Human Hazard Research Articles

Magnetic heterogenization of supramolecular carbohydrates for the efficient adsorption of heavy metals removal from wastewater

BackgroundAs the high impact of heavy metals hazards for humans and the environment, providing a suitable method to remove heavy metals is of great importance. Recently, magnetic adsorbents have been developed for their ease of separation, high absorption efficiency, and cost-effectiveness has been expanding. On the other hand, hybridism adsorbents composed of a magnetic core and an organic branch amended with different functional groups such as –OH, –NH2, −SH, and –COOH have suitable potentials for heavy metal removals. MethodsIn this, a simple procedure for the preparation of β-cyclodextrin bonded Fe3O4@SiO2 (β-CD-SiO2@Fe3O4) was reported. The morphological, structural, and thermal stability characteristics were investigated by the XRD, SEM, EDS, FT-IR, and TGA-DTA techniques. Next, the potential of β-CD-SiO2@Fe3O4 in the absorption of Cd2+ and Pb2+ ions from wastewaters was investigated. The effect of various parameters such as pH, adsorbent dosage, Pb/Cd concentration, and the temperature was investigated on the absorption of Cd2+ and Pb2+ heavy metal ions. Significant findingsThe maximum adsorption was achieved when pH = 6.5, heavy metal ion concentration (250 mg/L), and adsorbent dosage (0.075 g) at room temperature was used. The adsorption process could be described by kinetic models and the pseudo-second-order model was well-matched. The maximum adsorption capacities of Pb2+ and Cd2+ were obtained at 160 and 159.33 mg/g respectively. The negative value of ΔG indicates the spontaneity of the absorption process. The negative values of ΔH and ΔS show the exothermic nature of the absorption reaction.

Mechanism of mitigating on Deoxynivalenol-induced intestinal toxicity in swine and its dietary regulation strategy1

Mycotoxins are the most widely present pollutants in both dietary provisions and livestock feed, and they pose a series of hazards for humans and animals. Deoxynivalenol (DON) is a prevalent mycotoxin that is primarily produced by Fusarium spp. and commonly found in various cereal products. Feeding swine diets contaminated with trichothecene DON can lead to major adverse effects, including reduced feed intake, diminished weight gains, and compromised immune function. Among all animal species tested, swine were the most sensitive to DON. Here we explored the disruption of gut health by DON, considering aspects such as intestinal histomorphology, epithelial barrier functions, the intestinal immune system, microflora, and short-chain fatty acid production in the intestines. Numerous additives have been documented for their potential in the detoxification of DON. These additives can alleviate the toxic effects of DON on pigs by modulating the Nrf2-Keap1, mitogen-activated protein kinases (MAPKs) and Nuclear factor kappa-B (NF-κB) signaling pathways. Additionally, there are additives capable of mitigating the toxicity of DON through adsorption or biotransformation. This update has novel potential for advancing our comprehension of the mechanisms linked to DON intestinal toxicity and facilitating the formulation of innovative strategies to mitigate the impact of DON.

Combining Nontargeted Analysis with Computer-Based Hazard Comparison Approaches to Support Prioritization of Unregulated Organic Contaminants in Biosolids.

Biosolids are a byproduct of wastewater treatment that can be beneficially applied to agricultural land as a fertilizer. While U.S. regulations limit metals and pathogens in biosolids intended for land applications, no organic contaminants are currently regulated. Novel techniques can aid in detection, evaluation, and prioritization of biosolid-associated organic contaminants (BOCs). For example, nontargeted analysis (NTA) can detect a broad range of chemicals, producing data sets representing thousands of measured analytes that can be combined with computational toxicological tools to support human and ecological hazard assessment and prioritization. We combined NTA with a computer-based tool from the U.S. EPA, the Cheminformatics Hazard Comparison Module (HCM), to identify and prioritize BOCs present in U.S. and Canadian biosolids (n = 16). Four-hundred fifty-one features were detected in at least 80% of samples, with identities of 92 compounds confirmed or assigned probable structures. These compounds were primarily categorized as endogenous compounds, pharmaceuticals, industrial chemicals, and fragrances. Examples of top prioritized compounds were p-cresol and chlorophene, based on human health end points, and fludioxonil and triclocarban, based on ecological health end points. Combining NTA results with hazard comparison data allowed us to prioritize compounds to be included in future studies of the environmental fate and transport of BOCs.

