Building space heating and cooling power consumption is growing due to population and economic growth. Integrating phase change materials (PCMs) into various building envelope components is being explored to enhance thermal energy storage capacities. Specifically, roofs exposed to direct sunlight significantly promote thermal energy transfer to the interior, increasing the space heating and cooling requirements. In this study, thermal energy storage performance of a biaxial voided roof slab integrated with PCM is experimentally investigated under ambient conditions and compared with a normal reinforced concrete (RCC) without PCM. PCM selection, characterization, and metal void former development are performed, followed by macroencapsulation and integration into the roof slab. Thermal performance measures are evaluated, including temperature profile, heat flux, thermal load, time lag, and decrement factor. Financial viability indicators such as electricity cost savings, payback period, and CO2 emissions savings are also assessed. The results show PCM integrated biaxial voided roof slab reduces interior temperature by upto 7.2 °C during sunny hours, heat transfer to the interior by upto 60.6 %, and thermal load by upto 54 %. In addition, considering heating and cooling, it offers an average daily saving of 0.06 USD/kWh/m2 and a payback period of about 5.7 years. Further, it gives CO2 emissions savings of upto 13.7, 12.3, and 4.3 kgCO2/kWh for lignite-, coal-, and natural gas-fired power plants. Furthermore, its mean time lag is 4.2 h, with a decrement factor of 0.75 compared to 3.9 h and 0.85 for the normal RCC unit. The study makes significant contribution to knowledge by providing a unique, simple yet highly effective PCM macroencapsulation integration technique for roof slabs and insights into its thermal performance under the hot weather conditions.