Huge Catalogs Research Articles

Finding new genes in the nervous system by cDNA analysis

There are several methods to isolate c DNAs that do not require prior biochemical characterization of their protein products, including isolation of new members of particular protein families based on sequences of known members, selection of specific clones by differential screening, and shotgun analysis of a particular c DNA population. This third approach will produce a huge catalogue of c DNA sequences and anatomical data that will be useful to investigators with diverse interests. Recent methodological advances allow c DNAs to be isolated and sequenced rapidly. These methods, coupled with fast and reliable techniques for in situ hybridization histochemistry, should permit c DNA catalogues to be assembled efficiently.

Third Programme: First Birthday

If we are a few days late in proffering birthday congratulations it is not entirely inappropriate, for the Third Programme itself does not insist on rigid punctuality. And if we forego a review of the year that ended on September 29th it is mainly in order to avoid printing a huge catalogue of major works and interesting performances. The temptation to reminisce is of course enormous, but to examine in detail one month of the Third's activity is probably more representative than to gloat over a year's masterpieces, curiosities, rareties, experiments.