Marine Pollution and Waste Management

Water covers more than 70% of the surface of the globe. The ocean, which is amazing and significantly controls the world's climate, also has a hidden crisis, namely marine pollution. In the modern world, marine pollution is becoming a bigger issue. Article 1 (1) (4) of UNCLOS : says that “Pollution of the marine environment” means the introduction by man, directly or indirectly, of substances or energy into the marine environment, including estuaries, which results or is likely to result in such deleterious effects as harm to living resources and marine life, hazards to human health, a hindrance to marine activities, including fishing and other legitimate uses of the sea, impairment of quality for use of seawater and reduction of amenities”. Chemicals and garbage, most of which originate on land and are blown or carried into the water, are the two main components of marine pollution. Marine pollution, caused by human activities like improper disposal, shipping, and overfishing, harms ecology, health, and global economic institutions. Solutions include international agreements, sustainable fishing, improved waste disposal, and raising awareness. Education-based campaigns have the power to inspire citizens, groups, and governments to action. The legislative reforms and sustainable practices are significantly aided by environmental organizations and advocacy groups. The government has made several notable efforts, such as the plastic ban, marine protected areas, clean-up programs, and environmentally friendly fishing. Several countries have enacted plastic bags, which have significantly reduced the amount of plastic pollution, while the ocean may not be affected. Creating marine protected zones helps safeguard biodiversity and gives damaged ecosystems a place to recover. This article gives a general overview of the complex issue of marine pollution and shows how important it is to have efficient waste management plans. It investigates diverse marine pollution types and causes, emphasizing the dangers it poses, such as biodiversity loss, potential health hazards for humans, and significant financial expenses.

Human papillomavirus and occupational exposure: The need for vaccine provision for healthcare providers

ABSTRACT To probe the understanding of healthcare providers regarding occupational exposure to human papillomavirus and their knowledge about human papillomavirus vaccination in relation to the American Society for Colposcopy and Cervical Pathology (ASCCP) recommendations. In this cross-sectional study, the healthcare providers at Mayo Clinic Arizona, Florida, and Minnesota were delivered an electronic survey. The survey was completed by 349 healthcare providers, with one respondent excluded for inconsistent entry. The mean age of respondents was 42.7 ± 10.9, and of those, 68% were female and 32% were male. Of the unvaccinated respondents, 43.3% were ≤ 45 y of age (eligible for vaccination), while those vaccinated formed 41% of the respondents. Healthcare providers are highly concerned about their cancer safety, as shown by their awareness of occupational human papillomavirus hazards and broad knowledge about vaccine efficacy. The use of personal protective equipment varied widely, including eyewear, double gloving, procedural face mask, N95 face mask, and/or nothing. Human papillomavirus and cancer risk was clearly perceived by healthcare providers. For professions, pairwise comparisons revealed that nurse practitioners, physician assistants, certified registered nurse anesthetists, and allied healthcare providers had lower scores than medical doctors. Despite the high level of understanding among healthcare providers of occupational human papillomavirus exposure, only a few of them knew of the recommendations of the ASCPP for vaccination of healthcare providers treating human papillomavirus-related diseases. In such cases, most of those surveyed embraced vaccination, which was considered 100% safe by medical doctors and allied health professionals.

