Human Experience Research Articles

Linguistic Denotation as an Epistemological Issue

Abstract Linguistic denotation is discussed as an epistemological issue that arises from the philosophy of external realism and the reification of language as a communication tool. Together, these serve as a foundation for viewing language as a sign system used for knowledge representation, when denotation is seen as the semantic property of linguistic signs – indication or reference to something, such as a thing (event, process, activity) or a concept. However, since neither the concept of sign in semiotics nor the concept of knowledge in philosophy (let alone the concept of concept itself) has a uniformly accepted informative definition, the concept of denotation, viewed by many as an implied semantic property of the linguistic sign, is highly controversial. It is argued that the reification of linguistic signs is a poor starting point in our attempts to understand language, not as a tool in the service of the mind, but as a mode of existence of humans in the world as an image of language.

Classification modeling of valve internal leakage acoustic emission signals based on optimal wavelet scattering coefficients

In order to achieve acoustic emission detection in valve internal leakage, it is essential to extract features, and establish an accurate mathematical model. Current valve internal leakage acoustic emission signal (VILAES) classification models mostly rely on human experience for selecting features, resulting in low accuracy for small leakage conditions. This paper combines the wavelet scattering transform (WST), Relief-F algorithm and AdaBoost.M1 algorithm, and proposes to use the optimal wavelet scattering coefficients as features to establish the VILAES classification model accurately for small leakage. Firstly, the first three order wavelet scattering coefficients of the VILAES are automatically extracted using WST and are transformed into one-dimensional features. Secondly, the Relief-F algorithm is employed to select the optimal feature subset. Finally, the optimal wavelet scattering coefficients and pressures are used as inputs to establish a classification model for VILAES and achieve an accuracy over 96.80% for small leakage.

Back to the basics: Addressing our individual and societal despair.

It started with a simple question on social media, "How is everybody doing?" (Elmo [@elmo], 2024). With this basic check-in from one of our most beloved Sesame Street characters, Elmo was able to reach millions of people and elicit responses that gave words to the feelings that the authors have been personally experiencing and noticing within my behavioral health (BH) colleagues and patients for some time now. Quite simply, we are struggling. Responses to Elmo's collective check-in demonstrated the depths of the current human experience, ranging from individual sadness, trauma, existential crises, despondence, mere survival, disbelief, and societal despair. Resilience for BH providers is possible if we return to the basics, what we are foundationally trained to do, and what Elmo reminded us works so well: facilitate human connection within ourselves, with our colleagues, with our patients, and to continue to advocate for this connection at a systemic level. Exploring fundamental questions about our well-being, showing empathy for each other's pain, and openly acknowledging our shared struggles allows for a way through this, together. As we practice these efforts at the individual level, broader policies to support the BH system must follow to offer an effective, resilient, and enduring BH system necessary for the world we live in. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Experiential AI: Between Arts and Explainable AI

Abstract Experiential artificial intelligence (AI) is an approach to the design, use, and evaluation of AI in cultural or other real-world settings that foregrounds human experience and context. It combines arts and engineering to support rich and intuitive modes of model interpretation and interaction, making AI tangible and explicit. The ambition is to enable significant cultural works and make AI systems more understandable to nonexperts, thereby strengthening the basis for responsible deployment. This paper discusses limitations and promising directions in explainable AI, contributions the arts offer to enhance and go beyond explainability and methodology to support, deepen, and extend those contributions.

Evolving Narratives: Intersection of Gender and History

This study explores the evolution of gender roles and identities through historical scholarship, analyzing both seminal and contemporary studies. It highlights the dynamic and complex nature of gender as a social construct across different periods and cultures. The study emphasizes the need for a global perspective and interdisciplinary insights to enrich the historiography of gender. It provides a nuanced understanding of the past, encouraging a more inclusive and critical approach to historical narratives. The study reaffirms the vital role of historical analysis in illuminating the intricate interplay between gender and society, offering valuable contributions to the discipline of history and fostering a deeper appreciation for the complexity of human experiences through time.

