The growing relevance of socio-ecological systems (SESs) thinking reflects both the challenges of an anthropogenic poly crisis and attempts to understand the complexities of societal development in an era of globalisation. The article begins by suggesting there are two related variants of SES thinking—relationships between the natural and human worlds (Variant 1) and whole social and human system analysis using metaphorical transfer and theorisation of natural ecological principles (Variant 2). This article elaborates Variant 2 through the development a social ecosystem model (SEM) applied to post-compulsory education and skills development. An exploration of the SEM is conducted through a review of the literatures on ‘Learning Ecologies’ to assess the strengths and limitations of this human ecological approach. Perceived limitations are addressed by the development of the SEM that adds a political economy dimension to the learning ecological model, which is then applied to the field of learning and skills in the English context in support of an inclusive and place-based approach to vocational education and training (VET). The article concludes by suggesting that the SEM can be further expanded by its application to transitioning to more sustainable futures, being developed by scholars of indigenous communities and populations of the Global South, that arguably brings Variant 2 of SESs thinking closer to Variant 1.