A review on Fe2O3‐based catalysts for toluene oxidation: catalysts design and optimization with the formation of abundant oxygen vacancies

Volatile organic compounds (VOCs) are typical pollutants with hazards for humans and the environment, and can be efficiently mitigated by catalytic combustion. Fe2O3‐based catalysts are a promising choice due to their low cost and strong redox ability. Several attempts have been made to promote the catalytic performance of Fe2O3 at low temperatures. This review summarizes the research progress on Fe2O3‐based catalysts for the oxidation of toluene, one of the most common and harmful VOC. Firstly, the properties and catalytical performance for Fe2O3‐based catalysts were summarized, and the reaction mechanisms for toluene oxidation on the surface of Fe2O3 were detailed to comprehend the role of oxygen vacancy. Then, the modification for single Fe2O3 catalysts, including synthesis parameters, structure and morphology control, has been introduced to reveal the correlation between physicochemical properties of catalysts and their activity. In addition, composite Fe2O3 catalysts, which can promote catalytic performance significantly due to the synergetic effect between different components, were comprehended. Finally, waste‐derived Fe2O3 catalysts with sustainable merit as converting waste into worth have been discussed. Moreover, the advanced machine learning tools, which are helpful in accelerating catalyst design, configuration optimization and reactivity prediction, have been introduced as an emerging research opportunity for the future.

Effects of hydrogen concentration, number of obstacles, and blockage ratio on vented hydrogen-air explosions and its consequence analysis

With the swift advancement of commercial hydrogen fuel cell vehicles (HFCVs), accident risks of hydrogen explosions are heightened, especially in enclosed or semi-enclosed areas such as tunnels and underground parking lots. To prevent and control these accidents, experiments are conducted in a 1 m-long cylindrical tube at 1 atm and 286 K to study the impacts of hydrogen concentration, number of obstacles, and blockage ratios on vented hydrogen-air explosions. As the number of obstacles rises, there is a gradual rise in the maximum internal overpressure for a hydrogen concentration of 20 vol%. However, a reverse trend is observed for hydrogen concentrations of 30 vol% and 50 vol%. The size of the external flame gradually expands as the hydrogen concentration increases, but diminishes gradually with increasing in the number of obstacles and blockage ratio. The maximum external overpressure decreases as the distance to the vent increases. The maximum temperature experiences an increase with increasing in hydrogen concentration and blockage ratio but undergoes a decrease with an increase in the number of obstacles. Furthermore, the safety radii are determined using thermal radiation criteria to ensure the absence of thermal radiation hazards for humans, and PROBIT equations to ensure the absence of overpressure and impulse hazards for humans and buildings. The safety radii for humans based on thermal radiation criteria are smaller compared to those based on the corresponding overpressure and impulse hazards.

Adoption of Blockchain Technology for Data Management of Human Resource Demands in Organizational Enterprises

Human resource data accuracy has become a significant factor in assessing the effectiveness and performance of human resource management (HRM) in businesses. Numerous human resource hazards originating from asymmetric information continue to cost firms money and even put companies out of business despite the rapid progress of mobile technology and Internet technology. Blockchain is a transaction platform that makes use of the immutability qualities of immutable data records. Because of the dispersed nature of this technology, it has a broad variety of applications in numerous industries. Seeing the potential of this new technology, we picked the HRM sector since this data must be kept private and secret while still having great research value. This research presents a unique blockchain-based encryption method for establishing an HRM data method that decreases the danger of HRM data integrity. The data is authenticated using smart contracts, and data is encrypted using the proposed Improved Identity-based blowfish encryption algorithm (IIBEA) with Particle Swarm Optimization (PSO). New blocks are verified using the Proof of Work (PoW) consensus process. The suggested model's metrics are examined and compared to traditional encryption approaches. This model solves the lack of difference in the authenticity of HRM information, and it will give real and effective information to the HRM of organizational companies.

Antimicrobial, Preservative, and Hazard Assessments from Eight Chemical Classes.