Pancha Kosha: An Exploration of Traditional Indian Knowledge on the Five Layers of Human Existence

Pancha Kosha: An Exploration of Traditional Indian Knowledge on the Five Layers of Human Existence

Privacy-preserving deep learning approaches for effective utilization of wearable health data

Wearable technology can significantly impact human existence by allowing for innovative perspectives on the outside world, such as through the use of augmented reality (AR) programs. Electronic gadgets that are worn as clothing, gadgets, or even incorporated into our bodies are called wearable gadgets. While there are many prospective advantages to smartwatches, their widespread and continuous use raises several privacy problems as well as complex data protection hurdles. Among the newer areas of healthcare informatics involves cognitive computation, which uses biological as well as physical information to autonomously track an individual's emotional status in mobility settings. While effective computation technologies hold great promise for enhancing everyday life, privacy problems and challenges must be addressed before analyzing physical information. Federated knowledge is a viable option for creating high-performing algorithms while protecting people's confidentiality. We used federated training to analyze cardiac activity information that was gathered from smart wristband tracking of anxiety levels during various situations. By protecting the confidentiality of information, we were able to accomplish promising outcomes when implementing federated training in Internet of Things-based wearable physiological tracking devices.

Doing Language(s) and Other Communicative Practices

Abstract Enlanguaged practices bring together social semiosis working as an interfacial verge or axle for even greater domains of human existence. They have mental, bodily and communicative aspects, mingle with respective practices and thus bring them all together. 4E approaches to practices help to couple them. On the one hand embodying consolidates bodies and things while on the other enacting results in processes and practices. Linguistic bodies and things are shaped as nouns and nominal forms while processes and practices mold as verbs, predicatives and other rhematic formats.

Climate therapy: Developing a climate change charter for Cancer Trials Ireland (CTI).

e23214 Background: Climate change is a threat to human existence. Healthcare is the 5th leading cause of CO2 emissions globally, while clinical trials generate the equivalent of half the CO2 emissions of Denmark. Consequently, both enterprises represent significant, potentially modifiable, causes of climate change. In response to this climate toxicity (PMID 36773799), CTI launched the National Green Cancer Clinical Trials Initiative in 2022. A climate charter, which was to consist of a living document of actionable areas, was commissioned by the CTI board to implement them. Methods: Carbon footprint touch points of CTI’s activity on climate change were identified such as travel, procurement, energy use, financial management. An online scoping review of existing academic and non-academic sustainability initiatives, funding agency and national policy documents, peer reviewed and grey literature sources was conducted using the terms climate change and sustainability. Action points were categorised and collated. No exemplar climate charters for clinical trial organisations were identified in the search. Results: 5 pillars of interaction with sustainability initiatives were evident. These were education, engagement, empowerment, embedding, and emphasising. These pillars related to 8 themes for climate smart involvement by CTI staff and members. Personal commitment to sustainability at an individual level eg dietary choices, EU climate pact participation. Trial design and management eg sustainability assessment & integration into protocols Recycling and waste management at central office and sites. Energy and water use eg optimise computing infrastructure, prioritise low carbon sources. Procurement and contracts eg promote green purchasing, integrate environmental and social sustainability clauses in contracts, sustainability assessment of financial services including pensions Meetings and conferences eg prioritising virtual meetings, select conference venues and accommodation with environmental certs. Commuting and business travel. Outreach eg, to University partners, trainees, network with Green Trial groups. Conclusions: The climate charter provides a structure to facilitate sustainability integration at CTI. This living document registers existing activities, highlights areas for engagement, facilitates horizon scanning and outreach to emerging initiatives, empowers staff , and demonstrates an organisational commitment to climate smart, clinical trial conduct.

Resilience in Agriculture Amidst and Beyond the COVID-19 Pandemic: A Comprehensive Review of Research Trends and Objectives

