Hot Foot Research Articles

Hot foot means trouble brewing?

In Brief Implanted ID chips approved for human use…advanced practice nurses may need doctorates…antiulcer drugs linked to community-acquired pneumonia…and more.

Hidradénite eccrine à Pseudomonas de l’enfant révélatrice d’une leucémie aiguë lymphoblastique

We report the case of a Pseudomonas (P.) aeruginosa eccrine hidradenitis in a child, or a "Pseudomonas Hot Foot Syndrome", revealing an acute lymphoblastic leukemia. A 10 year-old girl consulted for the sudden onset of painful and necrotic palmoplantar nodules in a context of fever and shivering. Histology of a cutaneous biopsy found necrosis of the eccrine glands and, on culture, P. aeruginosa. The blood count revealed pancytopenia and the myelogram acute lymphoblastic leukemia. All the hemocultures and other microbiological samples were negative. The cutaneous signs had appeared 48 hours after bathing in an aquatic amusement park. Diagnosis of Pseudomonas eccrine hidradenitis, or "Pseudomonas Hot Foot Syndrome" was retained, although the local sanitary authorities were not able to demonstrate P. aeruginosa contamination of the water in the park. Lesions evoking juvenile Pseudomonas aeruginosa eccrine hidradenitis without obvious traumatic factor must lead to the search for P. aeruginosa contamination from water and the subsequent sanitary and epidemiological consequences. Furthermore, severe P. aeruginosa cutaneous infections in children must also lead to the search for an underlying immunosuppression and notably an acute leukemic process.

Lessons from hot feet: A note on tissue remodeling

Lessons from hot feet: A note on tissue remodeling

Hot Feet from Pseudomonas in a Wading Pool

Pseudomonas aeruginosa can flourish in heated pools or hot tubs with inadequate chlorination, causing folliculitis in bathers. These authors describe a

Diplomacy

Chiefly for the wrong reasons, diplomacy has recently made some notable incursions into international relations programmes at British universities. For, in the field of money-spinning taught Master's degrees, this subject has been perceived as a crowd puller. Out there, beyond the European Community with its aggravatingly-low fee levels, are, it is calculated, many who will be attracted by an MA with 'diplomatic' in its title. With some ground, it is believed they see that sort of degree as a passport to a position in the much-sought-after diplomatic ranks. Furthermore, in the same regions lie beginning diplomats who could be said to need some vocational underpinning, not to mention those longer-employed in diplomacy who would benefit in mid-career from intellectual refreshment. The British Statue of Education beckons, its own distinctive torch held high aloft. And, to ensure that its light does not go unnoticed, Vice-Chancellors despatch glossy brochures to the British Council and their recruiting officers, hot foot, to distant parts.

Isolation of Mycoplasma synoviae from infectious synovitis of chickens

This report describes the first isolations of Mycoplasma synoviae from the synovial sheaths and joints of commercial chickens affected with synovitis in Australia. Over 4 years 3 separate outbreaks were investigated in which up to 20% of birds exhibited clinical signs of poor growth and "hot foot" syndrome (swollen inflamed footpads). Once an outbreak occurred, chronic infection of the farm usually ensued. Grossly the hocks and footpads were swollen by a purulent exudate and associated inflammatory changes with histological features of a severe acute synovitis. Seroconversion of the flocks occurred at the time of the development of lesions. M. synoviae specific antibodies were demonstrated by ELISA in the joint fluid of affected birds. It is concluded that the cases described are similar to avian infectious synovitis syndrome caused by M. synoviae previously described overseas.

Physical dependence on diazepam in the dog: precipitation of different abstinence syndromes by the benzodiazepine receptor antagonists Ro 15–1788 and ZK 93426