Preservatives, such as isothiazolinones and formaldehyde-releasing compounds, provide safety and stability in consumer products by preventing microbial contamination. Yet these ingredients present human and environmental hazards, including allergic contact dermatitis and aquatic toxicity. The development of safer alternatives has been stymied by trade-offs between safety and efficacy. To enable the identification of safer preservatives, substances from eight functional classes were assessed for antimicrobial efficacy and human and environmental hazards. First, 130 substances were evaluated for microbial inhibitory activity against two relevant model microorganisms, Aspergillus brasiliensis (filamentous fungi) and Pseudomonas aeruginosa (Gram-negative bacteria). High-performing compounds within each class were assessed for hazards across a broad suite of human and environmental health end points. Four promising compounds were selected for further testing based on microbial inhibition, hazard profiles, and commercial availability. These ingredients were tested for biocidal activity in model home care formulations using methods adapted from industrial preservative challenge guidelines (USP-51). Two substances were identified, caprylhydroxamic acid and caprylyl glycol, that provided adequate preservation and improved toxicity profiles compared to isothiazolinone and formaldehyde-releasing preservatives. This study highlights trade-offs between antimicrobial activity and hazards across a broad spectrum of chemical classes relevant to safer preservative development.

Biological control effect of Trichoderma harzianum (Hypocreales: Hypocreaceae) against phytopathogens

AbstractChemical pesticides are synthetic substances created to manage plant pests. Frequent chemical usage causes extensive damage to crops and contributes to pest resistance, leading to environmental contamination, harm to non‐target organisms, the emergence of pesticide‐resistant species, and potential health hazards for humans. The aim of this study is to isolate, identify, and characterize biocontrol agents Trichoderma harzianum and evaluate their effects on various plant phytopathogens. T. harzianum biocontrol effects were tested against various fungal phytopathogens, including Sclerotium rolfsii, Alternaria sp., Pythium aphanidermatum, Macrophomina phaseolina, Fusarium oxysporum, Helminthosporium sativum, and Aspergillus niger. The results clearly showed that, compared to the other Trichoderma species, TVK1 demonstrated the highest ability to suppress phytopathogens, with a growth inhibition rate of 2.48 cm per day. TVK2 grows at a rate of 1.96 cm per day, whereas TVK5 grows at a rate of 1.98 cm per day. The level of antifungal volatile organic compounds produced by TVK1 spores was higher against plant pathogens compared to the other species examined. This compound inhibits the growth of plant pathogens. T. harzianum can eliminate 100% of S. rolfsii pathogens and 100% of Alternaria sp. Pathogens were reduced by 92.02% for A. niger, 94% for F. oxysporum, 100% for P. aphanidermatum, 94.07% for H. sativum, and 100% for M. phaseolina. In a detached leaf assay, TVK1 inhibited the growth of pathogens in various plant leaves, including tomato, mustard, and eggplant, when compared to both the commercially available fungicide and the control. The study confirms that the isolate TVK1 can combat various phytopathogens. Early application of T. harzianum can reduce the risk of phytopathogenic attacks on leaves and promote plant growth.

Evaluating the human neurotoxicity and toxicological interactions impact of co-occurring regulated and emerging mycotoxins

Mycotoxins can inflict harmful effects on diverse organs, and mounting evidence indicates their potential involvement in human neurodegenerative diseases. Given the common occurrence of these toxins in food, there is an increasing demand for a comprehensive assessment of their combined toxicity to enhance our understanding of their potential hazards. This research investigates mycotoxin exposure from widely consumed cereal-based products, including enniatin B (ENNB), sterigmatocystin (STG), aflatoxin B1 (AFB1), cyclopiazonic acid (CPZ), citrinin (CIT), and ochratoxin A (OTA). Employing the median-effect equation based on Chou and Talalay's mass-action law, we assessed their cytotoxicity in human SH-SY5Y neuronal cells. Notably, ENNB displayed the highest neurotoxicity (IC50 = 3.72 µM), followed by OTA (9.10 µM) and STG (9.99 µM). The combination of OTA + STG exhibited the highest toxicity (IC50 = 3.77 µM), while CPZ + CIT showed the least detrimental effect. Approximately 70 % of tested binary combinations displayed synergistic or additive effects, except for ENNB + STG, ENNB + AFB1, and CPZ + CIT, which showed antagonistic interactions. Intriguingly, the senary combination displayed moderate antagonism at the lowest exposure and moderate synergism at higher doses. OTA exhibited predominantly synergistic interactions, comprising approximately 90 %, a noteworthy finding considering its prevalence in food. Conversely, ENNB interactions tended to be antagonistic. The most remarkable synergy occurred in the STG and CIT combination, enabling a 50-fold reduction in CIT dosage for an equivalent toxic effect. These findings highlight the biological relevance of robust synergistic interactions, emphasizing the need to assess human exposure hazards accurately, particularly considering frequent mycotoxin co-occurrence in environmental and food settings.