Abstract The COVID-19 pandemic has significantly impacted all facets of human existence, notably the agricultural sector. The term “resilience” has regained popularity as a means of coping with pandemics. The primary objective of this article is to discern and compile scholarly works pertaining to the concept of resilience in agriculture, specifically in the context of the ongoing COVID-19 pandemic. Furthermore, it seeks to establish connections between various research domains and the specific research goals outlined in the synthesis articles. The publishing data utilized in this study comprises of research publications written in the English language, with a specific focus on the field of agriculture. The data was sourced from reputable databases such as Scopus, ScienceDirect, and Wiley, covering the period from 2020 to 2023. There is a total of 110 articles that meet the specified inclusion criteria. The articles were stored on the Mendeley platform and afterwards subjected to bibliometric analysis using the VOSviewer software. In addition, it is important to note that papers are categorized according to their geographical location and the specific aims of the research. The primary findings indicate that resilience has been a longstanding research focus, which has regained popularity due to its association with COVID-19. The number of publications pertaining to COVID-19 is steadily rising, with a focus on several keywords including market disruption, case studies, community-supported agriculture, agroecology, and disaster recovery. study primarily targets countries in the Asian continent based on their geographical location. The result shows mostly revolve around investigating the effects of lockdown measures on agricultural production, the agri-food supply chain, livelihoods, and market access. Several study objectives were also focused on examining the resilience of various farming systems and smallholder farmers. This analysis serves as a valuable point of reference for future research pertaining to the resilience of the agricultural sector in the face of various shocks.

Ductal carcinoma in situ: Molecular and cellular basis of malignancy.

e12582 Background: The goal of our study is to improve the diagnosis and treatment of DCIS through the identification of the factors driving its invasion and metastasis. Methods: We utilized the Mouse INtraDuctal (MIND) model to investigate the mechanism(s) by which some DCIS become invasive while others remain indolent. This model closely replicates the human condition by injecting non-invasive epithelial cells from patients into mouse mammary ducts to form in situ lesions. In some cases, these cells will display invasive behavior by overcoming the natural barriers of myoepithelium. To compare these two processes, we performed single-cell (sc) RNA-sequencing analysis of 60,000 cells from the pre-transplant time-point representing 17 DCIS (11 became invasive, 6 remained non-invasive). We also performed scATAC/RNA sequencing of a DCIS with associated IDC. Results: Our analysis revealed that the proportion of endothelial cells was higher in cases that became invasive, while the proportion of plasma and T cells was higher in those that remained non-invasive (t-test; P<0.05). This finding suggested that invasive cells reprogrammed the immune microenvironment to exclude immune cells as a means of evading immune surveillance. Additionally, we performed cell-cell interaction (CCI) analysis by CellPhoneDB. This analysis revealed highly ranked CCIs in invasive cases, including luminal cell interactions with pericytes via Wnt5A-SFRP1. On the other hand, highly ranked CCIs in non-invasive cases included HR-positive luminal cell interactions with T cells via CD226-Nectin-2 and CD96-Nectin1. Notably, CD226 and CD96 are T cell receptors that enhance CD8+ T cell activity. These results support the potential role of T-cell interactions with DCIS luminal cells in preventing their invasive transition. We conducted additional analysis of sc-RNA-sequencing data using a stem cell-based gene signature algorithm called CytoTRACE. Our analysis revealed that invasive cells were enriched in cell clusters with significantly higher stem cell scores than non-invasive cells. In another analysis of a patient DCIS with associated IDC using sc-ATAC and RNA sequencing, we discovered that the open chromatin regions in the stem cell cluster were enriched for FOXA1 binding motifs. This cluster also had the highest expression of two pioneer factors (FOXA1 and GRHL2), NEAT1 (paraspeckle protein), ERBB2, 3,4, and ANKRD30A (cell surface protein). Our findings suggest that the pioneer factors FOXA1 and GRHL2 play a crucial role as transcriptional drivers of stemness. Additionally, the ANKRD30A could be used to isolate stem cell clusters to validate their self-renewal potential. Conclusions: DCIS progression is facilitated by interactions between stromal, immune, and epithelial cells, which lead to epigenetic and transcriptional changes. This results in the formation of stem-like cells that are characterized by their plasticity and invasive capacity.

“My mind is not in my brain”: exploring consciousness with children using creative research methods

ABSTRACT The focus on the brain over the last few decades has seen an overclaiming of the human condition through brain-based research. Researching consciousness is an enquiry into who we are, our subjective experiences and our relationality with others and the world. In typical and child development research, materialist orientations dominate the field, assuming brains as the manufacturers of consciousness. Qualitative research has the potential to engage children in consciousness research, while interrogating typical constructionist, realist and materialist orientations. In this article we discuss using creative research methods for exploring aspects of phenomenal consciousness, such as self and mind, with children in a UK primary school. We share findings in relation to how children understand consciousness, how consciousness bears on self for children in the study, and how children experience and perceive the mind/body.

