledge, attitudes and practices regarding cervical cancer,HPV infection and HPV vaccine among girls in grades 9 to 12 the current study was conducted.Materials and Methods: A cross-sectional study conducted between July-December 2022 in Indore governmentschools. Total 120 girls in grades 9 to 12 after receiving informed consent involved in the study. Data regarding knowledge, attitude and practice about cervical cancer, HPV infection and HPV vaccination collected using pretested semi-structured questionnaire. SPSS version 25.0 (Trial version) was used for data analysis.Conclusion: Among 120 students (34.16%) and (20.83%) had heard about cervical cancer and HPV vaccinerespectively, where majority were from class 11th and 12th. The association was significant between knowledge of students and their grades (p&lt;0.05). (3.33%) received HPV vaccine. Among unvaccinated, (68.96%) were willing to take vaccine. Hence the study found that knowledge and uptake of HPV vaccination among school girls is poor. The government needs to strengthen the various aspects of HPV education supplied in schools and HPV vaccination awareness campaigns.

Knowledge and Attitude of Mothers towards Human Papilloma Virus Vaccine Uptake in Nigeria

Background: The human papilloma virus (HPV), a principal factor in the development of cervical cancer, is identified as one of the most widespread sexually transmitted infections, leading to a variety of conditions globally, from warts to cancer. It is estimated that 75% of people worldwide will contract an HPV infection at some point in their lives. Vaccination against HPV serves as an important preventive measure to reduce the rates of cervical cancer. Objective: This study assessed knowledge, attitude of mothers toward HPV vaccine uptake in Local communities in Edo State Nigeria. Methods: A cross-sectional study utilizing a descriptive approach was carried out with 350 participants, chosen through simple random sampling. Information was gathered via questionnaires conducted by researchers and was processed with the Statistical Package for the Social Sciences (SPSS), version 25. To examine the relationships between variables, the Fisher's exact test was employed, with statistical significance determined by a P-value &lt; 0.05. Results: The average age of those surveyed was 40.4 years, with a standard deviation of 10.1 years. A mere 28.3% (44 respondents) had adequate knowledge about HPV and its vaccine. A significant portion (80%) exhibited a negative attitude toward receiving the HPV vaccine. There was a noticeable statistical correlation between the respondents' age and their awareness of HPV (with a p-value of 0.019) as well as between their employment status and their knowledge about HPV (p-value = 0.002). The primary reason cited by participants for not getting the HPV vaccine was its lack of availability. Conclusion: Knowledge and uptake of HPV vaccination among the respondents were poor. Majority also had negative attitude towards uptake of the vaccine.