Distribution of antibiotic resistant bacteria and genes in sewage and surrounding environment of Tórshavn, Faroe Islands

Several studies have investigated the effects of swimming in sewage-polluted recreational beach water, highlighting the associated health hazards. To mitigate potential pathogen transmission, it is imperative that the polluted water is released away from recreational waters and foreshores, where children tend to play. At present, domestic sewage in the Faroe Islands solely undergoes primary wastewater treatment within primary settling tanks before being discharged into the ocean. Effluents are a major anthropogenic source of antibiotic resistance genes and antibiotic resistant bacteria, which are released into the environment. The aim of this study was to investigate antibiotic resistant Gram-negative bacteria and antibiotic resistance genes in influents and effluents of wastewater subjected solely to primary treatment, along with their release into the environment during both summer and winter. Water samples were collected from influents and effluents as well as with increasing distance away from the wastewater outlet and from nearby tidepools. Samples were cultured on MacConkey agar with four different antibiotics for detection of antibiotic-resistant bacteria and antibiotic resistance genes were quantified by droplet digital PCR. All multi-drug resistant bacteria were identified using the API 20E kit. We observed an overall decrease of the abundance of Gram-negative bacteria from the effluents compared to influents, however, we observed the opposite trend in the antibiotic resistance genes. Antibiotic resistant bacteria and antibiotic resistance genes in addition to multi-drug resistant bacteria were found in the surrounding oceanic and several terrestrial tidepool samples. Of the multi-drug resistant bacteria, we found, e.g., Escherichia coli, P. aeruginosa, and A. hydrophila species, which can be pathogenic, potentially causing an infection if encountering a host. These results indicate a relatively wide pollution range of the effluents from the septic tank and treated sewage released into the environment, posing a potential hazard for both humans and wildlife.

Dynamic evacuation path planning for subway station fire based on IACO

Fire in subway stations is the most serious type of accident causing casualties, and traditional static evacuation paths are no longer able to guarantee evacuation safety. To solve this problem, this study proposes an improved ant colony algorithm (IACO), which dynamically adjusts the evacuation paths by combining the simulation results of simulation software (PyroSim), and extends the available safe evacuation time of the personnel in a limited way. First, PyroSim is used to simulate the subway station hall and platform fire scenarios with the temperature, carbon monoxide (CO) concentration, and visibility at each location, obtained from twelve sets of monitors. Improvements in the pheromone concentration and update strategy of the ant colony algorithm (ACO) can improve the accuracy and convergence speed of the algorithm. Optimal path planning is achieved by the IACO, and then evacuation paths are dynamically adjusted by comparing the time at which each monitoring point on the path reaches the human hazard thresholds. Finally, until no adjustments can be made to obtain an evacuation path that extends the available safe evacuation time for personnel in a limited way. Compared to the traditional static evacuation path, this study provides a dynamic evacuation path that takes into account the real-time changes of fires in subway stations. This dynamic evacuation path planning approach will be put into use in subway stations before the accident to provide guidance on fire safety in subway stations and to provide contingency plans for emergency evacuation.