A Comprehensive Review of Preclinical Models for Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is a reproductive, metabolic, and endocrine disorder with unclear aetiology. PCOS, the most common cause of female reproductive and metabolic disorders, is known to affect more than one in ten women globally. PCOS and associated clinical manifestations are probably underdiagnosed despite their high occurrence. Objective: Alternative animal models have been employed to investigate the causes of PCOS or assess potential treatments. In light of this piece of information, it is challenging to create an animal model that accurately captures all components of this condition; nonetheless, the resemblance of an animal model's biology and/or biochemical characteristics to the phenotypes of PCOS in humans may boost its applicability. Result: The key characteristics of these models are closer to human situations when compared to women with PCOS, as shown by this comparison. The creation and testing of drugs for the treatment of PCOS are necessary. Conclusion:: The overview of PCOS, current preclinical models, and appropriate models chosen in different studies to mimic various phenotypes in PCOS studies are all covered in this review paper. Additionally, we have outlined the benefits and drawbacks of PCOS animal models.

الزمانية والترجمة: ما بين المواضيعية وعدمها

Narrative theorists broadly agree that stories are important to both being and knowing. There is less agreement, however, as to exactly how deep narrative goes. The strongest narrativists—such as David Carr and Alisdair MacIntyre—argue that story is so fundamental that human existence itself has an intrinsic narrative structure. The strongest anti-narrativists—such as Galen Strawson and Peter Lamarque—suggest that narrative is merely one way of knowing among others and enjoys no privileged ontological or epistemological status. A closely related question concerns how seemingly diverse forms of narration such as fiction, history, the small stories of daily interaction and storied (or story-like) modes of cognition relate to one another. The crux of the issue, I suggest, lies in the relationship between narrative and the human experience of time. The central argument, drawing on the existential hermeneutics of Martin Heidegger and Paul Ricœur, is that narrative and the human experience of time are non-identical but intimately connected through a continuous process of existential translation. It proceeds in four stages: (1) we should distinguish between explicit, thematic storytelling and the everyday, non-thematic experience of time; (2) narration is a type of translation which thematizes and allows some interpretive possibilities to be recognized while masking others; (3) this type of translation produces narratives which are, to some extent, object-like; (4) this allows the operation of distanciation, opening the possibility of new understanding through ‘second-order disclosure’. I suggest that this existential approach can usefully inform and expand our understanding of both narrative and translation. A synopsis of this article can be found here.

Systematic Literature Review on Augmented Reality with Persuasive System Design: Application and Design in Education and Learning

Augmented Reality (AR) is an innovative technology that has gained significant scholarly attention. It uses computer-generated sensory inputs like visuals, sounds, and touch to enhance how we perceive the real world, providing a transformative impact on human sensory experiences. Motivated by the possibilities of augmented reality (AR) in the realm of the educational learning environment, this research aims to document the evolving landscape of augmented reality (AR) applications in education and training, with a specific emphasis on the incorporation of persuasive system design (PSD) elements. The study also explores the diverse technologies and methodologies for developing these applications. A systematic literature review was conducted, analyzing 44 articles following the protocol for PRISMA assessments. Four research questions were formulated to investigate trends in AR applications. Between 2016 and 2023, publications on AR applications doubled, with a significant focus on the educational field. Marker-based AR methods dominated (68.49%), while markerless methods constituted 31.51%. Unity and Vuforia were the most used platforms, accounting for 77.27% of applications. Most research papers assessed application effectiveness subjectively through custom-made questionnaires. University students were identified as the primary target users of AR applications. Only a few applications integrated persuasive elements, even for adult users. This highlights the need for further studies to fully grasp the possibilities of combining persuasive system design with augmented reality applications in education

Within or Outside the Boundaries: Exploring the Intricacies of Human-Elephant Relationship in Tania James’s Novel The Tusk That Did the Damage

Despite the fact that Human geography has long studied landscapes in relation to human identity, experience, intentions, and relationships, a change in the epistemology of spatial discourse has led to a shift in how landscapes are now defined in terms of the presence of human-animal relationships in particular locations. This study comprehends the subtle nuances of human-animal relationships by re-conceptualizing the understanding of spaces and places and negotiates the question of how the fictional elephant Gravedigger becomes known for reorganizing spaces. Based on the semiotics of literary geography and animal geography this research territorializes elephant-human geographies, delineates elephant agency inside the “animal spaces,” and examines how the elephants’ lived experiences create the “beastly places” outside the “animal spaces” in the novel The Tusk That Did the Damage (2015). It further depicts animals as powerful subjects in the wild spaces and attempts to understand how boundary breaching occurs.

