ABSTRACT Wayside hot-box detectors (HBDs) are devices used to assess the health of railcar components including bearings, axles, and brakes by monitoring their temperatures. HBDs use infrared (IR) sensors to record the temperatures of railroad bearings. Bearings that trigger an alarm or exhibit warm trending are removed and sent for inspection. In many cases, no discernable defects were found in the flagged bearings. Motivated by this finding, an investigation was conducted which included performing a controlled field test as well as exhaustive laboratory testing utilizing an HBD simulator. Data acquired from field and laboratory testing was used to evaluate the accuracy and efficacy of wayside HBDs. The results suggest that the scanning location on the bearing cup significantly affects the temperature measurement. Different calibrations for the field- and laboratory-acquired data were also explored. An optimized calibration technique along with proper IR sensor alignment can markedly improve the accuracy of HBD measurements.