1. The effects of the benzodiazepine receptor antagonists Ro 15-1788 (flumazenil) and the beta-carboline ZK 93426 were compared in dogs before and after chronic treatment with diazepam. 2. In diazepam-naive dogs, the most prominent behavioural alterations occurring during or after i.v. infusion of Ro 15-1788 up to a dose of 20 mg kg-1 were transient sedation, ataxia, and 'hot foot' behaviour, whereas behavioural alterations observed after ZK 93426 were not different from those observed after i.v. infusion of vehicle alone. This indicates that, in contrast to Ro 15-1788, ZK 93426 did not exert partial agonistic activity at benzodiazepine receptors. 3. In dogs treated 3 times daily with diazepam, 1 mg kg -1 orally, for 1 week, both benzodiazepine antagonists precipitated abstinence symptoms but the number and severity of withdrawal signs induced by Ro 15-1788 were greater than with ZK 93426. 4. In dogs treated 3 times daily with diazepam, 2 mg kg-1 orally, for 2 weeks, severe abstinence symptoms were precipitated in all animals by infusion of either antagonist but differences were found in the type of the symptoms: Ro 15-1788 induced rigid postures or rigid walking with increased muscle tone, tremor, twitches and jerks, whereas ZK 93426 did not alter motility but induced generalized myoclonic jerks and tonic-clonic seizures. A generalized tonic-clonic seizure was also observed in one dog of the trial with infusion of Ro 15-1788. 5. Plasma level determinations during chronic treatment diazepam showed marked accumulation of the major active metabolite desmethyldiazepam, whereas diazepam levels were at least 15 times lower, which might suggest that desmethyldiazepam was responsible for the development of physical dependence on diazepam.

Physiological adjustments of young men to five-hour desert walks.

Seven young men undertook a desert walk of 30 km at a rate of 100 m/min. Six finished; the seventh stopped after 24 km. Each satisfied his thirst with cool tap water each hour. Periodic observations included metabolic rate, blood pressure, heart rate, rectal and skin temperature, body weight, and volume of water drunk. Hand sweat was collected each hour and body sweat residues on the skin were collected at the end of the walk. Subjective reports revealed portents of breakdown: aching muscles, painful joints, hot or blistered feet, hunger, and boredom. Cardiovascular adjustment and temperature regulation maintained tolerable conditions. The volumes of water evaporated by the 5-h walkers were about the same. Wet bulb temperatures were below 25 degrees C; all sweat evaporated and was available for temperature regulation. The volume of water drawn from body reserves was closely correlated with concentration of chloride in body sweat; the volume of water that satisfied thirst maintained osmotic pressure.

Proceedings: Gangrene of the feet in diabetics.

Three etiological factors–ischemia, peripheral neuropathy, and infection–underlie the development of gangrene of the feet in diabetics. The emphasis on each factor varies from patient to patient. A clinical classification based on the temperature of the foot divides patients with gangrene of the feet into three groups that occur with equal frequency: (1) necrosis in a cold foot, (2) necrosis in a hot foot, and (3) necrosis in a warm foot. In the first group, a major amputation is the inevitable result. Local excision and preservation of part of the foot is possible in all patients in the second group. It is worth attempting a local excision in the third group, as healing will occur in half the cases.

Gas Warfare

Surfeited with the unprecedented horrors of World War II, the moral consciousness of the Western world has become jaded. There was a time-in the mid-1930's—when it protested Mussolini's practice of forcing castor oil down the throats of political prisoners and then parading them in public while stalwart Fascists watched the spectacle with sadistic glee. During his Ethiopian campaign, Mussolini's use of irritant gases to give brave but ill-shod and illequipped Ethiopian tribesmen “the hot foot” was also condemned by a moral conscience that had not yet learned to accept the organized cruelty of World War II—the terror bombings of both British and German cities, and the unexampled savagery of the German invasion of Russia, widely heralded by Nazi propaganda as a great anti-Communist “crusade.“

L'Asthme dans l'enfance.

This brief book in French on the clinical features and therapy of asthma in infants and children is written by a practitioner for practitioners. It is largely based on his personal experience. The bibliography consists of 17 references exclusively from the French literature. No attempt is made to deal comprehensively with the subject matter from the international point of view. The clinical portion consists of a rather elaborate classification of different types of asthma, with their prognosis. This is the most detailed part of the book, and the one in which the author's approach and that of the American School would be most in accord. The section on therapy is primarily of interest in pointing up the differences in rationale for therapy and in recalling, what to us, are almost historic forms of treatment. These include hot applications to chest and neck, hot foot baths, cupping, bleeding, sterile abscess for

Effect of hot foot baths on vasomotor rhinitis: Observations by means of the epinephrine probe test: Muck, O.: Ztschr. f. Hals-, Nasen- u. Ohrenh. 37: 357, 1935

Effect of hot foot baths on vasomotor rhinitis: Observations by means of the epinephrine probe test: Muck, O.: Ztschr. f. Hals-, Nasen- u. Ohrenh. 37: 357, 1935