(Non)targeted Chemical Analysis and Risk Assessment of Organic Contaminants in Darkibor Kale Grown at Rural and Urban Farms.

This study investigated the presence and human hazards associated with pesticides and other anthropogenic chemicals identified in kale grown in urban and rural environments. Pesticides and related compounds (i.e., surfactants and metabolites) in kale samples were evaluated using a nontargeted data acquisition for targeted analysis method which utilized a pesticide mixture containing >1,000 compounds for suspect screening and quantification. We modeled population-level exposures and assessed noncancer hazards to DEET, piperonyl butoxide, prometon, secbumeton, terbumeton, and spinosyn A using nationally representative estimates of kale consumption across life stages in the US. Our findings indicate even sensitive populations (e.g., pregnant women and children) are not likely to experience hazards from these select compounds were they to consume kale from this study. However, a strictly nontargeted chemical analytical approach identified a total of 1,822 features across all samples, and principal component analysis revealed that the kale chemical composition may have been impacted by agricultural growing practices and environmental factors. Confidence level 2 compounds that were ≥5 times more abundant in the urban samples than in rural samples (p < 0.05) included chemicals categorized as "flavoring and nutrients" and "surfactants" in the EPA's Chemicals and Products Database. Using the US-EPA's Cheminformatics Hazard Module, we identified that many of the nontarget compounds have predicted toxicity scores of "very high" for several end points related to human health. These aspects would have been overlooked using traditional targeted analysis methods, although more information is needed to ascertain whether the compounds identified through nontargeted analysis are of environmental or human health concern. As such, our approach enabled the identification of potentially hazardous compounds that, based on their hazard assessment score, merit follow-up investigations.

Nyiragongo Volcanic Eruption of May 22, 2021: Human Hazards.

Nyiragongo Volcanic Eruption of May 22, 2021: Human Hazards.

The emergence of urban heat traps and human mobility in 20 US cities

Understanding the relationship between spatial structures of cities and environmental hazard exposures is essential for urban health and sustainability planning. However, a critical knowledge gap exists in terms of the extent to which socio-spatial networks shaped by human mobility exacerbate or alleviate urban heat exposures of populations in cities. In this study, we utilize location-based data to construct human mobility networks in twenty metropolitan areas in the U.S. The human mobility networks are analyzed in conjunction with the urban heat characteristics of spatial areas. We identify areas with high and low urban heat exposure and evaluate visitation patterns of populations residing in high and low urban heat areas to other spatial areas with similar and dissimilar urban heat exposure. The results reveal the presence of urban heat traps in the majority of the studied metropolitan areas, wherein populations residing in high-heat exposure areas primarily visited other high-heat exposure zones. Specifically, cities such as Los Angeles, Boston, and Chicago were particularly pronounced as urban heat traps. The results also show a small percentage of human mobility to produce urban heat escalation and heat escapes. The findings from this study provide a better understanding of urban heat exposure in cities based on patterns of human mobility. These findings contribute to a broader understanding of the intersection of human network dynamics and environmental hazard exposures in cities to inform more integrated urban design and planning to promote health and sustainability.

Uncertainty Factors of a Finite Element Model using the Fuzzy Analysis Method

The recent advancement in manufacturing technology in the automotive and aerospace sectors has led to the invention of advanced structured material, which is lightweight and a complex geometry model that can be manufactured. As it is related to human safety and hazards, the need for uncertainty analysis in a structure before and after a manufacturing process is a primary concern. Thus, this paper analyzes the uncertainty parameters of a meshed finite element model in the geometry, boundary condition, load, and material properties. An uncertainty analysis numerical tool, the fuzzy analysis method, is applied in Excel-VBA as the simulation platform. Each uncertainty parameter is in a range of numbers, with a maximum and minimum value as the limit. The α-cuts determine the fuzzy analysis output on the membership function. The deterministic value of the variable is implemented for comparison purposes. The simulation result for the von-Mises stress analysis has significantly impacted the uncertainty analysis as its curve has surpassed the yield strength limit of the material. The simulation output for the displacement has a more considerable uncertainty dispersion when compared to the other results. This study helps to find a better security margin of a structure for its sustainability in the future.

