In order to alleviate the serious congestion in the evacuation process of high-rise buildings in today’s society when a fire occurs, a hotel building in Xi’an was used as the background in this research process, and the disaster escape software Pathfinder was used to conduct a fire on all personnel in the hotel. The subsequent evacuation simulation shows that different behaviors and different groups of people need to spend time in the process of escape and the actual situation of the stairs, walkways, safety exits and other locations in this situation. Combined with the comparative analysis of the required evacuation time and evacuation width of the building in the “Code for Fire Protection Design of Buildings”, it is determined that the fastest evacuation of people can be carried out in 657s.