QIRÂAH FÎ KHIȚÂB AL-MAR'AH: A STUDY OF GENDER ISSUES IN THE BOOK DAWÂIR AL-KHAWF

This article examines gender issues in the thoughts of Naṣr Ḥāmid Abu Zayd as stated in his book entitled Dawâir Al-Khawf Qirâah Fî Khițâb Al-Mar'ah. Naṣr Ḥāmid was originally a follower of Al-Ikhwan al-Muslimun, who later turned into a liberal intellectual figure from Egypt who was known for his controversial and controversial thoughts. This study uses a literature study which refers to several main books of his works and is added to secondary sources in the form of several writings resulting from research on the thoughts of Naṣr Ḥāmid Abu Zayd. The results of this research show that Naṣr Ḥāmid criticizes the interpretations that have developed over time, especially regarding qiwâmah, inheritance, talak, polygyny and women's private parts (hijab). According to him, women are part of the substance that is rooted in human social existence in certain historical realities. These conditions of social relations determine the position of men and women equally in the social, cultural and intellectual framework. Both are equal as complete human beings. This thinking places him at the level of progressive thought and attracts many groups, which is sometimes in harmony with the ideas of early Egyptian Muslim feminists, namely Muhammad Abduh.

Understanding Contemporary Societal Challenges with Philosophy of Trust

Abstract We argue that philosophy of trust can be employed to counter the paralysis of action ensuing out of the experience of polycrisis in the current state of international social life. Philosophy of trust can recognize the impact of the polycrisis on contemporary societies all the while that an analysis of trust inevitably takes the concrete life world experiences of humans as a central part of the analysis. Using the philosophy of trust as an analytic tool involves digging into relations of trust and distrust situated in concrete social environments which takes humans’ concrete experiences of trust, distrust, and breaches of trust into account all the while that its theoretical conceptualizations can pay heed to overall societal challenges. As such it provides a means to study our contemporary world of polycrisis without simplifying the social world or succumbing to paralysis. This is shown in short discussions and presentations of the five articles included in the special issue.

Understanding Contemporary Societal Challenges with Philosophy of Trust

Abstract We argue that philosophy of trust can be employed to counter the paralysis of action ensuing out of the experience of polycrisis in the current state of international social life. Philosophy of trust can recognize the impact of the polycrisis on contemporary societies all the while that an analysis of trust inevitably takes the concrete life world experiences of humans as a central part of the analysis. Using the philosophy of trust as an analytic tool involves digging into relations of trust and distrust situated in concrete social environments which takes humans’ concrete experiences of trust, distrust, and breaches of trust into account all the while that its theoretical conceptualizations can pay heed to overall societal challenges. As such it provides a means to study our contemporary world of polycrisis without simplifying the social world or succumbing to paralysis. This is shown in short discussions and presentations of the five articles included in the special issue.

The Representation of the Self in Alfred Lord Tennyson's Poetry

Literary investigation of selfhood has long reflected human identity and introspection. Alfred Lord Tennyson's self-portraits are examined in this article. Tennyson's introspective lyrics illuminated Victorian consciousness during immense social and intellectual change. This article examines Tennyson's complex self-representation in selected poems. The essay places Tennyson's poetry in the context of Victorian literature and ideas, stressing selfhood's changing roles. It examines Tennyson's introspective study of emotions, wants, doubts, and fears. According to Tennyson's poems, the self's relationship to nature, society, and history is examined. A thematic analysis of seclusion, nostalgia, and existential pondering illuminates Tennyson's interest in the self's place in the ever-changing universe. It explores Tennyson's approach to memory and identity, showing how his poetic personas traverse the complex relationship between past and present identities. We conclude with Tennyson's poetics of change, where the self transforms and renews in the face of life's obstacles and uncertainties. This article illuminates Tennyson's literary language and influences on Victorian selfhood through attentive readings and critical analysis. It shows how Tennyson's verses reflect the Victorian self's complexity, inconsistencies, and existential aspirations; they resonate beyond time and invite readers to consider their identities in the ever-changing tapestry of human experience.