A proposed method for calculating the voltage and current distributions of grounded and isolated networks subjected to line‐to‐ground faults

AbstractOne crucial objective of this article is to present simplified and accurate approaches to study the current distribution and ground surface potential around the area surrounding an earthed and isolated system in case of a line‐to‐earth fault. The present study is done in the case of uniform and two‐layer soils. Suggested models for calculating the distribution of the earth's surface current density, step, and touch voltages in grounded and isolated systems are presented, discussed, and adapted. The contact and arc resistances of line to ground faulty conductors are considered. Rods and/or grounding grids usually do grounded systems. The impact of both step and touch potentials and current density are investigated in this article. The methods of the calculations are based on the electrical concepts, the charge simulation method, and the imaging procedure for the grounding system. The suggested method can be considered a novel and simple technique for calculating the current distributions of the ground surface during line to ground fault. The results agree with those obtained by others, with the advantage of the proposed algorithm for its ease of application and simplicity. 3‐D dimensions’ contours of the current density and the electric potential on the earth surface around the faulty point are presented in case of homogeneous and two layers’ soil. Finally, this article's novelty is to devise a method for calculating the step and touch potentials and current density around the point of contact of the conductor carrying the electric voltages in the event of faults occurring in the electrical network, whether the network is grounded or isolated. Such faults of electrical networks may cause human hazards.

Impacts of cyanobacterial metabolites on fish: Socioeconomic and environmental considerations

AbstractThe increasing global population has led to rising demand for food, particularly protein. As an excellent source of protein, fish play a crucial role in meeting this demand, making aquaculture a highly impactful industry. Floating cages have been developed as a method of fish management and production to achieve high productivity and volume. However, these intensive fish farming practices can contribute to eutrophication, leading to changes in primary producers and promoting the excessive proliferation of cyanobacteria. Cyanobacteria blooms pose significant consequences to aquatic ecosystems, including potential risks to fish exposed to harmful cyanobacterial metabolites. Cyanobacterial metabolites encompass various chemical classes, such as terpenoids, carotenoids, alkaloids, cyanopeptides, amino acids, organophosphates, macrolides, and lipopolysaccharides. Some of these compounds' toxicity and impact on fish farms still need to be better understood. Cyanotoxins and off‐flavour compounds in fish farms can pose risks to water and fish quality and potential health hazards for humans throughout the food chain. Therefore, cyanobacteria in fish farms can have significant economic, environmental, and public health implications. This review examines the concerns associated with cyanobacterial natural products in fish farming, including off‐flavours, known cyanotoxins, and other potentially toxic compounds, while exploring their socioeconomic and environmental risks.

Identifying disaster risk factors and hotspots in Africa from spatiotemporal decadal analyses using INFORM data for risk reduction and sustainable development

AbstractThe incidence and magnitude of hazards in Africa are escalating. Extant knowledge base of disaster risk (DR) trends, factors, and hotspots is lacking for the continent. Here we applied random forest machine learning regressions, spatial stratified heterogeneity, and hotspot analyses on INFORM data to identify DR patterns, factors and interactions, and notable risk hotspots. We show that although DR is generally decreasing in Africa, the Eastern, Southern, and Western regions record increasing DR. Physical exposure to floods, epidemics, and violent conflicts are hazard drivers of DR in Africa. Other significant DR drivers are mostly clustered under vulnerable groups and poor infrastructural coping capacities. Human hazards interact with other factors, exhibiting the highest influences on DR. Precisely, 19 out of 53 African countries in this study are DR hotspots. Eritrea is identified as a new hotspot. Targeted policies, resilience building, vulnerability reduction measures and comprehensive sustainability‐infused solutions are required for DR reduction and sustainable development in Africa.