Human Health Endpoints Research Articles

RIFM fragrance ingredient safety assessment, 4-heptenal diethyl acetal, CAS Registry Number 18492-65-4

• 4-Heptenal diethyl acetal; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, guaiacol, CAS Registry Number 90-05-1

• Guaiacol; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

Update to RIFM fragrance ingredient safety assessment, oxacyclotridecan-2-one, CAS Registry Number 947-05-7

• Oxacyclotridecan-2-one; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, 12-oxahexadecanolide, CAS Registry Number 6707-60-4

• 12-Oxahexadecanolide; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, phenylpropionaldehyde dimethyl acetal, CAS Registry Number 90-87-9

• 2-Phenylpropionaldehyde dimethyl acetal; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, 4-(methylthio)-4-methyl-2-pentanone, CAS Registry Number 23550-40-5

• 4-(Methylthio)-4-methyl-2-pentanone; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, 3 and 4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde, CAS registry number 31906-04-4

• 3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, benzyl phenylacetate, CAS Registry Number 102-16-9

• Benzyl phenylacetate; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, benzoic acid, CAS Registry Number 65-85-0

• Benzoic acid; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-5

• Styrene; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

Update to RIFM fragrance ingredient safety assessment, α,2,2,3-tetramethylcyclopent-3-ene-1-butyraldehyde, CAS Registry Number 65114-03-6

• α,2,2,3-Tetramethylcyclopent-3-ene-1-butyraldehyde; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, 10-undecenal, CAS Registry Number 112-45-8

• 10-Undecenal; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, methoxycitronellal, CAS Registry Number 3613-30-7

• Methoxycitronellal; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, p-methoxybenzaldehyde, CAS Registry Number 123-11-5

• p -Methoxybenzaldehyde; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, p-mentha-1,8-dien-7-yl acetate, CAS Registry Number 15111-96-3

• p -Mentha-1,8-dien-7-yl acetate; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-3

• Phenethyl propionate; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

Update to RIFM fragrance ingredient safety assessment, 1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-one, CAS Registry Number 74499-60-8

• 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-one; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

Update to RIFM fragrance ingredient safety assessment, phenylacetaldehyde diethyl acetal, CAS Registry Number 6314-97-2

• Phenylacetaldehyde diethyl acetal; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

Update to RIFM fragrance ingredient safety assessment, hexyl isovalerate, CAS Registry Number 10032-13-0

• Hexyl isovalerate; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

RIFM fragrance ingredient safety assessment, tetrahydromyrcenol, CAS Registry Number 18479-57-7

• Tetrahydromyrcenol; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.